Category: Corona Virus

Unvaccinated people are over 11 times as likely to die from COVID as vaccinated individuals,recent datafrom the Centers for Disease Control and Prevention shows. At last winters peak, when the vaccines were just rolling out, an average of 3,400 people were dying of the illness each day. Now that average, while still alarming, hovers around 1,000.

And though the vaccines are not 100 percent effective at preventing infections, having a significant share of the population vaccinated will help to keep case counts from surging out of control, experts predict. Unvaccinated individuals are roughly six times as likely to test positive for COVID as their vaccinated peers. Whats more, people who arevaccinatedand do contract COVID are less likely to spread it to others, studies show.

Last November, the U.S. was seeing about 160,000 new infections each day; now, were counting about 80,000, which is still very high, but you're not seeing that exponential growth that we saw last year, Madad said.

Last year, everybody was at risk, said Catherine Troisi, an infectious disease epidemiologist with the University of Texas Health School of Public Health. This year, you can protect yourself.

Another factor that could make this winter less lethal than last: advancements in the treatment of COVID-19.

Two drugmakers, Merck and Pfizer, have requested emergency use authorization from the U.S. Food and Drug Administration (FDA) for antiviral pills that they say can greatly reduce the risk of hospitalization and death in people who are infected with the virus.

If authorized, the pills will be the first at-home treatment designed to keep the disease from progressing. Currentlyavailable treatmentsmust be administered in a health care facility.

If you have COVID-19 and especially if you have aweakened immune systemor are otherwise at risk these are a game-changer, Dowdy said. However, when it comes to preventing an infection in the first place, vaccines are far and away our best tool and will remain that way, he added.

The coronavirus will still have some advantages this winter. Cold weather pushes people indoors, where germs, including the one that causes COVID-19, spread more easily. Some states in the Northeast, even those with high vaccination rates, are already seeing a spike in COVID cases, Troisi pointed out.

Add to that the fact that virus transmission, driven mostly by the extremely contagiousdelta variant, is still high throughout most of the U.S., which means there's more chances of you coming in contact with the virus and being exposed to it, Madad said. Plus with the holidays on the horizon, more people will take to the rails, roads and skies to visit friends and family, giving the virus even more opportunities to circulate.

If you're unvaccinated, you should worry, Madad said, pointing to the relentless delta variant, which sent cases soaring this summer. The data and the science are clear: You are at really high risk for getting exposed to the virus and potentially having severe outcomes.

If youre fully vaccinated, the sky is not falling down; you're still well protected, she added. However, abooster shot, if you are eligible, can add even more protection. So can wearing a mask in indoor public settings.

The bottom line is, cases are increasing and it's a time to continue to be vigilant, Madad said.

When will all these COVID crests flatten out for good? Thats a little harder to predict, the experts say, and the virus has surprised us again and again, most recently with the emergence of the omicron variant. But the pandemic as we know it will likely shift when we gain more control over the outbreak, said Anthony Fauci, M.D., the nations top infectious disease expert, in a recent news briefing.

We dont know really what that number is, but we will know it when we get there, he said. It certainly is far, far lower than 80,000 new infections per day, and its far, far lower than 1,000 deaths per day and tens of thousands of hospitalizations.

In the meantime, seasonal waves will likely persist, Dowdy said, adding that we could see them for many years, if not for our lifetimes. But as we build up immunity to the virus, COVID will likely get milder over time, he said, which is why getting vaccines into the arms of as many people as possible is so important.

The world may never look like it did before the pandemic, and we may still be in for a winter surge in cases this year. But from a COVID-19 perspective, there are many reasons to believe that things will be much better in 2022 than they have been for us these past two years, Dowdy said.

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Is a Fifth Wave of COVID-19 on the Horizon? - AARP

People waiting to receive a Covid-19 vaccine in Marseille. The new potentially more contagious omicron variant of the coronavirus was detected in mainland France on Thursday.Credit...Daniel Cole/Associated Press

The French authorities confirmed the first cases of the Omicron version of the coronavirus in mainland France on Thursday, but their alarm remained focused on a surge of infections fueled by the Delta variant.

France reported nearly 50,000 new cases of the virus in 24 hours on Wednesday, the highest daily total since the spring. The number of reported cases per 100,000 people has soared from less than 100 to more than 300 over the past month.

We need to anticipate there are still a lot of uncertainties, Jean-Franois Delfraissy, the head of the French governments Covid-19 scientific advisory council, told BFMTV on Thursday, referring to Omicron. But lets not fight the wrong fight. The real fight, the real enemy, is the fifth wave with the Delta variant.

The surge has alarmed French authorities, even though they have so far ruled out a return to lockdowns or business closures. Mr. Delfraissy said that cold had pushed people indoors and that social distancing was no longer being scrupulously followed. The average number of new hospital admissions, including in intensive care, has also increased by roughly 40 percent over the past weeks, according to official statistics.

But hospitalizations are still below the peaks seen in previous waves, thanks to a vaccination rate of 75 percent of the entire population, and Mr. Delfraissy said that if people exercised renewed vigilance by avoiding gatherings, working from home when possible and wearing masks more often France could be spared the worst outcomes.

Christmas isnt in danger if we are all careful, he said.

Source: Center for Systems Science and Engineering (CSSE) at Johns Hopkins University. The daily average is calculated with data that was reported in the last seven days.

The French government, which recently made all adults eligible for booster shots, has steered clear of mandating vaccines, arguing that coercion would be counterproductive. Olivier Vran, the health minister, told reporters this week that a more powerful incentive was the national health pass, which is required to access museums, restaurants, cinemas and other public venues.

The announcement of two Omicron cases on Thursday in mainland France has added to concerns, even though scientists are still trying to understand the threat posed by the variant.

The health authority for the le-de-France region, which includes Paris, said that the Omicron variant had been found in a man in his 50s, who returned from Nigeria last week and tested positive for Covid-19 after disembarking from his flight, though he showed no symptoms. The man, who was not vaccinated, was isolating at home, officials said.

In eastern France, health authorities in the Grand-Est region said in a statement that Omicron had been detected in a woman in her 40s who returned from South Africa last week. The woman was vaccinated but experiencing symptoms, and has been isolating at home.

Previously, France had confirmed only one case of the Omicron variant, in the overseas department of Runion, in the Indian Ocean.

Uncertainty over how dangerous Omicron really is had prompted the French authorities to halt flights with 10 countries in southern Africa, where the variant was first detected. Flights will be allowed to resume starting this weekend, but with some restrictions on travelers still in place. France will also require all visitors arriving from outside the European Union to provide a negative coronavirus test result, regardless of their vaccination status.

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New York Reports Five Omicron Cases - The New York Times

Scientists at Pfizer's research and development laboratories in Groton, Conn., worked on the COVID-19 pill called Paxlovid. Stew Milne/AP hide caption

Scientists at Pfizer's research and development laboratories in Groton, Conn., worked on the COVID-19 pill called Paxlovid.

Two new drugs are awaiting authorization from the Food and Drug Administration for treating patients with COVID-19, and both may be effective against the omicron variant.

One is made by Merck, the other by Pfizer.

The Merck drug has been in development for years. When the pandemic began, Pfizer's drug didn't exist. The story of its development is another example of how COVID-19 has sped up the drug and vaccine development process.

Pfizer wasn't starting exactly from zero. Mikael Dolsten, Pfizer's chief scientific officer, says that during the SARS outbreak in 2003, company scientists had begun to search for ways to combat that coronavirus.

In particular, they looked for proteins crucial for the virus to replicate once it infected someone.

One viral protein they focused on is called a protease. "We have learned that protease is a key regulator for the virus to unleash its machinery and hijack the human cells," Dolsten says.

Pfizer scientists thought if they could find a compound that would disrupt the protease, it would essentially stop the virus dead in its tracks.

That search petered out when the 2003 SARS outbreak passed. No disease, no market for a drug.

But Dolsten says the knowledge that was gained convinced them that a protease inhibitor would work to corral the coronavirus causing COVID-19.

They made computer models of the viral protease protein and assembled drug candidates that might block it.

"We actually had to design and synthesize some 600 unique chemical compounds," he says.

That was just the start. They had to test each compound to see how well it prevented the virus from infecting cells in the lab. Then they had to determine whether it would do the same thing in animals infected with the coronavirus. They also needed to find a candidate that would remain in someone's body long enough to have the desired antiviral effect. And they wanted to do all this fast.

"We put in place some very aggressive timelines where we made all of this happen over four months to come down to the optimal medicine," Dolsten says.

In the end, the drug developers had a candidate they thought would work. They mixed it in a pill with an old drug called ritonavir that extended the action of the protease inhibitor.

This past July, Pfizer began a study of people infected with the coronavirus who were at high risk of developing severe COVID-19. Half got the drug, called Paxlovid, within three to five days of the onset of symptoms, half a placebo.

Dolsten says the study was halted early because the drug appeared to be working. He says there was nearly a 90% reduction in hospitalization among people taking the new drug, "And 100% protection against death."

A similar analysis for the Merck drug found it lowered the risk of hospitalization or death by 50%. In a subsequent analysis presented to the FDA, the risk reduction fell to 30%, however.

One good thing about these drugs is that because they're pills, they can be taken at home, unlike some current therapies that require an infusion.

Because Pfizer's pill isn't affected by changes in the spike protein, Dolsten says he expects the new drug will work equally well against any variant of the coronavirus, including omicron.

Although Pfizer has not yet published details of its study, researchers seem impressed.

"I think this drug along with the drug from Merck are both very promising antivirals that, as we had predicted early in this pandemic, work when given early in the infectious course," says Stanley Perlman, a microbiologist at the University of Iowa, where he's been working on coronaviruses for decades.

Perlman adds that the key to preventing damage from a coronavirus infection is to stop it from replicating and spreading throughout someone's body.

Protease isn't the only viral protein that might lead to a viable treatment.

"I think there's several other targets in how the virus reproduces," Perlman says. "But the most important thing to think about for all of them is they almost all have to be given very early after infection to really have a role in helping prevent people from progressing to more severe disease."

And since it looks like we'll be living with COVID-19 for a while, drugmakers have an incentive to develop other kinds of drugs to treat the disease.

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Pfizer COVID pill benefited from research on SARS : Shots - Health News - NPR

The Minnesota patient, who has recovered, fell ill on Nov. 22, suggesting that the variant already had begun to circulate even before South African health authorities first announced its detection there.

This case, you know, was getting ill even before we were hearing about Omicron from South Africa, Kris Ehresmann, infectious disease director for the Minnesota Department of Health, told reporters on Thursday.

Omicron carries more than 50 genetic mutations that in theory may make it both more contagious and less vulnerable to the bodys immune defenses than previous variants. Available vaccines may still offer substantial protection against severe illness and death following infection with the variant, but much remains unknown.

Most of the mutations are on the viruss spike protein, which the existing vaccines target. Federal officials are asking vaccinated people to get booster shots and the makers of the two most effective vaccines, Pfizer-BioNTech and Moderna, are preparing to reformulate their shots, if needed.

But it remains unclear whether Omicron will change the anti-coronavirus playbook. If the new variant turns out to be more transmissible than, say, the Delta variant, officials said, health guidance may stiffen more vigilance about masking indoors, sterner requirements for boosters.

Its worth re-asking the question, Ive started to get a little less careful than I was is that the right thing? said Dr. Bob Wachter, a professor and chair of the department of medicine at University of California, San Francisco. If, psychologically, you need a month to get prepared to move backwards, you should get ready for the possibility.

Dec. 3, 2021, 3:07 p.m. ET

That could be tough. The options government officials have to control the spread of the virus have proved to be politically limited in this country, even where communities have been open to restrictions. Californias health measures saved countless lives, for instance, but also helped fuel a recall effort against Gov. Gavin Newsom this year.

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San Francisco Followed Covid Rules. Will Omicron Change the Playbook? - The New York Times

The total number of recorded COVID-19 deaths has passed 5 million globally, with over 750,000 deaths in the United States alone. However, these figures are unlikely to reveal the true impact of COVID-19 on the population.

Scientists have now shown an increased risk of death among COVID-19 survivors 12 months after the infection.

For people younger than 65 who were hospitalized with COVID-19, the risk of death in the 12 months after the infection was 233% higher than it was for people who did not have the disease, results published in the journal Frontiers in Medicine have shown.

Nearly 80% of all deaths of people in the study who had recovered from COVID-19 in the past 12 months were not due to cardiovascular or respiratory causes, suggesting that the impact of the virus is significant and wide-ranging, even after the initial infection has been fought off.

Prof. Arch Mainous, an author of the paper, told Medical News Today in an email: A lot of interest in the scientific community has focused on what happens to patients after having an episode with COVID-19. Some people are focusing on long COVID or persistent symptoms like brain fog or lack of smell. We were interested in the hard outcome of death after COVID-19 recovery.

We thought that the impact of COVID-19 would be significant enough to engender complications. The overall trauma or psychological insult to the body would be dramatic enough to create lasting damage.

To measure the impact of COVID-19 on long-term health, researchers from the University of Florida looked at electronic healthcare records from patients tested for COVID-19 in any setting in the University of Florida health system, both in Gainesville and Jacksonville. People who died within 30 days of their COVID-19 tests were excluded from the analysis.

Out of 13,638 people tested for COVID-19 between January 1 and June 30, 2020, 424 people were found to have COVID-19. Of this number, 178 people were classified as having severe disease. The rest were negative for SARS-CoV-2, the virus that causes COVID-19, as determined by polymerase chain reaction (PCR) testing.

The researchers then evaluated the electronic healthcare records of these people, following them for 365 days after the first PCR test. They found that 2,686 people in the cohort had died.

The team then analyzed the healthcare records to determine cause of death and compared the risk of death for people who had had COVID-19 with that of people who had not tested positive for SARS-CoV-2.

They found that the vast majority of deaths among people who had had COVID-19, nearly 4 out of 5 of these deaths, were not due to cardiovascular or respiratory illness, despite much existing research into the impact of COVID-19 on these systems.

Prof. Mainous said, Treatment in the hospital is [fine for surviving] the initial episode, but our strategy should focus on keeping people out of the hospital in the first place.

Taking your chances that you might get COVID-19 but that it will be mild, or that you will just rely on treatments to pull you through a severe episode is a course of action with big risks.

These figures demonstrate that the impact of COVID-19 could last longer than we had originally anticipated. However, they do not tell us why.

Prof. Mainous continued, Although there are a variety of theories floating around about why there are post-acute complications from COVID-19, and more work needs to be done to establish definitively the mechanism, it seems likely that the intense level of inflammation in the body affects multiple parts of the body.

Children were not included in this study, but Sammie Mcfarland, founder and CEO of Long Covid Kids, told MNT in an interview that the study shed some light on a topic that should get more attention and that we still do not understand the long-term impact of COVID-19 on children.

In the United Kingdom, she said, We dont know if the children coming out of hospital go on to recover, go on to die, or go on to get long COVID, we just dont know.

She also pointed out that while cases of pediatric multisystem inflammatory syndrome, a rare complication that can occur in children with COVID-19, have been recorded, we do not know what has happened to many of these kids.

Mcfarland told us: Those children are living now with some severe impairment, and some of them have died. And those children arent recorded as COVID deaths. And theyre not recorded in the COVID data. But its still from COVID.

For live updates on the latest developments regarding the novel coronavirus and COVID-19, click here.

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COVID-19 survivors have higher risk of death 12 months after infection - Medical News Today

Pedestrians wearing face masks against the coronavirus walk along Regent Street in London, Tuesday, Nov. 30, 2021. The emergence of the new COVID-19 omicron variant and the worlds desperate and likely futile attempts to keep it at bay are reminders of what scientists have warned for months: The coronavirus will thrive as long as vast parts of the world lack vaccines.

Rice University researchers have been leading a project, funded by the U.S. Centers for Disease Control and Prevention, of mapping out mutations of the coronavirus. Most recently, they've been focusing their efforts on the omicron variant, which was classified as a variant of concern by the World Health Organization last week.

The first cases of the variant in the United States were identified this week.

Gene Godbold, a scientist with Austin-based contractor Signature Science who has compiled a list of omicron's mutations, spoke with Houston Public Media about what the research says about the new variant.

Listen or read the interview below, edited for length and clarity.

Looking at the mutations of this variant, do any of them raise alarm bells? And are any associated with higher risk of transmission or the ability to evade the protection we get from vaccines?

Thats a deep kind of question. Its not just one thing. So theres almost 1,300 residues in the spike protein. And a lot of them, if they change to something else, might not have any effect at all. But compared to the Wuhan strain, the ancestral string, this has got like 30 amino acid changes and then a couple of deletions and insertions in areas that youd want to care about.

OK, so we can break it down. We can talk about transmission first.

Theres good reason to believe that the mutations make this more transmissible. Before delta, alpha was the most transmissible variant. And (omicrons) got the same mutations as alpha does, plus its got some other concerning ones.

Obviously, the reason were talking about is because we know its already spreading. The proof is in the pudding already. So we know that the virus is a problem, and it seems to be spreading in the face of all the other variants.

Given the mutations that the science community knows and understands already, is it possible that this variant could evade protection the vaccines give to us?

Basically, the takeaway message is that the omicron variant has more immune evasive mutations than anything weve seen yet. And it may have even more than that because its got new ones that nobody studied yet. So the question of whether it evades the vaccines? It probably doesnt. I mean, it probably isnt going to evade a normal person with a normal immune system. And why is this? Like a normal immune response, you can generate dozens of different types of neutralizing antibodies. I think the most immune invasive variant so far has knocked out like six of those neutralizing antibodies.

I cant guarantee it, but it looks like Omicron is going to wipe out a lot more than six. That doesnt mean that you dont have any defense, because obviously neutralizing antibodies arent the whole thing, but neutralizing antibodies are really important to prevent transmission and colonization. So its probably going to be more likely to get a foothold into people, is what Im betting on. Even people who are vaccinated and boosted are probably still gonna be able to get this more than the other variants.

Now, theres no way to tell how this is going to work out in terms of what kind of sickness they get. It may be mild, it may be just a cold for the people that are vaccinated. Were going to have to see how that works.

You mentioned the possibility of more breakthrough infections for people that are vaccinated. And you kind of touched on people with normal immune systems. Do you have any sense in how this might play out in someone who is immunocompromised?

Theres a variety of ways a person can be immunocompromised. Actually there's like five ways that you could be compromised. Each one is going to be different, so it would be hard to generalize about something like that. But in general, it would not be good. I mean, that this is like common sense, but basically, if you're immunocompromised, you want to avoid going out. Sorry, thats lame, but that's true.

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Omicron could be tougher against the COVID-19 vaccine than other variants, Rice research shows - Houston Public Media

New COVID variant hits US, 'omicron' strain found in California

The Centers for Disease Control and Prevention confirms the coronavirus variant omicron is present in California.

STAFF VIDEO, USA TODAY

At a Friday news conference, Dr. Anthony Fauci urged Americans to get their COVID-19 vaccine booster shots, saying the booster dose increases "the number of neutralizing antibodies against all the variants."

While there are many unanswered questions about omicronhealth officials will know more about the transmission and severity of the variant in the next few weeks, said Fauci, President Joe Bidens chief medical adviser.

Meanwhile,"CDC is providing support to enhance and streamline genomic sequencing nationally, and is expanding surveillance of international travelers," said Centers for Disease Control and Prevention Director Dr. Rochelle Walensky.

But while the world is focused on omicron, Walensky said"we should remember that 99.9% of cases in the country right now are from delta." She added that measures used to counter the delta variant, including vaccinations, mask wearing, social distancing and increased testing, will also be effective in curbing the spread of the omicron variant.

"Our recommendations for protecting against COVID remain the same regardless of the variant," she said.

World Health Organization officials echoed this sentiment ata Friday news conference from the Philippines.

"The positive news in all of this is that none of the information we have currently about omicron suggests we need to change the directions of our response," saidDr. Takeshi Kasai, WHO regional director for the Western Pacific.

"But every country and every community must prepare for new surges in cases, Kasai added.

What are omicron variant symptoms?Everything to know about the latest coronavirus strain

Understanding omicron: How the latest coronavirus variant, now in the US, is mutating and spreading

Also in the news:

As the emergence of omicron raises concerns over the Beijing Winter Olympic Games in February,Zhao Weidong, spokesperson for the organizing committee, told reporters at a Friday news conferencethatOlympic participants will live and compete in a bubblewhileonly Chinese residents who have been both vaccinated and tested will be allowed at venues.

Oklahoma'sattorney generalsuedthe Biden administration Thursday over a requirement that all National Guardmembers receive a COVID-19 vaccine.

Los Angeles Lakers star LeBron James has been cleared from the NBAs healthy and safety protocols and will be available to play in Fridays game against the Los Angeles Clippers, the league announced.

Workers covered by existing COVID-19 vaccine mandates in New Mexico will be required to get booster shots as well, beginning in January.The state Department of Healthamended its public health order requiring workers at schools, hospitals and congregate care facilities and the governor's office to be vaccinated, adding the additional dose to existing requirements.

Today's numbers:The U.S. has recorded more than 48 million confirmed COVID-19 cases and more than 785,000deaths,accordingtoJohns Hopkins Universitydata. Global totals: More than 264 million cases and 5.2 million deaths. More than 197 million Americansroughly 59.6% of the populationare fully vaccinated,according to theCDC.

What we're reading:The threat of omicron is underscoring the importance of vaccination and boosters against COVID-19, especially for people of color who have disproportionately suffered during the pandemic.

Keep refreshing this page for the latest news. Want more?Sign up forUSA TODAY's Coronavirus Watch free newsletterto receive updates directly to your inboxandjoin ourFacebook group.

The first known case of the omicronvariant was detected in the U.S. on Wednesday, in San Francisco, California. Since then, the heavily mutated variant has been identified in at least five other U.S. states.

By Thursday, another omicron case was confirmed in California in a Los Angeles County resident who likely contracted the virus during a trip to South Africa last month, according to the county's public health department. At least five people in the New York City metropolitan area were infected with the omicron variant, New York Gov. Kathy Hochul said at a Thursday news conference.

A man from Minnesota who had attended an anime convention in Manhattan in late November was also infected with the variant, she added.

"Let me be clear: This is not cause for alarm. We knew this variant was coming and we have the tools to stop the spread,''Hochul said on Twitter.

"Get your vaccine. Get your booster. Wear your mask.''

Officials reported another case in a Colorado woman who had recently traveled to southern Africa. The variant was also confirmed in an unvaccinated Hawaii resident with no recent travel history, state health officials said.

Friday, Nebraska health officials confirmedsix people tested positive for the omicron variant. One of the individuals likely contracted the virus while traveling to Nigeria, and the other five were in the same household as the first case, officials said. Only one of them was vaccinated.

Global vaccine equity: Omicron isn't a surprise to advocates who have fought for global vaccine equity

South Africa has seen a "steep rise in infections" in the past seven days,South African Health Minister Joe Phaahla said at a Friday news conference, adding that theover 2,500 new cases last Thursday when the omicron variant was first detected has jumped to over 11,500 this Thursday. All districts are seeing increases in cases with rapid increases and hospitalizations in Gauteng, a province innortheastern South Africa.

"While we are still dealing with few days and limited data, indications are that this variant is indeed highly transmissible,"Phaahla said.

While there have been infections of vaccinated people, Phaahla said most of these cases have only led to mild illness and the majority of hospitalizations have been among unvaccinated young people below age 40. The country is also seeing increased hospital admissions of children under age 4, highlighting the need to include pediatric beds and staff in preparations for surging cases.

The omicron variant has also been spreading to older age groups, saidDr. Michelle Groome from the National Institute for Communicable Diseases. She added that early evidence indicates this variant is more transmissible than others and that there is a "degree of immune escape," meaning the variant'sability to resist an immune response from prior infections or from vaccines.

US COVID-19 map: Tracking cases and deaths

Both chambers of Congress passed a billThursday to fund the government through Feb. 18, narrowlyavoiding a government shutdownbefore a Friday deadline.

A group of Republican senators nearly forced a shutdown after they threatened to delay passage of the bill in the upper chamber. Theywanted languagepreventingthe use of federal money to carry out a Biden administration mandate on workplace vaccinations, but the amendment to do that failed 48-50.

Kansas Republican Sen. Roger Marshall, who introduced the amendment along with Sen. Mike Lee, R-Utah, said the president's order will displace a significant number of workers.

"This is about jobs in Kansas. It's about jobs in Texas, in Utah, across the nation," he told reporters on Capitol Hill before the vote. "An unconstitutional federal vaccine mandate'sgoing to lead to an economic shutdown, jobs lost back home."

Biden announced last montha policythat large businesses those with 100 or more employees require workers to be vaccinated against COVID-19or be regularly tested.Noncompliant businesses couldfacepenalties of nearly $14,000 per violation. Therequirement is currently on hold due to several lawsuits.

"I am glad that in the end cooler heads prevailed," SenateMajority Leader Chuck Schumersaid of thevote to keep the government open. "The government will stay open."

New York Gov. Kathy Hochul urgedthe 53,000 people who attended a November anime convention in New York City to get tested for COVID-19 immediately after an attendee from Minnesota tested positive for the omicron variant. She said health officials will be in contact with attendees.

"This is not cause for alarm," she said at a Thursday news conference."It was foreseen ever since it was first reported out of South Africa, that we knew it would come to New York State at some point."

Anime NYC, which required vaccinations and masks for the conference, according to its website, confirmed on Twitter that one of its attendees tested positive and said organizers are working with health agencies to email and call attendees to notify them of the confirmed case.

"You are strongly advised to get tested," the organization said, adding that the attendee was vaccinated and developed mild symptoms.

Study: Patients have greater risk of death after recovery from severe COVID-19

Patients who have recovered from severe COVID-19 have more than three times the mortality risk within the year following their illness than people who have not contracted the virus, according to a recent study by University of Florida researchers.

An earlier study by UF researchers,published in the journal Frontiers in Medicine, foundpatients who had a severe case of the disease were more than twice as likely to need rehospitalization for COVID-19 complications, which underscores the serious effects the virus can have on the body.

The risk for those younger than 65 who had severe cases is higher than for those older than 65. But patients who had mild or moderate COVID-19 were not found to be at increased risk of death compared to those who did not contract the disease.

These findings reinforce that the internal trauma of being sick enough to be hospitalized with COVID-19 has a big consequence for peoples health. This is a huge complication of COVID-19 that has not been shown before, saidArch G. Mainous III,the studys lead investigator.

Jill Pease, UF Health

Contributing: The Associated Press

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CDC director says recommendations for protection the same, 'regardless of the variant': COVID updates - USA TODAY

SIOUX FALLS, S.D. (KELO) There were 512 new total COVID-19 cases reported on Friday, bringing the states total case count to 168,271, up from Thursday (167,759).

While the difference in the total case count reported Friday and Thursday equals 512, when you add the PCR, or newly confirmed, cases (395) and antigen, or new probable, cases (118), there were 513 new cases.

The number of active cases reported on Friday is at 7,572, up from Thursday (7,416).

There were two new deaths reported, bringing the total to 2,357. The two new deaths reported were two men in the 50-59 and 70-79 age range from Brown and Brule Counties.

Current hospitalizations are at 247, down from Thursday (248). Total hospitalizations are at 8,523, up from Thursday (8,490).

Total recovered cases are now at 158,342, up from Thursday (157,988).

The DOH currently reports total tests each day. There have been 1,726,609 total tests reported as of Friday, up 5,463 from 1,721,146 total tests reported on Thursday.

The latest seven-day PCR test positivity rate for the state is 16.4% for Nov. 25 Dec. 1.

Of South Dakotas 66 counties, 60 are listed as having high or substantial community spread. High community spread is 100 cases or greater per 100,000 or a 10% or greater PCR test positivity rate.

There have been 1,084 Delta variant cases (B.1.617.2, AY.1-AY.25) detected in South Dakota through sentinel monitoring.

There have been 176 cases of the B.1.1.7 (Alpha variant), 3 cases of P.1. (Gamma variant) and 2 cases of the B.1.351 (Beta variant).

The DOH announced changes to how it reports vaccinations on the COVID-19 dashboard as of Monday, October 14. It now includes a breakout of how many people have received booster doses. Due to data clean-up efforts, the percentages of people whove received one dose or completed the series have changed. Findthe DOH explanation in this story.

On Wednesday, November 24, the South Dakota Department of Health updated how it reports the percent of the population getting vaccinated. To align with the vaccine-eligible population, the Department of Health is including children who are 5-11 years old. The state says there was a decrease of 7% from the 12+ year old population.

As of Friday, 65.06% the population 5-years-old and above has received at least one dose while 53.89% have completed the vaccination series. 16.39% of those eligible have completed their booster dose.

There have been 570,909 doses of the Pfizer vaccine administered, 410,946 of the Moderna vaccine and 33,992 doses of the Janssen vaccine.

There have been 167,433 persons who have completed two doses of Moderna. There have been 232,241 persons who have received two doses of Pfizer.

As for booster doses, 71,617 people have received a 3rd Pfizer shot, 54,818 have received a 3rd Moderna dose and 1,475 have received a Janssen booster.

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COVID-19 in South Dakota: 512 total new cases; Death toll rises to 2,357; Active cases at 7,572 - KELOLAND.com

COLUMBUS, Ohio (WCMH) The Ohio Department of Health releasedthe latest number of COVID-19 casesin the state.

As of Thursday, Dec. 2, ODH reports a total of 1,708,292 (+9,131) cases, leading to 87,244 (+366) hospitalizations and 10,848 (+41) admissions into the ICU. The state reported Thursday 58.02% of the states population 6,782,133 Ohioans have started the COVID-19 vaccination process, an increase of 10,935 from the previous day.

ODH reported 104 deaths Tuesday, bringing the total to 26,587. The state is updating the number only after death certificates have been processed, usually twice a week.

The 21-day case average now sits at more than 5,500.

ODH director Dr. Bruce Vanderhoff and other Ohio health leaders gave an update on the current uptick of COVID-19 cases and hospitalizations. While Delta variant is still the primary COVID-19 variant in Ohio, Dr. Vanderhoff did discuss the new Omicron variant.

If the Omicron variant shows up in Ohio, well likely see it reasonably quickly in our states genetic sequencing data. said Dr. Vanderhoff. Much remains unknown at this point including whether its more transmissible or capable of causing more serious illness.

The first U.S. case of the Omicron variant was reported Wednesday in California.

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Coronavirus in Ohio Thursday update: Over 9,000 new cases - NBC4 WCMH-TV

(WJW) Theres sobering news as COVID-19 cases continue to rise.

The highest concentration of people in the hospital with COVID-19, across the state, is right here in Northeast Ohio.

The last time more Ohioans were treated in the hospital for COVID-19 was all the way back on January 12, when 4,000 patients were hospitalized across the state, said Ohio Department of Health director Dr. Bruce Vanderhoff.

The director says the majority of the people in the hospital, including the ICU, are people who are unvaccinated.

While someone whos fully vaccinated may, in some instances, still catch COVID-19, they are far more likely to be able to weather that case at home, rather than ending up in a hospital or on a ventilator or in the obituary pages, said Dr. Vanderhoff during a Thursday afternoon virtual news conference.

Overall, were approaching the highest number of COVID patients that weve treated across the health system throughout the whole pandemic, said Dr. Dan Simon, president of academic and external affairs and chief scientific officer at University Hospitals.

He says the hospitals in the system are at more than 95% capacity, filled with both COVID and non-COVID related patients.

About 20% of intensive care unit patients across the health system now have COVID and in some of our community medical centers, 50% of the patients in the hospital have COVID, said Dr. Simon.

He says the prolonged pandemic and recent surge is putting a strain on staff. Some are simply stressed out, while others are dealing with COVID themselves and that sometimes means fewer people to care for patients.

Dr. Simon says more than 90% of patients being treated in the ICU at UH are unvaccinated.

We are seeing an increased number of vaccinated individuals with breakthrough who are being admitted to the regular floors with mild to moderate disease. These typically are individuals who are high-risk over 65, heart disease, lung disease, cancer or immuno-suppressed, Dr. Simon said.

Dr. Simon says the positive test rate a UH this week has been 17%, but despite shrinking hospital capacity, they have a plan if things get worse.

To allow us to go from 1,700 beds across the health system, to over 5,100, he said.

He believes after Thanksgiving travel and holiday gatherings, the number of COVID cases will probably go up.

We dont peak here for another two weeks plus, so the worst is yet to come, said Dr. Simon.

Ohio lags way behind much of the country in vaccinations with only 58% of Ohioans who have gotten the shot.

Dr. Simon says he believes part of the latest surge is because its getting cold and people are spending more time indoors.

Health experts still urge people to get vaccinated. If youre already vaccinated, get a booster and continue to wear masks and social distance if youre in large congregant settings, especially with people you dont know.

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Northeast Ohio sees highest COVID hospitalization levels in the state - fox8.com