Nairobi, Kenya. Photo by Amani Nation via Unsplash.
By Naomi Frim-Abrams
On March 20, 2024, the Spring 2024 Human Capital Initiative Research Seminar Series hosted Elisa Maffioli, Assistant Professor of Health Management and Policy at the University of Michigan, to discuss her forthcoming study on the effect of social influence on vaccination behavior during COVID-19 in Kenya. The study evaluates a campaign where healthcare providers would visit homes and invite adults to be vaccinated at a site nearby, randomizing the announcement of the visit ahead of time.
COVID-19 vaccines are a vital public health intervention, but are not yet widespread globally, especially in the study area of Kenya. At the time of the study, in Summer 2022, there were 337,000 confirmed cases and 5,670 deaths from COVID-19 in Kenya, and 56 percent of the study sample population had never received a dose of a COVID-19 vaccine.
There are positive externalities to vaccines, and social influence can play a role in vaccine uptake. Maffioli and her research partners focused their study on two research questions: Can convenient access and invitations increase vaccination uptake, and does social influence promote vaccination?
The literature review examined supply and demand barriers to vaccine uptake, as well as the role of social pressure with a specific focus on the influence of healthcare providers. Prior research explored obstacles such as vaccine hesitancy and access; Maffiolis project builds on these ideas by providing both convenience of vaccination and personal invitations through healthcare workers.
Elisa and her fellow researchers decided to follow the Kenyan governments footsteps and mimicked their national COVID-19 vaccine deployment campaign. The researchers tried to address issues of both supply (setting up local vaccination sites) and demand (nudges by sending healthcare workers door-to-door) to improve vaccine uptake. They utilized a one-day vaccination campaign intervention to see the effects of the healthcare workers home visits more clearly, as the researchers could control for the spread of information and make sure that the campaign was being promoted by the healthcare workers alone, rather than news spreading through other community members. Researchers met with village elders to determine ideal sites for vaccinations that were public and identifiable such as churches, schools and community meeting spaces. The sample included randomly selected residents within a 15-minute walking radius of these sites.
The treatment used in this study, whether a healthcare workers visits were announced or unannounced, was randomized, and participants were not aware of which group they were part. Participants in the announced group were informed that a healthcare worker would visit their home within 30 minutes to ask if they wanted to receive a COVID-19 vaccine at the nearby site. Participants in the unannounced group received the health worker visit without being informed ahead of time.
Overall, the authors found an increase in dose uptake at the day of the campaign, and the effects were consistent after three months since the intervention. However, they found no evidence of social pressure by healthcare workers: those in the announced group were instead more likely to go and get vaccinated. Maffioli also discussed cost-effectiveness and policy implications. The researchers calculated that the marginal cost per marginal dose of their intervention, based on their data on recorded costs and the number of doses, was $41.76; for context, the most similar study on COVID-19 vaccinations in Sierra Leone estimated the implementation cost to be $33 per additional person vaccinated. In terms of policy, she spoke to the need to test alternative approaches to find even more cost-effective strategies, such as training community health volunteers or using alternative public transportation.
Throughout the presentation, the audience raised various questions about both the study elements and results. Maffioli first addressed comments as to whether historically there has been backlash against vaccination campaigns in Kenya, and if there is mistrust of medical personnel; she responded that there are actually high levels of trust in medical interventions, however, this was not entirely relevant to her research, as her team was addressing social pressure in uptake through the announced treatment. Others inquired about the privacy of the healthcare worker visit, and whether news of the intervention spread through community members overhearing or seeing the healthcare worker. She acknowledged that this was a strong point of feedback for the study, and they had not asked the healthcare workers to record whether they noticed others unintentionally witnessing their interactions with the participant. In terms of study design, an audience member asked about the randomization of the vaccination sites, as the locations were non-randomized and chosen after discussions with community elders.
Maffiolis research speaks to the health challenges of today, examining how an interdisciplinary approach can aid understanding of social barriers to health interventions. She commented in her conclusion that the delivery and acceptance of new vaccines should be a top global priority. A mode of vaccine delivery, such as the one explored in the study, that addresses barriers to vaccine supply and demand, and receives no backlash if provided by healthcare workers, remains a cost-effective strategy to increase vaccinations.
*
Posted3 days ago on Thursday, March 28th, 2024
Continued here:
- Biohackers Are on a Secret Hunt for the Coronavirus Vaccine - Reason [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Can synthetic biology protect us from coronavirus? And the next one? - Big Think [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- When will there be a coronavirus vaccine and who will get it first? - Yahoo News [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- These nine companies are working on coronavirus treatments or vaccines heres where things stand - MarketWatch [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Vaccine At Least a Year Away, But Treatment Could Be Here in Months - Newsweek [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Drug and Vaccine Studies Are Recruiting Their First Volunteers - TIME [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Brexit means coronavirus vaccine will be slower to reach the UK - The Guardian [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- First patient injected in trial of coronavirus vaccine - WCVB Boston [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- A coronavirus vaccine is in the making But you may have to check your pockets first - Duke Chronicle [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus vaccines and treatment: Everything you need to know - CNET [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus outbreak: How much testing should we do, and where are we on developing a vaccine? - Economic Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus Vaccines Precision Vaccinations [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- How Long Will It Take to Develop a Vaccine for Coronavirus? [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- California lab says it discovered coronavirus vaccine in 3 hours [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus outbreak in Wuhan, China: Vaccine may be ready in ... [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Everything You Need to Know About Canine Coronavirus Vaccine [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- CSU Researchers Are Working Full-Bore On The Mysteries Of Coronavirus And A Vaccine - Colorado Public Radio [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- How soon will we have a coronavirus vaccine? The race against covid-19 - New Scientist [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Coronavirus trial vaccine participant says he wants to help the world - CNN [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Daily briefing: The five questions that scientists hunting a coronavirus vaccine must answer - Nature.com [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Baltimore scientists to work on third experimental coronavirus vaccine - Baltimore Sun [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- The coronavirus could kill millions of Americans: 'Do the math,' immunization specialist says - CNBC [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- We're still in the early days of coronavirus vaccine research - Axios [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Inoculating the Coronavirus Vaccine Against the Profit Pandemic - The New Republic [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Wanted: People Willing to Get Sick to Find Coronavirus Vaccine - The Wall Street Journal [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Coronavirus vaccine trial, Mars rover delay and a boost for UK science - Nature.com [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Thousands of scientists are racing to find a vaccine for coronavirus. 41 possibilities are in the works. - The Californian [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- 'I Wanted To Do Something,' Says Mother Of 2 Who Is First To Test Coronavirus Vaccine - NPR [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Vaccine Trials To Fight Coronavirus Offer Hope, Could Be Harbinger Of New Technology - Outlook India [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- Image of COVID-19 test kit shared as newly developed 'coronavirus vaccine' by Roche - Alt News [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- A coronavirus vaccine is the only thing that can make life 'perfectly normal' again, former FDA commissioner says - The Week [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- Johnson & Johnson CEO on potential coronavirus vaccine: 'I think we'll have important data by the end of the year' - Fox News [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- As the First Coronavirus Vaccine Human Trials Begin, Manufacturer Is Already Preparing to Scale Production to Millions - TIME [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- A coronavirus vaccine is the only thing that can make life 'perfectly normal' again, former FDA commissioner says - Yahoo News [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- This Vaccine Could Save Health Care Workers From the Coronavirus - Foreign Policy [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Coronavirus vaccine must be affordable and accessible - The Conversation CA [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Over 100 drugs are in testing in the race to treat coronavirus - Axios [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- This is when the first coronavirus drugs might actually be available - BGR [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Another Day, Another Meme to Debunk: Vaccines for the Bovine Coronavirus Will Not Cure COVID-19 - Mother Jones [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- A Coronavirus Vaccine Could Be the First That Outwits Nature - Singularity Hub [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Coronavirus treatment other than vaccines may be available soon - The Jerusalem Post [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Coronavirus: Vaccine hopes given boost as researcher says virus not mutating - The Independent [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Coronavirus Vaccine Is Critical, The Infection Could Become Seasonal, Researchers Warn - NDTV News [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- A coronavirus vaccine from Virginia? These researchers are working on it. - The Virginian-Pilot - The Virginian-Pilot [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Scientists, under pressure, try to balance speed and safety on coronavirus vaccine research - NBCNews.com [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Should scientists infect healthy people with the coronavirus to test vaccines? - Nature.com [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Coronavirus Vaccines May Not Work for the Elderlyand This Lab Aims to Change That - Scientific American [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Vaccine Development Is Risky Business. Biotechs Are Tackling The Coronavirus, Anyway - WBUR [Last Updated On: March 29th, 2020] [Originally Added On: March 29th, 2020]
- Coronavirus vaccine: how soon will we have one? - World Economic Forum [Last Updated On: March 29th, 2020] [Originally Added On: March 29th, 2020]
- USC Working on Coronavirus Vaccine, Researchers Announce - NBC Southern California [Last Updated On: March 29th, 2020] [Originally Added On: March 29th, 2020]
- Tracking the development of coronavirus treatments - NBC News [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- In the fight against coronavirus, antivirals are as important as a vaccine. Here's where the science is up to - The Conversation AU [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- Johnson & Johnson Says It Could Have Coronavirus Vaccine Ready by Early 2021 - The Daily Beast [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- Coronavirus: when will the vaccine be ready? - AS South Africa [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- A Coronavirus Vaccine Is Coming, And It Will Work - City Journal [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- With record-setting speed, vaccinemakers take their first shots at the new coronavirus - Science Magazine [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- CDC: Coronavirus Vaccine Will Be Ready for Refusal By Anti-Vaxxers By 2021 - MedPage Today [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- The race to find a coronavirus treatment has one major obstacle: big pharma - The Guardian [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- Why A Coronavirus Vaccine May Be Years Away - The National Interest [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- The race is on for coronavirus vaccines and treatments: current R&D status - The Pharma Letter [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- Tests of potential coronavirus vaccine spur growth of virus-fighting antibodies - USA TODAY [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- A 100-yr-old vaccine is being tested against the new coronavirus. Can it work? - Economic Times [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Coronavirus Live Updates: Boris Johnson Moved to Intensive Care and the U.S. Death Toll Surpasses 10,000 - The New York Times [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- When will a coronavirus shot be ready? A look at the vaccine race. - WRAL.com [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Hulk Hogan on coronavirus: Maybe we dont need a vaccine - Tampa Bay Times [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- White House advisor Fauci says coronavirus vaccine trial is on target and will be 'ultimate game changer' - CNBC [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Coronavirus vaccine will take time, so researchers are hunting for and finding promising new COVID-19 tre - OregonLive [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Chester County to begin testing for coronavirus antibodies; British prime minister moved to intensive care - The Philadelphia Inquirer [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- MAP: Where coronavirus treatments and vaccines are being tested on patients in the US - Business Insider - Business Insider [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Coronavirus pandemic: Why it takes so long to make a vaccine - Business Today [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- A vaccine for coronavirus is the goal, but what does it take to get there? - ABC News [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- Trump says there's light at the end of the tunnel with coronavirus vaccine and treatment research - CNBC [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- Russia Ready to Start Testing Coronavirus Vaccines on Humans in June - The Moscow Times [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- Why a coronavirus vaccine takes over a year to produce and why that is incredibly fast - World Economic Forum [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- Pandemic expert calls for manufacturing coronavirus vaccines before they're proven to work - The Week [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- More Coronavirus Vaccine Efforts Move Toward Human Trials - The New York Times [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- A coronavirus vaccine is being developed in record time. But don't expect that technology to speed up flu vaccines yet. - USA TODAY [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- A New Front for Nationalism: The Global Battle Against a Virus - The New York Times [Last Updated On: April 10th, 2020] [Originally Added On: April 10th, 2020]
- Here's how your body gains immunity to coronavirus - The Guardian [Last Updated On: April 10th, 2020] [Originally Added On: April 10th, 2020]
- Pfizer aims to create coronavirus vaccine by end of 2020 - MLive.com [Last Updated On: April 10th, 2020] [Originally Added On: April 10th, 2020]