Category: Covid-19 Vaccine

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Cory Franklin and Robert Weinstein: There is much we still don’t know about giving 5- to 11-year-olds a COVID-19 vaccine – Chicago Tribune

March 29, 2022

This is a nuanced issue, and context matters. Children are certainly at risk from COVID-19 at the beginning of the pandemic in 2020, children accounted for fewer than 3% of cases; today, they account for about 25%. More than 6 million U.S. children have contracted COVID-19, including 2 million ages 5 to 11. Any COVID-19 infection, no matter how trivial, creates the possibility of disruption of home and school activity.

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Cory Franklin and Robert Weinstein: There is much we still don't know about giving 5- to 11-year-olds a COVID-19 vaccine - Chicago Tribune

European Union funding boosts COVID-19 vaccination in Africa – WHO | Regional Office for Africa

March 29, 2022

Brazzaville/Copenhagen The European Commissions Directorate-General for European Civil Protection and Humanitarian Aid Operations (ECHO) is supporting the work of the World Health Organization (WHO) to boost COVID-19 vaccination campaigns and increase coverage in 15 African countries.

With a total of 16 million from ECHO, WHO is supporting operational and technical aspects of the vaccine rollout over 18 months in the following countries: Burundi; Cameroon; Central African Republic; Chad; Democratic Republic of the Congo; Guinea; Liberia; Madagascar; Mali; Mozambique; Niger; Nigeria; Somalia; South Sudan Republic, and Sudan.The grant is also helping to reinforce the capacity of health workers to plan, coordinate and deploy the vaccines as well as monitor and document the results of the rollout and adequately investigate and report any adverse events following immunization.

The funding is part of the European Unions (EU) humanitarian initiative for COVID-19 vaccination in Africa which aims to ensure increased access including for the most vulnerable as well as those living in hard-to-reach, remote and conflict-affected areas. It is also one of the many contributions from the EU and its Member States to the COVID-19 response. The EU also supports the COVAX Facility, the vaccines part of the Access to COVID-19 Tools-Accelerator created to develop and deliver tools to fight the pandemic.

Ever since the COVID-19 pandemic broke out, the EU, its Member States and European financial institutions have come together as Team Europe, contributing to the fight against the pandemic around the world, supporting in particular the African continent, said Paraskevi Michou, Director General for Humanitarian Aid and Civil Protection in the European Commission. In addition to being a leading donor to the COVAX Facility, the EU supports local manufacturing of medicines and vaccines, the strengthening of research, analysis and sequencing capacities, as well as the improvement of health systems at regional and national levels in Africa. The EU has also provided a total of 100 million in humanitarian assistance to specifically support the rollout of vaccination campaigns in Africa, to help ensure equitable access to vaccines for vulnerable people, including in conflict-affected or hard-to-access areas. Our strong cooperation with the World Health Organization is instrumental in implementing this programme successfully.

Efforts are ongoing to scale up COVID-19 vaccine coverage in Africa, where only 15% of the population is fully vaccinated so far. Around 404 million of the more than 716 million doses the continent has received to date have been administered.

In a fresh drive to support countries scale up vaccination, WHO and partner organizations have deployed more than 60 experts on the ground to form part of country expert teams. These teams are working to strengthen coordination, logistical and financial planning, including microplanning, surveillance of adverse events following immunization as well as vaccine uptake and stock data management. WHO partners are also working with people in the communities to strengthen trust and confidence in vaccination.

With African countries striving to expand the COVID-19 vaccination coverage, the support by the European Union injects a crucial momentum into the drive to scale up coverage on continent. Vaccination is the best protection against the adverse impact of the virus and will also prevent new variants from emerging and threatening not only Africa but the world., said Dr Matshidiso Moeti, WHO Regional Director for Africa.

The vaccination campaigns prioritize vulnerable and high-risk populations such as health workers, older people, those with co-morbidities, in particularly living in fragile, conflict-affected and humanitarian contexts, including in refugee camps.

Solidarity is key to ending this pandemic and to building back better. These are not just words. These principles have been already exemplified by the generous support with vaccines and funding provided by the European Union to the global pandemic response. Together in Europe, in Africa and beyond, WHO and the EU are working with local partners to ensure COVID-19 vaccination reaches the arms of everyone and that lessons learned contribute to resilient health systems, said Dr Hans Henri P. Kluge, WHO Regional Director for Europe.

As the continent battles the pandemic it is also crucial to step up the efforts to address other vaccine-preventable disease as well as bolster health systems to provide accessible, quality and affordable care.

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European Union funding boosts COVID-19 vaccination in Africa - WHO | Regional Office for Africa

Covid-19 Vaccine Apartheid Is Exacerbating Global Inequalities: UN – Common Dreams

March 29, 2022

The highly uneven global distribution of Covid-19 vaccines is exacerbating deadly inequalities betweenand withincountries, threatening to undermine socio-economic gains throughout the developing world, the United Nations warned Monday.

"The speed with which the world gets vaccinated in 2022 is critical to avoid more lost ground in contexts where progress is needed the most."

Two years into a pandemic that has killed millions, 2.8 billion people91% of whom reside in low-income nationshave yet to receive their first lifesaving shot, according to a new analysis released this month by the U.N. Development Programme (UNDP).

Although there has been a substantial increase in the total number of Covid-19 vaccines administered over the past several months, the allocation of doses remains starkly unequal. Of the 10.7 billion jabs given out worldwide, just 1% have gone into the arms of people in low-income countries, the UNDP found.

In addition to giving the coronavirus more opportunities to circulate among unprotected populationsincreasing the likelihood of new, potentially vaccine-resistant variants emerging and further prolonging the global public health emergencyvaccine inequity has harmed national economic recovery efforts, thereby widening "the poverty gap between rich and poor countries" and worsening inequalities within them, said the UNDP.

As of last month, 50 out of 54 countries in Africa were not on track to reach the World Health Organization's (WHO) target of inoculating 70% of their populations by mid-2022.

"Most of the vulnerable countries are found in Sub-Saharan Africa, including Burundi, the Democratic Republic of the Congo, and Chad, where less than 1% of the populations are fully vaccinated," said the UNDP. "And outside of Africa, Haiti and Yemen are still to reach 2% coverage."

Inside each nation, "the pandemic is hitting vulnerable and marginalized groups hardest," the UNDP continued. "Progress in education completion is expected to be reversed, especially among children from the poorest households. Gender disparities are increasing, with spikes in gender-based violence and less than 20% of countries' pandemic support geared towards women. And informal workers have been disproportionally hit by extended lockdowns."

Using data from the Global Dashboard of Vaccine Equity, developed by the UNDP, WHO, and the University of Oxford, the analysis shows how inequitable access to Covid-19 vaccination "will not only affect poorer countries disproportionally in terms of health, but also have a profound and lasting impact on their socio-economic recovery."

Lamenting numerous "lost opportunities," the UNDP found that "if low-income countries had the same vaccination rate as high-income countries in September last year (54%), they would have increased their GDP by US$16.27 billion in 2021, which could have been used to address other pressing development challengeseducation, healthcare, [and] energy for all, for example."

Ethiopia, the Democratic Republic of the Congo, and Uganda have lost the most potential income as a result of what global health justice campaigners have called "vaccine apartheid" during the pandemic, according to the U.N.

While governments in wealthy nations have been better able to soften the financial impact of the pandemic by providing vaccines and "more comprehensive and longer-lasting economic support" to various kinds of workers, the world's 1.6 billion informal workers "saw their earnings decline by 60% in 2020," and in "some countries with a large informal sector, like Uganda, Bangladesh and Colombia, experienced a significant increase in the number of days of complete lockdown in 2021, before reaching higher vaccination coverage," the UNDP pointed out.

"The speed with which the world gets vaccinated in 2022 is critical to avoid more lost ground in contexts where progress is needed the most," the agency wrote. "As many as 19 million people need to be inoculated each week in low-income countries to reach the 70% target by mid-2022, which represents an increase by over 800% compared to current rates."

"As many as 19 million people need to be inoculated each week in low-income countries to reach the 70% target by mid-2022, which represents an increase by over 800% compared to current rates."

As the UNDP explained, "reaching the 70% target means that countries that can least afford it will have to boost health spending by a disproportionate amount compared to richer countries." Whereas high-income nations have to increase healthcare spending by an average of just 0.8% to vaccinate 70% of their populations, their impoverished counterparts have to scale up expenditures by an average of 56.6% to achieve the same goal.

"For low-income countries, the spending required on vaccines equals 59% of the annual average investment needs to end extreme poverty by 2030 (SDG 1.1) or 89% of the average expenditure needs per year to ensure that all girls and boys can complete free, equitable, and quality primary and secondary education (SDG 4.1)," said the UNDP, alluding to Sustainable Development Goals (SDGs) that are being put on the back burner, possibly leading to what U.N. High Commissioner for Human Rights Michelle Bachelet earlier this month described as a "lost decade for development."

To prevent developing countries from accumulating more debt in the process, the UNDP endorsed financing vaccination campaigns through grants and concessions as recently proposed by the International Monetary Fund (IMF). The agency also emphasized the need to pay greater attention to the "logistics and planning needed to effectively distribute vaccines on the ground, especially in low-resource settings."

Although the UNDP has called for "urgent action to boost supply, share vaccines, and ensure they're accessible to everyone," the agency's new analysis doesn't mention potential solutions proposed by vaccine equity campaigners.

For instance, many experts, including former U.N. Secretary-General Ban Ki-moon, have demanded the temporary suspension of coronavirus-related intellectual property restrictions, which they say will enable qualified manufacturers around the world to boost the supply of generic tests, jabs, and treatments, paving the way for more equitable distribution.

Others have argued that while the fight for a robust patent waiver continues, the United States and other rich governments should invest in the creation of regional manufacturing hubs to ramp up the public production of vaccines. The U.S., for instance, owns a patent underlying mRNA technology, giving it significant leverage to share knowledge over the objections of profit-maximizing pharmaceutical companies.

The UNDP estimates that the cost of vaccinating 70% of the world's population by mid-2022 to be $18 billion, while Public Citizen has developed a blueprint showing how the U.S. could produce enough doses to protect the world from Covid-19 for $25 billion, or roughly 3% of President Joe Biden's latest military budget request of $813 billion.

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Covid-19 Vaccine Apartheid Is Exacerbating Global Inequalities: UN - Common Dreams

The Bottom Line: Bill seeking to prevent COVID-19 vaccination mandates by employers dies in committee – The Lane Report

March 29, 2022

With few days left in the 2022 legislative session, a bill seeking to fight vaccine mandates died in a Senate committee.

House Bill 28, sponsored by Rep. Savannah Maddox, was originally drafted to state private and public entities could not mandate the COVID-19 vaccine.

However, the bill was altered throughout the legislative process to remove private employers and was left with language barring public colleges and universities as well as local and state governments from requiring disclosure of a persons coronavirus-related immunization status. It also sought to ban vaccine passports.

While it was passed by a House committee and the full House, it failed in the Senate Health and Welfare Committee with only four yes votes.

Senate Health and Welfare Committee Chair Ralph Alvarado noted the sponsor had not done what he felt was the proper legwork in the Senate to get the bill passed but the legislation had been called at the sponsors request.

Unless the language of the bill is placed into another bill as a vehicle, it is dead for the 2022 session.

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The Bottom Line: Bill seeking to prevent COVID-19 vaccination mandates by employers dies in committee - The Lane Report

Will an Italian Convent be Closed for Opposition to COVID-19 Vaccines? – National Catholic Register

March 29, 2022

According to Mother Caterina, there is no other explanation for the closure than the refusal of the five remaining sisters to receive the COVID-19 vaccine.

PERUGIA, Italy The head of a cloistered Benedictine convent in Perugia, central Italy, has said that her community will be closed because the nuns opposed the COVID-19 vaccine.

Speculation about the closure of the Monastery of Santa Caterina has swirled since the news emerged that the Vatican had conducted an apostolic visitation, or inspection. But the local archdiocese told CNA that it knew nothing about the convents possible closure.

In an interview with the website Nuova Bussola Quotidiana, the abbess said that the only reason she was given for the closure was that the five resident nuns did not want to be vaccinated.

Shortly after mid-February, there was the apostolic visit immediately after the report was sent, said Mother Caterina. Now we are waiting for the response from the Congregation for Institutes of Consecrated Life and Societies of Apostolic Life.

She said that she had learned of the visitation from Cardinal Gualtiero Bassetti, the archbishop of Perugia-Citt della Pieve, but only when she went to him to have a document signed. The cardinal said he did not know the reasons for the visitation and had simply been informed that it was taking place.

The apostolic visitor was Mother Cristina Ianni of the Poor Clares of Orvieto.

The Monastery of Santa Caterina is a historic building. It was the seat of the Poor Clares as early as the 13th century and was initially dedicated to St. Giuliana (Juliana of Nicomedia). In 1649, with the transfer of the Benedictine nuns of Santa Caterina Vecchia, it took its current name.

After the unification of Italy in the 19th century, part of the monastery was redesigned. First, it served as a match factory. Today, it houses the offices of the Superintendency of Architectural Heritage.

According to Mother Caterina, there is no other explanation for the closure than the refusal of the five remaining sisters to receive the COVID-19 vaccine.

She said that, in her view, the possible closure was not due to the small number of nuns, although Pope Francis 2016 apostolic constitution Vultum Dei quaerere encourages small monasteries to close or federate.

In a press release, the archdiocese of Perugia-Citt della Pieve noted that visitations are initiated by the Congregation for Institutes of Consecrated Life and Societies of Apostolic Life. Therefore, nothing could be known for certain about the imminent closure of the monastery, much less on the fact that the reason for a possible closure is due to the non-vaccination of the nuns present there against COVID-19.

The archdiocese stressed that Cardinal Bassetti never intervened on the internal issues of the monastery and not even on issues relating to the vaccination of the nuns.

The archdiocese denied journalistic insinuations that the nuns were being transferred because they refused to undergo vaccination.

The March 24 statement also underlined that the cardinal had not yet received any reports regarding the state of the monastery from a spiritual, liturgical, and economic point of view.

The archdiocese said that the monastery is owned by the Benedictine Order which has the exclusive right regarding its possible destination or alienation following the closure of the monastery. Therefore any involvement of the archdiocese in this regard is devoid of any foundation.

The statement also emphasized how precious the monastic presence is for the life of the Church and how it has always tried to accompany it with paternity and respect and enhance it in all its charismatic richness.

Therefore, it can only experience this moment with pain, which instead of building ecclesial unity and communion, wounds it with news and insinuations that do not correspond to the reality of the facts, it concluded.

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Will an Italian Convent be Closed for Opposition to COVID-19 Vaccines? - National Catholic Register

Kyrie Irving played in his first home game of the season after New York City expanded its Covid-19 vaccine exemption – CNN

March 29, 2022

Irving racked up 16 points and 11 assists in the Nets' 119-110 loss to the Charlotte Hornets at the Barclays Center.

His return to the hardwood in Brooklyn came after New York Mayor Eric Adams announced Thursday he would allow New York-based professional athletes and performers to be exempt from the city's vaccine mandate for workers.

The policy kept Irving, a seven-time All-Star guard who chose not to receive a Covid-19 vaccine, from playing in 35 home games the Nets have played since the NBA season began in October. He has been playing with the team on the road.

"I don't take it for granted what happened tonight. It was historic and I'm grateful that I got a chance to be out there with my brothers and just leave it all out there," Irving said after the game.

The Nets have seven remaining games in the NBA regular season, five of which will be played at the Barclays Center. The team's next home game is Tuesday against the Detroit Pistons.

Adams said he expanded the vaccine exemption in part because the city's economy -- including vendors and businesses that surround the city's venues -- thrives best when all its stars attract people to those places. The city's multibillion-dollar tourism industry, he said, was still suffering from losses caused by the pandemic.

He also said he was doing it out of fairness -- to put New York City-based performers "on a level playing field" with visiting performers, who were already exempt from the mandate, and because the city is now a "low-risk (Covid-19) environment."

"We're not doing it because there are pressures to do it. We're doing it because the city has to function," Adams said Thursday.

The expansion of vaccine exemptions means all New York Yankees and Mets players can participate in their home openers next month regardless of their Covid-19 vaccination status.

Details about how many Yankees and Mets have not received a Covid-19 vaccine weren't immediately available.

At Thursday's news conference, Yankees president Randy Levine said a "few" of his team's players were unvaccinated.

"You're going to have to live with 'few,' and I can't give you individuals," Levine said, citing privacy laws and rules in Major League Baseball's operating agreement with players.

Mandate still applies to other city workers

The expanded vaccine exemption covers city-based singers and other entertainers, but the decision frustrated unions of other types of workers who argued the wider mandate isn't necessary and people fired for not adhering to it should be reinstated.

"If the mandate isn't necessary for famous people, then it's not necessary for the cops who are protecting our city in the middle of a crime crisis," said Patrick J. Lynch, president of the Police Benevolent Association of the City of New York. He noted the union has been "suing the city for months over its arbitrary and capricious vaccine mandate."

A United Federation of Teachers spokesperson also took issue with Adams' move.

"Vaccinations are a critical tool against the spread of Covid, and the city should not create exceptions to its vaccination requirements without compelling reasons," the UFT spokesperson said. "If the rules are going to be suspended, particularly for people with influence, then the UFT and other city unions are ready to discuss how exceptions could be applied to city workers."

The executive director of District Council 37, a union of public employees, said "thousands of city workers lost their jobs over the vaccine mandate."

"These are the same essential workers who kept the city going during the height of the pandemic. They deserve the respect and dignity of having their jobs back," the DC 37 official, Henry Garrido, said. "They deserve to be treated equally to their private sector counterparts. We demand that those who lost their job over the mandate be reinstated."

Adams said the city is not reviewing the cases of 1,400 municipal employees who were terminated for not getting vaccinated. The figure includes those who were hired following the mandates with the agreement of getting vaccinated, but ultimately chose not to.

He said officials would continue to promote Covid-19 vaccines, and he hoped the vaccination rates of all the city's sports teams would reach 100%.

"Kyrie ... get vaccinated. Nothing has changed," Adams said Thursday.

CNN's Jason Hanna, Kristina Sgueglia and Jack Bantock contributed to this report.

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Kyrie Irving played in his first home game of the season after New York City expanded its Covid-19 vaccine exemption - CNN

Recycling old antivax tropes as bioethics-based arguments against COVID-19 vaccination for children – Science Based Medicine

March 29, 2022

Regular readers might be getting tired of my pointing out how theres nothing new under the antivax sun in terms of deceptive arguments, conspiracy theories, and tropes designed to argue against vaccinating. However, the COVID-19 pandemic introduced these talking points to a much large audience than had ever seen them before so I considered it my duty to educate our readers and to point out that none of the antivaccine misinformation that has hit us like a tsunami since COVID-19 vaccines first entered large clinical trials in the summer of 2020 is anything new. It just seems new if you havent seen it before. Examples include, of course, misinformation claiming that the vaccine kills based on misinterpretation of the VAERS database; that it sterilizes our womenfolk; that it sheds and endangers the unvaccinated; and that it causes cancer, none of which are anything new. Even the claim that it permanently alters your DNA, although it might appear like a new talking point based on the fact that Pfizer/BioNTech and Moderna COVID-19 vaccines were the first successful translations of mRNA technology into a clinical product, if you look really hard, is not a new claim. (Transhumanism, anyone?) As Charles Pierce likes to say, history is so cool. In this case, though, Id add: Its only cool and useful if you know about it and can use it to counter the pernicious misinformation about vaccines of the sort published by, for example, The Wall Street Journal and deconstructed by Jonathan Howard yesterday.

Last week the journal Bioethics published another example of how everything old is new again in the form of an article titled Against COVID-19 vaccination of healthy children. It might as well have been titled Against vaccination of healthy children, because pretty much every one of the arguments presented could be used to argue against long-accepted childhood vaccines that have been mandated as a prerequisite for school enrollment in the US for decades. Ill explain in a moment, but, given that this is presented as piece of serious scholarship, I wondered who was behind it. It turned out to be from a last-year graduate student named Steven R. Kraaijeveld at Wageningen University, the Netherlands, and Associate Fellow at the Research Consortium on the Ethics of Socially Disruptive Technologies. Its noted in the Biographies section that his PhD dissertation is on the ethics of vaccination. His research focuses on philosophy and ethics of technology, medical ethics, public health ethics, and moral psychology. After reading this article, Id say that he needs to go back to the drawing board, particularly given the Tweets with which he bragged about his paper on Friday:

In the thread, as he lists his reasons for arguing against the both routine and mandatory COVID-19 vaccination of healthy children he brags about all the data that back up his ethical conclusions, after, of course regurgitating the health freedom and parental rights arguments that have long been a staple of antivaccine activists going back decades:

Mr. Kraaijevelds co-authors include Rachel Gur-Arie, PhD, MS, Hecht-Levi Postdoctoral Fellow in Ethics and Infectious Disease at the Berman Institute of Bioethics at Johns Hopkins University, and Euzebiusz Jamrozik, MD, PhD, practicing Internal Medicine Physician and fellow in Ethics and Infectious Diseases at Ethox and the Wellcome Centre for Ethics and Humanities at the University of Oxford, as well as Head of the Monash-WHO Collaborating Centre for bioethics at the Monash Bioethics Centre. Youd think that at least Dr. Jamrozik would be aware of the antivaccine tropes being recycled in this graduate students paper, but apparently not. Ive found that, depressingly, a lot of academics who actually work on infectious diseases and vaccines are blissfully unaware of common antivaccine tropes, which leads them to regurgitate them inadvertently in a much more palatable, academic-seeming form. This is what this paper does.

In the case of this article, its hard not to think of Bioethics like this.

In fairness, I will give the authors a modicum of credit in that they seem to realize that their arguments could be used to argue against other childhood vaccines. They even say so in the introduction, claiming that theyll show you why the arguments in favor of routine vaccination of children against COVID-19, arguments that they find compelling for other childhood vaccines, dont hold up for COVID-19 vaccines. In fact, as Ill show, the arguments they make against the key pillars of the case for vaccinating children against COVID-19 could just as easily be deployed against many, if not most, childhood vaccines currently in use and long accepted.

Kraaijeveld notes:

This article presents an analysis of the ethics of vaccinating healthy children against COVID-19 by responding to the strongest arguments that might favor such an approach.5 In particular, we present three arguments that might justify routine6 COVID-19 vaccination of children, based on (a) an argument from paternalism, (b) an argument from indirect protection and altruism, and (c) an argument from the global public health aim of COVID-19 eradication.7 We offer a series of objections to each respective argument to show that, given the best available data, none of them is tenable. These arguments, which might be compelling for childhood vaccination against other diseases and in different circumstances,8 do not appear to hold in the case of COVID-19 with the currently available vaccines. Given the present state of affairs and all things considered, COVID-19 vaccination of healthy children is ethically unjustified.

If one accepts our conclusion that routine vaccination of healthy children against COVID-19 is ethically unjustified, then it follows that coercion, which is an ethically problematic issue in itself, is even less warranted. Nonetheless, mandatory vaccination of healthy children against COVID-19 is already being consideredand, in some places, implementedas a way of increasing vaccine uptake.9 We therefore also provide two objections specifically against making COVID-19 vaccination mandatory for children, which center on additional ethical concerns about overriding the autonomy of parents and legal guardians and of children who are capable of making autonomous decisions. If vaccinating healthy children against COVID-19 is ethically problematic, then coercing vaccination is even less acceptablebut even if vaccinating healthy children against COVID-19 should at some future point be considered more defensible (e.g., should a much more favorable costbenefit analysis emerge), important ethical objections against coercive mandates will still remain.

As I said before, Mr. Kraaijeveld is recycling the health freedom and parental rights arguments that portray any attempt to require vaccines for children before entering public school or daycare facilities as an unacceptable fascistic assault of freedom. Its a very old antivaccine argument that takes a reasonable debate about the limits of what can be mandated in the service of public health and turns it into a Manichean view that portrays any sort of mandate or even mild coercion as evil. One has only to look at the Defeat the Mandates rally held in Washington, DC in January (with a repeat scheduled for Los Angeles in April) to see this argument taken to an extreme.

Its true that Defeat the Mandates tends to include more than vaccine mandates, but it also adds a healthy dash of parental rights to the rhetoric of health freedom, all with a Boomer-friendly design (note the font) reminiscent of Woodstock.

Lets look at Mr. Kraaijevelds main arguments one by one.

Mr. Kraaijeveld begins by characterizing the appeal to paternalism thusly:

The first argument in favor of childhood vaccination for COVID-19 derives from paternalistic considerations and holds that routine vaccination of healthy children is justified because it is in the best interests of the would-be vaccinated children. The argument from paternalism suggests that COVID-19 vaccination will, all things considered, benefit children the most (or cause them the least harm). Given that routine vaccination is the most effective way to ensure vaccine uptake, it is therefore justified for the sake of the health and well-being of children themselves.

Unsurprisingly, his objections are twofold:

Both Dr. Howard and I have been repeating for months now how these claims are not only wrong, but echo the same claims made by antivaxxers about the MMR vaccine. Whenever the argument that we shouldnt vaccinate children against COVID-19 because the disease isnt that dangerous to children (i.e., quite literally, doesnt kill that many children), Im reminded of the appeal to the Brady Bunch commonly repeated by antivaxxers in 2015. Ill discuss that more in a moment, but first lets see what Mr. Kraaijeveld actually argues:

According to the best available data, healthy children are at a much lower risk of severe illness from COVID-19 and are less susceptible to infection than older adults.10 In contrast to many other vaccine-preventable diseases, healthy children are at low risk of severe COVID-19 infection, morbidity, and mortality.11 Hospitalization of children with COVID-19 is rare, although emerging data suggest that children with severe underlying comorbidities are at higher risk.12 Deaths among healthy children due to COVID-19 are very rare; for example, a large study in Germany found no deaths among children aged 511 without comorbidities.13 We agree with the assessment that COVID-19 is not a pediatric public health emergency.14

That last citation (#14) is to an article by Drs. Wesley Pegden, Vinay Prasad, and Stefan Baral published in May 2021 arguing that COVID vaccines for children should not receive emergency use authorization. Dr. Howard recently discussed that article and its many flaws in great detail in follow-up to his original discussion of the article last year, which means I dont have to now. Read the articles for the details, but, in brief, Pegden et al. presented a case that made COVID-19 appear essentially harmless to healthy children (much as antivaxxers had long claimed that measles, chickenpox, and the like are essentially harmless to healthy children for years before) while leaving out information about how effective the vaccines were in children. Lets just echo what Dr. Howard said by listing again some of his key bullet points (remember, this was May 2021 and lots more children have been hospitalized and died since then in the US):

That sounds serious to me, and, remember, the Pegden et al. article was published almost 11 months ago, and, as our very own Dr. Howard pointed out, there was definitely some cherry picking going on here:

And also, others pointed out how cherry picked Mr. Kraaijevelds citations were:

Actually, it wasnt just cherry picking; it was misrepresentation, too:

Id also suggest that Mr. Kraaijeveld look at who is leaping to his defense. Personally, Id be embarrassed if I had people like this defending me:

If you want to see how bad Mr. Kraaijevelds arguments are, look no further than this passage:

Overall, the burden of COVID-19 in children appears to be similar to or lower than that of typical seasonal influenza in the winter (unlike the much higher disease burden of COVID-19 in adults).16 In 2020, 198 children aged <17 officially died of COVID-19 in the United States.17 In 2021, with Delta being the predominant variant, that number increased to 378,18 which is comparable to the official number of children aged <17 who died in the 20182019 influenza season in the United States (i.e., 372).19

Notice how every time the claim is made that COVID-19 is much less deadly (or at least no more deadly) than the flu in children (even, as I note, routine yearly vaccination against the flu is recommended for children), its always the 2018-2019 flu season thats cited, Always. Of course, that was the last complete flu season before the pandemic, which means that citing it is citing a season with zero mitigations of the likes that the pandemic brought us. There were no mask mandates, no business shutdowns, no virtual schooling, and no social distancing. Its an intellectually dishonest comparison of apples to oranges worthy of antivaccine activists (which is why Mr. Kraaijeveld really shouldnt have used it), and, as Dr. Howard put it, 1,200 is more than six. Basically, in the same environment, with mask mandates and mitigations, COVID-19 was much more deadly to children than the flu. Mr. Kraaijevelds argument boils down to the same argument antivaxxers make, namely that routine (or even mandated) vaccination of children against COVID-19 is unnecessary because its more or less harmless to healthy children and not that many children die of it. Again, it used to be accepted that children arent supposed to die if we can reasonably prevent it (which we can with COVID-19 vaccines), but arguments like Mr. Kraaijevelds amount to a shrugging of the shoulders over a level of child death that used to be considered unthinkable, even though 20% of COVID-19 deaths occur in children with no underlying conditions. Some ethics!

This brings us back to the Brady Bunch.

I last discussed the Brady Bunch gambittwo weeks ago. It was basically an antivax trope pioneered several years ago by antivaxxers about the measles. Theyd point to a 1969 episode of the classic sitcom The Brady Bunch in which all six kids (and, ultimately, Mike and Alice, who, it turns out, had never had the measles as children) caught the measles. The whole situation was played for laughs, with the kids happily staying home and playing games, the only evidence that they were ill being phony-looking red spots on their faces and limbs. It wasnt just The Brady Bunch either. Even though its only two weeks since I last cited it, heres a 2014 YouTube video that was making the rounds then:

You get the idea, I think. I consider Mr. Kraaijevelds paper to be an academic version of the Brady Bunch gambit, which is why Ill take this opportunity to point out yet again that according to the CDC, before the vaccine, 48,000 people a year were hospitalized for the measles; 4,000 developed measles-associated encephalitis; and 400 to 500 died. By any stretch of the imagination that was a significant public health problem, and the introduction of the measles vaccine in 1963, followed by the MMR in 1971, made it much less so, bringing measles under such control that it became very uncommon and deaths from it rare. As Dr. John Snyder reminded us nearly 13 years ago in his response to Dr. Sears making the same arguments in his vaccine book that touted an alternative vaccination schedule, measles is not a benign disease, regardless of what popular culture thought of it 50 or 60 years ago. (More recent data show that a severe complication of measles, subacute sclerosing panencephalitis (SSPE), is more common than we used to think.) Meanwhile, over 13 years ago Dr. Sears was claiming that the risk of fatality from measles is as close to zero as you can get without actually being zero. Sound familiar? This is basically the same argument that Mr. Kraaijeveld is making for COVID-19, which has killed over 1,300 children in the US since the pandemic hit, arguably more than the average yearly toll of measles before the vaccine.

Mr. Kraaijeveld also invokes another common antivax argument:

Furthermore, post-infection immunity has been found to be at least as effective as vaccination at protecting against disease due to reinfection with COVID-19.24 An increasingly large body of evidence suggests that immunity after previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is at least as robust as vaccine-induced immunity.25 Childhood exposure to SARS-CoV-2, which, as previously discussed, is generally associated with mild viral illness, may offer protection against more severe illness in adulthood.26 To date, hundreds of millions of children have already been infected with COVID-19. For children with immunity from previous infection, the potential benefits of vaccination are likely to be lower than for children without immunity

Ill give Mr. Kraaijeveld credit for using the preferred term post-infection immunity rather than natural immunity, but this, too, is an old antivax argument, namely that natural immunity is better than (or at least as good as) vaccine-induced immunity. Its an argument that I first encountered over 20 years ago, which was when I first started taking a serious interest in the antivaccine movement. Sometimes it got really ridiculous too. Does anyone remember the book Melanies Marvelous Measles 11 years ago? It was a childrens book that argued that measles was not only not harmful but that it was good for children because it built natural immunity. Indeed, its blurb read:

This book takes children aged 4 10 years on a journey of discovering about the ineffectiveness of vaccinations, while teaching them to embrace childhood disease, heal if they get a disease, and build their immune systems naturally.

Actually, measles is worse than we thought in that it causes immune amnesia that suppresses immune memory and makes one susceptible to other infections for 2-3 years. You know why natural immunity isnt better than vaccine-induced immunity? Its because achieving natural immunity requires that one actually suffer through the disease and risk its complications, up to and including death.

I like to ask everyone, including Mr. Kraaijeveld, who argues against routine vaccination of children against COVID-19 because it isnt that dangerous to them: Why arent you arguing against routine vaccination against measles? The death toll among children due to COVID-19 over the last two years (>1,300) translates to a higher yearly death toll than the measles produced in the years right before the vaccine. What about chickenpox, which used to kill only around 100 children a year before the vaccine? Why arent you arguing against the varicella vaccine?

Oh, thats right. Its because the COVID-19 vaccine is supposedly so much more dangerous:

The case for vaccinating healthy children against COVID-19 for their own sake is undermined by uncertainty; that is, by the currently poorly characterized potential for rare, harmful outcomes associated with the vaccines in children. Public safety data from the Pfizer-BioNTech clinical trials in children included 2,260 participants aged 12 to 15, of which 1,131 received the vaccine.37 In addition to a small sample size, the trial follow up period was of short duration; therefore, no reliable data presently exist for rare or longer-term vaccine-related harms.38 Though common adverse events occurring less than 6 months after vaccination may be ruled out, the risks of rare or delayed adverse outcomes can simply not yet be evaluated.39 Should vaccine harms occur, they will be revealed in the general pediatric population only after thousands or millions of children are already vaccinated, which would also risk seriously undermining vaccine confidence. The restriction of AstraZeneca vaccines to older age groups due to blood clotting events early on in the COVID-19 vaccination rollout, as well as reports of increased rates of vaccine-related myocarditis among younger age groups illustrates that rare risks are sometimes more common in younger age groups and might sometimes outweigh benefits in children.40 Severe cardiac manifestations such as myocarditis and pericarditis are now recognized as rare risks of the COVID-19 vaccines.41 Myocarditis-induced deaths following COVID-19 vaccination have been documented in adolescents as well as in adults.42

This is a classic antivax argument, namely that the vaccine is more dangerous than the disease. Of course, if the vaccine truly is more dangerous than the disease, then that is a compelling argument. However, as weve discussed many times (particularly Dr. Howard), this is not the case with COVID-19 vaccines. Even the cases of two adolescent deaths after vaccination cited by Mr. Kraaijeveld are not nearly as clearcut as portrayed, as pediatric cardiologist Dr. Frank Han discussed, noting that dilation of the heart (found in one boy) doesnt occur within days and the autopsy findings were missing some key pieces of information that would definitively suggest the vaccine as the cause.

The speculation about potential long term effects is also a common antivaccine trope. Antivaxxers, failing to be able to make the case that routine childhood vaccines are more dangerous than the diseases that they vaccinated against, often pivot to handwaving about unknown (and undescribed and unproven) long term effects. Before COVID-19, those long term adverse events were autism, autoimmune disease, cancer (still a favorite for COVID-19 vaccines), and pretty much every major chronic illness. (Indeed, antivaxxer Robert F. Kennedy, Jr. came up with the false claim that the current generation of children is the sickest generation, largely due toyou guessed it!vaccines.) The last time I dealt with the claim of long term adverse events (i.e., greater than a few weeks to six months after vaccination), I noted that they were very rare, so rare that Paul Thacker, for instance, had to do incredible contortions to find very rare cases that occurred only in the special case of immunosuppressed children and cite narcolepsy after the H1N1 vaccine Pandemrix, which actually occurred within weeks after vaccinationhardly long term.

So this section is basically one antivax argument that the vaccine is more dangerous than the disease. Its not; so Mr. Kraaijevelds ethical argument falls apart. Next up, he appeals to a lack of sterilizing immunity.

The next arguments for vaccination against COVID-19 that Mr. Kraaijeveld takes are all based on the observation that COVID-19 vaccines do not produce sterilizing immunity; i.e., they do not completely prevent infection and transmission, although he does concede that they are quite effective at preventing severe disease, hospitalization, and death. Based on this observation (primarily), he takes on the argument from indirect protection and altruism and the argument from global eradication. Ill start with the latter first, because in its service he makes an argument that caused me, literallyand I do mean literallyto facepalm as I read it. Specifically, he objects to claims that ongoing transmission will:

Mr. Kraaijeveld objects to the first argument by pointing out that evolutionary fitness of an infectious virus is determined more by increased transmissibility rather than virulence, which is true as far as it goes, although he cites a 2020 paper making the argument that there was not yet evidence of SARS-CoV-2 variants with increased transmissibility. (Those would arrive a few months later in the form of the Delta and Omicron variants, the Delta variant being more transmissible than the original Wuhan strain and the Omicron variant being more transmissible than the Delta variant.) Howeverand heres where the facepalm came in as I readthat is actually a strong argument for doing everything reasonable, especially vaccination, to decrease the level of transmission to as low a level as is feasible, in order to decrease the likelihood of more transmissible variants arising. Again, as people making these arguments always seem to do, Mr. Kraaijeveld is falling prey to the Nirvana fallacy, in which an imperfect intervention is portrayed as a useless one. When someone like this argues that COVID-19 vaccines do not prevent infection or transmission, it implies that the vaccines dont prevent infection or transmission at all, which is nonsense. Of course they do; theyre just not 100% effective (or, since the rise of Delta and Omicron even close to it).) The way to look at it is that the vaccines are less good at preventing infection and transmission than they are at preventing serious disease and death, not that they dont prevent transmission or infection at all.

What flows from Mr. Kraaijevelds Nirvana fallacy is predictable. He argues, as I mentioned above, that mass vaccination of children will not contribute to preventing the development of more harmful variants. I note that, even as he observes that virulence and transmissibility are often incorrectly conflated, Mr. Kraaijeveld himself seems to be doing the same thing as he in essence argues against a straw man of the real argument, that decreasing transmission is useful in terms of controlling the disease, even if the vaccines dont produce anything near sterilizing immunity. He also argues:

The notion that unbridled transmission would make the virus more likely to escape vaccine-derived immunity makes the eradication argument either self-defeating or incredibly costly. Aside from the fact that current vaccines do not prevent infection or transmission, if certain variants really are highly efficient at evading vaccine-derived immunityor, worse still, if more variants continuously evolve to evade vaccines more efficientlythen attempts at eradication through global vaccination, and the strong evolutionary selection pressures this entails, will be met with diminishing returns for the costs of such a program.

Its also rather funny how Mr. Kraaijeveld fails to note that these new variants are also pretty good at evading post-infection natural immunity as wellpossibly even as good as they are at evading vaccine-induced immunityto the point where its increasingly being concluded that, while its better to prevent COVID-19 with vaccination, if you do get it hybrid immunity (a combination of infection-induced and vaccine-induced immunity from getting the vaccine after youve recovered) is better at preventing the disease than either alone. I also note that there are few areas in the world where the vaccination rate among adults (much less among children) is anywhere near high enough to result in significant selection for variants that evade the immune response; what we are seeing is primarily a selection for increased transmissibility due to wide and largely uncontrolled circulation of the coronavirus among large populations.

Mr. Kraaijeveld also argues that children are not a major driver of COVID-19 transmission, thus making vaccinating healthy children pointless, because, according to him, COVID-19 is not dangerous to healthy children. One notes that there is more cherry picking here, given that all the studies he cites are pre-Delta and pre-Omicron. Moreover, more recent studies showing that mask mandates significantly decreased transmission suggest that schools are not as insignificant a source of COVID-19 circulation as Mr. Kraaijeveld would argue.

The last part of Mr. Kraaijevelds paper opposes any sort of mandates for COVID-19 vaccines for children that are straight from the antivax playbook. First, the appeal to parental rights:

Mandates for children to be vaccinated against COVID-19 would limit and, depending on their nature, even override the autonomy of parents and guardians to make decisions about the health of their children. This requires ethical justification as such, but it demands stronger justification in proportion to the level of coercion that mandates would involve.100 When mandates are in place, the actors who make decisions for the health and well-being of children de facto become governments and public health officials rather than parents, although less coercive measures (e.g., small fines) might allow some parents to opt out and thereby retain decisional autonomy.101

I have to wonder right here if Mr. Kraaijeveld understands how mandates work for children, in the US at least. Here, the mandate is that children require certain vaccines to attend school, but there is no legal penalty for not vaccinating ones children other than not being allowed to enroll them in school. Certainly, there are no fines, and its pretty rare that parents are investigated by child protective services for not vaccinating their children. (Usually, such investigations involve far more than just not vaccinating.) He also seems unaware that most states allow religious and philosophical exemptions to these mandates, in addition to medical exemptions. In the US, at least, the coercion that he decries isnt much in the way of coercion at all, which makes me wonder why he doesnt think that, in the US at least, mandating COVID-19 vaccines for school is acceptable. Oh, wait. As discussed above, he echoesunknowingly, I hope, but possibly knowingly I fearantivaccine talking points about them, such as the claims that COVID-19 doesnt harm healthy children, that the vaccine is more dangerous than the disease, that it doesnt produce sterilizing immunity and is therefore useless in contributing to herd immunity, and other arguments.

He also goes straight into Great Barrington Declaration/Urgency of Normal territory of focused protection:

For COVID-19, vaccines are safe and effective in higher-risk groups, including older adults and the immunocompromised,59 and significantly reduce the risk of severe illness even when vaccinated groups are exposed to substantial community transmission.60 While there are some people for whom the current COVID-19 vaccines are contraindicated (e.g., those with severe allergies), this group appears to be small.61 It is therefore not the case that vulnerable groups cannot protect themselves, which would make routine vaccination of less vulnerable groupschildren, in this casemore compelling. Moreover, as argued above, children are not major drivers of COVID-19 transmission. As such, there is no strong ethical justification for COVID-19 vaccination of healthy children for the sake of vulnerable groups.

This is, in essence, the same argument that Great Barrington Declaration authors make about all interventions to prevent the spread of COVID-19including masks, lockdowns, and vaccinesnamely that its possible to protect the vulnerable (focused protection) and that no intervention should be permitted that is not completely voluntary. Unsurprisingly, consistent with this Mr. Kraaijeveld is apparently not a fan of nonpharmaceutical interventions, such as masks and lockdowns, to slow the spread of COVID-19 either, viewing them as ethically problematic as well.

To summarize, Mr. Kraaijeveld argues that, because current COVID-19 vaccines do not produce sterilizing immunity, herd immunity is not achievable, and vaccinating children doesnt protect others, nor would vaccinating them prevent the evolution of more harmful and/or immune-evading variants, and, as a result, vaccinating children is not ethically supportable, and vaccine mandates of any kind for COVID-19 are completely unjustifiable from an ethical standpoint. Of course, he fails to mention that most vaccines do not produce sterilizing immunity. Its not as though this hadnt been discussed at the time the vaccines were being rolled out or that scientists hadnt recognized that COVID-19 vaccines were unlikely to produce true sterilizing immunity. Its just plain incorrect to argue that you have to have sterilizing immunity for a vaccine to contribute to herd immunity or even the elimination of a disease. For example, the smallpox vaccine did not produce sterilizing immunity; yet, as has been observed, it was crucial in eradicating smallpox. Neither the Salk (inactivated) nor the Sabin (live attenuated) polio vaccine produces sterilizing immunity, but the global eradication of polio is within reach, thanks to the vaccines:

Also, while were on the topic of polio, it turns out that the same appeal to the disease doesnt kill that many children argument can be made for polio:

One wonders whether Mr. Kraaijeveld similarly questions whether routine polio vaccination is advisable, as well. Just as most of his arguments could be used against routine measles vaccination, similarly most of them could also be used against polio.

Or rotavirus:

The case of rotaviruswhich causes severe vomiting and watery diarrhea and is especially dangerous to infants and young childrenis fairly straightforward. Vaccination limits, but does not stop, the pathogen from replicating. As such, it does not protect against mild disease. By reducing an infected persons viral load, however, it decreases transmission, providing substantial indirect protection. According to the Centers for Disease Control, four to 10 years after the 2006 introduction of a rotavirus vaccine in the U.S., the number of positive tests for the disease fell by as much as 74 to 90 percent.

I mean

In other words, it is not a prerequisite that COVID-19 vaccines prevent transmission completely for them to be very valuable in curbing the pandemic. Moreover, newer generations of COVID-19 vaccines might actually be able to achieve sterilizing immunity. I also note that it has long been a favorite antivaccine argument to cite one vaccine in particular that doesnt provide sterilizing immunity, specifically the pertussis vaccine, whose immunity also wanes with time, like that from COVID-19 vaccines.

While issues of freedom and parental rights are issues of ethics and law about which there will always be some subjectivity based on differing belief systems and about which reasonable people can disagree, accurate science and data are required to have reasonable debates about how much the state should be allowed to infringe upon individual freedom and autonomy as well as parental rights. By massively downplaying the severity of COVID-19 in children in a manner that is, quite frankly, eugenicist in its emphasis on the disease supposedly being pretty close harmless to healthy childrennot to mention based on cherry picked data primarily from before the Delta and Omicron surgesand exaggerating the dangers of the vaccine, Mr. Kraaijeveld, whether he realizes it or not or will admit it or not, tilts the playing field in favor of his arguments in the same intellectually dishonest manner that antivaxxers have long done. He even recycles their arguments, as the way his appeal to the lack of sterilizing immunity due to COVID-19 vaccination and his claim that COVID-19 is close to harmless to most healthy children, both of which are old antivaccine claims used for a number of vaccines in the past, but particularly MMR, rotavirus, and varicella.

All of these reasons are why I now eagerly await Mr. Kraaijevelds next bioethical treatise arguing that we should not routinely vaccinate children against measles because the disease doesnt kill that many kids and that we shouldnt vaccinate against polio, pertussis, and most other childhood diseases because the vaccines dont produce sterilizing immunity and therefore cannot produce herd immunity or contribute to the elimination of the disease. After all, if hes going to recycle, he should go all-in and recycle everything.

Meanwhile, people who like Mr. Kraaijevelds message will go all Humpty Dumpty about words and argue that an article titled Against COVID-19 vaccination of healthy children is not actually arguing against vaccinating children against COVID-19:

Same as it ever was.

Link:

Recycling old antivax tropes as bioethics-based arguments against COVID-19 vaccination for children - Science Based Medicine

An update on Rhode Islands COVID-19 vaccination rates – The Boston Globe

March 29, 2022

Rhode Island fell below 60 hospitalizations of people with COVID-19 last week for the first time since Aug. 4, 2021, as cases especially severe cases across the country continue to dwindle.

But some readers have noted that the percentage of residents getting a vaccine booster shot (39.4 percent on Friday) has not risen as rapidly as the number of original shots has.

So I was curious how Rhode Island compares to the rest of the country.

It turns out that every state is dealing with this challenge. But just like with overall vaccination rates, Rhode Island has among the best booster rates, according to The New York Times tracker.

Rhode Island ranks No. 3 in the country for boosted rates among residents 65 and older (76 percent) and ages 18 to 64 (44 percent). Vermont (80 percent for ages 65 and older, 48 percent ages 18 to 64) is ahead in both categories.

Get Rhode Island News e-mailsSign up to get breaking news and interesting stories from Rhode Island in your inbox each weekday.

Puerto Rico leads the 18 to 64 category, at 49 percent, and Minnesotas 78 percent rate for people over age 65 places it No. 2.

At the other end of the spectrum, North Carolina (34 percent) and New Hampshire (36 percent) have the lowest booster shot rates in the country for residents age 65 and older, and Alabama and North Carolina are tied at 15 percent for the lowest in the country among residents ages 18 to 64.

For residents below the age of 18, Puerto Rico (20 percent) and Vermont (14 percent) are the only states with double-digit boosted rates. Rhode Island is at 8 percent.

Rhode Island is still holding regular vaccination clinics in communities across the state, including today in Providence and Pawtucket. You can check the entire list of clinics here.

This story first appeared in Rhode Map, our free newsletter about Rhode Island that also contains information about local events, data about the coronavirus in the state, and more. If youd like to receive it via e-mail Monday through Friday, you can sign up here.

Dan McGowan can be reached at dan.mcgowan@globe.com. Follow him on Twitter at @danmcgowan.

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An update on Rhode Islands COVID-19 vaccination rates - The Boston Globe

Covid-19 Cases, Testing and Omicron News: Live Updates – The New York Times

March 27, 2022

A common area at the Rochester Institute of Technology campus in Rochester, N.Y., in January.Credit...Libby March for The New York Times

With the pandemic entering a new phase in the United States marked by fewer precautions and the rise of the even more transmissible Omicron subvariant BA.2, the Biden administration has begun stressing the importance of mitigating the risk of indoor aerosol transmission, the primary driver of the pandemic.

The Environmental Protection Agency recently issued expert guidance to building managers, contractors and business owners, with two pages of recommendations that codify the best practices on ventilation, air filtration and air disinfection from academic experts and federal agencies of the last two years. The agency said that implementation could be underwritten with federal funds from the $1.9 trillion American Rescue Plan that President Biden signed into law a year ago.

Dr. Alondra Nelson, chief of the White House Office of Science and Technology Policy, said last week the guidance was part of an initiative called the Clean Air in Buildings Challenge. In a blog post titled, Lets Clear the Air on Covid, she cited the guidance and said, Now, we all need to work collectively to make our friends, family, neighbors, and co-workers aware of what we can do or ask for to make being indoors together safer.

For decades, Americans have demanded that clean water flow from our taps and pollution limits be placed on our smokestacks and tailpipes, she wrote in the post. It is time for healthy and clean indoor air to also become an expectation for us all.

U.S. federal health authorities were initially slow to identify airborne transmission of the virus. It was only in October 2020 that the Centers for Disease Control and Prevention recognized that the virus can sometimes be airborne, long after many infectious disease experts warned that the coronavirus traveled aloft in small, airborne particles. Scientists have been calling for a bigger focus on addressing that risk for more than a year.

The initiative is really a big deal said William Bahnfleth, a professor of architectural engineering at Penn State University and head of the Epidemic Task Force at the American Society of Heating, Refrigerating and Air-Conditioning Engineers. Its making the start that is often the most difficult part.

The society, whose roots go back to the dawn of the skyscraper in the late 19th century, is a global nonprofit technical society that, among other things, develops the consensus indoor air quality standards referenced in U.S. building codes.

Dr. Bahnfleths task force was created as the pandemic began sweeping the world in March 2020, and the new federal recommendations track closely with its guidance. He said that the pandemic had given momentum to the long overdue drive to improve the countrys mediocre air quality standards for buildings, noting that the existing standards had failed to protect people from coronavirus infections.

Viruses can travel in a variety of ways. Early in the pandemic, health officials assumed the coronavirus was transmitted primarily through droplets expelled during coughing or sneezing, as is the flu, or perhaps through contact with contaminated surfaces. But many scientists noted mounting evidence that the coronavirus was airborne, spreading in tiny particles adrift in indoor spaces.

Akin to the rating system for high-quality masks, whose high-tech filtering material trap at least 94 to 95 percent of the most risky particles (N95s, KN95s and KF94s), the filters used in building ventilation systems have what is known as a MERV rating. The higher the rating, which runs from 1 to 16, the better the filter is at trapping particles.

The new federal guidelines advise buildings to upgrade to at least a MERV 13 filter, which traps 85 percent or more of risky particles. Before the pandemic, many buildings used MERV 8 filters, which are not designed for infection control.

Long before the pandemic, studies showed that indoor air quality affects the health of students and workers. A Harvard study of more than 3,000 workers showed that sick leave increased by 53 percent among employees in poorly ventilated areas. Improved ventilation has also been associated with better test scores and fewer school absences.

Improving indoor air has benefits beyond Covid-19, Dr. Nelson wrote. It will reduce the risk of getting the flu, a common cold, or other diseases spread by air, and lead to better overall health outcomes.

March 27, 2022

Because of an editing error, an earlier version of this article misstated the amount of the American Rescue Plan that President Biden signed into law last year. It was $1.9 trillion, not $1.9 billion.

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Covid-19 Cases, Testing and Omicron News: Live Updates - The New York Times

COVID-19 Oral Treatment Being Evaluated by Adolescents and Children – Precision Vaccinations

March 27, 2022

(Precision Vaccinations)

New York-basedPfizer Inc. recentlyannounced today that it had initiated a Phase 2/3 study, EPIC-PEDS, to evaluate the safety, pharmacokinetics, and efficacy of PAXLOVIDin non-hospitalized, symptomatic, pediatric participants with a confirmed diagnosis of COVID-19 who are at risk of progression to severe disease.

The Phase 2/3 trial is an open-label, multi-center, single-arm study in approximately 140 participants under 18 years of age.

"Since the beginning of the pandemic, more than 11 million children under the age of 18 in the U.S.alone have tested positive for COVID-19, representing nearly 18% of reported cases and leading to more than 100,000 hospital admissions," commentedMikael Dolsten, Chief Scientific Officer and President, Worldwide Research, Development and Medical, Pfizer, in a press release issued on March 9, 2022.

"There is a significant unmet need for outpatient treatments that can be taken by children and adolescents to help prevent progression to severe illness, including hospitalization or death."

"PAXLOVID is already authorized or approved in many countries worldwide, with more than 1.5 million treatment courses delivered thus far and 30 million expected by July (2022) to help combat this devastating disease."

This clinical trial is essential as the SARS-CoV-2 virus variant known as BA.2 continues to spread in the U.S.

The U.S. HHS/ASPR confirmed on March 25, 2022, that based onin vitro assay data, these products (Paxlovid) are likely to retain activity against the BA.2 variant.

Additional COVID-19 oral treatment news is posted at PrecisionVaccinations.com/antivirals.

Note: This news article integrated and edited information for clarity and was manually curated for mobile readers.

Continued here:

COVID-19 Oral Treatment Being Evaluated by Adolescents and Children - Precision Vaccinations

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