Category: Covid-19 Vaccine

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What Covid-19 Vaccine Skeptics Have in Common – The New York Times

April 30, 2021

For years, scientists and doctors have treated vaccine skepticism as a knowledge problem. If patients were hesitant to get vaccinated, the thinking went, they simply needed more information.

But as public health officials now work to convince Americans to get Covid-19 vaccines as quickly as possible, new social science research suggests that a set of deeply held beliefs is at the heart of many peoples resistance, complicating efforts to bring the coronavirus pandemic under control.

The instinct from the medical community was, If only we could educate them, said Dr. Saad Omer, director of the Yale Institute for Global Health, who studies vaccine skepticism. It was patronizing and, as it turns out, not true.

About a third of American adults are still resisting vaccines. Polling shows that Republicans make up a substantial part of that group. Given how deeply the country is divided by politics, it is perhaps not surprising that they have dug in, particularly with a Democrat in the White House. But political polarization is only part of the story.

In recent years, epidemiologists have teamed up with social psychologists to look more deeply into the why behind vaccine hesitancy. They wanted to find out whether there was anything that vaccine skeptics had in common, in order to better understand how to persuade them.

They borrowed a concept from social psychology the idea that a small set of moral intuitions forms the foundations upon which complex moral worldviews are constructed and applied it to their study of vaccine skepticism.

What they discovered was a clear set of psychological traits offering a new lens through which to understand skepticism and potentially new tools for public health officials scrambling to try to persuade people to get vaccinated.

Dr. Omer and a team of scientists found that skeptics were much more likely than nonskeptics to have a highly developed sensitivity for liberty the rights of individuals and to have less deference to those in positions of power.

Skeptics were also twice as likely to care a lot about the purity of their bodies and their minds. They disapprove of things they consider disgusting, and the mind-set defies neat categorization: It could be religious halal or kosher or entirely secular, like people who care deeply about toxins in foods or in the environment.

Scientists have found similar patterns among skeptics in Australia and Israel, and in a broad sample of vaccine-hesitant people in 24 countries in 2018.

At the root are these moral intuitions these gut feelings and they are very strong, said Jeff Huntsinger, a social psychologist at Loyola University Chicago who studies emotion and decision-making and collaborated with Dr. Omers team. Its very hard to override them with facts and information. You cant reason with them in that way.

These qualities tend to predominate among conservatives but they are present among liberals too. They are also present among people with no politics at all.

Kasheem Delesbore, a warehouse worker in northeastern Pennsylvania, is neither conservative nor liberal. He does not consider himself political and has never voted. But he is skeptical of the vaccines along with many institutions of American power.

Mr. Delesbore, 26, has seen information online that a vaccine might harm his body. He is not sure what to make of it. But his faith in God gives him confidence: Whatever happens is Gods will. There is little he can do to influence it. (Manufacturers of the three vaccines approved for emergency use by the Food and Drug Administration say they are safe.)

The vaccines have also raised a fundamental question of power. There are many things in Mr. Delesbores life that he does not control. Not the schedule at the warehouse where he works. Or the way he is treated by the customers at his other job, a Burger King. The decision about whether to get vaccinated, he believes, should be one of them.

April 30, 2021, 12:50 p.m. ET

I have that choice to decide whether I put something in my own body, Mr. Delesbore said. Anybody should.

Mr. Delesbore has had many jobs, most of them through temporary agencies at a park concession stand, at an auto parts warehouse, at a FedEx warehouse, and at a frozen food warehouse. He is sometimes overcome by a sense that he will never be able to get beyond the stress of living paycheck to paycheck. He remembers once breaking down to his parents.

I told them, what am I supposed to do? he said. How are we supposed to make a living? Buy a house and start a family? How?

Like many people interviewed for this article, Mr. Delesbore spends a lot of time online. He is hungry to make sense of the world, but it often seems rigged and it is hard to trust things. He is especially suspicious of how fast the vaccines were developed. He used to work at a factory of the drug company Sanofi, so he knows a bit about the process. He believes there is a lot that Americans are not being told. Vaccines are just one small piece of the picture.

Conspiratorial thinking is another predictor of vaccine hesitancy, according to the 2018 study. Conspiracy theories can be comforting, a way to get ones bearings during rapid change in the culture or the economy, by providing narratives that bring order. They are finding fertile ground because of a decades-long decline in trust in government, and a sharp rise in inequality that has led to a sense, among many Americans, that the government is no longer working on their behalf.

Theres a whole world of secrets and stuff that we dont see in our everyday lives, Mr. Delesbore said. Its politics, its entertainment, its history. Everything is a facade.

The moral preference for liberty and individual rights that the social psychologists found to be common among skeptics has been strengthened by the countrys deepening political polarization. Branden Mirro, a Republican in Nazareth, Pa., has been skeptical of nearly everything concerning the pandemic. He believes that mask requirements impinge on his rights and does not plan to get vaccinated. In fact, he sees the very timing of the virus as suspicious.

This whole thing was a sham, he said. They planned it to cause mass panic and get Trump out of office.

Mr. Mirro, who is 30, grew up in a large Italian-American family in northeastern Pennsylvania. His father owned a landscaping business and later invested in real estate. His mother battled a yearslong addiction to methamphetamine. He said she died this year with fentanyl in her bloodstream.

From an early age, politics was an outlet that brought meaning and importance. He has volunteered for presidential campaigns, watched inaugurations, and gone to rallies for Donald J. Trump. He even went to Washington on Jan. 6, the day of the riot at the U.S. Capitol.

He said that he went because he wanted to stand up for his freedoms, and that he did not go inside the Capitol or support the violence that happened. He also said he believed that Democrats have been hypocritical in how they responded to that event, compared with the unrest in cities last summer following the murder of George Floyd.

Democrats, he said, used to fight for things that were good. He has a picture of John F. Kennedy up on his wall. But they have become dangerous, he said, canceling people and creating racial divisions by what he sees as a relentless emphasis on racial differences.

This isnt the country I grew up in, he said. I have a love for this country, but its turning into something ugly.

Vaccine skeptics are sometimes just as wary of the medical establishment as they are about the government.

Brittany Richey, a tutor in Las Vegas, does not want to get one of the vaccines because she does not trust the drug companies that produced them. She pointed to studies that she said described pharmaceutical companies paying doctors to suppress unfavorable trial results. She keeps a folder on her computer of them.

Ms. Richey said that when she was 19, she was put into a line of girls waiting for the HPV vaccine, which protects against cervical and other cancers, after a routine doctors appointment. She said she did not fully understand what the shot was and why she was being asked to get it.

Thats not informed consent, thats coercion, said Ms. Richey, who is now 33.

Ms. Richey is also worried about the ingredients of the vaccines. She is trying to get pregnant, and she knows that pregnant women were excluded from vaccine trials. She does not want to risk it.

A portion of those who are hesitant will eventually get vaccinated. According to Drew Linzer, the director of the polling firm Civiqs, fewer people are unsure about the vaccines now than in the fall, but the percentage of hard noes has remained fairly constant. As of last week, about 7 percent say they are unsure, he said, and about 24 percent say they will never take it.

Mary Beth Sefton, a retired nurse in Wyoming, Mich., who is a moderate conservative, is not opposed to all vaccines: She usually gets a flu shot. But she worries that the Covid-19 vaccines were developed so quickly that there might be side effects that have not surfaced yet. So she has not gotten a vaccine yet despite being eligible for several months.

Ms. Sefton, who is 73 and describes herself as a person who doesnt like being told what to do, says the politicization of the virus has made it hard to find information she trusts.

The polarization makes it much harder to figure out what is real, she said.

She thinks she might eventually get a vaccine. Her husband is bedridden and she is his primary caregiver. And she would be cut off from some in her family if she remains unvaccinated. But she is nervous.

I still feel exceedingly cautious, she said. It is a basic gut feeling.

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What Covid-19 Vaccine Skeptics Have in Common - The New York Times

Full FDA approval of Covid-19 vaccines could help fight vaccine hesitancy, officials say – CNN

April 30, 2021

These vaccines have been in use since mid-December under emergency use authorizations, known as EUAs. During the pandemic, real-world data have shown the vaccines are effective against the coronavirus that causes Covid-19.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told CNN's Jim Sciutto on Wednesday he hopes Covid-19 vaccines will receive full FDA approval "very soon," and that the FDA will work "as expeditiously as possible" on approval applications for coronavirus vaccines as they come in.

Progressing from authorized to approved would allow manufacturers to market and directly distribute their vaccines. It could also have an impact on vaccine mandates -- and perhaps sway skeptics hesitant to get the vaccines now.

Currently, the three Covid-19 vaccines distributed in the United States -- made by Pfizer/BioNTech, Moderna and Johnson & Johnson -- are authorized, but not approved.

CNN has contacted Pfizer/BioNTech, Moderna and Johnson & Johnson -- the most recent Covid-19 vaccine to be authorized -- about their plans to apply for full approval of their vaccines. None provided a timeline.

The FDA also requires vaccine manufacturers to submit data to support their manufacturing processes, facilities, product characterization and demonstration that the vaccine can be produced reliably and consistently.

Once all of that is complete -- both the clinical trials and manufacturing details -- companies can submit a Biologics License Application or BLA to the FDA.

"FDA evaluates the data to determine whether the safety and effectiveness of the vaccine has been demonstrated and whether the manufacturing and facility information assure product quality and consistency. After its evaluation, FDA decides whether to approve (also known as to license) the vaccine for use in the United States."

After all, as spread of the virus is reduced, the nation may no longer be under an emergency situation and the vaccines will need a different type of green light under the FDA.

The agency is "the gold standard of a safety and regulatory organization throughout the world," said Fauci, chief medical adviser to President Biden. "I hope they do it quickly."

If history is any indication, skepticism -- if not outright mistrust -- about an unapproved vaccine is nothing new.

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Full FDA approval of Covid-19 vaccines could help fight vaccine hesitancy, officials say - CNN

FDA and CDC Lift Recommended Pause on Johnson & Johnson (Janssen) COVID-19 Vaccine Use Following Thorough Safety Review – FDA.gov

April 30, 2021

For Immediate Release: April 23, 2021

Espaol

Following a thorough safety review, including two meetings of the CDCs Advisory Committee on Immunization Practices, the U.S. Food and Drug Administration and the U.S. Centers for Disease Control and Prevention have determined that the recommended pause regarding the use of the Johnson & Johnson (Janssen) COVID-19 Vaccine in the U.S. should be lifted and use of the vaccine should resume.

The pause was recommended after reports of six cases of a rare and severe type of blood clot in individuals following administration of the Janssen COVID-19 Vaccine. During the pause, medical and scientific teams at the FDA and CDC examined available data to assess the risk of thrombosis involving the cerebral venous sinuses, or CVST (large blood vessels in the brain), and other sites in the body (including but not limited to the large blood vessels of the abdomen and the veins of the legs) along with thrombocytopenia, or low blood platelet counts. The teams at FDA and CDC also conducted extensive outreach to providers and clinicians to ensure they were made aware of the potential for these adverse events and could properly manage and recognize these events due to the unique treatment required for these blood clots and low platelets, also known as thrombosis-thrombocytopenia syndrome (TTS).

The two agencies have determined the following:

CDCs independent Advisory Committee on Immunization Practices met today to discuss the latest data on TTS, hearing from the vaccine manufacturer Janssen and the COVID-19 Vaccine Safety Technical (VaST) Subgroup, as well as a risk benefit analysis. ACIP is committed to be vigilant and responsive to additional information that could impact the risk benefit analysis of any of these vaccines. Vaccine safety monitoring will continue and any new information about TTS will be brought to ACIP as needed.

Safety is our top priority. This pause was an example of our extensive safety monitoring working as they were designed to workidentifying even these small number of cases. Weve lifted the pause based on the FDA and CDCs review of all available data and in consultation with medical experts and based on recommendations from the CDCs Advisory Committee on Immunization Practices. We have concluded that the known and potential benefits of the Janssen COVID-19 Vaccine outweigh its known and potential risks in individuals 18 years of age and older. We are confident that this vaccine continues to meet our standards for safety, effectiveness and quality. We recommend people with questions about which vaccine is right for them have those discussions with their health care provider, said Janet Woodcock, M.D., Acting FDA Commissioner.

Above all else, health and safety are at the forefront of our decisions, said CDC Director Dr. Rochelle P. Walensky. Our vaccine safety systems are working. We identified exceptionally rare events out of millions of doses of the Janssen COVID-19 administered and we paused to examine them more carefully. As we always do, we will continue to watch all signals closely as more Americans are vaccinated. I continue to be encouraged by the growing body of real-world evidence that the authorized COVID-19 vaccines are safe and effective, and they protect people from disease, hospitalization, and death. I urge anyone with questions about the COVID-19 vaccines to speak with their healthcare provider or local public health department.

Assessment of Available Data

Medical and scientific teams at the FDA and CDC reviewed several sources of information and data related to the Janssen COVID-19 Vaccine to reach todays decision.

Specifically, the agencies assessed reports submitted to the Vaccine Adverse Event Reporting System (VAERS), reviewed the medical literature and considered the information from global regulatory partners about thrombosis with thrombocytopenia that have been reported following use of a similar, yet not identical, COVID-19 vaccine using a virus from the adenovirus family that has been modified to contain the gene for making a protein from SARS-CoV-2.

Update on Adverse Events

On April 13, the FDA and CDC announced that, out of more than 6.8 million doses administered, six reports of a rare and severe type of blood clot combined with low blood platelet levels occurring in people after receiving the Janssen COVID-19 Vaccine had been reported to VAERS. In these cases, a type of blood clot called cerebral venous sinus thrombosis (CVST) was seen in combination with low levels of blood platelets (thrombocytopenia).

Today, the agencies can confirm that a total of 15 cases of TTS have been reported to VAERS, including the original six reported cases. All of these cases occurred in women between the ages of 18 and 59, with a median age of 37 years. Reports indicated symptom onset between 6 and 15 days after vaccination.

Monitoring for Safety Will Continue

The surveillance systems that are in place to monitor the safety of COVID-19 vaccines authorized for emergency use are working, as demonstrated by both agencies quick work to identify and investigate these rare, but serious adverse events. The FDA and CDC will continue with these efforts to closely monitor the safety of these vaccines.

Reports of adverse events following vaccination can be made to the Vaccine Adverse Event Reporting System.

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The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nations food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

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FDA and CDC Lift Recommended Pause on Johnson & Johnson (Janssen) COVID-19 Vaccine Use Following Thorough Safety Review - FDA.gov

COVID-19 vaccines and the LGBTQ+ community – Harvard Health Blog – Harvard Health

April 30, 2021

I have a confession: in late 2020, when the first COVID-19 vaccines were approved by the FDA, I was hesitant to get one myself. Despite working in public health and believing strongly in vaccines to keep our community healthy, I was anxious about putting something in my body that seemed so new. I thought: What if the vaccine is dangerous? What about long-term side effects?

I am part of the LGBTQ+ community. Our history may help explain why I hesitated.

In March a New York Times article reported that LGBTQ+ people are more hesitant to get the COVID-19 vaccine. A research study from the Human Rights Campaign reported mixed findings: while LGBTQ+ people overall are more likely to get vaccinated, certain subgroups, such as LGBTQ+ people of color and bisexual women, are less likely to get vaccinated.

LGBTQ+ people have good reason to be hesitant about vaccines. Historically, this population has experienced and continues to experience discrimination in multiple settings, including in healthcare. At the same time, this population is more vulnerable to COVID-19 (see this study and an earlier blog post I wrote). LGBTQ+ people who are also people of color may be even more hesitant to get the COVID-19 vaccine, because of trauma and oppressions based on multiple intersecting marginalized identities that set the stage for mistrust in healthcare and medical research. We can include racism, transphobia, biphobia, and homophobia among such oppressions.

When I was trying to decide whether to get the vaccine, I began reading about the vaccine from trusted sources like the Centers for Disease Control and Prevention (CDC). I also talked to people I know and trust, like close friends, family members, and physician colleagues. I asked them: Will you get the vaccine when its offered to you? All of them gave me a resounding yes! Most shared this rationale: while we still dont know about long-term side effects, this vaccine is similar to other vaccines that have been around for a while, and the benefits of getting vaccinated far outweigh the risks of getting seriously ill or even dying from COVID-19.

When the vaccine was offered to me earlier this year, I booked my appointment immediately, without hesitation, and I havent looked back. As soon as I got the first shot, and certainly when I was fully vaccinated two weeks after my second shot, I felt a profound sense of relief. I also felt empowered about taking an important step toward keeping myself, my family, and my community safe from COVID-19. I now feel safer and freer in my daily life. I go into stores (wearing a mask) without feeling anxious, and I have been able to visit in-person with other fully vaccinated people, like my mom, without masks.

Numerous pandemics have already wiped out large numbers of the LGBTQ+ community: HIV/AIDS, violence, suicide. In addition, the COVID-19 pandemic has already disproportionately harmed LGBTQ+ people (see this study and this report). LGBTQ+ seniors and people of color are at greatest risk for serious, possibly life-threatening illness from COVID-19. If each of us takes steps to get vaccinated, we can prevent more deaths and negative health outcomes in our communities.

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COVID-19 vaccines and the LGBTQ+ community - Harvard Health Blog - Harvard Health

Covid-19 Vaccine, Variants and Cases: Live Updates – The New York Times

April 30, 2021

Heres what you need to know:The Narendra Modi Stadium in Ahmedabad, India, last month.Credit...Danish Siddiqui/Reuters

As plumes of smoke rose from cremation grounds, where bodies were arriving faster than they could be burned, teams of professional cricket players squared off under the lights of a cavernous stadium named for Indias prime minister, Narendra Modi.

The jarring scenes unfolded on Thursday in Ahmedabad, the capital of Mr. Modis home state of Gujarat and a hot spot in Indias spiraling coronavirus outbreak, which is claiming an average of nearly 3,000 lives a day nationwide.

For decades, cricket and its charismatic stars have commanded exalted status in India, where the once-genteel colonial game attracts its biggest and most passionate fan base. Now, public anger is growing at the sports marquee international product, the Indian Premier League, which is playing matches in a bio-bubble without spectators that has drawn criticism for diverting resources from the countrys wider coronavirus fight.

There is a lack of empathy for dead bodies lying in crematoriums surrounding your stadium, said Rahul Verma, a lawyer and die-hard cricket fan who said he had been a devoted follower of the cricket league since it started in 2008. This game, a gentlemans game, never was so grotesque.

India set another global record on Friday with nearly 383,000 new infections, the health ministry reported, pushing the global coronavirus case count to more than 150 million.

In India, with one in five tests coming back positive, experts fear the true toll is much higher. As the U.S. Air Force delivered the first shipments of oxygen cylinders, test kits, masks and other emergency supplies promised to India by the Biden administration, several Indian states said they could not fulfill the governments directive to expand vaccinations to all adults beginning on Saturday because they lacked vaccine doses.

As hospitals face shortages of intensive-care beds, relatives of the sick broadcast desperate pleas on social media for oxygen, medicine and other scarce supplies. Many Indians say they do not know if they are infected with the coronavirus because overwhelmed labs have stopped processing tests.

But one group that seems unaffected is the wealthy and powerful Board of Control for Cricket in India, the regulatory body that oversees the Indian Premier League, which was modeled on soccers Premier League in England and features players from around the world.

The board has kept ambulances fitted with mobile intensive-care beds on standby outside stadiums where matches are being played in case a player falls sick. It is testing players every two days and has created a travel bubble between stadiums in the six states hosting matches, including dedicated airport check-in counters for cricketers.

Meanwhile, some Indians say they cannot cross state lines to find hospital beds for Covid-19 patients.

Hemang Amin, the boards chief operating officer, said in a letter released this week that the health and safety of players and staff members were of paramount importance, and added that the matches, which conclude on May 30, were a needed distraction in a difficult time.

When you all walk out onto the field, you are bringing hope to millions of people who have tuned in, he wrote.

But the leagues safety protocols have only highlighted the gap between its star players who have said little publicly in the face of criticism and the rest of the country.

That ambulance outside that stadium could have saved at least ten lives a day, said Ishan Singh, a cricket fan in Delhi. These players are thieves. Given a chance, they will rob wood from the cremations and sell it in the market.

The New Indian Express, a daily newspaper, said in an editorial this week that it would suspend coverage of the cricket league until a semblance of normalcy is restored in the country.

This is commercialism gone crass, the newspaper wrote. The problem is not with the game but its timing.

The vaccine developed by AstraZeneca and the University of Oxford brought in $275 million in sales from about 68 million doses delivered in the first three months of this year, AstraZeneca reported on Friday.

AstraZeneca disclosed the figure, most of which came from sales in Europe, as it reported its first-quarter financial results. It offers the clearest view to date of how much money is being brought in by one of the leading Covid vaccines.

AstraZeneca, which has pledged not to profit on its vaccine during the pandemic, has been selling the shot to governments for several dollars per dose, less expensive than the other leading vaccines. The vaccine has won authorization in at least 78 countries since December but is not approved for use in the United States.

The vaccine represented just under 4 percent of AstraZenecas revenue for the quarter; it was nowhere near the companys biggest revenue generator. By comparison, the companys best-selling product, the cancer drug Tagrisso, brought in more than $1.1 billion in sales in the quarter.

AstraZeneca has said it is planning to seek emergency authorization for its vaccine to be used in the United States, even as it has become clear that the doses are not needed. The Biden administration said this week that it would make available to the rest of the world up to 60 million doses of its supply of AstraZeneca shots, pending a review of their quality.

If the company does win authorization from the U.S. Food and Drug Administration, it could help shore up confidence in a vaccine whose reputation been hit by concerns about a rare but serious side effect involving blood clotting. The F.D.A.s evaluation process is considered the gold standard globally.

Johnson & Johnson, whose vaccine was authorized for emergency use at the end of February, reported last week that its vaccine generated $100 million in sales in the United States in the first three months of the year. The federal government is paying the company $10 a dose. Like AstraZeneca, Johnson & Johnson has pledged to sell its vaccine at cost meaning it wont profit on the sales during the pandemic.

Vaccines from Pfizer and Moderna cost more, and neither company has said that it will forego profits. Pfizer has said that it expects its vaccine to bring in about $15 billion in revenue this year; Moderna said it anticipates $18.4 billion in sales.

Both companies are scheduled to report their first-quarter results next week.

Executives of Emergent BioSolutions, the vaccine manufacturer that was forced to discard up to 15 million doses because of possible contamination, reported a shake-up in leadership on Thursday and offered the most fulsome defense yet of the companys performance.

While announcing the high-level personnel changes and taking responsibility for the ruined doses, executives nonetheless forecast record revenues this year of nearly $2 billion.

Robert Kramer, the chief executive, speaking on a call with investors, said that one senior vice president overseeing manufacturing would depart the company while another executive would go on leave. A third official, Mary Oates, who recently joined Emergent after a long tenure at Pfizer, is now leading the companys response to a recent federal inspection that found serious flaws at the Baltimore facility that produced the vaccines.

The call on Thursday came at a tumultuous time for Emergent, a once-obscure federal contractor that has built a lucrative business selling biodefense products to the government. Production at the companys Baltimore plant was suspended this month after the discovery that workers had potentially contaminated millions of doses of the Johnson & Johnson vaccine.

Addressing these setbacks, Mr. Kramer offered a vigorous defense of the company on Thursday.

He took full responsibility for the manufacturing problems, acknowledging that the loss of a batch for a viral contamination is extremely serious, and we treated it as such, but he also said that Emergent had taken on a herculean task in a crisis.

GREENVILLE, TENN. This community and its surroundings in northern Tennessee are rural, overwhelmingly Republican, deeply Christian and 95 percent white. Polls show that resistance to the vaccine is most entrenched in such areas.

While campaigns aimed at convincing Black and Latino urban communities to set aside their vaccine mistrust have made striking gains, towns like Greenville will also have to be convinced, if the country is to achieve widespread immunity.

But a week here in Greene County reveals a more nuanced, layered hesitancy than surveys suggest. People say that politics isnt the leading driver of their vaccine attitudes. The most common reason for their apprehension is fear that the vaccine was developed in haste, that long-term side effects are unknown. Their decisions are also entangled in a web of views about bodily autonomy, science and authority, plus a powerful regional, somewhat romanticized self-image: We dont like outsiders messing in our business.

Still, conversations here show that for many people, resistance is not firm. Roiled by internet fallacies, many hunger for straightforward information from people they trust. Others have practical needs, like paid time off to recover from side effects, which the Biden administration has urged employers to offer, or the opportunity to get the shot from their own doctor.

GLOBAL ROUNDUP

Thousands of people letting loose on a nightclub dance floor. Hundreds of suited-up people gathering for a business conference. And none of them wearing masks.

As Britain slowly emerges from a lengthy lockdown, a flashback to life before the pandemic is taking place in Liverpool as part of a series of government-led experiments.

Liverpool on Wednesday hosted Britains first business conference since March 2020 and the northwestern English city will on Friday kick off a two-day nightclub event, the first in Britain in more than a year, and an outdoor music festival will take place on Sunday.

The events are part of a British government research project to see how mass gatherings can happen safely. Participants are asked to take a coronavirus test before events and are required to produce a negative result. Once they are inside the venues, social distancing and face coverings are not required.

The pilot events are taking place across England this month and next month, closely monitored by the health authorities. Some sports competitions with audiences have already been part of the program and thousands of people will gather in London next month for the Brit Awards music show, and soccers F.A. Cup final.

Every attendee will be asked to undergo a virus test after the event and the research gathered will shape the governments policy on bringing back large events.

England has set a provisional date of June 21 for all of its virus restrictions to be dropped, including those on mass gatherings, and scientists are hoping that the events that they are monitoring will provide insights into how to reduce the risk of the virus spreading.

Britain has in recent days reported its lowest number of infections since September and has given a first dose of a coronavirus vaccine to more than half its population.

In other updates from around the world:

Authorities at tollbooths and ports in Greece on Friday have turned back hundreds of people attempting to defy virus restrictions on travel between regions ahead of Orthodox Easter, the most important date in the religious calendar. Although cases have stabilized in recent weeks, deaths and hospitalizations remain high. Greece has gradually lifted restrictions in recent weeks, including ending quarantine requirements for visitors from dozens of countries, as it prepares to fully reopen its tourism sector next month.

While Spain is expected to lift its nationwide state of emergency on May 9, allowing for the return of tourists in June, some regional administrations are preparing to extend their own lockdown measures for longer. Cases are down, and more people are getting vaccinated. Reopening tourism is key to the economy, which contracted in the first quarter, the government said on Friday. Tourism arrivals dropped to 19 million last year, after seven years of growth, from 84 million in 2019.

In Portugal, Prime Minister Antnio Costa announced late Thursday that the countrys only land border with Spain would reopen on Saturday, having remained shut since January. Portugal is also fast-tracking the removal of lockdown restrictions after reducing significantly its coronavirus infection rate.

Raphael Minder and Niki Kitsantonis contributed reporting.

Before the pandemic, Googles sprawling campus of airy, open offices and whimsical common spaces set a standard for what an innovative workplace was supposed to look like.

Now, the company is creating a workplace for the Covid era, with a concept perhaps best described as Ikea meets Lego.

Instead of rows of desks next to cookie-cutter meeting rooms, Google is designing Team Pods. Chairs, desks, whiteboards and storage units on casters can be wheeled into various arrangements, and in some cases rearranged in a matter of hours. It is building outdoor work areas to respond to concerns about the coronavirus.

At its Silicon Valley headquarters, it has converted a parking lot and lawn area into a camp, with clusters of tables and chairs under open-air tents. The area is a fenced-in mix of grass and wooden deck flooring about the size of four tennis courts with Wi-Fi throughout.

David Radcliffe, Googles vice president for real estate and workplace services, said that while moving more than 100,000 employees to virtual work last year was daunting, now it seems even more daunting to figure out how to bring them back safely.

With vaccinations mounting in some of the worlds wealthiest countries and people envisioning life after the pandemic, the crisis in Latin America is taking an alarming turn for the worse, potentially threatening the progress made well beyond its borders.

Last week, Latin America accounted for 35 percent of all coronavirus deaths in the world, despite having just 8 percent of the global population, according to data compiled by The New York Times.

The length of the regions epidemic makes it even harder to fight. It has already endured some of the strictest lockdowns, longest schools closures and largest economic contractions in the world.

And if Latin America fails to contain the virus or if the world fails to step in to help it new, more dangerous variants may emerge, said Dr. Jarbas Barbosa of the Pan-American Health Organization.

This could cost us all that the world is doing to fight the pandemic, he said.

After being closed for more than a year, Disneyland reopens on Friday to California residents only. Travel advisers around the country said tickets sold out quickly, and people have been waiting online for hours to get a reservation to the Anaheim, Calif., theme park.

As more people across the United States are vaccinated and as summer approaches, theme park bookings are picking up, even though children are still not eligible for coronavirus vaccines. Greg Antonelle, the chief executive of MickeyTravels, a travel agency that helps plan Disney trips, said that if bookings keep up at the current pace, this will be the companys strongest year.

Walt Disney World in Orlando, Fla., opened in July and is operating at 35 percent capacity. At Disneyland, capacity is now capped at 25 percent, and officials have not said when restrictions would be eased or bookings would be opened to out-of-state visitors.

Getting in requires both a ticket and a reservation to the park. Park rules state that masks must be worn at all times, except when swimming or eating, even by those who have been vaccinated. The parades, fireworks, and nighttime spectaculars that are typical of the Disney park experience are still suspended, and character interactions are socially distanced.

But for Bethany Millar, an administrator at a medical school in St. Louis who visited Walt Disney World in April, it was worth it: Disneys staff did everything in their power to make you feel like you were having a safe Covid experience, she said.

A daughter holding her mothers hand. A son overcome that his 95-year-old mother had survived the pandemic. A stoic family patriarch, suddenly in tears.

After a year of excruciating lockdowns, these were the scenes at nursing homes and other long-term care facilities as they began to open up this spring. Before the arrival of vaccines, one in three coronavirus deaths in the United States had ties to nursing homes or similar facilities.

The New York Times sent photographers across the country to document reunions. For many family members, it was the first time they were able to be together, hold hands and hug in more than a year.

In interviews, which have been edited and condensed for clarity, families recalled a deep fear that they would never see their loved ones again. When the time finally came, they were flooded with a years worth of emotion in a single instant: joy, relief, love and grief for all the time that had been lost.

Con Yan Muy, 93, has been a resident at the San Francisco Campus for Jewish Living nursing home since 2019. Anita Li, 24, grew up with her grandmother and previously visited daily. For a year during the pandemic, she saw her grandmother only a handful of times through a window or at a distance. Even now, her visits remain limited, as is the case at many facilities.

ANITA LI: I was hiding in the bathroom when she came in. It was a surprise. She didnt recognize me initially because I had my mask on. I am going to be honest, I was kind of sad. I am one of the most involved persons in her life, and she couldnt recognize me. I immediately just started patting her legs and her arms for better blood circulation. I had brought some dumplings and also brought her some sesame balls that she really enjoys. We made a video for the rest of the family for her to say hi.

Its like a sigh of relief that we could finally be together, but also knowing that this was a one-time thing, and not really sure what the future holds. Am I going to see her every week face to face? Can I eventually take her out on walks where she can get some sun? What is the new normal, and how much can we be involved in her life postquarantine?

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Covid-19 Vaccine, Variants and Cases: Live Updates - The New York Times

Dallas mayor will host pop-up COVID-19 vaccination events starting Friday – The Dallas Morning News

April 30, 2021

In the latest effort to increase COVID-19 vaccine access in underserved communities, Dallas Mayor Eric Johnson is partnering with private providers to distribute doses.

Johnson announced the creation of the Neighborhood Vaccine Initiative Thursday. The initiative, which is separate from the city of Dallas efforts, will kick off with three upcoming pop-up vaccination events across Southern and West Dallas.

Johnson and the Caring Foundation of Texas will co-host the first event Friday at the Bishop Arts Theatre Center, 215 S. Tyler St., starting at 10 a.m.

The second will be Saturday at Pinkston High School, 2200 Dennison St., at 10 a.m. The third will be Tuesday at the Jubilee Park Community Center, 907 Bank St., at 1 p.m.

This is not the first time Johnson and the organization have worked together the two partnered to co-host a vaccination clinic at South Oak Cliff High School earlier in April.

It has never been easier to get a COVID-19 vaccine in Dallas, Johnson said in a press release. But we are still working hard to eliminate all remaining barriers to receiving these lifesaving vaccines.

Johnson said Dallas residents should get vaccinated when they have the opportunity to help the city reach herd immunity and end the pandemic.

People who would like to attend one of the pop-up vaccine events can register online. Find registration information about the Jubilee Park clinic here and the Pinkston event here.

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Dallas mayor will host pop-up COVID-19 vaccination events starting Friday - The Dallas Morning News

Hackers are attacking the COVID-19 vaccine supply chain – CBS News

April 30, 2021

Hackers have targeted companies that distribute the COVID-19 vaccine to a degree previously unreported, according to research from IBM Security.

Starting last year, attackers attempted to access sensitive information about the vaccine's "cold chain" distribution system. IBM Security said the phishing attack targeted 44 companies in 14 countries across Europe, North America, South America and Asia.It is unclear if the hackers were successful in breaching systems. The hacking victims include high-ranking executives at a petrochemical firm, a solar energy manufacturer, several IT companies and a department at the European Commission.

The cyberattack was first discovered in late 2020. Researchers initially believed the hacking campaign targeted theGAVI alliance, a coalition of governments and companies that help developing countries distribute vaccines. At the time, it was unclear if the campaign was successful, according to IBM's global lead for threat intelligence, Nick Rossmann.

But the new IBM research shows the operation's scope was larger than previously thought, requiring significant "premeditated planning," Rossmann said. "This was a very well-calibrated, complex and precise campaign."

Although his team cannot conclusively attribute the cyberattack to a particular actor, Rossmann said "this operation has the hallmarks of nation-state activity. We're dealing with an adversary [that] has an acute understanding of [the vaccine] supply chain."

The ability to disrupt or destroy vaccine supplies amount to a form of saber-rattling, Rossmann said.

"We're far from over the COVID-19 crisis, and while the U.S. has turned the corner with its vaccination progress, many other countries continue to face significant challenges. As countries struggle to get access to vaccines, this type of adversarial activity illustrates a race for influence over the vaccine market," he said.

A range of health care firms were major targets of the hacking scheme. That includes biomedical research organizations, medical equipment manufacturers; pharmaceutical firms, surgical material makers, immunology experts and pharmacies distributing COVID-19 rapid tests.

Logistics and transportation were also heavily targeted in the cyberattack, including eight companies in the automotive, aviation, maritime and transport services sectors across Italy, Korea, Japan, Colombia and the U.S.

"Logistics firms are a particularly ripe target," Rossmann said. "They are moving the vaccine in different places around the world. You can imagine that a refrigeration company probably doesn't have the same security as one of the largest banks in the world."

This hacking group was capable of surreptitiously mining large amounts of data about how the vaccine is shipped, or even shutting down the company's operational systems. "Potentially [hackers] could spoil the vaccine batches that they have in refrigeration units," he said.

The attack was carried out in multiple stages. The hackers used highly customized spear-phishing emails to target companies in the cold chain. Phishing hacks are emails or text messages that appear to be sent from a legitimate source and are intended to steal a victim's username and password. Most phishing attacks, like spam, are imprecise and sent to thousands of recipients.

The cold chain hackers devised a clever cover story: They impersonated an employee of Haier Biomedical, one of the world's most respected cold chain providers and a client of one of the first targets.

Those targets were CEOs, product managers, sales managers and finance executives who anticipated an email requesting approval. The phishing message they received was so well-crafted that at least some of its recipients fell for the scam, Rossman said.

"The quote generally looked very good! And when you clicked on this email, a PDF popped up with a, 'Hey, can you please write your username, your password,' not typical for a PDF you would get from a supplier," Rossmann said.

Once inside the network, the hackers were able to steal important credential information, move to other parts of the network and send additional phishing messages by posing as executives from the company.

Harvested credentials are also often used to gain future unauthorized access to corporate networks and sensitive information. Researchers eventually discovered an additional 50 similar messages targeting the cold chain companies.

COVID-19 presented a huge opportunity for a wide spectrum of cybercriminals and malicious actors. The Department of Health and Human Services last month issued a phishing alert, warning: "Fraudsters are offering COVID-19 tests, HHS grants, and Medicare prescription cards in exchange for personal details, including Medicare information."

Email scams in particular are surging, according to the cyber defense firm Barracuda. A Verizon report last year found that phishing was responsible for almost 70% of data breaches.

"Cold chain companies are a piece of critical infrastructure and they're under attack," Rossmann said, noting that damaging these firms poses a major risk to public safety and national security.

The hackers' attempt to disrupt or destroy vaccine supplies was likely intended to undermine trust in the treatments, he said. If even a small percentage of COVID-19 vaccine doses were damaged, it could weaken trust in the entire system.

"This threat is very real, and our goal is to make sure anyone involved in any aspect of the supply chain is on high alert," Rossman said. "In the United States, Canada and Europe, where there is already doubt [about vaccine safety], sowing mistrust is a part of the arsenal of what some of these adversaries do."

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Hackers are attacking the COVID-19 vaccine supply chain - CBS News

Michigan unveils reopening plan tied to COVID-19 vaccination rates – ABC News

April 30, 2021

Michigan Gov. Gretchen Whitmer unveiled a reopening plan Thursday that will tie loosened restrictions to COVID-19 vaccination rate milestones, as the state starts to emerge from a surge in cases and hospitalizations.

So far, nearly half of residents ages 16 and up have gotten their first shots and about 36% are fully vaccinated, said the governor, whose goal is to reach 70% of the population fully vaccinated to near herd immunity.

Michigan will likely reach 55% of residents ages 16 and up receiving a first dose by the end of next week, Whitmer said. Two weeks after it hits that benchmark, under the new plan, in-person work for all businesses will be allowed.

Two weeks after 60% have gotten their first dose, sports stadiums and banquet halls can increase capacity to 25%, gyms can go up to 50% and an 11 p.m. curfew on indoor dining will be lifted.

Two weeks after hitting 65%, all indoor capacity limits will be lifted, and two weeks after reaching 70% -- about 5.6 million residents ages 16 and up -- the state's order on masks and gatherings will end.

"The vaccine remains the most effective way to protect you and your family from COVID and help us all return to normal sooner," Whitmer said at a press briefing Thursday. "We can all see the light at the end of the tunnel. ... But I want to remind you, we're still in the tunnel, and we have a lot of work to do."

Michigan had previously resisted tying its reopening to certain metrics, but now considers vaccines the "best tool that we have to get back to normal," the governor said.

"This is a creative way of challenging us to rise to this moment and to meet it," Whitmer said.

Second-year Michigan State University graduate student Genevieve Gottardo gets her Pfizer COVID-19 vaccination shot on April 14, 2021, at the student vaccination clinic at the MSU Pavilion in East Lansing, Mich.

She said it's a "real possibility" that Michigan could have normal gatherings by the Fourth of July, a goal previously stated by President Joe Biden.

The vaccination plan was welcomed by several Michigan business associations, including the Michigan Restaurant & Lodging Association.

"We applaud the governor for implementing what the MRLA has been requesting for months -- a metric driven plan that offers incentives rather than mandates to drive better outcomes and more opportunity for the imperiled hospitality industry," Justin Winslow, president of the association, said in a statement.

Dr. Ashish K. Jha, dean of the Brown School of Public Health, called the plan a "really innovative, smart strategy to tie loosening of public health restrictions to vaccination rates in Michigan."

"[Let's] hope this motivates folks to get the shot," he said on Twitter.

The vaccination plan comes as Michigan is starting to turn the corner on a surge in cases and hospitalizations, particularly among young adults. Health experts attributed the surge to the spread of more transmissible variants and a lack of mask and social distancing compliance.

A group of people walk wearing protective masks head to a restaurant as COVID-19 restrictions are eased in Ann Arbor, Mich., on April 4, 2021.

Centers for Disease Control and Prevention Director Dr. Rochelle Walensky said earlier this month that Michigan couldn't vaccinate its way out of its COVID-19 surge and needed to "close things down."

Other medical experts argued that vaccine supply should be ramped up to COVID-19 hotspots.

Michigan didn't issue any new restrictions, though Whitmer advised residents to avoid indoor dining and recommended a two-week pause on in-person learning for high schools and sports activities.

"Our seven-day case averages, hospitalizations and ICU numbers are all coming down," Whitmer said Thursday. "While the daily case count, test positivity and hospitalization numbers are still not where we want them to be, we're headed in the right direction."

The Michigan health department's latest weekly report, released Tuesday, showed that in the past week, new COVID-19 cases decreased 14%, COVID-19 hospitalizations dropped 16% and the testing positivity rate was down 14%. Still, the state has the highest seven-day case rate per 100,000 in the country, according to the CDC.

Originally posted here:

Michigan unveils reopening plan tied to COVID-19 vaccination rates - ABC News

The latest on Covid-19 and India’s worsening crisis: Live updates – CNN

April 30, 2021

Indian Prime Minister Narendra Modi called for people to continue to come out "in line with Covid-19 protocols" and vote during the last phase of West Bengal state elections.

Modi and hisBharatiya Janata Party(BJP) have come under fire for holding several rallies ahead of the elections in West Bengal, with thousands in attendance and failing to abide by social distancing guidelines.

Critics have accused the BJP of putting politics before public health. India is now facing a massive new wave of Covid-19 cases across the country and nationwide shortages of oxygen.

On April 22, the Election Commission of India tightened restrictions for the remaining phases of the West Bengal state assembly elections, banning road shows, vehicle rallies and large public meetings with more than 500 people after finding political parties and candidates were flouting Covid-19 guidelines.

However, political parties including the BJP continued to hold rallies throughout the week, even as India continued to record more than 300,000 cases per day.

Thursday is the last day of voting in West Bengal. The polls opened around7 a.m. local time (9:30p ET) and are expected to close at 6:30 p.m. local (9a ET).

Southern Tamil Nadu and Kerala states, West Bengal and Assam states in the east and the union territory of Puducherry went to the polls on March 27, with voting taking place across eight phases and ending on April 29. All votes are to be counted on May 2, with the results announced on the same day, though Indias Election Commission has banned victory procession.

On Thursday, the Election Commission also issued guidelines ordering all polling officials and candidates to provide negative Covid-19 test reports or to have had both doses of Covid-19 vaccine ahead of May 2.

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The latest on Covid-19 and India's worsening crisis: Live updates - CNN

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