Wu, A. et al. Genome composition and divergence of the novel coronavirus (2019-nCoV) originating in China. Cell Host Microbe 27(3), 325328 (2020).
CAS Article Google Scholar
Yanes-Lane, M. et al. Proportion of asymptomatic infection among COVID-19 positive persons and their transmission potential: A systematic review and meta-analysis. PLoS ONE 15(11), e0241536 (2020).
CAS Article Google Scholar
Wu, Z. & McGoogan, J. M. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA 323(13), 12391242 (2020).
CAS Article Google Scholar
Schurr, T. G. Host genetic factors and susceptibility to SARS-CoV-2 infection. Am. J. Hum. Biol. 32(5), e23497 (2020).
Article Google Scholar
Kachuri, L. et al. The landscape of host genetic factors involved in immune response to common viral infections. MedRxiv Preprint Server Health Sci. https://doi.org/10.1101/2020.05.01.20088054 (2020).
Article Google Scholar
Smatti, M. K., Al-Sarraj, Y. A., Albagha, O. & Yassine, H. M. Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis. Front. Genet. 11, 578523. https://doi.org/10.3389/fgene.2020.578523 (2020).
CAS Article PubMed PubMed Central Google Scholar
Kuo, C.-L. et al. APOE e4 genotype predicts severe COVID-19 in the UK Biobank community cohort. J. Gerontol. Ser. A 75(11), 22312232 (2020).
CAS Article Google Scholar
Morton, A. M., Furtado, J. D., Mendivil, C. O. & Sacks, F. M. Dietary unsaturated fat increases HDL metabolic pathways involving apoE favorable to reverse cholesterol transport. JCI Insight. 4(7), e124620 (2019).
Article Google Scholar
Pang, S., Li, J., Zhang, Y. & Chen, J. Meta-analysis of the relationship between the APOE gene and the onset of Parkinsons disease dementia. Parkinsons Disease https://doi.org/10.1155/2018/9497147 (2018).
Article PubMed PubMed Central Google Scholar
Phillips, M. C. Apolipoprotein E isoforms and lipoprotein metabolism. IUBMB Life 66(9), 616623 (2014).
CAS Article Google Scholar
Uddin, M. S. et al. APOE and Alzheimers disease: Evidence mounts that targeting APOE4 may combat Alzheimers pathogenesis. Mol. Neurobiol. 56(4), 24502465 (2019).
CAS Article Google Scholar
Knouff, C. et al. Apo E structure determines VLDL clearance and atherosclerosis risk in mice. J. Clin. Investig. 103(11), 15791586 (1999).
CAS Article Google Scholar
Liu, S., Liu, J., Weng, R., Gu, X. & Zhong, Z. Apolipoprotein E gene polymorphism and the risk of cardiovascular disease and type 2 diabetes. BMC Cardiovasc. Disord. 19(1), 16 (2019).
Article Google Scholar
Wang, Q. Q., Davis, P. B., Gurney, M. E. & Xu, R. COVID-19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US. Alzheimers Dement. 17, 12971306. https://doi.org/10.1002/alz.12296 (2021).
CAS Article Google Scholar
Goldstein, M. R., Poland, G. A. & Graeber, C. W. Does apolipoprotein E genotype predict COVID-19 severity?. QJM Int. J. Med. 113(8), 529530 (2020).
CAS Article Google Scholar
Xiong, N., Schiller, M. R., Li, J., Chen, X. & Lin, Z. Severe COVID-19 in Alzheimers disease: APOE4s fault again?. Alzheimers Res. Therapy. https://doi.org/10.1186/s13195-021-00858-9 (2021).
Article Google Scholar
Wu, W., Wang, A. & Liu, M. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395(10223), 497506 (2020).
Article Google Scholar
Tsai, P.-H. et al. Clinical manifestation and disease progression in COVID-19 infection. J. Chin. Med. Assoc. 84(1), 38 (2021).
MathSciNet CAS Article Google Scholar
Zhou, F. et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. The Lancet. 395(10229), 10541062 (2020).
CAS Article Google Scholar
Chan, J. F. W. et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: A study of a family cluster. Lancet 395(10223), 514523 (2020).
CAS Article Google Scholar
Onder, G., Rezza, G. & Brusaferro, S. Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. JAMA 323(18), 17751776 (2020).
CAS PubMed Google Scholar
Ellinghaus, D. et al. The ABO blood group locus and a chromosome 3 gene cluster associate with SARS-CoV-2 respiratory failure in an Italian-Spanish genome-wide association analysis. MedRxiv Preprint Server Health Sci. https://doi.org/10.1101/2020.05.31.20114991v1.full (2020).
Article Google Scholar
Wang, F. et al. Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility. Cell Discovery 6(1), 116 (2020).
Google Scholar
Velavan, T. P. et al. Host genetic factors determining COVID-19 susceptibility and severity. EBioMedicine 72, 103629 (2021).
CAS Article Google Scholar
Kuo, C.-L. et al. ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank. J. Gerontol. Ser. A 75(9), 18011803 (2020).
CAS Article Google Scholar
Gkouskou, K. et al. COVID-19 enters the expanding network of apolipoprotein E4-related pathologies. Redox Biol. 41, 101938 (2021).
CAS Article Google Scholar
Kosmicki, J. A. et al. Genetic association analysis of SARS-CoV-2 infection in 455,838 UK Biobank participants. MedRxiv Preprint Server Health Sci. https://doi.org/10.1101/2020.10.28.20221804v1 (2020).
Article Google Scholar
Wang, C. et al. ApoE-isoform-dependent SARS-CoV-2 neurotropism and cellular response. Cell Stem Cell 28(2), 33142 e5 (2021).
CAS Article Google Scholar
Wang, H., Yuan, Z., Pavel, M. A. & Hansen, S. B. Cholesterol and COVID19 lethality in elderly. BioRxiv. https://doi.org/10.1101/2020.05.09.086249v1.full (2020).
Article PubMed PubMed Central Google Scholar
Figueroa, D. M., Gordon, E. M., Yao, X. & Levine, S. J. Apolipoproteins as context-dependent regulators of lung inflammation. In Mechanisms and Manifestations of Obesity in Lung Disease (eds Johnston, R. A. & Suratt, B. T.) 301326 (Academic Press, Berlin, 2019). https://doi.org/10.1016/B978-0-12-813553-2.00013-0.
Chapter Google Scholar
del Ser, T. et al. Residence, clinical features, and genetic risk factors associated with symptoms of COVID-19 in a cohort of older people in Madrid. Gerontology 67(3), 281289 (2021).
Article Google Scholar
Espinosa-Salinas, et al. Potential protective effect against SARS-CoV-2 infection by APOE rs7412 polymorphism. Sci. Rep. 12(1), 7247 (2022).
CAS Article Google Scholar
Mwer, S., Dykes, D. & Polesky, H. J. N. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acid Res. 16(3), 1215 (1988).
Article Google Scholar
Yang, Y. G. et al. Apolipoprotein E genotyping by multiplex tetra-primer amplification refractory mutation system PCR in single reaction tube. J. Biotechnol. 131(2), 106110 (2007).
CAS Article Google Scholar
The rest is here:
The association of APOE genotype with COVID-19 disease severity | Scientific Reports - Nature.com
- The Health Department website was attacked in the middle of the coronavirus pandemic - Vox.com [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Defining Coronavirus Symptoms: From Mild To Moderate To Severe : Goats and Soda - NPR [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- What Are the Symptoms of a Coronavirus Infection? - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Hotels Were Rolling Out Tools to Help Calm Travelers. Then Coronavirus Hit. - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- The Coronavirus, by the Numbers - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Opinion: Early Coronavirus Testing Failures Will Cost Lives - NPR [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Cases Surge in U.S. and Europe - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Two Emergency Room Doctors Are in Critical Condition With Coronavirus - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus: Over 1000 Cases Now In U.S., And 'It's Going To Get Worse,' Fauci Says - NPR [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- China Spins Tale That the U.S. Army Started the Coronavirus Epidemic - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Everything to Know About the Coronavirus in the United States - The Cut [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus closed this school. The kids have special needs: 'You can't Netflix them all day.' - USA TODAY [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- How Long Can The Coronavirus Live On Surfaces? : Shots - Health News - NPR [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Cost to Businesses and Workers: It Has All Gone to Hell - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- In the U.S., More Than 300 Coronavirus Cases Are Confirmed - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- How Jair Bolsonaro's Son, Eduardo, Confirmed His Father's Positive Coronavirus Test to Fox News, Then Lied About It - The Intercept [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- De Blasio Resisted on Coronavirus. Then Aides Said Theyd Quit. - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Trump Is Tested for Coronavirus, and Experts Ask: What Took So Long? - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Live Coronavirus Updates and Coverage - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Threatens Americans With Underlying Conditions - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Capitalism and How to Beat It - The Intercept [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- An essential reading guide to understand the coronavirus - Vox.com [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- N.Y.C.s Economy Could be Ravaged by Coronavirus Outbreak - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- 'A ticking time bomb': Scientists worry about coronavirus spread in Africa - Science Magazine [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- How coronavirus is affecting the restaurant business, in one chart - Vox.com [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Map: How To Track Coronavirus Spread Across The Globe - Forbes [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Testing Website Goes Live and Quickly Hits Capacity - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Map: How Many Cases Of Coronavirus Are There In Each US State? : Shots - Health News - NPR [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Live Coronavirus Updates and Coverage Globally - The New York Times [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- This Is How the Coronavirus Will Destroy the Economy - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Every Star and Public Figure Diagnosed with COVID-19: A Running List - The Daily Beast [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus: What you need to know - Fox News [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Travel updates: which countries have coronavirus restrictions and FCO warnings in place? - The Guardian [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Staff angered as Charter prohibits working from home despite spread of coronavirus - TechCrunch [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- If coronavirus scares you, read this to take control over your health anxiety - The Guardian [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- San Francisco and Bay Area will shelter in place to slow coronavirus spread - The Verge [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus spreading fastest in UK in London - The Guardian [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Businesses Face a New Coronavirus Threat: Shrinking Access to Credit - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Welcome to Marriage During the Coronavirus - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Sweeping restrictions take effect in coronavirus response as health officials warn US is at a tipping point - CNN [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- How Long Will the Coronavirus Outbreak and Shutdown Last? - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- 201920 coronavirus pandemic - Wikipedia [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus - World Health Organization [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- What Is Coronavirus? | HowStuffWorks [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus | CISA [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Is there a cure for the new coronavirus? - Livescience.com [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Shelter in Place: Some Residents in Bay Area Ordered to Stay Home - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Tracking the Impact of the Coronavirus on the U.S. - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- 8 Things Parents Should Know About The Coronavirus: Life Kit - NPR [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Spain, on Lockdown, Weighs Liberties Against Containing Coronavirus - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- New Yorks Nightlife Shuttered to Curb Coronavirus - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- How best to fight the economic impact of the coronavirus pandemic - The Guardian [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Heres whos most at risk from the novel coronavirus - The Verge [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Closing Down the Schools Over Coronavirus - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- The U.S. Economy Cant Withstand the Coronavirus by Itself - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- U.S. Lags in Coronavirus Testing After Slow Response to Outbreak - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- U.K. Steps Up Coronavirus Prevention, But Its Hospitals Have Already Been Strained - NPR [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus panic is clearing out grocery stores; heres how workers are handling it - Vox.com [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Tracking the Coronavirus: How Crowded Asian Cities Tackled an Epidemic - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus Treatment: Hundreds of Scientists Scramble to Find One - The New York Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus cases have dropped sharply in South Korea. What's the secret to its success? - Science Magazine [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Facebook was marking legitimate news articles about the coronavirus as spam due to a software bug - The Verge [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- The Single Most Important Lesson From the 1918 Influenza - The New York Times [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- How to Protect Older People From the Coronavirus - The New York Times [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Coronavirus Is Killing Iranians. So Are Trump's Brutal Sanctions. - The Intercept [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Is there a cure for coronavirus? Why Covid-19 is so hard to treat - Vox.com [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Coronavirus: The math behind why we need social distancing, starting right now - Vox.com [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Europeans Erect Borders Against Coronavirus, but the Enemy Is Already Within - The New York Times [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Some of the last people on earth to hear about the coronavirus pandemic are going to be told on live TV - CNN [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Why the US is still struggling to test for the coronavirus - The Verge [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- The Coronavirus Is Here to Stay, So What Happens Next? - The New York Times [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Coronavirus in the U.S. - The New York Times [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Watch the Footprint of Coronavirus Spread Across Countries - The New York Times [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Coronavirus Briefing: What Happened Today - The New York Times [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Why the Covid-19 coronavirus is worse than the flu, in one chart - Vox.com [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Fact-Checking 5 Trump Administration Claims On The Coronavirus Pandemic - NPR [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Trump has scoreboard obsession. It hasnt worked with coronavirus - POLITICO [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Here's What Is In The 'Families First' Coronavirus Aid Package Trump Approved - NPR [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Young Adults Come to Grips With Coronavirus Health Risks - The New York Times [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Which Country Has Flattened the Curve for the Coronavirus? - The New York Times [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]