Category: Vaccine

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Self-Administered Nasal Flu Shot Approval Under FDA Review – Precision Vaccinations

October 25, 2023

Wilmington (Precision Vaccinations News)

For the first time, an influenza vaccine sprayed into the nose that protects peopleagainst the seasonal fluhas been accepted for review by the U.S. Food and Drug Administration (FDA).

If approved by the FDA, FLUMIST QUADRIVALENT will be the first live nasal influenzavaccine available to be self-administered by eligible patients or administered by caregivers.

AstraZeneca today announced itsSupplemental Biologics License Application (sBLA) for the approval of a self- or caregiver-administered option for FLUMIST QUADRIVALENT (Influenza Vaccine Live, Intranasal), a needle-free nasal spray,

The sBLA is supported by a usability study that confirmed that adultsover 18 could self-administer or administer FLUMIST QUADRIVALENT to eligible patients 2-49 years of age when given instructions for use without any additional guidance.

The FDA's Prescription Drug User Fee Act date is expected during the first quarter of 2024. If approved, FLUMIST QUADRIVALENT is anticipated to be available for self-administration in the U.S. for the 2024/2025 flu season.

This means people could be able to get a flu vaccination while attheir homes next year.

Nasal vaccines bypassTrypanophobia, an overlooked condition that affects virtually all medical procedures.Estimates show that as many as 2 in 3 children and 1 in 4 adults have intense fears around needles.

Ravi Jhaveri, MD, Division Head, Infectious Disease; Virginia H. Rogers Professor in Infectious Diseases, Professor of Pediatrics, Northwestern University School of Medicine, commented in a press release on October 24, 2023, ....." The ability for individuals and parents to choose where to administer an injection-free flu vaccine could help increase access and, subsequently, vaccination rates, and greatly benefit those most impacted by this serious and contagious respiratory illness."

FLUMIST QUADRIVALENT is aleady an FDA-approved influenza vaccine. It is sprayed into the nose and has extensive data demonstrating comparable effectiveness and acceptable safety relative to other flu vaccines.

The most common side effects are runny or stuffy nose, sore throat, and fever over 100F.

On September 5, 2023,AstraZenecaannounced FLUMIST QUADRIVALENT nasal vaccinedoses wereavailable in the U.S.

You should not get FLUMIST QUADRIVALENT if you have a severe allergy to eggs or any inactive ingredient in the vaccine, have ever had alife-threateningreaction to influenza vaccinations, or are 2 through 17 takingmedicines containingaspirin. Childrenor adolescents should not be given aspirin for four weeks after getting FLUMIST QUADRIVALENT unless their healthcare provider tells them otherwise.

And informyour healthcare provider if you or your child are currently wheezing; have a history of wheezing if under five years old; have had Guillain-Barr syndrome; have a weakened immune system or live with someone who has a severely weakened immune system; have problems with your heart, kidneys, or lungs; have diabetes; are pregnant or nursing; or are taking a medication used to treat influenza.

Like most flu shots, FLUMIST QUADRIVALENT may not prevent influenza in everyone vaccinated. FLUMIST is currently available in the U.S. and the United Kingdom.

As of October 14, 2023,136.94 million flu shots had been distributed in the U.S. for the 2023-2024 flu season.

Originally posted here:

Self-Administered Nasal Flu Shot Approval Under FDA Review - Precision Vaccinations

Hope rises that a vaccine can shield people with HIV from a deadly threat – Nature.com

October 25, 2023

Monkeys with a form of HIV can gain immunity to tuberculosis after the century-old BCG vaccine is delivered into their bloodstream1.

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Nature 622, 673 (2023)

doi: https://doi.org/10.1038/d41586-023-03220-1

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Hope rises that a vaccine can shield people with HIV from a deadly threat - Nature.com

COVID-19 Vaccine Protects Against the Corona Virus in Patients with Celiac Disease – Channel3000.com – WISC-TV3

October 25, 2023

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COVID-19 Vaccine Protects Against the Corona Virus in Patients with Celiac Disease - Channel3000.com - WISC-TV3

RFK Jr. spent years stoking fear and mistrust of vaccines. These people were hurt by his work – Yahoo News

October 25, 2023

When 12-year-old Braden Fahey collapsed during football practice and died, it was just the beginning of his parents nightmare.

Deep in their grief a few months later, Gina and Padrig Fahey received news that shocked them to their core: A favorite photo of their beloved son was plastered on the cover of a book that falsely argues COVID-19 vaccines caused a spike of sudden deaths among healthy young people.

The book, called Cause Unknown, was co-published by an anti-vaccine group led by Robert F. Kennedy Jr., President John F. Kennedys nephew, who is now running for president. Kennedy wrote the foreword and promoted the book, tweeting that it details data showing COVID shots are a crime against humanity.

The Faheys couldnt understand how Bradens face appeared on the books cover, or why his name appeared inside it.

Braden never received the vaccine. His death in August 2022 was due to a malformed blood vessel in his brain. No one ever contacted them to ask about their sons death, or for permission to use the photo. No one asked to confirm the date of his death which the book misdated by a year. When the Faheys and residents of their town in California tried to contact the publisher and author to get Braden and his picture taken out of the book, no one responded.

We reached out in every way possible, Gina Fahey told The Associated Press in an emotional interview. We waited months and months to hear back, and nothing.

How could a member of one of the most influential political dynasties in American history be involved in such a shoddy, irresponsible project, the Faheys wondered?

Bradens story is just one example of how Kennedy, son of the late Sen. Robert F. Kennedy, has used his famous name to disseminate false information about vaccines and other topics in a time when spreading conspiracy theories has become a powerful way to grow a constituency. An AP examination of his work and its impact found Kennedy has earned money, fame and political clout while leaving people like the Faheys suffering.

Now, Kennedys decision to drop his Democratic bid for president and run as an independent gives him a new spotlight in an election thats currently heading toward a rematch between President Joe Biden and former President Donald Trump. Theres concern in both parties that he could emerge as a spoiler who could affect the outcome of the campaign in unexpected ways. And at a time when Republicans in the 2024 race also are sowing doubt about vaccine effectiveness, it threatens to further promote harmful misinformation that already has cost lives.

One mom told AP about how she had delayed important care for her child because she believed Kennedys vaccine falsehoods. A former elected leader described being harassed by Kennedys followers. Doctors and nurses recounted how his work has hurt people in the U.S. and abroad.

Kennedys campaign did not respond to several emails seeking comment for this article, but after AP contacted Kennedy and others involved in the book last week, the president of Skyhorse Publishing, which co-published it, texted the Faheys, offering to talk. Gina Fahey told AP she felt he reached out only after it became clear the situation could harm his reputation.

Theres still that lack of compassion that was always there from the beginning, she said, adding that she is hesitant to engage with them now because she doesn't trust their intentions. Its only now that theyre reaching out, days prior to knowing this story is going to be released.

Bradens parents have read vicious comments from people who falsely blame vaccines for their son's death. They say seeing Bradens memory being misrepresented by Kennedy and others has been deeply painful.

When you barely feel like you can even come up for air, you just get smacked back down again by this, Gina Fahey said.

Its very manipulative. And you know, hes making money off of our tragedies, she said, adding, How could you want somebody running our country that operates like that?

___

Many years before anti-vaccine activists exploited the pandemic to bring their ideas to the American mainstream, Kennedy, an environmental lawyer, was among the most influential spreaders of fear and distrust around vaccines. He has long advanced the debunked idea that vaccines cause autism. He has said vaccines had caused a holocaust, and has traveled the world spreading false information about the pandemic.

In recent years, Kennedy has used his name and rhetorical skills to build his anti-vaccine group, Childrens Health Defense, or CHD, into an influential force that spreads false and misleading information. An AP investigation previously revealed how Kennedy had capitalized on the pandemic to build CHD into a multimillion-dollar misinformation engine.

One of the ways Kennedy and CHD have made money is through the sale of books. Kennedys longtime publisher, Skyhorse, joined with CHD to create a book series that has published titles including Vax-Unvax, Profiles of the Vaccine Injured, and the book that included Braden Fahey, Cause Unknown.

Written by Edward Dowd, a former executive at BlackRock, that book is built on the false premise that sudden deaths of young, healthy people are spiking. Experts say these rare medical emergencies are not new and have not become more prevalent.

"We are just not seeing anything that suggests that, said Dr. Matthew Martinez, of Atlantic Health System in Morristown Medical Center, who researches cardiac events among professional athletes.

The AP found dozens of individuals included in the book died of known causes not related to vaccines, including suicide, choking while intoxicated, overdose and allergic reaction. One person died in 2019.

AP asked Kennedys campaign, CHD, Dowd and Skyhorse president Tony Lyons several questions about the book, including why they chose to feature Braden, why they didnt speak to his family first and what steps they took to fact check.

The only person to respond was Lyons, who also co-chairs the Kennedy Super PAC American Values 2024.

In emails, Lyons did not address why Braden specifically was chosen for the cover but defended his inclusion by saying that news stories and his obituary did not mention his cause of death.

Hundreds of deaths are cited in the book, though Lyons said it only attributes nine of them to the vaccine. Lyons said Braden's death and others are never explicitly attributed to the vaccine, and that the book explores many possible reasons for deaths that have appeared in headlines since 2021.

Still, the book several times refers to its thesis" that mass administration of COVID-19 vaccines caused a spike in deaths. Bradens parents said his appearance in the context of the book implies he died of the vaccine, putting his death in a false light.

Lyons said he was unaware of the Faheys efforts to contact his company and asked AP to share with them his contact information. He said he would make some corrections in future editions, including to Braden's date of death, but said they were studying whether to remove him from the book or the cover.

Lyons told the AP that Children's Health Defense has a publishing deal with Skyhorse, though he would not say how much money CHD has received through it.

Kennedy also has a consulting deal with Skyhorse that personally paid him $125,000 since August 2022 for scouting out books for the company, according to a financial disclosure he filed. Lyons said that deal has so far resulted in 27 books of different genres including childrens books, mysteries and cookbooks, but declined to name them.

Lyons also praised Kennedy's record of environmental work, such as protecting New Yorks Hudson River, and other work he's done to take on powerful corporate interests and what Kennedy sees as government corruption. Those are also topics Kennedy has focused on during his presidential campaign.

The platform Kennedy built for himself has an impact. In a study of verified Twitter accounts from 2021, researchers Francesco Pierri, Matthew DeVerna and others working with Indiana Universitys Observatory on Social Media found Kennedys personal Twitter account was the top superspreader of vaccine misinformation on Twitter, responsible for 13 percent of all reshares of misinformation, more than three times the second most-retweeted account.

The messages Kennedy shares have convinced a significant slice of the public, some of whom attend his campaign events proudly wearing pins with crossed-out syringes or repeating Kennedys talking points about vaccine ingredients.

Kennedys anti-vaccine organization has a lawsuit pending against a number of news organizations, among them The Associated Press, accusing them of violating antitrust laws by taking action to identify misinformation, including about COVID-19 and COVID-19 vaccines. Kennedy took leave from the group when he announced his run for president but is listed as one of its attorneys in the lawsuit.

___

Many people have staked their lives and the lives of their families on the views espoused by Kennedy and others who oppose vaccines.

The AP spoke to mothers who once identified as anti-vaccine and counted themselves among Kennedys most devoted followers.

I thought he was heroic, because he was saying the things publicly that other people were too afraid to say, said Lydia Greene.

Greene, who lives in the Canadian province of Alberta, declined all vaccines for her son after buying into the claims by Kennedy and other anti-vaccine gurus that vaccines cause autism. When her son started to show signs of autism, Greene discounted it out of hand.

I couldnt even see his autism because in the anti-vax movement, autism is the worst outcome that can happen to a child. And when they talk about their vaccinated autistic kids, its often with a tone of resentment and how they talk about how their life is ruined, their marriage is ruined, and its just this kid is damaged, Greene said. And so when my son was different, I couldnt see that stuff about him.

She said she did not recognize his condition until she came out of the rabbit hole of anti-vax.

I realized I had wasted so much valuable time where he should have been in occupational therapy, speech therapy, evidence-based therapy for autism, Greene said.

Kennedys Childrens Health Defense produces articles, newsletters, books, podcasts, even TV shows on its own CHD.TV. Greene said those articles often validate anxious parents fears no matter how irrational while making them feel like someone powerful is listening.

Today, Greene believes the group exploited her.

Thats what CHD does, Greene said. They find parents when theyre vulnerable. And hack into that.

Because of his national profile, Kennedys work has ripple effects beyond the most devoted anti-vaccine activists.

Medical professionals told the AP that vaccine disinformation spread by Kennedy and other influencers makes the patients they serve wary about lifesaving vaccinations.

Sharon Goldfarb, is a family nurse practitioner in Berkeley, California, who spent the worst of the pandemic caring for people on societys margins: people with no homes; people who were living in the country illegally; people with serious mental health needs. She has seen firsthand the consequences of vaccine misinformation and refusal.

Its disturbing because he has a huge family name, Goldfarb said. When youre a trusted public figure and you have a trusted family name, you have to answer to a higher authority. I just dont get it."

Dr. Todd Wolynn, a Pittsburgh pediatrician who works to clarify the facts about vaccines on social media, said despite Kennedys lack of clinical experience, he has an outsized influence on his followers.

He uses a very big platform to amplify disinformation that leads people down a path to make a decision thats not evidence based, Wolynn said. And as a result, it puts their own lives, the lives of their children, the lives of their family, in harms way.

Though Kennedy did not respond for this story, he has long said that he is not anti-vaccine, and only wants vaccines to be rigorously tested. The Centers for Disease Control and Prevention explains that vaccines undergo thorough testing before they are authorized or approved in the U.S. and they are monitored for safety after they are introduced to the public.

COVID-19 vaccines were initially developed under the Trump administration, through the program Operation Warp Speed. But what his Republican-led administration viewed at the time as a point of pride has since become a topic of criticism in Republican circles, including among GOP presidential candidates who have expressed skepticism about the immunizations.

The Republican candidate and biotech entrepreneur Vivek Ramaswamy said in a July podcast interview that if hed had the facts he would not have gotten vaccinated against COVID-19. The administration of fellow GOP candidate Florida Gov. Ron DeSantis has broken with CDC guidance to advise Floridians under 65 not to get the latest COVID-19 booster.

That kind of rhetoric, along with the conspiracy beliefs that Kennedy has shared about other subjects, like 5G, can impact the smooth running of societies, said Daniel Jolley, a University of Nottingham social psychology professor, who has published several papers on conspiracy thinking and its impacts.

While skepticism is important, proper evaluation of the evidence is key, Jolley said. Anyone pushing conspiracy theories while running for president makes the theories seem normal.

Its that kind of rhetoric that I think is really damaging, Jolley said. You worry when you think about the next pandemic or the next event or the next issue thats going to come our way.

Jolley wonders: Will people listen to doctors or experts next time?

___

Kennedy's role in legitimizing anti-vaccine activism has not been limited to the U.S. Perhaps the most well-known example was in 2019 on the Pacific island nation of Samoa.

That year, dozens of children died of measles. Many factors led to the wave of deaths, including medical mistakes and poor decisions by government authorities. But people involved in the response who spoke to AP said Kennedy and the anti-vaccine activists he supported made things worse.

In June 2019, Kennedy and his wife, the actress Cheryl Hines, visited Samoa, a trip Kennedy later wrote was arranged by Edwin Tamasese, a Samoan local anti-vaccine influencer.

Vaccine rates had plummeted after two children died in 2018 from a measles vaccine that a nurse had incorrectly mixed with a muscle relaxant. The government suspended the vaccine program for months. By the time Kennedy arrived, health authorities were trying to get back on track.

He was treated as a distinguished guest, traveling in a government vehicle, meeting with the prime minister and, according to Kennedy, many health officials and the health minister.

He also met with anti-vaccine activists, including Tamasese and another well-known influencer, Taylor Winterstein, who posted a photograph of herself and Kennedy on her Instagram.

The past few days have been profoundly monumental for me, my family and for this movement to date, she wrote, adding hashtags including #investigatebeforeyouvaccinate.

A few months later, a measles epidemic broke out in Samoa, killing 83 people, mostly infants and children in a population of about 200,000.

Public health officials said at the time that anti-vaccine misinformation had made the nation vulnerable.

The crisis of low vaccination rates and skepticism created an environment that was ripe for the picking for someone like RFK to come in and in assist with the promotion of those views, said Helen Petousis-Harris, a vaccinologist from New Zealand who worked on the effort to build back trust in the measles vaccine in Samoa.

Petousis-Harris recalled that local and regional anti-vaccine activists took their cues from Kennedy, whom she said sits at the top of the food chain as a disinformation source.

They amplified the fear and mistrust, which resulted in the amplification of the epidemic and an increased number of children dying. Children were being brought for care too late, she said.

Kennedys campaign did not respond to emails seeking comment about Samoa, though he says on his campaign website that he had no role in the outbreak. He also said in an interview for a forthcoming documentary, Shot in the Arm, that he bears no responsibility for the outcome.

I had nothing to do with people not vaccinating in Samoa. I never told anybody not to vaccinate. I didnt, you know, go there for any reason to do with that.

But people who worked on the Samoan measles response told AP the credibility he gave to anti-vaccine forces when he met with them had an impact.

Moelagi Leilani Jackson, a Samoan nurse who worked on the vaccination campaign to stem the scourge of measles, said she remembered that after Kennedys visit, the anti-vaccine influencers got louder.

I feel like they felt they had the support of Kennedy. But I also think that Kennedy was very well, he came in and he left, she recalled. And other people picked up the pieces.

___

A few weeks after his trip to Samoa, Kennedy appeared in Sacramento, California, where lawmakers were debating a bill to make it more difficult to get a vaccine exemption. The bill was sponsored by Democratic state Sen. Richard Pan, a pediatrician.

As a crowd gathered outside the capitol, Kennedy stood to speak. Two large posters behind him featured Pans image, with the word LIAR stamped across his face in blood-red paint. Pan told AP he felt the staging was intended to incite the crowd against him.

So hes rallying to have people attack me, essentially, personally, said Pan, who is no longer in office.

Within months, one anti-vaccine extremist assaulted Pan, streaming it live on Facebook. Another threw blood at Pan and other lawmakers.

Kennedy has repeatedly brought up the Holocaust when discussing vaccines and public health mandates, comparisons that Pan said amount to an indirect call to violence against health advocates.

Who creates an atmosphere where they think whats appropriate is to actually physically assault a legislator? Its people like Robert F. Kennedy Jr. Pan said.

Pan said its one of many instances when Kennedy has whipped people up against public health advocates. Kennedy also wrote a bestselling book attacking infectious disease expert and former top government scientist Dr. Anthony Fauci, who has received death threats.

Those attacks have prompted criticism from Kennedys sister Kerry Kennedy, who invoked the Kennedy family history of political violence their father and uncle were both assassinated when she told the AP in 2021: Attacking doctors and scientists is irresponsible because many have received death threats. This can deter people from those professions. Our family knows that a death threat should be taken seriously.

Kerry Kennedy and three other siblings on Oct. 9 issued a statement denouncing Kennedys independent candidacy, calling it dangerous and perilous to the country.

Pan said that Kennedys rhetoric, which often demonizes scientists and health care professionals, is part of a strategy to intimidate and silence them.

When you call something a holocaust, it is incitement to violence, Pan said.

The real consequence of Robert F. Kennedy Jr. is we have dead children, and we have people who are in good faith doing their best to try to protect people, including children, who are basically being threatened and even assaulted because of his rhetoric and his lies, said Pan, who is now running for mayor of Sacramento, a nonpartisan position. That harms America.

___

Associated Press video journalist Terry Chea contributed to this report.

___

The Associated Press receives support from several private foundations to enhance its explanatory coverage of elections and democracy. See more about APs democracy initiative here. The AP is solely responsible for all content.

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RFK Jr. spent years stoking fear and mistrust of vaccines. These people were hurt by his work - Yahoo News

The Latest on COVID-19 Subvariants and Vaccines – CleanLink

October 25, 2023

According to reporting from the U.S. Department of Health and Human Services, over seven million Americans have received the updated COVID-19 vaccine as of Oct. 11 intended to minimize or prevent the XBB1.5 Omicron subvariant. The updated single-frequency shots are available from BioNTech, Pfizer, or Moderna. Additional vaccines have available from Novavax as well during the week of Oct. 9, which are now accessible to millions of Americans, Reuters notes.

XBB1.5 is still prevalent and has been the primary subvariant affecting people over the majority of 2023, but has since been overtaken. Other variants are emerging as threats, including EG.5, which currently accounts for nearly a quarter of all cases across the United States.

Across all variants which includes the original SARS-CoV-2 virus nearly 7.6 millionAmericans had received and updated shot dating back to Sept. 28, 2022. Overall, the demand for COVID-19 vaccines has drastically dropped since its peak in 2021, with roughly 17 percent of the total U.S. population getting the vaccines. Current recommendations per U.S. public health officials are for everyone above the age of 6 months to receive a dosage. More information on the vaccines and their availability can be found here.

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The Latest on COVID-19 Subvariants and Vaccines - CleanLink

Parents Are Asked To Unite Against Killer Flu – Extra.ie

October 25, 2023

New research from the Irish Patients Association has revealed that four in ten parents hesitate to get their children the free winter flu vaccine.

Despite 1,274 children being hospitalised with the virus during the flu season last year, over a quarter of parents think the winter flu doesn't have serious consequences for their children.

Mayo GAA Star Aidan O'Shea, pharmacist Laura Dowling and Professor of Immunology Christine Loscher have joined forces with the IPA to launch the Flunited campaign, urging parents to protect their children from flu this winter.

The campaign hopes to emphasis the importance of children getting the vaccine this winter, asking both parents and guardians to unite with health professionals to combat the annual flu outbreak as a collective effort.

For young children sometimes the consequences of flu can be serious and can lead to problems such as pneumonia, bronchitis, and inflammation of the brain (encephalitis).

During the 2022/2023 flu season, a staggering 1,274 children were hospitalized with the virus. Over half of the parent surveyed knew that children were at risk of serious complications if they caught flu.

Despite these alarming statistics, recent research conducted by Empathy Research on behalf of IPA has revealed that over 4 in 10 parents (44%) hesitate to vaccinate their children against winter flu.

'Children are twice as likely to catch flu as adults,' says Professor of Immunology Christine Loscher . 'Children with complications may need hospital treatment. Some may need intensive care.

'In the past 10 years in Ireland, almost 5,000 children were admitted to hospital with complications of flu. Almost 200 children had treatment in intensive care and 40 children died. So it's key parents are aware of the risks.'

The children's flu vaccine, administered as a free nasal spray to of all children 2-12 and children aged 13-17 at high risk of flu, is accessible at local GPs, participating pharmacies, and, for the first time this year, in participating schools across the country. Ask your GP for details.

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Parents Are Asked To Unite Against Killer Flu - Extra.ie

Childrens winter flu campaign launched by Mayo GAA star and his Flunited team – Connaught Telegraph

October 25, 2023

Published: Tue 24 Oct 2023, 2:58 PM

New research from the Irish Patients' Association (IPA) reveals that four in 10 parents hesitate to get their children the free winter flu vaccine.

Despite 1,274 children being hospitalised with the virus during the flu season last year, over a quarter of parents perceive the winter flu as not having serious consequences for their children.

In response to this, Mayo and Breaffy GAA star Aidan O'Shea, pharmacist Laura Dowling and professor of immunology Christine Loscher have joined forces with the IPA to launch the 'Flunited' campaign, urging parents to protect their children from flu this winter.

Flunited (a portmanteau of 'flu' and 'united') emphasises the importance of the children's flu vaccine this winter, rallying parents and guardians to unite with the team to combat the annual flu outbreak as a collective effort.

The campaign aims to highlight that for young children, sometimes the consequences of flu can be serious and can lead to problems such as pneumonia, bronchitis and inflammation of the brain (encephalitis). So, driving awareness of these consequences and the free access they have to this vaccine is key.

The children's flu vaccine, administered as a free nasal spray to all children aged from two to 12 and children aged from 13 to 17 at high risk of flu, is accessible at local GPs, participating pharmacies and, for the first time this year, in participating schools across the country.

During the 2022/23 flu season, 1,274 children were hospitalized with the virus. Despite these statistics, recent research conducted by Empathy Research on behalf of IPA has revealed that over four in 10 parents (44%) hesitate to vaccinate their children against winter flu.

Professor Loscher commented: Children are twice as likely to catch flu as adults, and children with complications may need hospital treatment. Some may need intensive care.

In the past 10 years in Ireland, almost 5,000 children were admitted to hospital with complications of flu. Almost 200 children had treatment in intensive care and 40 children died. So its key parents are aware of the risks.

Speaking at the campaign launch, Aidan O'Shea said: As a dad, I know everyday life is disrupted when children are sick. This impacts not only their well-being but parents' work, routine and kids' education. We all have a responsibility to stop the spread. So don't let the flu take the field join a winning team!

Pharmacist Laura Dowling, who has amassed a large following on social media for her humorous, informative posts, reassured parents: The childrens flu vaccine is administered as a quick and virtually painless nasal spray in each nostril, taking less than six seconds and providing robust protection.

Stephen McMahon, Irish Patients' Association, strongly advocated for collective action. He said: Together we will guarantee a robust, flu-free season for schools and households throughout the nation.

The Flunited campaign seeks to empower parents and guardians with the knowledge and resources they need to safeguard their children and communities against the flu. More information is available from the HSE and Irish Patients' Association. This campaign is funded by AstraZeneca Ireland.

Published: Tue 24 Oct 2023, 2:58 PM

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Childrens winter flu campaign launched by Mayo GAA star and his Flunited team - Connaught Telegraph

Updated COVID-19 vaccines receive mixed support among health care professionals online – Healio

October 25, 2023

October 24, 2023

2 min read

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An analysis of online conversations among health care professionals on social media during September revealed mixed reactions toward newly updated messenger RNA COVID-19 vaccines.

Health care professionals (HCPs) were torn on the FDAs Sept. 11, 2023, approvals of Pfizer-BioNTech and Modernas updated booster vaccines.

Some cited the lack of a clinical emergency to justify the approvals, whereas others raised concerns around the possible side effects on some population groups. Others, however, were proponents of the booster vaccines, highlighting the severity of the disease and the importance of vaccinations to avoid hospitalization.

In addition to Moderna and Pfizers updated mRNA COVID-19 booster vaccines, the analysis showed two other spikes in online conversation among HCPs.

The FDAs Sept. 22 approval of Eli Lilly and Boehringer Ingelheims Jardiance (empagliflozin) drove an increase in mentions. The sodium-glucose cotransporter-2 inhibitor reduces the risk of sustained decline in estimated glomerular filtration rates and hospitalization in adults with chronic kidney disease. HCPs were nuanced in their opinions surrounding the approval, but despite this, news of the approval was widely shared.

The approval of GSKs Ojjaara (momelotinib) on Sept. 15 to treat patients with intermediate or high-risk myelofibrosis with anemia also drove a second spike in mentions. Ojjaara is a once-a-day, oral JAK1/JAK2 and activin A receptor type 1 inhibitor. HCPs were enthusiastic about the approval. Many cited the drugs potential to change clinical practice and expressed their eagerness to see the drug approved in the United Kingdom and European Union.

The findings form part of a wider study by leading digital insights consultancy, Creation Healthcare, and are based on an analysis of 2,379 English-language posts on X, the platform formerly called Twitter, by 1,555 HCPs throughout September 2023 surrounding the approval and launch of new products.

The analysts found that fewer HCPs discussed treatment approvals compared with the previous month, with 14% fewer product launch mentions compared with those in August.

Over the period, the three most shared stories from HCPs discussing product launches included an FDA press release on the updated mRNA COVID-19 vaccine booster approval, a New England Journal of Medicine article on The Accelerated Approval Program for Cancer Drugs Finding the Right Balance, and a GSK press release on the approval of Ojjaara for patients with myelofibrosis and anemia.

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Updated COVID-19 vaccines receive mixed support among health care professionals online - Healio

New study confirms safety and benefits of maternal COVID-19 vaccination for newborns – EurekAlert

October 25, 2023

Toronto, ON, October 23, 2023 Infants of pregnant women who received an mRNA COVID-19 vaccine during pregnancy had lower risks of severe health outcomes, neonatal death, and neonatal intensive care unit (NICU) admission, according to a new study from researchers at ICES and the University of Toronto.

Published in JAMA Pediatrics, the study included more than 140,000 infants in Ontario, and also showed that newborn and six-month readmissions to the NICU did not increase in infants of mothers vaccinated during pregnancy.

"Our results were consistent across the number of doses someone received during pregnancy, the trimester in which they were vaccinated, and the vaccine product they received, which gives us more confidence that there is no increase in the adverse newborn and infant outcomes we assessed," says lead author Sarah Jorgensen, a pharmacist, ICES post-doctoral trainee, and PhD candidate at the University of Toronto.

The researchers analyzed linked health records from ICES, and included 142,006 live births in Ontario, Canada, where the mother had received an mRNA vaccination during pregnancy. Expected deliveries between May 1, 2021 and September 2, 2022 were included. In total, 85,670 (60%) of infants were exposed to one or more COVID-19 vaccine doses in utero.

Study findings showed that:

One limitation of the study is that the analyses were restricted to live births, which could mean that the effects of vaccination on miscarriage and stillbirths were not observed. However, studies that have analyzed data from Ontario have not reported an increased risk of miscarriage or stillbirth in women who received COVID-19 vaccines during pregnancy. In fact, some studies found a lowered risk of stillbirth.

"Many women feel nervous about receiving vaccines during pregnancy, but our study will hopefully provide some reassurance on the safety of COVID-19 vaccine during pregnancy for newborns and young infants," says Jorgensen.

The study, Newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy: a population-based retrospective cohort study was published in JAMA Pediatrics.

Authors: Jorgensen S, Drover S, Fell D, Austin P, D'Souza R, Guttmann A, Buchan S, Wilson S, Nasreen S, Schwartz K, Tadrous M, Wilson K, Kwong J.

ICES is an independent, non-profit research institute that uses population-based health information to produce knowledge on a broad range of healthcare issues. Our unbiased evidence provides measures of health system performance, a clearer understanding of the shifting healthcare needs of Ontarians, and a stimulus for discussion of practical solutions to optimize scarce resources. ICES knowledge is highly regarded in Canada and abroad and is widely used by government, hospitals, planners, and practitioners to make decisions about care delivery and to develop policy. For the latest ICES news, follow us on X, formerly Twitter: @ICESOntario

FOR FURTHER INFORMATION PLEASE CONTACT:

Misty Pratt Senior Communications Officer, ICES Misty.Pratt@ices.on.ca 613-882-7065

Observational study

People

Newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy

23-Oct-2023

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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New study confirms safety and benefits of maternal COVID-19 vaccination for newborns - EurekAlert

Flu vaccine available to children from today | NorthernSound – Northern Sound

October 25, 2023

Children are eligible for free nasal flu vaccines from today.Last year, 1,274 children were hospitalised with flu and the Flunited campaign hopes to highlight this to parents at their launch today. "The vaccine is available free for two to 12-year-olds as a nasal vaccination, DCU Professor of Immunology Christine Loscher said.

"Its also available for 12 to 17-year-olds for free who have underlying conditions, the vaccine is also available to other children up to the age of 17. And of course, we also have the vaccine available to adults, which is in its normal format."

The vaccine can be obtained from GP clinics and pharmacies. "Its a nasal vaccination, so it is literally a quick sniff for a child, so very straightforward," Professor Loscher said.

"And we are really asking people to consider having their child vaccinated because it lessens the infection rate that we have in the country and therefore it will lessen the infections for all of the other age groups."

The Flunited campaign will be formally launched by GAA Mayo star Aidan OShea in Dublin this morning.

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Flu vaccine available to children from today | NorthernSound - Northern Sound

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