Category: Corona Virus

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US COVID-19 cases and deaths by state | USAFacts

April 24, 2023

Total Reported7-Day Average (Apr 02)Cases98,924,89911,581Deaths1,097,474139

1 Month3 Month6 MonthAll time

In the United States, there were 0 newly reported COVID-19 cases and 0 newly reported COVID-19 deaths on Apr 02, 2023

From cities to rural towns, stay informed on where COVID-19 is spreading to understand how it could affect families, commerce, and travel. Follow new cases found each day and the number of cases and deaths in the US. The county-level tracker makes it easy to follow COVID-19 cases on a granular level, as does the ability to break down infections per 100,000 people. This county visualization is unique to USAFacts and will be updated with the most recent data as frequently as possible. The underlying data is available for download below the US county map and has helped government agencies like Centers for Disease Control and Prevention in its nationwide efforts.

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US COVID-19 cases and deaths by state | USAFacts

Coronaviruses | NIH: National Institute of Allergy and …

April 24, 2023

Coronaviruses are a large family of viruses that usually cause mild to moderate upper-respiratory tract illnesses in humans. However, three coronaviruses have caused more serious and fatal disease in people: SARS coronavirus (SARS-CoV), which emerged in November 2002 and causes severe acute respiratory syndrome (SARS); MERS coronavirus (MERS-CoV), which emerged in 2012 and causes Middle East respiratory syndrome (MERS); and SARS-CoV-2, which emerged in 2019 and causes coronavirus disease 2019 (COVID-19).

Building on previous research on SARS and MERS, NIAID scientists and NIAID-supported researchers mobilized quickly to develop COVID-19 therapeutics, vaccines and diagnostics. Researchers continue to conduct basic research to understand how coronaviruses infect cells and causes disease, and what interventions can detect, prevent and stop the spread of disease.

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Coronaviruses | NIH: National Institute of Allergy and ...

U.S. Authorizes a New Round of Covid Boosters

April 22, 2023

In a nod to the ongoing risk the coronavirus poses to millions of Americans, the Centers for Disease Control and Prevention recommended on Wednesday that adults 65 and older and those with weakened immune systems receive another dose of the reformulated booster that debuted last fall.

The endorsement followed a daylong discussion by the C.D.C.s expert advisers. The Food and Drug Administration authorized the booster plan on Tuesday, and the C.D.C.s recommendation was the final administrative step. Eligible Americans will be able to receive booster doses immediately.

Federal health officials are also phasing out the original vaccine formulas created by Pfizer-BioNTech and Moderna, revoking their authorizations in the United States. And instead of needing an initial series of two shots, unvaccinated people will now require just a single dose of the reformulated, or bivalent, Covid shot to be considered vaccinated.

Until now, federal officials had required two doses of the older vaccine before recipients could begin to receive the bivalent boosters, a process some experts felt was confusing.

Limited data on the reformulated vaccines indicate that in older adults, the shots offer additional protection against severe disease and death from Covid, although the protection wanes rapidly in the weeks after inoculation.

There are about 53 million adults 65 and older in the United States, accounting for about 16 percent of the population, according to the Census Bureau. And seven million Americans have weak immune systems because of an illness or a medication.

Roughly 250 people in the United States are still dying from Covid-related causes each day, a vast majority of whom are over 70 or have impaired immune systems. The median age of those hospitalized is 75, according to the C.D.C. Yet only about 43 percent of adults 65 and older have received a bivalent booster shot so far.

By this point, most Americans have built up some immunity against the virus, whether through prior infections, vaccinations or both. The new guidelines acknowledge as much, but allow for those still at high risk from the virus to protect themselves, and to do so free of charge.

The one-size-fits-all policy was simple but not optimal, said Dr. Jeremy Faust, an emergency medicine physician and health policy expert at Brigham and Womens Hospital in Boston. The new regimen acknowledges that theres now an extraordinary spectrum of Covid risk, from mild to massive, depending on who you are.

People who are severely immunocompromised, such as organ transplant recipients, may want to opt for booster shots every six months or even more frequently, Dr. Faust said.

The new guidelines come weeks after Britain and Canada recommended additional shots for older adults and immunocompromised people, among others.

The C.D.C. now says that adults 65 and older may opt for another dose of the bivalent vaccine at least four months after their first shot. Those with weakened immune systems may do so two months after their previous bivalent dose, and may choose to receive more doses in consultation with their health care provider.

In the meeting of C.D.C. advisers on Wednesday, Dr. Camille Kotton, a physician at Massachusetts General Hospital, noted that the new recommendations did not include immunocompromised children 6 months through 4 years of age. That leaves those medically frail children including recipients of organ transplants unprotected against the virus, she said.

As a mom and doctor, this seems like we are leaving them so vulnerable, she said in an interview.

For most Americans, the F.D.A. plans to encourage annual Covid shots in the fall, much as it does with flu shots. Health officials will decide on the exact composition of the shot in June, based on the version of the virus circulating at the time.

The bivalent vaccine targets the original variant of the coronavirus as well as variants BA.4 and BA.5, which were dominant last summer. But BA.4 and BA.5 were quickly supplanted by newer versions.

The most recent Omicron subvariant, XBB.1.5, now accounts for about 78 percent of cases in the United States, and another version, XBB.1.6, for about 7 percent. So far, the reformulated vaccines seem to prevent severe illness and hospitalization after infection with these variants.

Federal health officials also are making changes to the process for those receiving the initial shots.

Unvaccinated people will receive a single dose of the bivalent vaccine, rather than multiple doses of the original monovalent vaccine. The rationale is that most unvaccinated Americans now presumably have some measure of immunity from a prior infection and may not need two doses at the beginning, the F.D.A. said.

Some experts were sharply critical of the advice. Reams of data suggest that the vaccines are most protective when given in two doses and followed by one or more boosters to reinforce the shield, said John Moore, a virologist at Weill Cornell Medical College.

F.D.A. has consistently over-interpreted the performance of the bivalent formulation when given as a booster, Dr. Moore said. Now it seems to have gone beyond the science and decided it has some kind of magic power as a first dose.

It may be reasonable to assume that nearly all unvaccinated adults have already been infected at least once and can get by with just a single dose, said Deepta Bhattacharya, an immunologist at the University of Arizona.

I guess the F.D.A. is just trying to simplify given the reality on the ground, he said. But immunologically, youd want to get two shots if its your first exposure.

The agency could instead recommend two doses of a bivalent vaccine and say that those who know of a prior infection can elect to forego the second dose, Dr. Bhattacharya said. But, he added, in reality, I doubt a clause like that would make much practical difference.

The F.D.A. said it had carefully reviewed the available epidemiologic evidence, scientific publications and data provided by sponsors indicating that a single bivalent vaccine dose provided to individuals previously infected with Covid-19 provides an immune response equal to, or superior to, two doses of the original vaccine.

The agency believes that this approach will help encourage future vaccination, particularly among those who have not chosen to be vaccinated to date, the F.D.A. said in its statement.

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U.S. Authorizes a New Round of Covid Boosters

New COVID subvariant Arcturus reported in Mass. with new symptom

April 22, 2023

Just as emergency orders are being lifted and testing sites close, a new omicron subvariant of COVID-19 has the World Health Organizations attention as it spreads in India and the United States, including Massachusetts.

XBB. 1.16, also called Arcturus, was first detected by the WHO on Jan. 23 before designating it as a new variant under monitoring on March 22.

This designation is less serious than a variant of interest or variant of concern, but the WHO said there are early signals that Arcturus is dominating over other subvariants, including XBB 1.15, or the Kraken subvariant.

Arcturus has been found in 29 countries as of April 13, according to the WHO. India is experiencing a surge in cases, with over 60,000 COVID cases reported, its health ministry reported on Monday. Arcturus is replacing other variants in circulation on the subcontinent, according to WHO epidemiologist Maria Van Kerkhove during a press conference in March.

During that same press conference, Van Kerkhove said Arcturus is currently the most transmissible variant yet. New mutations in the virus spike protein now create the added potential to infect more easily, making Arcturus one to watch, Van Kerkhove added.

In the United States, cases of Arcturus have slowly ticked upward, accounting for 7.2% of COVID-19 infections in the U.S. during the week of April 915, according to the Centers for Disease Control and Prevention. Arcturus has been reported in 23 states, according to the CDCs COVID tracker.

In Massachusetts, Arcturus counts for less than 1% of cases thus far, according to the CDC. The state with the highest percentage of cases is Delaware, where almost 3% of COVID infections are Arcturus.

Arcturus is also distinct because of a new symptom not commonly seen with past COVID infections. Red, itchy eyes resembling conjunctivitis, or pink eye, has been seen among Indian children sick with the Arcturus subvariant, assistant dean of research and associate professor at the New York Institute of Technology Raj Rajnarayanan told Fortune.

Despite its rise, reported cases of Arcturus remain low in the United States. No hospitalizations or deaths as a result of Arcturus have been reported, but director of the Clinical Virology Laboratory at the Mayo Clinic Dr. Matthew Binnicker told NBC 5 Chicago that the strain may become more prominent in coming weeks.

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New COVID subvariant Arcturus reported in Mass. with new symptom

Senate GOP report raises possibility of two COVID lab leaks – New York Post

April 22, 2023

WASHINGTON The COVID-19 pandemic may have started with two separate leaks at Chinese labs doing risky gain of function research, a Republican senator said Monday.

A report released by Sen. Roger Marshall (R-Kan.) raises the prospect that millions of lives could have been saved including those of more than 1 million Americans if not for a coverup by the Chinese government during a theorized initial outbreak.

This report concludes most likely this was two leaks [including] a lab leak in the September-October [2019] timeframe, even as early as July or August, the medical doctor turned senator told a small group of journalists ahead of the release of the 301-page document.

Weve concluded that [China] started vaccine development in November 2019. And then another lab leak seems to be most sensible explanation, he said. There are key data points that are being held back that could help us prove that.

Dr. Robert Kadlec, a cofounder of the Operation Warp Speed program that rapidly developed US COVID-19 vaccines in 2020, drafted the report titled Muddy Waters: The Origins of COVID-19 with about a dozen Republican aides on the Senate Health Committee and additional outside consultants.

The theory that there were two lab leaks, with the first ones effect going unrecognized by the global community as the Chinese government raced ahead with early vaccine development, is unproven and Marshall says he welcomes debate and the exploration of other possibilities.

The theory rests on scientific conjecture about some previously reported details including an assessment of the amount of work that would have had to predate a Feb. 24, 2020, vaccine patent filed by Dr. Zhou Yusen, a Chinese military scientist who later died under mysterious circumstances. Investigators concluded that the vaccine development would have had to start in November 2019, using Operation Warp Speeds course as a benchmark.

A pre-November series of additional events adds weight to the theory, Marshall said, including the deaths of 11 Iranian athletes, publicly reported in 2020. Some of the athletes reportedly attended the Olympics-style World Military Games in held Wuhan, China, in October 2019.

There are additional scientific clues, according to the report.

Epidemiological and genetic molecular analyses of the early published circulating Wuhan [COVID-19] strains supported the possibility of two spillover events two or more weeks apart, the report says.

This assessment was made based on minor genetic differences in early circulating strains suggesting that two lineages of the same virus may have emerged simultaneously and progressed on different paths or sequentially separated by some period of time. One lineage showing more mutations than the other implying it had been circulated longer than the other or had potentially passed through more individuals.

The document goes on: A recently published study analyzed data from existing WHO global influenza surveillance networks early in the COVID-19 pandemic. Their analysis could identify outliers in influenza-negative influenza-like illness (ILI) that served as potential early indicator of COVID-19 communitytransmission.

The report noted [a] noticeable increase of Wuhan adult ILI cases during week 46 (November 11-17, 2019) corresponded to negative influenza testing that same week. This occurrence is similar to the epidemiological outlier identified in the published study. It occurs approximately 13 weeks before the recorded surge of COVID-19 cases in Wuhan in late January, early February 2020.

Further fueling suspicions, the Wuhan Institute of Virology deleted an online database of coronavirus samples on Sept. 12, 2019, which Marshall said likely would have shown cousins of COVID-19 if it was indeed from nature.

There are a lot of events around this timeline, then it gets a little quiet, and then boom, something else happens, Marshall said.

But Marshall concedes there may be alternative explanations for the outbreak, which Chinese authorities first publicly acknowledged on Dec. 31, 2019.

Pressed by The Post on whether the vaccine patent could have been quickly filed due to some other reason, the senator said, Im inviting that [challenge]. I think thats the whole purpose of science, to shoot down [competing] theories.

Marshall said he hopes the report will build momentum to establish a 9/11 Commission-style investigation of the origins of the virus to understand the reason for the devastating pandemic and to prevent a recurrence.

I dont think anyone can conclude that this is a get [Dr. Anthony] Fauci paper, said Marshall, who has clashed with the former top US infectious disease expert at hearings focused on American funding for the Wuhan lab that modified viruses to make them more contagious.

Marshall said that he believes Democratic colleagues are warming to an investigation of the pandemics origins and Ill be curious as to how the White House responds.

The White House did not immediately respond to The Posts request for comment.

President Biden on March 20 signed a bipartisan bill that mandates the declassification of records on the pandemics origins, though its unclear what material will be redacted.

Marshall said the US government hasnt yet been very forthcoming so far and that he hopes especially to further investigate the money trail flowing to Wuhan for research that modified coronavirus.

Every time I pick on China, we should look in the mirror because our own federal government has kept data from us, they wouldnt show us information. They wouldnt let us talk to the right people. So much of it is redacted, said Marshall, who took on leadership of the Health Committees GOP inquiry following the retirement in January of former Sen. Richard Burr (R-NC).

The senator also ridiculed an effort by what he called the gain of function mafia to push a theory that raccoon dogs farmed for their fur caused the pandemic, saying they would have been shipped around China leading to outbreaks in geographically distinct areas, rather than concentrated in Wuhan, where no animal or animal handler responsible for its origin has been put forward by the Chinese government.

In addition to safety issues reported at Wuhan labs, documents published in late 2021 byTheInterceptrevealed thatEcoHealthAlliance used US grants to fundWuhan Institute of Virologyexperiments that modified three bat coronaviruses distinct fromCOVID-19.Theresearch found the viruses became much more infectious among humanizedmicewhenhuman-type receptors were added to them.

Kadlec, who led the investigation, was assistant secretary for preparedness and response at the Department of Health and Human Services from 2017-2021. He previously worked as deputy staff director for the Senate Intelligence Committee.

The lab leak theory has gradually gained acceptance since 2020, when it was derided as a conspiracy theory.

The Wall Street Journal in February revealed that theEnergy Department, which operates the US National Laboratories, now believesthe pandemic began with a Chinese lab leak.

FBI DirectorChristopherWrayconfirmed the same monththat the FBI also believes COVID-19 leaked from a lab.

The FBI has for quite some time now assessed that theoriginsof the pandemic are most likely a potential lab incident in Wuhan,Wraysaid. Here you are talking about a potential leak from a Chinese government-controlled lab.

Under political pressure,Bidenin May 2021ordereda US intelligence community assessment of theoriginsof COVID-19, after previously saying the US would defer to the World Health Organization to get answers.

US spy agencies assessed in August 2021 thatit was plausiblethat the virus came either from a lab release in Wuhan or from a naturaloriginvia animal-to-human transmission.

At the time, a written statement attributed toBidensaid: The world deserves answers, and I will not rest until we get them.

Responsible nations do not shirk these kinds of responsibilities to the rest of the world, the statement said. Pandemics do not respect international borders, and we all must better understand how COVID-19 came to be in order to prevent further pandemics.

ButBiden, who campaigned heavily in 2020 on mourning pandemic deaths and slamming then-President Donald Trumps management of the crisis, has hardly mentioned the origins question since then even walking away from reporterson the White House lawn March 3 when asked about holding China accountable for the outbreak.

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Senate GOP report raises possibility of two COVID lab leaks - New York Post

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