England Offers Ample Access to UTI Vaccines – Precision Vaccinations

London (Precision Vaccinations News)

The United Kingdom's NHS recently updated its urinary tract infection (UTI) webpage to explain that some people may experience persistent UTI symptoms, and current urine tests may not detect chronic infections caused by bacteria embedded in the bladder lining.

Chronic UTIs, also known as recurrent UTIs (rUTIs), are typically treated with antibiotics. The NHS advises patients to ask their GP to refer them to a specialist if they experience rUTIs.

A recent study in England revealed that a novel oral spray vaccine could potentially prevent rUTIs for years. Researchers at the Royal Berkshire Hospital conducted a significant clinical trial using the Uromune (MV140) vaccine.

Nine years after treatment, 54% of participants in the study reported the vaccine's continued efficacy without significant side effects.

In previous clinical research, Uromuneinducedimmune responses systemicallyand in thegenitourinarytract, especially the bladder's innate immune system.

This multi-dose vaccinecontainsfourwhole-cell inactivated bacteria:Escherichia coli,Klebsiellapneumoniae,Proteus vulgaris,andEnterococcus faecalis.UropathogenicEscherichia coli accounts for themajorityof community-acquired UTIs.

Recently, access to Uromune in Englandhas expanded topatients who have been treated in secondary care before referral and have failed standard treatment protocols for uncomplicated urinary tract infections, overactive bladder, and chronic bladder pain.

These vaccine providers include:

London Urologica operates from The London Clinic, a charitable hospital in central London.At The London Clinic,internationalconsultants with teams of health professionalsspecializein the care and treatment of complex medical conditions.

The Lower Urinary Tract Symptoms Service is a specialist for adult patients with complex chronic or rUTIs. Specialists in this tertiary clinic adhere to protocols requiringstrict clinical governance.

The Urology Partnership (The Reading Urology Partnership) comprisesconsultants, each with a particular field of excellence. Allconsultants hold substantive appointments at theRoyal Berkshire NHS Foundation Trust Hospitalin Reading, Berkshire.

For rUTI patients willing to travel, the Uromune vaccine may be offered via Expanded Access Programs. Theseprograms arefor individuals for whom antibiotic therapy has failed, antibiotic-induced adverse reactions, and increasing antibiotic resistance.

Uromune is offered inthe DominicanRepublic, Singapore, and other countries. Vaccine appointments can be requested at Vax-Before-Travel.

However, Uromune is unavailable in the United States, but UTI vaccineclinical trialsare active in 2024.

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England Offers Ample Access to UTI Vaccines - Precision Vaccinations

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