Dengue Vaccines Harder to Find in 2024 Precision Vaccinations News – Precision Vaccinations

Atlanta (Precision Vaccinations News)

During the U.S. Centers for Disease Control and Prevention (CDC) vaccine committee meeting this afternoon, it will bementioned that finding a dengue vaccine in 2024 poses a challenge for international travelers.

At 5 PM ET on June 26, 2024, the CDC's Advisory Committee on Immunization Practices (ACIP) meeting is scheduled toreview two presentations that reveal the leading dengue vaccines are unavailable this year to U.S.-based international travelers.

This is unfortunate news for people planning to visit any of the 90 countries reporting dengue cases in 2024.

Furthermore, the CDC says dengue is endemic in sixU.S. territories and freely associated states. This health risk includes Puerto Rico and southeast Florida, where the CDC has reported travel-related and locally acquireddengue cases in 2024.

Dengvaxia, the only U.S. FDA-approved dengue vaccine,is discontinued due to low demand. According to Sanofi, the vaccine's producer, this decision was not based on quality, safety, or efficacy concerns.

Since Dengvaxia vaccination began in Puerto Rico, 145 peoplehave been administered the vaccine, but only 32 have completed the third dose of the series.

Dengvaxia will continue to be distributed globally through public and private markets, including Puerto Rico, where the ACIP currently recommends ituntil the product expires. The last doses of Dengvaxiawill expire at the end of August 2026.

Over the past year, Japan's Takeda's Qdenga vaccinebecame the market leader, quickly selling out its production capability. In July 2023,Takeda voluntarily withdrew Qdengafrom FDA review, which means the vaccine is unavailable inthe U.S.

The good news is that various dengue vaccine candidates are conducting late-stage clinical trials in 2024, withaspirationsfor market authorizations later this year or in 2025.

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Dengue Vaccines Harder to Find in 2024 Precision Vaccinations News - Precision Vaccinations