Category: Covid-19 Vaccine

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20 counties with the highest COVID-19 vaccination rate in California – KTLA

November 21, 2021

As has been true throughout Americas COVID-19 history, every stateand every county thereinhas its own COVID-19 story, driven by local policies and behaviors. The United States as of Nov. 19 had reached 768,836 COVID-19-related deaths and nearly 47.5 million COVID-19 cases,according to Johns Hopkins University.

As of Feb. 2,more Americans had been vaccinated for COVID-19 than had been infected,and though breakthrough infections are continuing to be studied by the CDC and other health organizations, vaccines have reduced the number of hospitalizations and deaths from COVID-19.

Stackercompiled a list of the counties with highest COVID-19 vaccination rates in California using data from theU.S. Department of Health & Human Services. Counties are ranked by the highest vaccination rate as of Nov. 18, 2021.

Keep reading to see whether your county ranks among the highest COVID-19 vaccination rates in the state.

Population that is fully vaccinated: 59.2% (80,314 fully vaccinated) 5.1% lower vaccination rate than California

Population over 65 that is fully vaccinated: 84.6% (21,313 fully vaccinated) 0.1% higher vaccination rate than California

Cumulative deaths per 100k: 86 (117 total deaths) 53.3% less deaths per 100k residents than California

Cumulative cases per 100k: 7,283 (9,873 total cases) 42.5% less cases per 100k residents than California

Population that is fully vaccinated: 59.3% (920,304 fully vaccinated) 5.0% lower vaccination rate than California

Population over 65 that is fully vaccinated: 86.7% (194,922 fully vaccinated) 2.6% higher vaccination rate than California

Cumulative deaths per 100k: 154 (2,394 total deaths) 16.3% less deaths per 100k residents than California

Cumulative cases per 100k: 10,702 (166,101 total cases) 15.5% less cases per 100k residents than California

Population that is fully vaccinated: 60.3% (240,104 fully vaccinated) 3.4% lower vaccination rate than California

Population over 65 that is fully vaccinated: 86.8% (68,906 fully vaccinated) 2.7% higher vaccination rate than California

Cumulative deaths per 100k: 115 (459 total deaths) 37.5% less deaths per 100k residents than California

Cumulative cases per 100k: 10,417 (41,494 total cases) 17.7% less cases per 100k residents than California

Population that is fully vaccinated: 61.1% (52,995 fully vaccinated) 2.1% lower vaccination rate than California

Population over 65 that is fully vaccinated: 82.5% (16,519 fully vaccinated) 2.4% lower vaccination rate than California

Cumulative deaths per 100k: 108 (94 total deaths) 41.3% less deaths per 100k residents than California

Cumulative cases per 100k: 9,582 (8,312 total cases) 24.3% less cases per 100k residents than California

Population that is fully vaccinated: 61.5% (266,733 fully vaccinated) 1.4% lower vaccination rate than California

Population over 65 that is fully vaccinated: 81.7% (49,638 fully vaccinated) 3.3% lower vaccination rate than California

Cumulative deaths per 100k: 140 (609 total deaths) 23.9% less deaths per 100k residents than California

Cumulative cases per 100k: 11,980 (51,999 total cases) 5.4% less cases per 100k residents than California

Population that is fully vaccinated: 61.6% (135,723 fully vaccinated) 1.3% lower vaccination rate than California

Population over 65 that is fully vaccinated: 92.1% (26,270 fully vaccinated) 9.0% higher vaccination rate than California

Cumulative deaths per 100k: 117 (257 total deaths) 36.4% less deaths per 100k residents than California

Cumulative cases per 100k: 9,649 (21,276 total cases) 23.8% less cases per 100k residents than California

14. Santa Barbara County

Population that is fully vaccinated: 62.8% (280,355 fully vaccinated) 0.6% higher vaccination rate than California

Population over 65 that is fully vaccinated: 87.2% (61,148 fully vaccinated) 3.2% higher vaccination rate than California

Cumulative deaths per 100k: 121 (539 total deaths) 34.2% less deaths per 100k residents than California

Cumulative cases per 100k: 10,445 (46,639 total cases) 17.5% less cases per 100k residents than California

13. Los Angeles County

Population that is fully vaccinated: 63.2% (6,344,786 fully vaccinated) 1.3% higher vaccination rate than California

Population over 65 that is fully vaccinated: 80.7% (1,140,463 fully vaccinated) 4.5% lower vaccination rate than California

Cumulative deaths per 100k: 268 (26,923 total deaths) 45.7% more deaths per 100k residents than California

Cumulative cases per 100k: 15,084 (1,514,282 total cases) 19.2% more cases per 100k residents than California

12. Orange County

Population that is fully vaccinated: 64.2% (2,038,620 fully vaccinated) 2.9% higher vaccination rate than California

Population over 65 that is fully vaccinated: 86.0% (417,743 fully vaccinated) 1.8% higher vaccination rate than California

Cumulative deaths per 100k: 178 (5,653 total deaths) 3.3% less deaths per 100k residents than California

Cumulative cases per 100k: 10,433 (331,322 total cases) 17.6% less cases per 100k residents than California

Population that is fully vaccinated: 64.3% (543,621 fully vaccinated) 3.0% higher vaccination rate than California

Population over 65 that is fully vaccinated: 88.2% (120,568 fully vaccinated) 4.4% higher vaccination rate than California

Cumulative deaths per 100k: 140 (1,183 total deaths) 23.9% less deaths per 100k residents than California

Cumulative cases per 100k: 12,197 (103,187 total cases) 3.6% less cases per 100k residents than California

Population that is fully vaccinated: 68.9% (94,843 fully vaccinated) 10.4% higher vaccination rate than California

Population over 65 that is fully vaccinated: 87.7% (23,825 fully vaccinated) 3.8% higher vaccination rate than California

Cumulative deaths per 100k: 75 (103 total deaths) 59.2% less deaths per 100k residents than California

Cumulative cases per 100k: 9,632 (13,268 total cases) 23.9% less cases per 100k residents than California

Population that is fully vaccinated: 69.6% (343,851 fully vaccinated) 11.5% higher vaccination rate than California

Population over 65 that is fully vaccinated: 87.1% (89,171 fully vaccinated) 3.1% higher vaccination rate than California

Cumulative deaths per 100k: 83 (412 total deaths) 54.9% less deaths per 100k residents than California

Cumulative cases per 100k: 8,617 (42,596 total cases) 31.9% less cases per 100k residents than California

Population that is fully vaccinated: 70.5% (192,562 fully vaccinated) 13.0% higher vaccination rate than California

Population over 65 that is fully vaccinated: 93.0% (43,921 fully vaccinated) 10.1% higher vaccination rate than California

Cumulative deaths per 100k: 82 (223 total deaths) 55.4% less deaths per 100k residents than California

Cumulative cases per 100k: 7,971 (21,777 total cases) 37.0% less cases per 100k residents than California

Population that is fully vaccinated: 71.2% (128,939 fully vaccinated) 14.1% higher vaccination rate than California

Population over 65 that is fully vaccinated: 86.5% (20,875 fully vaccinated) 2.4% higher vaccination rate than California

Cumulative deaths per 100k: 423 (766 total deaths) 129.9% more deaths per 100k residents than California

Cumulative cases per 100k: 20,741 (37,585 total cases) 63.9% more cases per 100k residents than California

Population that is fully vaccinated: 72.1% (1,204,312 fully vaccinated) 15.5% higher vaccination rate than California

Population over 65 that is fully vaccinated: 90.4% (215,850 fully vaccinated) 7.0% higher vaccination rate than California

Cumulative deaths per 100k: 89 (1,486 total deaths) 51.6% less deaths per 100k residents than California

Cumulative cases per 100k: 7,408 (123,814 total cases) 41.5% less cases per 100k residents than California

Population that is fully vaccinated: 72.6% (837,826 fully vaccinated) 16.3% higher vaccination rate than California

Population over 65 that is fully vaccinated: 92.9% (174,349 fully vaccinated) 9.9% higher vaccination rate than California

Cumulative deaths per 100k: 90 (1,038 total deaths) 51.1% less deaths per 100k residents than California

Cumulative cases per 100k: 8,897 (102,625 total cases) 29.7% less cases per 100k residents than California

Population that is fully vaccinated: 74.0% (567,516 fully vaccinated) 18.6% higher vaccination rate than California

Population over 65 that is fully vaccinated: 89.7% (113,858 fully vaccinated) 6.2% higher vaccination rate than California

Cumulative deaths per 100k: 82 (626 total deaths) 55.4% less deaths per 100k residents than California

Cumulative cases per 100k: 7,263 (55,676 total cases) 42.6% less cases per 100k residents than California

Population that is fully vaccinated: 75.7% (666,937 fully vaccinated) 21.3% higher vaccination rate than California

Population over 65 that is fully vaccinated: 86.4% (122,430 fully vaccinated) 2.2% higher vaccination rate than California

Cumulative deaths per 100k: 76 (667 total deaths) 58.7% less deaths per 100k residents than California

Cumulative cases per 100k: 6,372 (56,176 total cases) 49.7% less cases per 100k residents than California

Population that is fully vaccinated: 76.5% (1,474,563 fully vaccinated) 22.6% higher vaccination rate than California

Population over 65 that is fully vaccinated: 92.3% (247,667 fully vaccinated) 9.2% higher vaccination rate than California

Cumulative deaths per 100k: 99 (1,916 total deaths) 46.2% less deaths per 100k residents than California

Cumulative cases per 100k: 7,775 (149,882 total cases) 38.6% less cases per 100k residents than California

Population that is fully vaccinated: 79.0% (204,441 fully vaccinated) 26.6% higher vaccination rate than California

Population over 65 that is fully vaccinated: 90.7% (53,907 fully vaccinated) 7.3% higher vaccination rate than California

Cumulative deaths per 100k: 96 (248 total deaths) 47.8% less deaths per 100k residents than California

Cumulative cases per 100k: 7,036 (18,210 total cases) 44.4% less cases per 100k residents than California

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20 counties with the highest COVID-19 vaccination rate in California - KTLA

Why Moderna wont share rights to the COVID-19 vaccine with the government that paid for its development – KRQE News 13

November 21, 2021

(THE CONVERSATION) A quietmonthslong legal fightbetween the U.S. National Institutes of Health and drugmaker Moderna over COVID-19 vaccine patents recently burst into public view. The outcome of the battle has important implications, not only for efforts to contain the pandemic but more broadly for drugs and vaccines that could be critical for future public health crises.

Moderna recentlyoffered to share ownershipof its main patent with the government to resolve the dispute. Whether or not this is enough to satisfy the governments claims, I believe the dispute points to serious problems in the ways U.S. companies bring drugs and vaccines to market.

US was a major funder of the Moderna vaccine

Vaccines haveplayed a crucial rolein the response to the pandemic.

In December 2020, Moderna became the second pharmaceutical company after Pfizer toobtain authorizationfrom the Food and Drug Administration to market a COVID-19 vaccine in the United States. People have since grown so used to talking about the Moderna vaccine that a crucial element in the history of how it was developed risks being overshadowed: Moderna wasnot the sole developerof the vaccine.

Unlike many of the other pharmaceutical companies involved in theCOVID-19 vaccine race, Moderna is a newcomer to drug and vaccine commercialization. Founded in Massachusetts in 2010, the company hadnever brought a product to marketuntil the FDA authorized its COVID-19 vaccine last year.

Throughout the 2010s, Moderna focused on the development ofmRNA technology, attracting overUS$2 billion in fundingfrom pharmaceutical companies and other investors.It went publicin 2018.

Evenbefore the pandemic, research on both coronaviruses and vaccine candidates against emerging pathogens was a priority for agencies operating in the public health space. In 2015, theNational Institute of Allergy and Infectious Diseases, an institute within the NIH,signed a cooperative R&D agreementwith Moderna on basic research, including the development of new vaccines. The agreement resulted in anundisclosed amount of fundingand assistance with research.

In addition, after the COVID-19 outbreak began Moderna alsoreceived almost $1 billioninfundingfrom theBiomedical Advanced Research and Development Authority, which operates within the Department of Health and Human Services. This funding was specifically targeted to the development of a COVID-19 vaccine candidate.

Researchers have calculated that, collectively, the U.S. governmenthas provided $2.5 billiontoward the development and commercialization of Modernas COVID-19 vaccine.

US, Moderna scientists working side by side

In addition to providing financial support, the federal government was instrumental in the development of Modernas vaccine for other reasons. Namely, federal scientists worked alongside Moderna scientists on different components of the vaccine.

These contributions includedworking on dosing mechanisms, and the NIH said federal scientists created thestabilized spike proteinsthat are a key component of the vaccine made by Moderna.

The importance of the role played by federal scientists in their work with Moderna would soon become apparent. A2019 agreementwith a third party explicitly acknowledged this, alluding to mRNA vaccine candidates developed and jointly owned by NIAID and Moderna. And by late 2020, the U.S. government was calling it the NIH-Moderna COVID-19 vaccine.

While the U.S. government has spent money onCOVID-19 vaccinesmade by other companies, its close involvement in the R&D stages of Modernas sets it apart.

How it became a patent dispute

As development of the vaccine progressed, Moderna applied forseveral patents, each one covering different components of the vaccine. U.S. law allows inventors to apply for patents on products or methods that arenew, not obvious and useful. While some early modern vaccines like thepolio vaccinedeveloped by Jonas Salks team werenot coveredby patents, from the late 20th century onwardit became very commonfor one or multiple patents to cover a newly developed vaccine.

In applying for some patents related to its vaccine, Moderna named National Institute of Allergy and Infectious Diseases scientists as co-inventors alongside Moderna scientists. This was the case, for example, in apatent applicationdated May 2020 for a relatively minor component of the vaccine.

However, in July 2021, Moderna made it clear that it would not name government scientists as co-inventors in apatent applicationcovering a much more significant component of the vaccine: the mRNA sequence used to produce the vaccine, known as mRNA-1273.

Modernas position was thatModerna scientists alonehad selected the sequence. Thecompany informedthe Patent and Trademark Office of its position in a 2020 statement.

In November 2021, government officials publicly challenged the companys decision after months offailed negotiationswith the company. Moderna thentook to social mediato defend its position, tweeting:

Just because someone is an inventor on one patent application relating to our COVID-19 vaccine does not mean they are an inventor on every patent application relating to the vaccine.

By contrast, the National Institutes of Healthargued that three NIAID scientists Kizzmekia Corbett, Barney Graham and John Mascola had meaningfully contributed to the invention, thoughtheyve declinedtopublicly specify how. If true, patent law says theyshould be named co-inventors.

But this dispute is not merely about scientific principles or technical aspects of the law. While patents are also regarded as proxies for measuring scientific reputation, their most immediate and powerful effect is to give patent holders asignificant amount of controlover the covered technology in this case, the main component of the vaccine made by Moderna.

From a practical perspective, excluding federal scientists from the application means that Moderna alone gets to decide how to use the vaccine, whether to license it and to whom. If, by contrast, the government co-owns the vaccine,federal patent law allowseach of the joint owners to engage in a variety of actions from making and selling the vaccine to licensing it without the consent of the other owners.

This is especially relevant in cases of product scarcity or potential pricing issues in connection with the commercialization of the vaccine. For instance, the U.S.would have the abilityto allow more manufacturers to produce vaccines using the mRNA-1273 technology. In addition, it could direct vaccine doses wherever it likes, including tolower-income countries that have received few vaccines so far.

Broader implications

The ongoing battle between the government and an emerging star in the pharmaceutical industry is yet another episode in a complicated relationship between actors with complementary yet distinct roles in the production of drugs and vaccines.

On the one hand, the federal governmenthas long played a critical rolein both performing and funding basic research. On the other, it does not have the resources and capacity to bring most types of new drugs and vaccines to market on its own.

The pharmaceutical industry thus plays an important and necessary role in drug innovation, which I believe should be rewarded although not boundlessly.

If the NIH is correct about co-ownership of the vaccine, then Moderna is unduly using a legal tool to achieve a position of market control a reward it does not deserve. This position of sole control becomes even more problematic in light of the significant amounts of public money that funded the development of this vaccine. This offset some of Modernas financial risk, even as thecompany projectsto make $15 billion to $18 billion in revenue from vaccine sales in 2021 alone, with much more expected in 2022.

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However, even if the NIH prevails in the patent dispute, it is important to understand the limitations of such a win. The U.S. would be in a position to license the vaccine, for example, and could do so by requiring that licensees agree to equitable distribution of vaccine doses.

But co-ownership would not enable the government to fix any of theother problemsthat currently affect the manufacturing and distribution of COVID-19 vaccines, such as scaling up production or building infrastructure to deliver vaccine doses.

In my view, the dispute is a reminder of themanyproblemsembedded in how vaccines are made and delivered in the U.S. And it shows that when taxpayers fund basic research of a drug, they deserve more of the control and rewards when that drug succeeds.

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Why Moderna wont share rights to the COVID-19 vaccine with the government that paid for its development - KRQE News 13

6-year-old son of Boston Mayor Michelle Wu receives first dose of COVID-19 vaccine – WCVB Boston

November 21, 2021

Boston Mayor Michelle Wu's 6-year-old son received his first dose of the Pfizer COVID-19 vaccine on Saturday.Wu and her son, Blaise, made a visit to the family vaccination clinic at Prince Hall Grand Lodge. The clinic is being run by the Boston Public Health Commission and the Harvard Street Neighborhood Health Center.Blaise got his shot 18 days after the U.S. Centers for Disease Control and Prevention authorized the use of Pfizer's pediatric COVID-19 vaccine for children ages 5 to 11 on Nov. 2."The vaccine is the most important tool we have to keep schools open and keep everyone safe in our communities," Wu said in a statement. "Now that children ages five and older are eligible for the vaccine, even more families have the chance to do our part to end this pandemic. As we head into the winter months and the holiday season, lets all move quickly to get our kids vaccinated and get our boosters so everyone can enjoy the holidays. According to city officials, 14% of children ages 5 to 11 in Boston have received their first dose of the COVID-19 vaccine since Nov. 2, and nearly 67% of all Boston residents are fully vaccinated.Officials say, however, that Boston continues to see disparities by neighborhood and race, and that they are supporting community-based organizations across the city's neighborhoods to close those gaps.We have noted a recent increase in COVID-19 cases community-wide. Though very rare, COVID-19 in children can result in severe complications, including hospitalization and death. Research has shown that vaccination in kids is more than 90% effective in preventing symptomatic COVID-19 infection, Dr. Bisola Ojikutu, executive director of the BPHC, said in a statement. As a doctor and a mother of a 5-year-old who has received her first dose of vaccine, I strongly encourage parents and guardians to have their children vaccinated. The Boston Public Health Commission is supporting seven family COVID-19 vaccination clinics across the city, including the site at Prince Hall Grand Lodge in Dorchester. The other sites, which offer both pediatric vaccines and adult boosters, include the following:Immigrant Family Services Institute in MattapanGallivan Community Center in MattapanMorningstar Baptist Church in MattapanGreater Roslindale Medical and Dental Center in RoslindaleHyde Park YMCA in Hyde ParkCodman Square Health Center in DorchesterThe BPHC is also working with Boston Public Schools and health care providers to ensure that the vaccine is accessible to all of Boston's children, including at school-based vaccination clinics. Click here for dates and times of school vaccine clinics.Every Boston resident aged 18 and older who received the Pfizer or Moderna vaccine at least six months ago, or the Johnson & Johnson vaccine at least two months ago, is now eligible to receive any booster after CDC Director Dr. Rochelle Walensky endorsed the move on Friday.Visit Boston.gov to view a list of COVID-19 vaccination sites in the city. Residents can also call the Mayor's Health Line at 617-534-5050 to learn more.

Boston Mayor Michelle Wu's 6-year-old son received his first dose of the Pfizer COVID-19 vaccine on Saturday.

Wu and her son, Blaise, made a visit to the family vaccination clinic at Prince Hall Grand Lodge. The clinic is being run by the Boston Public Health Commission and the Harvard Street Neighborhood Health Center.

Blaise got his shot 18 days after the U.S. Centers for Disease Control and Prevention authorized the use of Pfizer's pediatric COVID-19 vaccine for children ages 5 to 11 on Nov. 2.

"The vaccine is the most important tool we have to keep schools open and keep everyone safe in our communities," Wu said in a statement. "Now that children ages five and older are eligible for the vaccine, even more families have the chance to do our part to end this pandemic. As we head into the winter months and the holiday season, lets all move quickly to get our kids vaccinated and get our boosters so everyone can enjoy the holidays.

According to city officials, 14% of children ages 5 to 11 in Boston have received their first dose of the COVID-19 vaccine since Nov. 2, and nearly 67% of all Boston residents are fully vaccinated.

Officials say, however, that Boston continues to see disparities by neighborhood and race, and that they are supporting community-based organizations across the city's neighborhoods to close those gaps.

We have noted a recent increase in COVID-19 cases community-wide. Though very rare, COVID-19 in children can result in severe complications, including hospitalization and death. Research has shown that vaccination in kids is more than 90% effective in preventing symptomatic COVID-19 infection, Dr. Bisola Ojikutu, executive director of the BPHC, said in a statement. As a doctor and a mother of a 5-year-old who has received her first dose of vaccine, I strongly encourage parents and guardians to have their children vaccinated.

The Boston Public Health Commission is supporting seven family COVID-19 vaccination clinics across the city, including the site at Prince Hall Grand Lodge in Dorchester. The other sites, which offer both pediatric vaccines and adult boosters, include the following:

The BPHC is also working with Boston Public Schools and health care providers to ensure that the vaccine is accessible to all of Boston's children, including at school-based vaccination clinics. Click here for dates and times of school vaccine clinics.

Every Boston resident aged 18 and older who received the Pfizer or Moderna vaccine at least six months ago, or the Johnson & Johnson vaccine at least two months ago, is now eligible to receive any booster after CDC Director Dr. Rochelle Walensky endorsed the move on Friday.

Visit Boston.gov to view a list of COVID-19 vaccination sites in the city. Residents can also call the Mayor's Health Line at 617-534-5050 to learn more.

Continued here:

6-year-old son of Boston Mayor Michelle Wu receives first dose of COVID-19 vaccine - WCVB Boston

More than half of Athens County has begun the COVID-19 vaccination process as of Nov. 20 – WOUB

November 21, 2021

By: Aaron PaynePosted on: Saturday, November 20, 2021

ATHENS, Ohio (WOUB) A little more than half of Athens County residents have started the COVID-19 vaccination process as of Saturday, according to the Ohio Department of Health.

The data surrounding vaccinations started in Athens County as of Nov. 20, 2021. [ODH]A total of 50.25% of the county has received at least one dose of the vaccine. Meanwhile, 46.38% has been fully vaccinated and 7,321 additional doses have been administered.

Athens County has now had 8,171 total cases of COVID-19 since the beginning of the pandemic after 17 new cases were reported Saturday.

The Ohio Department of Health confirmed the numbers on Nov. 20, 2021.

According to ODH data, the cases involved seven people 0-19, five people 20-29, three people 60-69, one person 30-39 and one person 80+.

There are 226 known active cases in the county as of Saturday and 7,851 recovered cases, according to ODH.

Anyone experiencing respiratory symptoms is asked to call their primary care physician, urgent care, or emergency department before arriving for care to let them know that they believe they are experiencing symptoms related to COVID-19 virus.

An age breakdown of Athens Co. COVID-19 cases for Nov. 20, 2021. [ODH]Saturday at 2 p.m., the Ohio Department of Health announced 1,639,070 confirmed and probable cases of COVID-19 statewide after 5,590 cases were reported in the last 24 hours. There have been 84,073 hospitalizations since the start of the pandemic.

ODH makes the following recommendations to protect yourself from illness:

Ohios coronavirus call center is open to answer questions from 8 a.m. to 9 p.m. daily. The hotline number is 1-833-4-ASK-ODH or 1-833-427-5634. More information is available atcoronavirus.ohio.gov.

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More than half of Athens County has begun the COVID-19 vaccination process as of Nov. 20 - WOUB

Unvaccinated-Only Lockdowns Come to Europe – The Atlantic

November 21, 2021

For a while, during the worst of the pandemic last year, European governments largely seemed to reach a consensus. Barring a few exceptions (such as Sweden), countries in the region locked down their economies, keeping people at home in a bid to slow the pace of infection. In time, bolstered by plentiful vaccines, the continent has seen a resumption of near-normalcy: Public-health restrictions have loosened, and travel has restarted.

But as temperatures drop, and as rising cases place Europe back in the epicenter of the pandemic, the continent is once again being forced to grapple with tougher measures in a desperate bid to alleviate pressure on hospitals that are coming under strain. This time, however, European countries are no longer in broad agreement on the best path forward.

While several countries have followed Frances lead by implementing vaccine passports as a way to encourage people to get vaccinated, others are poised to follow the alternative recently set out by Austria, which this week instructed millions to stay home except for essential activities, such as going to work, grocery shopping, and exercise. Unlike previous national lockdowns, however, this one applied to only a subset of the country: the unvaccinated. Yesterday, the Austrian government took it one step further, announcing that restrictions would extend to the rest of the population for a maximum of 20 days starting next week and that vaccination would become obligatory as early as February.

The goal of both models is ultimately the sameto get more people vaccinatedbut the differences are key. In France, vaccination is strongly encouraged, though not necessarily required. Under its vaccine-passport system, those who are unvaccinated can still access public spaces if they can provide proof of having recently recovered from a COVID-19 infection, or a negative COVID test. In Austria, the opposite has now become true: Not only are unvaccinated people (excluding those who have recently recovered from COVID and children under the age of 12) poised to be barred from public spaces even after the national lockdown ends, facing fines of up to 1,450 euros ($1,640) if they fail to comply, but they will soon be subject to legal repercussions if they refuse to get a jab.

The question facing governments in Europe and elsewhere is which approachcarrot versus stickwill prove the most effective. By singling out the unvaccinated, Austria may succeed in increasing its vaccination rate, but it also runs the risk of driving vaccine skepticism even further.

In Austria, the unvaccinated still make up a sizable proportion of the population. Nearly a third of the country, or roughly 2 million people, has opted against getting a jabresulting in one of the lowest vaccination rates in Western Europe. Meanwhile, the country continues to break records for daily reported cases just as intensive-care units in some parts of the country near capacity.

To hear Austrian Chancellor Alexander Schallenberg tell it, this weeks drastic intervention wasnt designed to punish those who arent vaccinated. Rather, it was meant to prevent those who have been vaccinated from being held hostage by the unvaccinated minority. To subject everyone to new restrictions (as the government has now been compelled to do, albeit for a time-limited period) would be to risk undermining the incentives that compelled so many people to get vaccinated in the first place. It would also fail to address the fact that the growing strain on the countrys ICUs is largely being driven by unvaccinated patients. Austrias neighborsGermany, the Czech Republic, and Slovakiahave since announced that they will follow suit with tighter restrictions on the unvaccinated.

At some point, reality has to hit home: If the health-care system reaches its limits, then additional steps have to be taken eventually, Eva Schernhammer, the epidemiology-department chair at the Medical University of Vienna, told me. In the minds of some, she said, it just doesnt feel right [for] the government to impose measures on those who have done everything they can just to protect those who didnt.

David Frum: Vaccinated America has had enough

The challenge of addressing the lag in vaccination is what ultimately drove French President Emmanuel Macron to mandate the use of vaccine passports earlier this year. Despite what many naysayers said about the impact that such a strategy would have on more vaccine-hesitant populations (mea culpa, I was one of them), this approach has largely been viewed as a success. Even though France is one of the worlds most vaccine-hesitant countries, it has now vaccinated roughly three-quarters of its population, according to the governments vaccine trackernearly double the number of people who indicated that they would be willing to get a jab at the end of last year. Although the countrys infection rate continues to rise, it remains low relative to that of many of its neighbors.

But what worked for France hasnt necessarily worked for Austria. Despite implementing its own vaccine-passport system this year, the countrys vaccination rate has nonetheless stagnateda trend that has been attributed in part to the high levels of vaccine hesitancy among Europes German-speaking countries, where dispassionate public-health messaging has been supplanted by vocal anti-vaccine sentiment and conspiracy theories. In Austria, this phenomenon has manifested most notably in the rise of the new vaccine-skeptical People Freedom Fundamental Rights Party (known by its German acronym, MFG), which recently garnered enough support to enter one of the countrys largest regional parliaments.

So far, the unvaccinated lockdown in Austria appears to be having its desired effect, with some vaccination centers reportedly seeing an uptick in people seeking a first dose. But it has also spurred thousands of people to protest the new measures, which many have decried as discriminatory. Now that the lockdown is being extended to everyone, and now that vaccinations will soon be made a legal requirement, those protests are only likely to grow. One risk facing the Austrian government is that these new measures could spur even further support for parties such as the MFG and the more established far-right Freedom Party, whose leader said the new restrictions make Austria tantamount to a dictatorship. Another risk is that they could push those who are merely hesitant about getting a COVID vaccine to adopt a more hard-line anti-vax position.

One thing that people really want is some level of choice, and one of the Achilles heels of vaccines has been the feeling that its government-driven and its not about choice, Heidi Larson, the director of the Vaccine Confidence Project at the London School of Hygiene and Tropical Medicine, told me. Larson noted that although vaccine passports offer some element of choice (in that the unvaccinated can opt to provide a negative COVID test instead), unvaccinated-only lockdowns and vaccine mandates could be seen as more punitive.

Read: The pandemics next turn hinges on three unknowns

But perhaps the greatest risk for Austria right now is that these measures alone wont be enough to minimize hospitalizations, which is the primary metric that the government is focused on. That the tightening of restrictions in recent weeks isnt yet reflected in the numbers is a worrying sign, Schernhammer said.

You can impose rules, but if people dont follow, then it gets hard to do anything, she said. We have reached uncharted territory already, because what happens now will be seen in the ICU in two weeks.

Originally posted here:

Unvaccinated-Only Lockdowns Come to Europe - The Atlantic

Australian Open Will Require Players to Be Fully Vaccinated – The New York Times

November 21, 2021

Novak Djokovic in Melbourne, Australia, in February. He is the reigning Australian Open mens singles champion and has declined to divulge his vaccination status.Credit...Asanka Brendon Ratnayake/Reuters

The Australian Open in January will become the first Grand Slam tennis tournament to require that players be fully vaccinated against the coronavirus, a decision that casts doubt on the participation of Novak Djokovic of Serbia, the No. 1-ranked mens player, who has declined to divulge his vaccination status.

Craig Tiley, the Australian Open tournament director, confirmed the tournaments policy in a television interview in Melbourne on Saturday.

The announcement ended months of speculation and mixed messages from Australian government officials. Federal authorities had indicated that unvaccinated players might be able to enter Australia and compete in the tournament in Melbourne after a 14-day quarantine period. But Daniel Andrews, the premier of the state of Victoria, has been adamant that players will need to be fully vaccinated, just as Australian Open spectators and on-site employees will be required to be vaccinated.

Melbourne, Victorias capital, has experienced some of the strictest coronavirus measures in the world, with six separate stay-at-home orders over an 18-month period.

It is the one direction that you can take that you can ensure everyones safety, and all the playing group understands it, Mr. Tiley said of requiring players to be vaccinated. Our patrons will need to be vaccinated. All the staff working the Australian Open will need to be vaccinated, but when were in a state where theres more than 90 percent of the population fully vaccinated theyve done a magnificent job with that its the right thing to do.

Source: Center for Systems Science and Engineering (CSSE) at Johns Hopkins University. The daily average is calculated with data that was reported in the last seven days.

Steve Simon, the chief executive of the Womens Tennis Association, said in an interview this past week that over 70 percent of the W.T.A.s top 300 singles players and top 100 doubles players had been vaccinated and that all of the singles and doubles players who competed in the recent W.T.A. finals in Mexico had been vaccinated.

Andrea Gaudenzi, the chairman of the mens tour, said in an interview on Friday that the vaccination rate for the top 100 mens singles players was above 80 percent.

We are moving toward 90 percent, 95 percent of fully vaccinated, he said. A lot will do it in the off-season with one shot.

But it seems all but certain that some qualified players will not make the journey to Australia because of the policy.

All four Grand Slam tournaments, including the U.S. Open, allowed unvaccinated players to participate this year, as have regular tour events.

Djokovic, a nine-time Australian Open singles champion, has yet to confirm whether he will defend his title next year. He and his wife, Jelena, contracted the coronavirus in June 2020 during an exhibition tour that he had helped to organize in Serbia and Croatia.

He has expressed concern about vaccines and has said repeatedly that he would wait for the Australian Opens policy to be made clear before making a decision on participating.

The Centers for Disease Control and Prevention on Friday endorsed booster shots of the Pfizer-BioNTech and Moderna coronavirus vaccines for all adults, a move that brings tens of millions fully vaccinated people a step closer to a third shot.

Boosters are recommended six months after the second shot of the Pfizer-BioNTech or Moderna vaccines. With this final step, boosters should be available this weekend, allowing many Americans to get a shot before the Thanksgiving holiday.

The new recommendations say that everyone 50 and older most of whom have other risk factors as well as those 18 and older living in long-term care facilities should get a booster. Other Americans who are 18 and older may opt for one if they wish, based on individual risk and benefit.

Several advisers said at the meeting that they hoped the simpler age-based guidelines would ease some of the confusion around who is eligible for the extra shots.

An advisory committee to the C.D.C. unanimously voted in favor of the booster shots. Dr. Rochelle Walensky, the agencys director, later formally accepted the recommendation. The recommendations align with President Bidens promise in August that all adults would be eligible for extra doses.

Desperate to dampen even a dim echo of last winters horrors, the administration is betting that booster shots will shore up what some have characterized as waning immunity among the fully vaccinated.

The Food and Drug Administration authorized boosters of the Pfizer-BioNTech and Moderna vaccines for all adults on Friday, but the C.D.C. generally makes the recommendations followed by the medical profession.

In recent days, several states have broadened booster access to all adults on their own.

Addressing the panelists, Dr.SamPosner, the acting director of the National Center for Immunization and Respiratory Diseases, acknowledged that previous eligibility categories were complicated to implement and said he hoped that simplifying them will reduce confusion.

After a brief respite, coronavirus infections are inching up again, particularly in parts of the country where cooler weather is hustling people indoors. Research suggests that the shots may help forestall at least some infections, particularly in older adults and those with certain health conditions.

The C.D.C.s decision lands just as Americans are preparing to spend the holidays with family and friends. Given the tens of millions of Americans who have yet to receive a single dose of vaccine, holiday travel and get-togethers could send cases skyrocketing, as they did last year.

Several European countries are also offering boosters to all adults in a bid to contain fresh waves of infections. France has gone so far as to mandate booster shots for people over age 65 who wish to get a health pass permitting access to public venues.

Noah Weiland and Dan Levin contributed reporting.

Pregnant women who had Covid-19 when they delivered their babies were almost twice as likely to have a stillbirth as healthy women who did not have Covid, according to a Centers for Disease Control study released on Friday that examined more than 1.2 million deliveries in the United States from March 2020 to September 2021.

While stillbirths were rare overall, representing less than 1 percent of all births, 1.26 percent of the 21,653 women with Covid experienced a stillbirth, compared with 0.64 percent of women without Covid. Even after adjustments were made to control for differences between the groups, women with Covid were 1.9 times as likely as healthy women to have a stillbirth.

The risk of stillbirth has been even higher for women with Covid since the Delta variant has been dominant: While the risk of stillbirth for women with Covid was 1.5 times as high as that of healthy women before July, when Delta became dominant, it was four times as high from July to September. As many as 2.7 percent of deliveries to women with Covid were stillbirths during the period studied while Delta was dominant.

There had been reports suggesting an increased risk, but stillbirths are hard to study, because luckily they are uncommon, said Dr. Denise Jamieson, the chief of gynecology and obstetrics at Emory Healthcare. This is some of the strongest evidence of the increased risk, and probably the strongest data pointing to the risks specifically tied to Delta.

The C.D.C. strongly encourages pregnant and breastfeeding women and women planning or trying to become pregnant to be vaccinated against Covid, but resistance has been strong, even though pregnancy is on the C.D.C.s list of health conditions that increase the risk of severe disease.

Studies have shown that pregnant patients who are symptomatic are more than twice as likely as other symptomatic patients to require admission to intensive care or interventions like mechanical ventilation, and they may be more likely to die. They are also more likely to experience a preterm birth.

Another C.D.C. study issued on Wednesday described the cases of 15 pregnant women in Mississippi who died of Covid during their pregnancy or shortly afterward, including six who died before the Delta variant became dominant and nine who died from July to October, while Delta was dominant.

Of the women who died, nine were Black, three were white and three were Hispanic. The median age was 30. Fourteen of the women had underlying medical conditions, and none were vaccinated. Five of the deaths occurred before vaccinations were available.

Austria on Friday became the first Western democracy to announce that it would mandate Covid vaccinations for its entire adult population as it prepared for a nationwide lockdown starting Monday.

The extraordinary measure by Austria, which only days ago separated itself from the rest of Europe by introducing a lockdown for the unvaccinated, who are driving a surge of infections, made for another alarming statement about the severity of the fourth wave of the virus in Europe, now the epicenter of the pandemic.

But it also showed that increasingly desperate governments are losing their patience with vaccine skeptics and shifting from voluntary to obligatory measures to promote vaccinations and beat back a virus that shows no sign of waning, rattling global markets at the prospect that still tentative economic recoveries will be undone.

Some European countries, including Germany, which once seemed a model of how to manage the virus, are now facing their worst levels of infections in the nearly two years since the pandemic began. The surge, health authorities say, is being driven by stubborn resistance to getting vaccinated in deep pockets of the population, cold weather driving people indoors, loosened restrictions and possibly waning immunity among those previously vaccinated.

Source: Center for Systems Science and Engineering (CSSE) at Johns Hopkins University. The daily average is calculated with data that was reported in the last seven days.

For a long time maybe too long I and others assumed that it must be possible to convince people in Austria to voluntarily get vaccinated, Chancellor Alexander Schallenberg of Austria said on Friday. We therefore have reached a very difficult decision to introduce a national vaccine mandate.

With its latest move, Austria significantly moved ahead of other European countries that have inched up to, but not crossed, a threshold that once seemed unthinkable. The announcement drew an immediate threat of violent protest this weekend by leaders of anti-vaccine movements and the far-right Freedom Party, which compared the governments latest mandates with those of a dictatorship.

Many European countries have already instituted mandates in all but name only requiring strict health passes as proof of vaccination, recovery from infection or a negative test to partake in most social functions, travel or to go to work. Many already require children to be vaccinated against measles and other illnesses to attend school.

The notion of requiring vaccination in adults against Covid was a line that Europe had seemed unwilling to cross, however, with leaders often contrasting their respect for civil liberties with authoritarian-styled countries.

But just as lockdowns have become a fact of life, vaccine mandates are increasingly becoming plausible. German lawmakers in Parliament voted on Thursday to force unvaccinated people going to work or using public transit to provide daily test results. The countrys vaccination rate among adults is about 79 percent, one of the lowest in Western Europe.

On Friday, Jens Spahn, the acting health minister in Germany, was asked whether a general lockdown was possible for the country. We are in a position where nothing should be ruled out, he said.

The specter of a lockdown in Germany, Europes largest economy, sent jitters through European markets hungering for economic recovery and sales during the Christmas shopping season.

Austrias new vaccine mandate will take effect in February, in the hopes that as many people as possible will be motivated to sign up for their initial inoculations, but also booster shots, Austrias health minister, Wolfgang Mckstein, said.

It also gave leaders time to formalize legal guidelines for the mandate, he said, adding that there would be exceptions for people who are not able to be vaccinated.

An earlier version of this briefing item incorrectly described the nature of Austrias planned nationwide lockdown. It will be among the first in Europe since the spring, not the first.

Gov. Bill Lee said on Friday that he would not renew Tennessees state of emergency, ending measures that he first put in place in response to the coronavirus outbreak in March 2020.

The governor announced the decision in a tweet:

Mr. Lee added that he would consider temporarily reinstating the measures should the state face any future surges, but that his administration was evaluating opportunities for permanent deregulation.

Recently, cases in Tennessee reached a peak in early September before dropping steeply, but infections have been rising again in recent days.

Source: State and local health agencies. Daily cases are the number of new cases reported each day. The seven-day average is the average of a day and the previous six days of data.

Mr. Lee, a Republican, has been active in rolling back pandemic restrictions. Last week, he signed a bill into law that prohibited government entities, schools and private businesses in Tennessee from requiring Covid vaccinations or proof of vaccination and limited their ability to impose mask mandates. The law also prohibited health care providers from vaccinating minors without the written consent of a parent or legal guardian.

On Wednesday, the governor made a pitch to law enforcement personnel who were leaving states with restrictive mandates to join the Tennessee Highway Patrol, going so far as offering to help pay their moving expenses.

With the holiday travel season nearing, Canadian officials announced several measures on Friday meant to standardize international travel and make it easier for Canadians taking short trips to re-enter the country.

Travelers who are fully vaccinated with the shots from Sinopharm, Sinovac and Covaxin will be allowed to enter Canada starting Nov. 30, opening the door wider to people from countries like India, Brazil and China, where those vaccines are more frequently administered.

Currently, Canada only accepts travelers who have received the Pfizer-BioNTech, Moderna, Oxford-AstraZeneca or Johnson & Johnson vaccines, the four shots approved in the country. The expanded list will align with the vaccines cleared for use by the World Health Organization.

Dr. Theresa Tam, Canadas chief public health officer, said that the case rates associated with each of the vaccines were about the same.

All that is very reassuring, Dr. Tam said. She added that although Sinopharm, Sinovac and Covaxin are not authorized in Canada, because theyve gone through the W.H.O. process in terms of evaluation of safety, of efficacy and of quality, weve taken that into account as we increase the list of vaccines for Canadian border measures.

Source: Center for Systems Science and Engineering (CSSE) at Johns Hopkins University. The daily average is calculated with data that was reported in the last seven days.

Additionally, people leaving Canada by land or by air for less than 72 hours will no longer be required to provide proof of a negative Covid-19 test to re-enter the country. The price and processing time of P.C.R. tests which can cost more than $100 and take longer than a day for results were widely seen as deterrents to travel.

This change applies only to Canadians, permanent residents and Indigenous people registered under the Indian Act. It also takes effect Nov. 30.

The government will take a firm stance against unvaccinated travelers entering and leaving the country beginning on that date as well, with very few exemptions, said Omar Alghabra, Canadas transport minister. He added that only fully vaccinated travelers would be able to fly from a Canadian airport or board a Via Rail or Rocky Mountaineer train.

Starting Jan. 15, Canada will also phase out most previously granted travel exemptions for those who are unvaccinated. This will affect professional and amateur athletes, foreign students, truck drivers and other essential workers who cross the border, and adults over 18 traveling to reunite with a family member.

Other categories of unvaccinated or partly vaccinated travelers such as refugees, marine crews and agricultural workers will be able to enter only with limited approval.

BRUSSELS The European Unions drug regulator on Friday recommended the use of a pill, developed by Merck, that was found in a clinical trial to halve the rate of hospitalizations and deaths in high-risk Covid patients who took it soon after infection.

The drug, molnupiravir, has yet to be authorized by E.U. countries, but in recommending its administration, the European Medicines Agency paved the way for its use within the next few months.

Several E.U. countries, including France and Italy, have already placed orders for supplies of the drug.

Britain became the first country this month to authorize the use of the pill. Its regulator authorized it for vaccinated and unvaccinated people who have Covid and are at high risk of becoming severely ill. The treatment could be authorized in the United States as soon as early December.

The European Medicines Agency said the drug could be taken by adults who do not require supplemental oxygen and who are at increased risk of developing severe coronavirus cases. The pill should be administered as soon as possible after diagnosis of Covid-19 and within five days of the start of symptoms, the agency said in a news release.

The agency also said on Friday that it had begun reviewing a similar drug developed by Pfizer, called Paxlovid.

Scientists and government leaders have called the drugs game changers in efforts to end the pandemic if their efficacy in clinical trials holds up in the real world. Unlike monoclonal antibodies, which are typically administered by health care professionals at a hospital or clinic, the pills would be dispensed at pharmacies and taken at home, providing a cheaper and easier way to treat coronavirus infections, including in poorer countries.

Merck has agreed to let other manufacturers make and sell its pill in 105 developing nations, including many where vaccination rates are critically low. It has also licensed eight large Indian drug makers to produce generic and cheaper versions of Mercks pill.

In the United States, Pfizer applied to the Food and Drug Administration this past week to authorize Paxlovid, and the Biden administration plans to buy a stockpile of the pill that could be administered to as many as 10 million people.

Canada approved the use of Pfizer-BioNTechs coronavirus vaccine for children ages 5 to 11 on Friday, adding more than 2.8 million young people to those eligible for a shot.

Some provinces, including Ontario and Saskatchewan, have already announced plans to start scheduling appointments for young children as soon as the doses arrive. Canadas first order enough for all eligible children to receive one dose is expected to begin arriving on Sunday, Filomena Tassi, Canadas minister of public services and procurement, said at a news conference. She added that the government was working with Pfizer on a second order.

Overall, this is very good news for adults and children alike, Dr. Supriya Sharma, chief medical adviser at Health Canada, the agency responsible for drug authorization in the country, said at another news conference. It provides another tool to protect Canadians and, to the relief of many parents, will help bring back a degree of normality to childrens lives, allowing them to more safely do the things that they have missed during the last 20 months.

Pfizers is the first coronavirus vaccine to be approved in Canada for children ages 5 to 11. Health Canada based its approval on a clinical trial comprising 4,600 children, Dr. Sharma said, with 3,100 children receiving two doses of the vaccine spaced three weeks apart and 1,500 receiving a placebo.

There were four adverse reactions unconnected to the vaccinations, and none of the children experienced heart inflammation or severe allergic reactions.

Source: Center for Systems Science and Engineering (CSSE) at Johns Hopkins University. The daily average is calculated with data that was reported in the last seven days.

The pediatric doses each one-third of the adult dose will be stored in vials with an orange cap, and the cartons labels will have orange borders, to differentiate them from the adult vials, Christina Antoniou, a spokeswoman for Pfizer Canada, said in an email.

The reduced dose for children results in antibody levels comparable to those from the larger dose in adults, said Dr. Jeffrey Pernica, an infectious diseases specialist at McMaster Childrens Hospital in Hamilton, Ontario. For parents wondering if they should wait until their child turns 12 to get the larger dose, Dr. Pernica noted, the immune response produced by the pediatric vaccine is just as strong.

I dont think waiting would have any significant benefit, he said.

Nearly 75 percent of all Canadians, or more than 28.5 million people, are fully vaccinated.

More than 16,800 coronavirus cases have been reported in Canada in the past seven days, according to national public health data, with the highest per capita rates in Yukon and the Northwest Territories. First Nations reserves are also experiencing high per capita infection rates.

While the number of severe cases has declined nationwide, hospitals in some areas are inching closer to capacity limits, said Dr. Theresa Tam, Canadas chief public health officer. She added that newly reported cases were highest among children.

As Austria prepares to go into a national lockdown next week, the health minister in neighboring Germany suggested on Friday that a similar measure remained an option for his far larger country as coronavirus cases there continue to reach record levels.

We are in a position where nothing should be ruled out, the minister, Jens Spahn, told a news conference in response to a reporters question about a lockdown for both vaccinated and unvaccinated people.

His remarks came one day after lawmakers in Parliament voted to force unvaccinated people going to work or using public transit to provide daily test results. The countrys vaccination rate among adults is about 79 percent.

Source: Center for Systems Science and Engineering (CSSE) at Johns Hopkins University. The daily average is calculated with data that was reported in the last seven days.

Chancellor Angela Merkel and state governors also agreed on Thursday night to require proof of vaccination or recovery from coronavirus infection for people entering restaurants, bars and hair salons or attending events in states where hospital beds are becoming scarce.

But some German states are going it alone.

On Friday, the governor of Bavaria, which has some of the countrys worst hot spots, announced measures including the cancellation of all Christmas markets and the closing of bars, clubs and nightclubs until at least Dec. 15. The celebrated Christmas market in the states capital, Munich, was canceled earlier this week.

Theaters, cinemas, operas and spectator sports will be allowed to remain open at 25 percent capacity for people who are vaccinated or who have recovered from the virus and show a negative test result. Restaurants will close at 10 p.m.

Districts with high infection rates will close down completely, leaving only essential shops, day cares and schools open.

We are facing a corona drama, the states governor, Markus Sder, said. The numbers are exploding in the shortest time span and the beds are full, he added, referring to overwhelmed hospitals. Some patients there are being moved to less crowded hospitals in northern Germany.

The governor of Saxony also announced new restrictions on Friday. Starting on Monday, a ban will be introduced on some events and larger gatherings regardless of the inoculation status of those attending.

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Australian Open Will Require Players to Be Fully Vaccinated - The New York Times

Here are the facts about fetal cell lines and COVID-19 vaccines – National Geographic

November 21, 2021

In the wake of federal vaccine mandates in the U.S., debate has erupted over the waves of fire fighters,police staff, and other workers who have applied for religious exemptions to getting their COVID-19 shots. The number of applications is likely to spike as the January 4 vaccination deadline nears for large private businesses and some healthcare facilities. And one common reason people give for religious exemptions is the link between vaccines and human fetal cells.

Its true that such cells have been used either in the testing or development and production of COVID-19 vaccines. The cells are grown in a laboratory and were derived from a few elective abortions performed more than three decades ago. These same cell lines are also used to test and advance our understanding of several routine drugs, including Tylenol, ibuprofen, and aspirin, and they continue to be used for treatment research in diseases such as Alzheimers and hypertension.

So many people dont realize how important fetal cell lines are to develop life-saving medicines and vaccines that they rely on every day, says Amesh Adalja, an infectious disease expert at Johns Hopkins Center for Health Security. Their use in developing COVID-19 vaccines isnt anything different or special.

For some religious leaders, the science is informing their recommendations. In a December 2020 statement, the U.S. Conference of Catholic Bishops referred to these cell lines as morally compromised for their connection, albeit remote, with abortions. But they reiterated the message from the Vatican justifying the use of vaccines, lacking alternatives, as an act of charity and moral responsibility in situations of serious health danger, such as the COVID-19 pandemic.

Although its unclear how many religious exemptions for COVID-19 shots have been granted so far, those applying are required to prove religious sincerity and in some cases attest that they will also avoid the routine drugs developed using fetal cells.

But doctors worry that some peoples objections may stem in part from misunderstandings of the science. Richard Zimmerman, a family medicine specialist at the University of Pittsburgh School of Medicine and a part-time physician at Pittsburghs East Liberty Family Health Care Center, says that some of his patients have voiced scepticism because they believe the COVID-19 vaccines contain cells from aborted fetuses. This is incorrect.

Here is the history of how fetal cells are used in drug development, where the cells come from, and why its been so hard to find alternatives.

Unlike bacteria, viruses need a host to survive; they can only grow and reproduce inside the host cells they infect. Vaccines typically deliver small doses of weakened or inactivated versions of the virus, or key parts of it, to give the host body a preview of the pathogen without causing illness. This enables the immune system to remember a specific virus and how to destroy it if the body ever encounters the germ in the future.

To mass produce vaccines, manufacturers need a way to make enormous quantities of the viral components.

Scientists use fertilized chicken eggs, for instance, as hosts to multiply influenza viruses and produce the annual flu vaccines. But vaccines manufacturers prefer to grow the virus in mammal cells, mainly because they help prevent the virus from mutating and help scale production.

In the early days, scientists used animal cells. But they later realized that these cells can harbor other undesirable animal viruses, which would then contaminate the vaccine. For instance, an early version of the polio vaccine administered extensively between 1955 and 1963 was produced using monkey cells. But scientists later found out the cells were contaminated with a monkey virus called SV40.

The other issue was that some human viruses didnt grow as well in non-human animal cells. So scientists turned to human fetal cells to produce vaccine viruses.

They were known to rarely contain contaminating viruses, says cell biologist Leonard Hayflick at the University of California, San Francisco. He created the oldest fetal cell strain, known as WI-38, from an elective abortion in Sweden in the early 1960s. Hayflick knew that human fetal cells, unlike adult human cells, were less likely to contain unwanted viruses.

Over the years, though, scientists have identified other animal cells that could be safely used to develop vaccines against certain viruses. African green monkey kidney cells, for instance, have been used to develop several vaccines, including certain ones for polio and smallpox.

But especially with new human viruses, there is preference for using a human cell line, says Alessondra Speidel, a biomaterials scientist at Swedens Karolinska Institute, possibly because theyre likely to infect and grow better in human than animal cells.

To create fetal cell strains, scientists must isolate millions of cells from tiny pieces of tissue collected from a dead embryo. Each cell can divide into two nearly 50 times. And these cells can be frozenor in some cases, immortalizedso that today the cells being used come from tissue collected decades ago.

Hayflick, for instance, has frozen ten million human fetal lung cellsderived from one aborted fetusin each of 700 glass vials after the original cell population had doubled seven times. Given their potential to continue doubling at least another 30 times, each vial can yield tens of thousands of kilos of cells, he says. Thats enough cells to supply the world's vaccine manufacturers with WI-38 cells for several years. These lung cells are currently used to produce vaccines for varicella, rubella, hepatitis A, and rabies. Other scientists have transformed fetal kidney and retinal cells so that they become immortal, dividing forever. The PER.C6 cell line, for instance, is derived from immortalized retinal cells from an 18-week-old fetus aborted in 1985.

Johnson & Johnson uses PER.C6 to produce its COVID-19 vaccine. The company used these cells to grow adenovirusesmodified so that they wouldnt replicate or cause diseasethat were then purified and used to deliver the genetic code for SARS-CoV-2s signature spike protein. The J&J vaccine does not contain any of the fetal cells that once housed the adenovirus because they were extracted and filtered out.

Pfizer and Moderna used another immortal cell line, HEK-293, derived from the kidney of a fetus aborted in the 1970s. The cells were used during development to confirm that the genetic instructions for making the SARS-CoV-2 spike protein worked in human cells. This was like a proof-of-concept test, Speidel says, and the fetal cells were not used to produce either of these mRNA vaccines.

The issue is whether one believes that it is ethically acceptable to develop and use life-saving medicines, vaccines, and treatments that are dependent on a cell line that was created using aborted human fetal cells a half century ago, says Frank Graham, a molecular virology and medicine expert and emeritus professor at Canadas McMaster University, who created the HEK-293 cell line.

Even if future vaccines can somehow avoid the use of these fetal cell lines, its hard to ignore their foundational role. The same applies to the widespread use of these cells in studying several common diseases like diabetes and hypertension and advancing their treatments.

And beyond the science, the message that has resonated most with several of Zimmermans vaccine-hesitant patients is one of altruism. Nobody wants to be the one who triggers an infectious disease on their loved one, he says.

Continued here:

Here are the facts about fetal cell lines and COVID-19 vaccines - National Geographic

Few Alabama children 5 to 11 have received COVID-19 vaccine – alreporter.com

November 18, 2021

After being eligible for two weeks, approximately 1.2 percent of children aged 5 to 11 in Alabama have received Pfizers lower dose COVID-19 vaccine, according to data from the Alabama Department of Public Health.

The lower percentage of younger children receiving the vaccine mirrors Alabamas lower overall vaccination rate across all ages. The state has the fourth-lowest percentage of fully vaccinated residents in the nation at 45 percent, according to the Centers for Disease Control and Prevention.

In Georgia, by comparison, 4.4 percent of children aged 5 to 9 are vaccinated (the states tracker categorizes children by age differently than Alabama) while 29.3 percent of kids between 1o and 14 are vaccinated, according to the Georgia Department of Public Health.

The only vaccine approved for younger children is the lower dose of the Pfizer vaccine, which requires two shots to become fully vaccinated.

Alabama has vaccinated more younger children than neighboring Mississippi, however, where just .2 percent of children aged 5 to 17 are vaccinated against COVID, and Tennessee, where .7 percent of kids 5 to 11 received vaccination.

The percentage of residents vaccinated in Alabama rises in older age categories, however. Nearly half of Alabamians aged 25 to 49 are vaccinated. Just more than 81 percent of those between 65 and 74 are vaccinated while 86.5 percent of Alabamians 75 and older are vaccinated, according to ADPHs data.

The White House on Wednesday said approximately 10 percent of the nations 5-to-11-year-olds have received a dose of the Pfizer vaccine, totaling more than 2.6 million of those younger children.

While children tend to have better outcomes after contracting COVID, severe illness, long-term health impacts and death are still possible. COVID-19 is the eighth leading cause of death for children, Dr. David Kimberlin, co-director of UAB and Childrens of Alabamas Division of Pediatric Infectious Diseases, said recently.

The American Academy of Pediatrics strongly endorses vaccine in five to 11-year-olds, as well as 12 through 17-year-olds. The Infectious Disease Society of America strongly endorses vaccination of pediatric and adolescent patients. The Pediatric Infectious Diseases Society strongly endorses vaccination of pediatric and adolescent patients. This is something across the board thats recommended, Kimberlin said.

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Few Alabama children 5 to 11 have received COVID-19 vaccine - alreporter.com

Baton Rouge COVID-19 vaccination event on Nov. 21 to feature fun for the whole family | La Dept. of Health – Louisiana Department of Health -…

November 18, 2021

The Louisiana Department of Health is partnering with The Links, Incorporateds La Capitale and Baton Rouge chapters as well as other community partners to host a free, family-friendly COVID-19 vaccination event this Sunday, November 21 from 12 p.m. to 4 p.m. at Quarters-Endless Entertainment, 4530 S. Sherwood Forest Blvd. in Baton Rouge.

Similar to what was seen in adult vaccine trials, the vaccine is nearly 91% effective in preventing COVID-19 amongchildren ages 5-11 years. Community-based vaccination events make vaccines more widely accessible and remain an important component of fighting COVID-19 in Louisiana.

Currently, the CDC reports that more than 48% of Louisianans are fully vaccinated against COVID and nearly 53%, about 2.5 million people, have taken at least one dose of the COVID-19 vaccine. In addition, more than 118,000 children in Louisiana have been vaccinated against COVID-19.

Frequently asked questions

Where and how do I get my child vaccinated?

What is the risk of COVID-19 to children?

Why should you consider getting your child vaccinated?

Vaccination, along with other preventative measures, can protect children from COVID-19 using the safe and effective vaccines already recommended for use in adolescents and adults in the United States. The most common side effect was a sore arm.

COVID-19 vaccines have undergone and will continue to undergo the most intensive safety monitoring in U.S. history.Vaccinatingchildrenwill help protect them from getting COVID-19 and therefore reducing their risk of severedisease, hospitalizations, or developing long-term COVID-19 complications.

Getting your children vaccinated can help protect them against COVID-19, as well as reduce disruptions to in-person learning and activities by helping curb community transmission.

What if you have more questions?

Families can call the COVID-19 Vaccine Hotline at 1-855-453-0774 to find a provider in their area and to speak to medical professionals with clinical experience who can help answer their questions.

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Baton Rouge COVID-19 vaccination event on Nov. 21 to feature fun for the whole family | La Dept. of Health - Louisiana Department of Health -...

Ciara to promote Covid-19 vaccination for kids as the White House looks to level up child vaccine rates – CNN

November 18, 2021

The first lady and Ciara will hold a conversation aimed at encouraging children ages 5 to 11 years old to receive a Covid-19 vaccine, part of Biden's ongoing work toward promoting child vaccinations. The conversation, a White House official told CNN, will be shared across Ciara and the White House's social media platforms. Ciara, the first official noted, has an audience of 58 million followers on social media.

The Grammy-winning artist, who is married to Seattle Seahawks quarterback Russell Wilson, was spotted with her three children -- son Win, 1, daughter Sienna, 4, and son Future, 7 -- posing for a photo outside the West Wing.

Later, the group was seen standing on a balcony with the first lady to watch President Joe Biden's White House South Lawn helicopter departure for a trip to Detroit. The President jogged over to greet them before boarding Marine One.

After the meeting, Ciara said she was hoping to educate more people through her visit.

"I think, you know, being educated in this process is really important, because I think that will make a difference for parents and them feeling more comfortable to take a leap of faith basically," Ciara told reporters, adding that Future was vaccinated for Covid-19 just two days ago.

"He walked in, excited and a little nervous, but he was excited, because a lot of his classmates have gotten vaccinated," Ciara said. "So, you know, it was really cool to be on that journey with him, being a mom and you know, seeing it through his eyes, I think, was amazing as well. And I think the ultimate goal was to end this thing, you know, and for us all to feel more safe and how to add a layer protection."

US child vaccine rates have accelerated since the US Centers for Disease Control and Prevention Director Dr. Rochelle Walensky endorsed a recommendation to vaccinate children ages 5-11 against Covid-19 with Pfizer's two-dose course earlier this month.

And there has been progress: the White House estimates by the end of Wednesday, about 10% of children ages 5 to 11, or 2.6 million children, will have received their first Covid-19 vaccine shot, according to White House Covid-19 response coordinator Jeff Zients.

The first lady is in the midst of a nationwide child vaccine effort, making multiple trips and appearances, including a visit to a Children's National medical clinic later Wednesday, to encourage parents and guardians to get their children vaccinated.

CNN's Donald Judd contributed to this report.

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Ciara to promote Covid-19 vaccination for kids as the White House looks to level up child vaccine rates - CNN

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