From bad to worse: How avian flu must change to trigger a human …

Whatever path the virus hits upon, H5N1 needs an altered PB2 to become a human pathogen. Think of evolving into a pandemic virus as a ladder that H5N1 has to climb, Beer says. Then this is the first step. It seems an easy step. H5N1 has managed it several times already in the current avian flu virus outbreak.

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From bad to worse: How avian flu must change to trigger a human ...

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