Category: Covid-19

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NIH to invest $29 million to address COVID-19 disparities | National Institutes of Health – National Institutes of Health

April 30, 2021

News Release

Thursday, April 29, 2021

To bolster research to help communities disproportionately affected by COVID-19, the National Institutes of Health is funding $29 million in additional grants for the NIH Community Engagement Alliance (CEAL) Against COVID-19 Disparities. This funding was supported by the American Rescue Plan. The awards will provide $15 million to 11 teams already conducting research and outreach to help strengthen COVID-19 vaccine confidence and access, as well as testing and treatment, in communities of color. An additional $14 million will fund 10 new research teams to extend the reach of COVID-19 community-engaged research and outreach.

The goal of this effort is to foster community-engagement research in communities which have been hit hardest by the pandemic, said Gary H. Gibbons, M.D., director, National Heart, Lung, and Blood Institute (NHLBI). The alliance is designed to meet people where they are with the help of trusted messengers, including family doctors, pastors, and community health workers, and to forge lasting partnerships to address health disparities.

Eleven research teams received $17 million in grants in 2020 to reach residents at risk of severe COVID-19 outcomes. Spread throughout the country, CEAL research groups have used different strategies to coordinate educational outreach, raise awareness about the importance of inclusive participation in COVID-19 testing, vaccine uptake, and clinical trials, and conduct research to understand barriers surrounding prevention and treatment. CEAL researchers also study the best ways to address these challenges and establish trust in the scientific process, while equitably distributing COVID-19 resources tailored to each community.

Its one thing to have strong national messages about the science behind vaccines, said Eliseo J. Prez-Stable, M.D., director, National Institute on Minority Health and Health Disparities (NIMHD). Its another to have those messages delivered by local, trusted sources, who can ensure questions from their communities are honestly and clearly addressed.

For example, mobile units in the Mississippi Delta helped rural residents access COVID-19 vaccines, while pop-up vaccine clinics played similar roles in California, Michigan, and other states. Focus groups in multiple CEAL regions identified information-based needs and perceptions about vaccines and treatment, including concerns about medical mistrust, which guided future outreach.

The most promising scientific discoveries benefit all populations and the way we ensure that is through inclusive research participation and community engagement, Prez-Stable added. CEAL researchers are creating the community-engaged model to transform research practice.

Throughout 2021, CEAL researchers will tap community leaders, trusted organizations, and experts familiar to their communities, including NIH Rapid Acceleration of Diagnostics (RADx) testing centers, state health departments, and certified diabetes educators, and community health workers. These community assets will partner with each other to strengthen a national response to COVID-19 by focusing on local outreach. As teams within the CEAL Alliance personalize these outreach strategies, they will also share their findings with each other and the broader community of those working to move the country past the pandemic.

The power of community-engaged partnerships extends beyond state borders, said Catherine Stoney, Ph.D., the CEAL Alliance scientific program lead and deputy director of the Center for Translation Research and Implementation Science at NHLBI. The CEAL Alliance provides a central research hub where findings from one region may inform or guide best practices in another.

CEAL, guided by community-engaged researchers and supported by trusted community organizations and messengers, is an NIH-wide effort co-led by NHLBI and NIMHD.

The 10 new research teams joining the CEAL Alliance include:

Jose Arturo Bauermeister, Ph.D., M.P.H.University of Pennsylvania, Philadelphia

Cheryl Himmelfarb, Ph.D., R.N.Johns Hopkins University, Baltimore

Matthew Kreuter, Ph.D., M.P.H.Washington University in St. Louis

Benjamin Linas, M.D.Boston Medical Center

Vivian Coln-Lpez, Ph.D., M.P.H.University of Puerto Rico Medical Sciences, San Juan

Molly Martin, M.D.University of Illinois at Chicago

Pearl McElfish, Ph.D.University of Arkansas for Medical Sciences, Little Rock

Donald Nease, M.D.University of Colorado Denver

Chau Trinh-Shevrin, DrPHNew York University School of Medicine, New York City

Lisa Cacari Stone, Ph.D.University of New Mexico, Albuquerque

For more information about the CEAL Alliance, visit theNIH COVID-19 communitiespage.

About the National Heart, Lung, and Blood Institute (NHLBI):NHLBI is the global leader in conducting and supporting research in heart, lung, and blood diseases and sleep disorders that advances scientific knowledge, improves public health, and saves lives. For more information, visitwww.nhlbi.nih.gov.

About the National Instituteon Minority Health and Health Disparities (NIMHD):NIMHD leads scientific research to improve minority health and eliminate health disparities by conducting and supporting research; planning, reviewing, coordinating, and evaluating all minority health and health disparities research at NIH; promoting and supporting the training of a diverse research workforce; translating and disseminating research information; and fostering collaborations and partnerships. For more information about NIMHD, visithttps://www.nimhd.nih.gov.

About the National Institutes of Health (NIH):NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

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NIH to invest $29 million to address COVID-19 disparities | National Institutes of Health - National Institutes of Health

Covid-19 vaccine myths: These reasons for not getting a shot don’t hold up. In fact, they’ll set the United States back – WLS-TV

April 30, 2021

Americans have an easy way to crush Covid-19 -- one that would let businesses fully reopen safely, ditch the need for social distancing and restore a mask-free return to normalcy.

But many Americans don't want to get vaccinated as myths and misunderstandings spread.

"We were at 75% of adults saying they wanted the vaccine. Now we're down to, in those surveys, about 67%."

Vaccine hesitancy is a big problem for several reasons:

-- Health experts say we need at least 70-85% of the US population immunized to reach herd immunity.

-- The longer people stay unvaccinated, the more chances a virus has to mutate. And if the mutations are significant, they could lead to more troubling strains that might evade vaccines.

-- 'Long Covid' is real. Even young athletes have suffered brain fog, chest pains and shortness of breath months after infection.

"Even for young people who consider their risk of severe Covid to be low, the long-term consequences can be quite serious," said Dr. Francis Collins, director of the National Institutes of Health.

"So long Covid represents one more reason to encourage everyone age 16 and over to get vaccinated as quickly as possible."

But rampant myths and unnecessary concerns stand in the way. Here are some of the most popular arguments for not getting vaccinated and why doctors want to set the record straight:

'We don't know what the long-term side effects are'

Any adverse side effects from vaccines almost always "show up within the first two weeks, and certainly by the first two months," said Dr. Ashish Jha, dean of the Brown University School of Public Health.

That's why he and many other health experts asked the US Food and Drug Administration to wait at least two months after trial participants had been inoculated before considering whether to give emergency authorization to Covid-19 vaccines.

"If there were going to (be) problems ... they would become apparent within two months of people getting vaccinated," he said. "That's what the FDA waited for."

The most serious vaccine side effects in history have all been caught within six weeks, said Dr. Paul Offit, director of the Vaccine Education Center at the Children's Hospital in Philadelphia and a member of the FDA's Vaccines and Related Biological Products Advisory Committee.

"I would say, please tell me what vaccine has ever been shown to cause a long-term side effect that was not picked up in the first two months," said Offit, a co-creator of the rotavirus vaccine who has studied vaccinology for more than four decades.

"The smallpox vaccine could cause inflammation of the heart muscle. The oral polio vaccine was a rare cause of polio -- it occurred in roughly 1 in 2.4 million doses. ... The yellow fever vaccine is a rare cause of ... yellow fever. All those occurred within six weeks of getting a dose," he said.

There may be very rare side effects that aren't immediately found in clinical trials. But that's due to the extreme rarity of those side effects -- "not because it's a long-term problem," Offit said.

"Sometimes you're not going to pick it up initially because it's extremely rare, so you aren't going to pick up a one-in-a-million risk in a trial of 44,000 people," he said.

Pfizer/BioNTech and Johnson & Johnson had about 44,000 participants in each of their trials. Half the volunteers got vaccinated, and the other half got placebos.

The Moderna trial had about 30,000 participants, with half receiving vaccines and half receiving placebos.

And because coronavirus is highly contagious -- killing more than half a million Americans and leaving many survivors with long-term complications -- you're much better off getting the vaccine.

'The vaccine might hurt my fertility'

This is pure nonsense, Offit said.

There's no evidence that people have lost any fertility because of the Covid-19 vaccines.

The rumor apparently started with the myth that the coronavirus spike protein, which is mimicked when you get a vaccine, also mimics the protein on the surface of placental cells, Offit said.

"So the false notion was that when you're making an immune response to the SARS-CoV-2 spike protein, you also were inadvertently making a response to a placental protein -- which would then make you less likely to be fertile," Offit said.

"So it's all nonsense. It's not true."

The US Centers for Disease Control and Prevention also said there's no link between any vaccines and fertility.

"If you are trying to become pregnant now or want to get pregnant in the future, you may receive a COVID-19 vaccine when one is available to you," the CDC says.

"There is currently no evidence that any vaccines, including COVID-19 vaccines, cause fertility problems."

The benefits of getting vaccinated if you're pregnant or trying to become pregnant far outweigh the risks, because pregnancy puts a person at higher risk for severe Covid-19 illness.

And some research suggests Covid-19 vaccines provide some level of protection to newborns.

Refusing the Covid-19 vaccine actually impacts a lot of people -- yourself, your loved ones, even the country as a whole.

"When people say, 'What do you care? You're vaccinated. I'm going to choose not to be vaccinated. You're vaccinated, so you're good'" -- that makes three false assumptions, Offit said.

"First of all, the vaccines aren't 100% effective." So even if your friends and family are vaccinated, but you're not vaccinated, you can still carry and spread the virus to your loved ones.

And as Americans go back to crowded bars, concerts, sporting events and movie theaters, the need for mass vaccination becomes even more important.

Second, it's a mistake to think everyone who wants a vaccine can just get one. "Some people are on cancer chemotherapy. They can't be vaccinated -- they depend on the herd to protect them," Offit said.

So many of the most vulnerable Americans are counting on fellow Americans to get vaccinated.

"And third, by not being vaccinated, or being part of a reasonably sized group of people who are choosing not to get the vaccine, you're allowing the virus to continue to replicate. When it's allowed to continue to replicate, it will create mutations, which could then cause variants that are completely resistant to the immunity induced by natural infection or immunization."

In other words: Failing to get a vaccine could make the vaccines less effective. And that could ruin everyone's vaccinations -- throwing the country backward in this pandemic.

'I'm young and healthy, so I don't need to get vaccinated'

It's critical for young, healthy adults to get vaccinated. Many of those who refused have already paid a price.

A highly contagious strain is hitting young adults hard. The B.1.1.7 variant is now the most dominant strain of coronavirus spreading in the United States. And unlike the original strain, this one is heavily impacting young people.

"In the Upper Midwest, we're starting to see lots of younger adults getting sick and going to the hospital from Covid because of the B.1.1.7 variant," said Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine.

"So remember that the B.1.1.7 variant is different from past types of Covid infections that we've seen -- more serious and possibly more severe disease among younger people."

Young adults can get long-term Covid-19 complications. Plenty of young, healthy people have turned into Covid-19 "long-haulers."

Many have suffered chronic fatigue, chest pain, shortness of breath and brain fog months after their infection.

And a recent study found that 30% of people who had Covid-19 still had symptoms up to nine months after infection.

"Covid-19 doesn't have to kill you to wreck your life," said Dr. Jonathan Reiner, professor of medicine and surgery at George Washington University.

Young adults can be easy transmitters of coronavirus. Several states recently reported spikes in young people with Covid-19. "A lot of the spread is happening among younger people," Jha said. "That's the group that is moving around, kind of relaxing, getting infected."

Young adults can be victims of their strong immune systems. Doctors have noticed some young, previously healthy patients suffer from Covid-19 cytokine storms. That's basically when someone's immune system overreacts -- potentially causing severe inflammation or other serious symptoms.

"We've certainly seen people come into our hospital, very young people (in their early 20s) ... need to be put on ECMO, which is basically a heart-lung machine, for days or even weeks because they come in with cardiomyopathy, which is a response to a cytokine storm," Reiner said.

If too few people get vaccinated, we'll never reach herd immunity. "It's important to vaccinate as many adults as possible as soon as possible," internal medicine specialist Dr. Jorge Rodriguez said.

"If you want to open up America, get vaccinated."

'These vaccines only have emergency use authorization, not full FDA approval'

It's true that the Pfizer/BioNTech, Moderna and Johnson & Johnson vaccines have emergency use authorization from the FDA and not full approval yet.

But that's only because not enough time has passed to show how long the vaccines stay effective, Offit said.

"Frankly, the only real difference was in length of follow-up," he said. "Typically, you like to see efficacy for a year or two years."

But with Covid-19 vaccines, "you couldn't do that. You couldn't do a one- or two- or three-year study ... because the virus was killing hundreds of thousands of people. So we wanted to get it out there."

He stressed that the vaccines' EUA status doesn't mean they're less safe. As a member of the FDA vaccine advisory committee, Offit said the vaccines are reviewed with the same level of scrutiny as they would to get full approval.

Offit said he's confident the vaccines will get full FDA approval.

"The effectiveness and efficacy data in the Phase 3 trials and now in the real world ... is excellent," he said.

'I've already had Covid-19, so I don't need to be vaccinated'

Even if you've had coronavirus, you should still get vaccinated because the immunity you get from vaccination will likely be longer or stronger than the immunity you got after getting infected, health experts say.

"That's true for a number of vaccines -- the human papillomavirus (HPV) vaccine induces immunity better than natural infection. The tetanus vaccine does," he said.

When it comes to the two-dose vaccines -- those from Pfizer/BioNTech and Moderna -- people who've already had coronavirus should still get both doses, emergency medicine physician Dr. Leana Wen said.

Those vaccines were studied in people taking both doses, and that's what experts know to be effective. It's not clear how long protection after just one dose might last.

"We also don't know how long protection will last after having coronavirus, so you should still be (fully) vaccinated," Wen said.

'I don't want to get Covid-19 from the vaccine'

It's literally impossible to get Covid-19 from any of the vaccines used in the US because none of them contains even a piece of real coronavirus.

Here's how each vaccine was made.

'My faith will protect me, so I don't need to get vaccinated'

Among religious groups in the US, "white evangelical Protestants stand out as the most likely to say they will refuse to get vaccinated (26%), with an additional 28% who are hesitant," according to a study by the Public Religion Research Institute and Interfaith Youth Core.

Some experts say anti-Covid-19 vaccine sentiment among evangelicals is fueled by a distrust in government, ignorance about how vaccines work and misinformation.

"If you believe that God created us in his image, including being able to think and reason, we've been able to think and reason a lot of these diseases away" thanks to vaccination, he said.

"We don't die from smallpox anymore. Children aren't permanently paralyzed by polio anymore in the United States. It's a good thing. That's because God gave us a brain to think and reason with. So use it."

'I might not be able to afford a vaccine'

"It's all free. The government is paying for this," Offit said.

This is one message public officials could do a better job explaining, he said.

"I never hear them described as free, I think because it's always assumed that people know they're free," Offit said.

But "maybe for all those commercials you see on TV ... they should make it clear you don't have to pay this."

For those who might lack internet access, Offit said it'd be a good idea for state or local health departments to send flyers in the mail explaining when and how people can get vaccinated -- and reminding them it's free.

The bottom line: Not getting vaccinated could set everyone back

If you want to protect yourself, your friends, your family and the economy, get vaccinated. Otherwise, you'll be part of the problem -- not the solution.

"This virus is continuing to mutate," Offit said. "The thing I'm most worried about is that this virus will mutate to the point that immunity induced by natural infection or vaccination doesn't work at all. That's the most important reason to vaccinate."

The longer a virus circulates among unvaccinated people, the more opportunities it has to mutate. And if the mutations are significant, they can lead to more problematic variants -- including some that could partially or fully escape vaccine protection.

"It's already starting to happen," Offit said, citing the B.1.351 and P.1 variants. While vaccines are still effective against those strains, "these variants have now started to escape from the immunity of natural infection or immunization. They don't completely escape, but they've started to escape."

So the key to ending this pandemic isn't just getting vaccinated. It's getting vaccinated as soon as possible, before the virus mutates into variants that we can't control with our current vaccines.

"The vaccine is the most important pathway to ending this pandemic. That means we've got to get everyone in our country vaccinated," US Surgeon General Dr. Vivek Murthy said.

"Now what we've got to do is, No. 1: Get the vaccine. No. 2: Turn around and look at our family and friends and ask if they're going to get vaccinated. If they need help, that's what we've got to do."

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Covid-19 vaccine myths: These reasons for not getting a shot don't hold up. In fact, they'll set the United States back - WLS-TV

Wolf Administration Highlights Impact of COVID-19 on Individuals with Substance Use Disorders and Collaborative Projects Through the Opioid Disaster…

April 30, 2021

Harrisburg, PA - Wolf Administration officials today outlined the impacts of COVID-19 on people living with substance use disorders (SUD) and highlighted projects and collaborations made possible through the opioid disaster declarations creation of the Opioid Command Center.

As we continue to evaluate 2020 overdose trends, we are seeing a significant uptick in fatal overdoses, Acting Secretary of Health Alison Beam said. We know that the COVID-19 pandemic exacerbated the challenges for people with the disease of addiction. Because of the disaster declaration in place, the entire Opioid Command Center, including the Prescription Drug Monitoring Program, is able to offer a variety of support to people in need.

While the 2020 counts are expected to increase further since finalized death records for overdose deaths are often delayed into the following year, there have been 4,880 drug overdose deaths reported thus far. This preliminary data, as of March 2021, indicates there were at least 422 more deaths in 2020 than in 2019. Since the overdose epidemic began, the most overdose deaths in Pennsylvania during a single year was 5,396 in 2017.

To understand potential reasons for the increase in overdose deaths and to identify opportunities to assist, the Opioid Command Center is holding meetings with counties, including Pike, Cambria, Allegheny, and Lebanon, that experienced the most significant increases in overdoses during 2020. Meeting topics include fatal overdoses, emergency department visits for overdose, and EMS naloxone administrations and strategies to reduce overdoses at a local level.

The state and local partnerships brought together by the command center have never been more important, said DDAP Secretary Jen Smith. As we navigate the coming months and impacts of COVID-19 on individuals with a substance use disorder and those in recovery, the Wolf Administration is committed to continuing the fight to ensure all Pennsylvanians have access to necessary, life-saving resources.

Through the collaborative effort of the command center, the Wolf Administration has been able to break down decade-long silos across agencies and work together to make a positive impact on Pennsylvanians struggling with the disease of addiction.

Prescription Drug Monitoring Program

Since the Prescription Drug Monitoring Program (PDMP) launched in 2016, there has been a 58 percent reduction in the number of individuals receiving a high dosage of opioid medication, a 54 percent reduction in the number of individuals receiving a dangerous drug combination of opioids and benzodiazepines, and a 38 percent reduction in opioid prescribing overall. In addition, there has been a 30 percent increase in the prescribing of buprenorphine, which is used to treat opioid use disorder as part of Medication-Assisted Treatment (MAT).

Naloxone for First Responders Program

Since the launch of the Naloxone for First Responders Program (NFRP) in November 2017, Centralized Coordinating Entities (CCEs) have distributed 92,980 kits (2 doses each) of Narcan to first responders across the commonwealth, including 29,578 kits distributed in 2020. These efforts have resulted in more than 17,970 overdose reversals reported to date by CCEs, including 5,282 reversals reported in 2020.

In March of 2021, the command center announced the availability of the Statewide Naloxone Allocation Request Portal which allows eligible organizations serving high-risk populations the ability to request additional naloxone nasal spray.

Police Diversion to Treatment

As of March 2021, the Police Diversion to Treatment project continues to support seven local Single County Authorities in expanding or creating collaboratives between law enforcement, treatment professionals, and recovery support providers to establish diversion programs aimed at offering treatment-based alternatives to arresting, booking, and incarceration for minor criminal offenses.

To date, 322 law enforcement officers have received training on a variety of topics related to police diversion, and 122 individuals were referred to and admitted into SUD treatment versus incarceration.

Medication-Assisted Treatment in State Corrections Facilities

In January 2018, after Governor Wolf signed the first Opioid Disaster Declaration, the Wolf Administration directed that MAT be provided within the Department of Corrections (DOC) prison system. During 2018, the Vivitrol program expanded to all 25 state prisons and in April 2019, the DOC began a pilot project program offering Sublocade injections at State Correctional Institution Muncy. In February 2020, the Wolf Administration announced more than $1.2 million in grants to nine county jails to support the county jail-based MAT program.

Supporting Pennsylvania Veterans

The Department of Military and Veteran Affairs (DMVA) continues to support a variety of existing and new programs tailored to the unique needs of veterans with opioid and stimulant use disorders. These programs provide a combination of evidence-based co-occurring treatment including treatment courts, recovery support, and robust case management services.

Since September 30, 2020, across 11 organizations, and despite barriers related to COVID-19, a total of 432 Veterans have been served, and 53 staff have received specialized training related to these projects. Of the over 400 Veterans served, 98 percent of participants report a reduction in substance use, and 88 percent report an overall improvement in quality of life.

Our collaboration with DDAP to provide grants to veteran advocates is making a huge difference by educating and helping veterans overcome their substance use disorder, said Brig. Gen. (ret.) Maureen Weigl, Department of Military and Veterans Affairs deputy adjutant general for Veterans Affairs. However, now is not the time to take our foot off the pedal. We need to continue working together with a focus on raising awareness and reducing the number of veterans and members of the general public with a substance use disorder to zero.

The Opioid Command Center, established in January 2018 when Gov. Wolf signed the first opioid disaster declaration, continues to meet weekly to discuss the opioid crisis and overdose deaths across the commonwealth. The command center is staffed by personnel from 17 state agencies and the Office of the Attorney General, spearheaded by the Department of Health (DOH) and Department of Drug and Alcohol Programs (DDAP).

Last year the Opioid Command Center released its strategic plan to address substance use from a comprehensive approach. Work to address the opioid crisis focuses on four areas: prevention, rescue, treatment, and recovery. Efforts over the past several years, working with state agencies, local, regional, and federal officials, have resulted in significant action to address the opioid crisis.

To learn more about those efforts, visit http://www.pa.gov/opioids.

MEDIA CONTACTS: Barry Ciccocioppo, Health, ra-dhpressoffice@pa.gov Ali Gantz, DDAP, ra-dapressoffice@pa.gov Joan Nissley, DMVA, jnissley@pa.gov

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Wolf Administration Highlights Impact of COVID-19 on Individuals with Substance Use Disorders and Collaborative Projects Through the Opioid Disaster...

Norway to speed up first COVID-19 jabs by delaying second dose – Reuters

April 30, 2021

Norway said on Friday it will extend the time between first and second doses of COVID-19 vaccines to 12 from six weeks for most adults under the age of 65 in order to reach its first vaccination target sooner than planned.

The decision could allow all adults in Norway to receive a first jab by July 25 the Institute of Public Health (FHI) and health ministry said in a statement.

The extension relates to both the Pfizer-BioNTech (PFE.N), (22UAy.DE) and Moderna (MRNA.O) vaccines, which are the only ones currently used in Norway.

Norway's FHI had previously estimated that all adults would be offered their first dose by Aug 29.

"Increasing the interval will allow many more to be vaccinated earlier. This will prevent serious illness and death, and reduce the overall level of infection in society," Health Minister Bent Hoeie said.

Studies have shown that the difference in effect from extending the interval at which the two doses are given is minimal, the ministry added.

If Norway decides to also use COVID-19 vaccines made by AstraZeneca (AZN.L) and Johnson & Johnson (JNJ.N), this could speed up the process further.

Norwegian authorities last month suspended the rollout of the AstraZeneca vaccine after a small number of younger, inoculated people were hospitalised for a combination of blood clots, bleeding and a low count of platelets.

Some later died. read more

A decision on whether to use Johnson & Johnson's vaccine is on hold over similar concerns and a government-appointed commission is due to advise on the potential use of both vaccines by May 10.

Our Standards: The Thomson Reuters Trust Principles.

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Norway to speed up first COVID-19 jabs by delaying second dose - Reuters

Conn. Has Lowest Increase in COVID-19 Cases in 6 Months: Governor – NBC Connecticut

April 30, 2021

The governor said Connecticut has the lowest increase in COVID-19 cases that's been seen in six months. He said this may be a result of more residents getting vaccinated against the virus.

The state's positivity rate is at 1.34% and 486 people tested positive out of 36,200 tests performed since Wednesday.

Daily coronavirus cases have seen a decrease of approximately 50% over the past couple of weeks, according to Chief Operating Officer Josh Geballe.

Full coverage of the COVID-19 outbreak and how it impacts you

Net hospitalizations are down by four at 403. That's the lowest number seen in more than a month.

Four more virus-related deaths have been reported. The death toll is now at 8,084, state officials said.

The state's positivity rate was 2.29% on Wednesday.

Starting Saturday, some COVID-19 restrictions across Connecticut will be lifted. This includes moving the business curfew back to 12 a.m. and lifting outdoor restrictions. There will be no table size limit and alcohol without food will be allowed.

The CDC doesn't want you going out with friends right after full vaccination, but is encouraging waiting two weeks for coronavirus antibodies to kick in. NBC News Medical Correspondent Dr. John Torres weighs in on those guidelines and also discusses the COVID-19 crisis in India, where hundreds of thousands of cases are being reported each day, and oxygen and ventilators are in high demand.

Governor Ned Lamont said all colleges in the state have completed first dose clinics.

There are over 100 vaccination clinics offering walk-up appointments. For a list of these clinics, click here.

Nearly 1.9 million first doses of the COVID-19 vaccine have been administered across the state. A total of 1.32 million people are fully vaccinated, according to state officials.

The Johnson & Johnson vaccine is once again being administered at clinics across Connecticut. Approximately 5,000 doses have been given out since the pause was lifted last week.

Large event and large employer vaccine clinics are available, according to the governor.

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Conn. Has Lowest Increase in COVID-19 Cases in 6 Months: Governor - NBC Connecticut

Tracking COVID-19 in Alaska: 161 cases and no deaths reported Thursday – Anchorage Daily News

April 30, 2021

We're making this important information available without a subscription as a public service. But we depend on reader support to do this work. Please consider supporting independent journalism in Alaska, at just $1.99 for the first month of your subscription.

A slight increase in the daily case rate since March has somewhat plateaued. However, most regions in the state are still in the highest alert category based on their current per capita rate of infection, and health officials continue to encourage Alaskans to wear face coverings in public, avoid large gatherings, wash their hands frequently and get vaccinated against COVID-19 to prevent further spread.

By Thursday, there were 54 people with confirmed or suspected cases of COVID-19 in hospitals throughout the state, far below a peak in late 2020 but slightly up compared to recent days.

By Thursday, 308,040 people about half of all Alaskans eligible for a shot had received at least their first dose. At least 261,074 people about 44% of Alaskans 16 and older were considered fully vaccinated, according to the states vaccine monitoring dashboard.

Alaska in January led the country in per capita vaccinations, but has now fallen to 22nd place among all 50 states and Washington, D.C., according to data from the U.S. Centers for Disease Control and Prevention.

You can visit covidvax.alaska.gov or call 907-646-3322 to sign up for a vaccine appointment; new appointments are added regularly. The phone line is staffed 9 a.m. to 6:30 p.m. on weekdays and 9 a.m. to 4:30 p.m. on weekends.

Of the 158 cases reported among Alaska residents on Thursday, there were 49 in Anchorage plus six in Eagle River; 34 in Fairbanks; 20 in Wasilla; 16 in North Pole; nine in Palmer; four in Soldotna; two in Kodiak; two in Ketchikan; one in Kenai; one in Seward; one in Sterling; one in Delta Junction; one in Houston; one in Utqiagvik; one in Juneau; one in Unalaska; and one in Chevak.

Among communities smaller than 1,000 people that arent named to protect residents privacy, there were two in the Fairbanks North Star Borough; one in the Prince of Wales and Hyder Census Area; one in the Aleutians East Borough; one in the Bethel Census Area; and two in the Kusilvak Census Area.

There were also three new cases among nonresidents: one in Wasilla, one in Juneau and one in an unidentified region of the state.

While people might get tested more than once, each case reported by the state health department represents only one person.

The states data doesnt specify whether people testing positive for COVID-19 have symptoms. More than half of the nations infections are transmitted from asymptomatic people, according to CDC estimates.

Of all the tests conducted over the past week, 2.8% came back positive.

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Tracking COVID-19 in Alaska: 161 cases and no deaths reported Thursday - Anchorage Daily News

Amish In Ohio Aren’t Getting Vaccinated Despite High COVID Infections, Deaths : Shots – Health News – NPR

April 30, 2021

Holmes County, Ohio, General Health District staff members (from left) Michael Derr, Jennifer Talkington and Abbie Benton prepare materials for a COVID-19 vaccine clinic this month inside St. Peter's Catholic Church in Millersburg. Anna Huntsman/WCPN hide caption

Holmes County, Ohio, General Health District staff members (from left) Michael Derr, Jennifer Talkington and Abbie Benton prepare materials for a COVID-19 vaccine clinic this month inside St. Peter's Catholic Church in Millersburg.

The Amish communities of northeast Ohio engage in textbook communal living. Families eat, work and go to church together, and through the pandemic, mask-wearing and social distancing have been spotty. As a result, these communities have experienced some of the state's highest rates of infection and deaths.

Nevertheless, health officials are struggling to get residents vaccinated. Holmes County, where half of the population is Amish, has the lowest vaccination rate in Ohio, with just 10% of its roughly 44,000 residents fully vaccinated.

Less than 1% of Amish have received any doses of vaccine, according to Michael Derr, the county's health commissioner.

In an effort to increase that number, health officials are holding vaccination clinics in rural areas. They've also reached out to bishops and community leaders to spread the word about the safety of the vaccines. Still, few Amish residents are showing up to the health department's clinics.

Marcus Yoder, who lives in Holmes County, was born Amish and is now Mennonite and still has close ties to the Amish community. He says the few Amish who are getting vaccinated are doing so privately through doctors' offices and small rural clinics and they are keeping it to themselves.

"There were Amish people getting the vaccination the same day I was ... and we all kind of looked at each other and smiled underneath our masks and assumed that we wouldn't say that we saw them," Yoder says.

He says many Amish don't want to get vaccinated because they already had COVID-19 and believe the area has reached herd immunity.

Another main driving force is "the misinformation about COVID itself that it's not more serious than the flu," says Yoder, who runs a history center about the Amish and Mennonite. "They're saying, 'Well, it didn't affect me that much. Look at all these old people who survived.' "

A man zips by on a walking and biking trail in Holmes County, home to one of the largest settlements of Amish in the United States. Anna Huntsman/WCPN hide caption

A man zips by on a walking and biking trail in Holmes County, home to one of the largest settlements of Amish in the United States.

Some Amish residents are skeptical of the safety and effectiveness of the vaccines, and anti-vaccination conspiracy theories also spread throughout the community. There is also a lack of awareness about the more contagious variants spreading across the country, Yoder says.

"I think we're going to see some more cases in our community, unfortunately, because of this," he says. "There simply is a lot of COVID news fatigue. They simply do not want to hear about it, and that's really unfortunate."

While some sort of herd immunity could explain why Holmes currently has a low incidence of new cases, Derr at the health department is concerned that those who previously had the virus may not be protected.

"As a region, we definitely surged over the winter, and we know that that happened about 90 days ago," Derr says. "We're primed and ready for another surge because we're not vaccinating enough."

Health officials in Indiana and Pennsylvania which, combined with Ohio account for the largest Amish communities also are ramping up outreach in heavily Amish areas. Local health departments in Pennsylvania's Lancaster County, home to the largest Amish population in the country, are connecting with Amish bishops to try to spread the word about the vaccines.

The widespread reluctance to get vaccinated in Amish communities is not surprising to West Virginia University sociologist Rachel Stein, who studies Amish populations across the country.

"We as non-Amish are more on board with preventative medicine," Stein says. "They certainly don't have that mindset that we need to do things to stop this from happening."

Instead, she says there's an acceptance that people will get sick and get better or not. While childhood vaccinations have increased in Ohio's Amish communities in recent years, adults are still more hesitant, she adds.

"There's oftentimes frequent breakouts of whooping cough in a settlement, and it's just like ... 'This is happening now. We're in whooping cough season, and so it's time to deal with this sort of thing,' " she says.

In 2014, a measles outbreak spread rapidly through Ohio's largely unvaccinated Amish communities. Even after this experience, many Amish residents still choose not to vaccinate their children against other diseases.

The low vaccination interest in Holmes County tracks national trends showing residents of rural areas are less likely to consider getting vaccinated.

A recent poll from the Kaiser Family Foundation found 3 in 10 rural residents will "definitely not" get the COVID-19 vaccine unless it is mandated.

Yoder says he thinks the best path forward is to encourage Amish residents who were vaccinated to talk openly about their positive experience getting the shots.

"I think that hammering people for not doing it will not get us anywhere," Yoder says. "Some of the local business leaders have done very, very well at saying, 'Look, let's get the vaccination so we don't have to wear masks in the future, so we don't have to worry about social distancing as much in the future.' And they've used that tact and that has been a healthy way to approach it."

Derr, the Holmes County health commissioner, is trying to get business owners who employ Amish workers to encourage their staff to get the shot. Officials hope eventually to hold vaccine clinics at these businesses and take the shots to them, but not every business owner is on board with that yet, he says.

"People are going to listen to their friends and their family, people who they interact with more, and it's going to be that telephone effect," Derr says. "The more and more people we tell about it and the better experiences they have, word will get around."

Derr expects more Amish will get vaccinated in the fall after the shots have been around for some time but worries the community could see a spike in cases long before then.

This story comes from NPR's partnership with Cleveland's ideastream and Kaiser Health News.

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Amish In Ohio Aren't Getting Vaccinated Despite High COVID Infections, Deaths : Shots - Health News - NPR

U.S. Pledges Medical Aid To India, Where COVID-19 Is Overwhelming Hospitals – NPR

April 26, 2021

The body of a person who died of COVID-19 being laid for cremation on Sunday in Noida, India. Sunil Ghosh/Hindustan Times via Getty Images hide caption

The body of a person who died of COVID-19 being laid for cremation on Sunday in Noida, India.

The United States will make more medical aid available to India in an effort to fight an alarming spike in COVID-19 cases. The pledge came during a phone call between White House national security adviser Jake Sullivan and Indian national security adviser Ajit Doval on Sunday, as India has become the epicenter of the global coronavirus pandemic and the country's health system is collapsing.

"Just as India sent assistance to the United States as our hospitals were strained early in the pandemic, the United States is determined to help India in its time of need," National Security Council Spokesperson Emily Horne said in a statement, which went on to say that the U.S. will allow for the export of certain raw material urgently needed for vaccine production, as well as sending test kits, ventilators and personal protective equipment, among other aid.

The U.S. had previously banned the export of raw vaccine materials, stating an obligation to take care of Americans first.

India reported nearly 350,000 new cases on Sunday, more than any country on any day since the pandemic began, the fourth day in a row the country has broken that grim world record. Many worry case numbers are woefully undercounted since test kits are hard to come by, and hospitals are completely overrun.

The sudden spike has caught the country completely off guard. In late January and early February of this year, cases were at record lows, and the Indian government declared an endgame to the pandemic. Restrictions were relaxed, travel resumed and gatherings came back.

Now cases and deaths have skyrocketed. Crematoriums are running day and night, unable to keep up with the bodies. There are desperate pleas for oxygen, hospital beds and medicine.

Oxygen is by far the biggest need in the country right now. Hospitals are trying to ration oxygen for the patients who are able to secure a hospital bed, which is difficult in itself. Hundreds, possibly thousands, die each day with doctors unable to help.

One longtime journalist who couldn't get treatment live-tweeted his declining oxygen levels until he died.

"I have never felt so desperate or helpless," Dr. Trupti Gilada said in a Facebook video she recorded of herself, weeping as she huddled in her car outside the Mumbai hospital where she works. "We are seeing young people. We have a 35-year-old who's on a ventilator. Please pray for our patients."

Sunday's pledge also said that the United States was urgently "pursuing options to provide oxygen generation," and would be deploying a team of public health advisers from the Centers for Disease Control and Prevention and the U.S. Agency for International Development to work with health officials in India and at the U.S. Embassy.

Lauren Frayer contributed reporting from Mumbai.

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U.S. Pledges Medical Aid To India, Where COVID-19 Is Overwhelming Hospitals - NPR

Fighting misinformation in the time of COVID-19, one click at a time – World – ReliefWeb

April 26, 2021

The United Kingdom and WHO collaborate to manage the infodemic

Acting on the wrong information can kill. In the first 3 months of 2020, nearly 6 000 people around the globe were hospitalized because of coronavirus misinformation, recent research suggests. During this period, researchers say at least 800 people may have died due to misinformation related to COVID-19*.

At its extreme, death can be the tragic outcome of what the World Health Organization has termed the infodemic, an overabundance of information --- some accurate, some not --- that spreads alongside a disease outbreak. False information runs the gamut, from discrediting the threat of COVID-19 to conspiracy theories that vaccines could alter human DNA.

Though they aren't new, in our digital age infodemics spread like wildfire. They create a breeding ground for uncertainty. Uncertainty in turn fuels skepticism and distrust, which is the perfect environment for fear, anxiety, finger-pointing, stigma, violent aggression and dismissal of proven public health measures --- which can lead to loss of life.

To try to control the COVID-19 infodemic, WHO has teamed up with the United Kingdom Government to create and distribute content to combat the spread of misinformation through a series of communication campaigns. This was one of several initiatives to combat misinformation taken by WHO on its own and with partners since the start of the COVID-19 outbreak.

Stop the Spread

'Stop the Spread' rolled out on BBC World television, website and apps during May and June 2020. It aimed to raise the public's awareness of the volume of misinformation around COVID-19 and encourage people to double check information, therefore limiting the damage and spread of false information.

'Reporting Misinformation', launched in August, galvanized people to not only verify information but showed them how to report misinformation to various social media platforms.

Alex Aiken, Executive Director of UK Government Communications, said,"The UK and the World Health Organization have a long history of collaboration. As the pandemic hit globally and the world sought collective action on the additional threat from the infodemic, our partnership was made even stronger."

"We are incredibly proud of the joint communications work we have done to strengthen global health security and vaccine confidence. The issue of infodemics is of enormous importance and the UK will be leading a global response under our G7 Presidency this year," he added.

The Reporting Misinformation campaign reached millions of people globally and social media messages were shared in 5 international languages including English, French, Spanish, Arabic and Russian. At its launch it became the second most viewed COVID-19 related page on the WHO website.

In the early days of the pandemic, much of the misinformation focused on whether COVID-19 was in fact a serious disease, whether people could protect themselves with public health measures like mask-wearing, as well as erroneous treatments and cures.

Misinformation matters

A year into the pandemic, vaccines are being rolled out, and information about them --- some reliable and some not --- is everywhere.

"Public trust in science and evidence is essential for overcoming COVID-19," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. "Therefore, finding solutions to the infodemic is as vital for saving lives from COVID-19 as public health measures, like mask-wearing and hand hygiene, to equitable access to vaccines, treatments and diagnostics."

Low rates of vaccine acceptance are a concern across the globe. Data released in January 2021 by the Johns Hopkins Centre for Communication Programs** suggest that across 23 countries, only 63 percent of respondents will accept a vaccine.

That is well below the 75 percent minimum estimate recommended by public health experts for a population to reach "herd immunity" --- the point where enough of the community has been vaccinated against COVID-19 to make further spread unlikely.

The data suggest that while there is a large segment of the population anxious to be vaccinated right away and a much smaller group adamantly opposed to getting a shot, there is a larger middle portion who are undecided and can be motivated to get the vaccine.

To boost their motivation, other UK Government-WHO collaborative campaigns have included an array of social media infographics and messages across platforms to explain the safety of COVID-19 vaccines.

The assets share positive messages which respond to unfounded concerns about the speed at which vaccines have been developed by explaining this is in part due to the unprecedented levels of scientific collaboration, funding and worldwide volunteers combined with capacity to ensure vaccine safety. Once vaccines are authorized through the regulatory process, including the assessment of safety and efficacy from phase III clinical trials, WHO's Strategic Advisory Group of Experts on Immunization (SAGE) will issue vaccine-specific policy recommendations.

Spotting fake news via Go Viral!

In addition to powerful social media messages, an innovative online game called Go Viral! was created, based on previous research which has shown just one play can reduce perceived reliability of fake news by an average of 21%.

The game was developed as a partnership between Cambridge University and the UK Cabinet Office.

Exposing the most pervasive infodemic tactics, players discover how real news gets discredited by exploiting fake doctors and remedies, and how false rumours such as the notorious 5G conspiracy get shared and promoted. Players are provided with a shareable score and connected to WHO's COVID-19 'mythbusters'.

The collaboration aims to get more translations of the game online with English, German and French versions already out.

Although the infodemic cannot be stopped, it can be managed through campaigns and collaborations like these. By showing people how to recognize and report misinformation and improve their media literacy, we can turn the tide on the infodemic tsunami and save lives.

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Fighting misinformation in the time of COVID-19, one click at a time - World - ReliefWeb

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