Category: Covid-19

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ACCEL Lite: Cardiovascular Drug Interactions with Paxlovid …

July 10, 2023

Millions of people are being prescribed Paxlovid for COVID-19 treatment; many of them are on cardiovascular medications. Paxlovid can have potentially harmful interactions with commonly prescribed cardiovascular medications and hence it is crucial to be aware of them and build a strategy to avoid them while providing effective treatment for COVID-19.

In this interview, Sarju Ganatra MD, FACC, and Joseph E. Marine MD, MBA, FACC, discuss Cardiovascular Drug Interactions with Nirmatrelvir/Ritonavir in Patients with COVID-19.

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Clinical Topics: COVID-19 Hub, Acute Coronary Syndromes, Anticoagulation Management, Prevention

Keywords: ACCELLite, Ritonavir, COVID-19, Drug Interactions, Cardiovascular Agents

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ACCEL Lite: Cardiovascular Drug Interactions with Paxlovid ...

China says 239 people died from COVID-19 in June in a significant …

July 10, 2023

BEIJING (AP) China reported Thursday that 239 people died from COVID-19 in June in a significant uptick months after it lifted most containment measures.

The Chinese Center for Disease Control and Prevention had reported 164 deaths in May and none at all in April and March.

China started employing a zero-COVID containment strategy in early 2020 and credits the strict lockdowns, quarantines, border closures and compulsory mass testing with significantly saving lives.

Myanmars prolonged civil strife, tensions in the disputed South China Sea and concern over arms buildups in the region are expected to dominate the agenda when Southeast Asias top diplomats gather for talks this week in Indonesia.

Rescuers in central China are looking for seven people missing in a landslide triggered by torrential rains while employers across much of China have been ordered to limit outdoor work due to scorching temperatures as the country struggles with heat, flooding and drought.

Archeologists are set to begin digging in a central Nebraska field to find the bodies of more than 80 children who were buried at a Native American boarding school.

Congress will consider renewed efforts to shore up voting and election laws in the coming weeks. But in a sign of dissonance between Republicans and Democrats on the basic functions of U.S. democracy, the parties will unveil competing proposals.

But the measures were lifted suddenly in December with little preparation, leading to a final surge in which about 60,000 people died, according to the official toll. Deaths this year peaked in January and February, hitting a high of 4,273 on Jan, 4, but then declined gradually to zero on Feb. 23, according to the Chinese CDC.

Chinese health officials didnt say whether they expect the trend to continue or if they would recommend for preventative measures to be restored.

Two of the deaths in June were from respiratory failure caused by infection, while the CDC said the others involved underlying conditions. Those can include diabetes, heart disease, high blood pressure and other chronic illnesses.

Between Jan. 3, 2020, and July 5, 2023, China reported 99,292,081 confirmed cases of COVID-19 and 121,490 deaths to the World Health Organization.

Experts estimate that many hundreds of thousands of people, perhaps more, may have died in China far higher than the official toll, but still a significantly lower death rate than in the United States and Europe.

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China says 239 people died from COVID-19 in June in a significant ...

Iowa struggling to analyze emerging COVID-19 variants

July 10, 2023

Illustration: Brendan Lynch/Axios

The State Hygienic Laboratory at the University of Iowa is receiving too few positive COVID-19 tests to reliably monitor the virus, making it harder for researchers to detect new strains in recent months.

Why it matters: Keeping track of emerging COVID trends and data can help health officials prevent surges and figure out the most helpful vaccines.

State of play: The state lab at the University of Iowa conducts genome sequencing on positive tests submitted by health facilities around Iowa. Sequencing helps with understanding how the virus is changing, Michael Pentella, director of the lab, tells Axios in an email.

The big picture: Sharing data has also become more difficult nationally after the federal government ended its emergency proclamation against COVID in May, Davida Smyth, a microbiologist at Texas A&M University, tells Axios.

Between the lines: Even if COVID tests in hospitals and doctor's offices are decreasing, Smyth says there's still one universal way of surveilling the virus: wastewater.

Zoom in: The ideal scenario is for states to be able to randomly clinically test populations for COVID-19, in addition to surveilling wastewater.

Whats next: As the public becomes less concerned about COVID, the big concern for the future is finding grants and funding to continue studying these topics and properly testing populations, Smyth says.

Editor's note: This story was corrected to reflect the name of the lab is the State Hygienic Laboratory at the University of Iowa, not the Iowa State Hygienic Lab.

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Iowa struggling to analyze emerging COVID-19 variants

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