Category: Corona Virus Vaccine

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Coronavirus Live Updates: All 50 States Have Begun to Reopen – The New York Times

May 20, 2020

All 50 states have begun to reopen, but vast discrepancies remain.

In Connecticut, flags that had been lowered to half-staff during the somber peak of the pandemic were raised high again to signal the states return to business.

In Kentucky, gift shops opened their doors.

And across Alaska, restaurants, bars and gyms, which have already been seeing customers for weeks, were getting ready to rev back up to full capacity. It will all be open, Gov. Mike Dunleavy announced, just like it was prior to the virus.

As of Wednesday, all 50 states had begun to reopen to some degree, two months after the outbreak thrust the country into lockdown. But vast variations remain in how states are deciding to open up, with some forging far ahead of others. Many began to reopen despite not meeting White House guidelines for progress against the virus, and newly reported cases have been increasing in some states, including Texas and Minnesota, that are moving to ease restrictions. Public health officials warn that moving too fast could risk more outbreaks.

The dynamic has left many business owners and customers to decide for themselves what they think is safe.

It is still a little scary, considering we dont exactly know what this is, said Ipakoi Grigoriadis, whose family owns Pops Family Restaurant in Milford, Conn., a diner that reopened its outdoor seating on Wednesday morning.

It is quite exciting to see our customers we havent seen in a while, she said. But it was not business as usual: Pops, like other Connecticut restaurants, now offers only outdoor seating and plans to gradually ramp up to 50 percent capacity. Servers are gloved and masked, and patrons are expected to wear masks as well, except when they are eating and drinking.

In New Jersey and many parts of New York State, the reopening has been more limited, with only curbside pickup at retail stores and allowances for certain industries.

Governors are increasingly facing intense pressure to reopen, as millions of Americans have lost their jobs and the unemployment rate reached a staggering 14.7 percent. But reopening in Texas, where businesses have been allowed to operate at 25 percent capacity for weeks, looks far different than it does in Illinois, where stores are still limited to curbside pickup.

States in the Northeast and on the West Coast, as well as Democratic-led states in the Midwest, have moved the most slowly toward reopening, with several governors taking a county-by-county approach. (In Washington, D.C., a stay-at-home order remains in effect until June.) By contrast, a number of states in the South opened earlier and more fully. Though social-distancing requirements were put in place, restaurants, salons, gyms and other businesses have been open in Georgia for several weeks.

In a medical research project nearly unrivaled in its ambition and scope, volunteers worldwide are rolling up their sleeves to receive experimental vaccines against the coronavirus only months after it was discovered.

Companies like Inovio and Pfizer have begun early tests of candidates in people to determine whether the vaccines are safe. Researchers at the University of Oxford in Britain say they could have a vaccine ready for emergency use as soon as September.

In labs around the world, there is now cautious optimism that a coronavirus vaccine, and perhaps more than one, will be ready sometime next year.

Scientists are exploring not just one approach to creating the vaccine, but at least four. So great is the urgency that they are combining trial phases and shortening a process that usually takes years, sometimes more than a decade.

What people dont realize is that normally vaccine development takes many years, sometimes decades, said Dr. Dan Barouch, a virologist at Beth Israel Deaconess Medical Center in Boston. And so trying to compress the whole vaccine process into 12 to 18 months is really unheard-of.

If that happens, it will be the fastest vaccine development program ever in history.

More than one hundred research teams around the world are taking aim at the virus from multiple angles.

A prototype vaccine has protected monkeys from the virus, researchers reported on Wednesday, a finding that offers new hope for effective human vaccines.

Scientists are already testing virus vaccines in people, but the initial trials are designed to determine safety, not how well a vaccine works. The research published Wednesday offers insight into what a vaccine must do to be effective and how to measure that.

To me, this is convincing that a vaccine is possible, said Dr. Nelson Michael, the director of the Center for Infectious Diseases Research at Walter Reed Army Institute of Research.

Scientists are engaged in a worldwide scramble to create a vaccine against the new virus. Over a hundred research projects have been launched; early safety trials in humans have been started or completed in nine of them.

Next to come are larger trials to determine whether these candidate vaccines are not just safe, but effective. But those results wont arrive for months.

In the meantime, Dr. Dan Barouch, a virologist at Beth Israel Deaconess Medical Center in Boston, and his colleagues have started a series of experiments on monkeys to get a broader look at how coronaviruses affect monkeys and whether vaccines could fight them. Their report was published in Science.

In one series of experiments, each monkey received pieces of DNA, which their cells turned into viral proteins designed to train the immune system to recognize the virus.

Most coronavirus vaccines are intended to coax the immune system to make antibodies that latch onto the spike protein and destroy the virus. Dr. Barouch and his colleagues tried out six variations.

Some of the vaccines provided only partial protection, but other vaccines worked better. The one that worked best trained the immune system to recognize and attack the entire spike protein of the coronavirus. In eight monkeys, the researchers couldnt detect the virus at all.

I think that overall this will be seen as very good news for the vaccine effort, said Dr. Barouch. This increases our optimism that a vaccine for Covid-19 will be possible.

The Centers for Disease Control and Prevention quietly released more detailed guidance for schools, businesses, transit systems and other industries hoping to reopen safely amid the coronavirus pandemic after fear that the White House had shelved the guidelines.

The 60-page document, which a C.D.C. spokesman said was uploaded over the weekend, but which received little notice, adds great detail to six charts that the C.D.C. had released last week. The guidance provides specific instructions for different sectors to detect and trace the virus based on exposure and risk after the pandemic. Here are some key elements.

If a person in a school building tests positive, schools should evaluate the risk and consider a brief dismissal of about 2-5 days, to clean and disinfect the building, coordinate with local health officials and contact trace. The C.D.C. offers different measures based on the level of community spread.

As restrictions across the country on restaurants and bars ease, the C.D.C. recommends owners give workers at a higher risk of getting sick a job that limits the persons interaction with customers. The agency also suggests opening with limited seating initially to allow for social distancing. Once fully reopened, the C.D.C. recommends having a clear policy about when employees should stay home if sick and rules on hygiene, including at times wearing face coverings.

When mass transit resumes its full service, the agency recommends being prepared to adjust routes based on the different levels of virus spread and to coordinate with local health officials about prevention strategies, such as wearing a face covering.

For businesses that provide child care during the pandemic, the C.D.C. recommends having plans in place, for example, to have substitute workers if staff members are sick, and requiring staff and children older than two to wear face coverings.

The guidance describes the balance of slowing the viruss spread with the economic threat of shuttering most businesses, and largely mirrors a draft version that was previously shelved by the White House, but with some changes.

The document omits a section on communities of faith that had troubled Trump administration officials and also tones down the guidance in several instances. For example, language that initially directed schools to ensure social distancing became promote social distancing, and the phrase if possible was added in several sentences.

Severe flooding struck central Michigan on Wednesday after two dams were breached by rain-swollen waters, forcing the evacuation of thousands of residents at a moment many had been wary of leaving their homes amid the pandemic.

Gov. Gretchen Whitmer implored residents to take the threat seriously and evacuate immediately, but added that they should continue to observe precautions related to the virus, including wearing masks and maintaining social distancing something she acknowledged would be difficult in the temporary shelters that had been set up.

To go through this in the midst of a global pandemic is almost unthinkable, she said. But we are here, and to the best of our ability we are going to navigate this together.

There have been at least 52,337 cases in Michigan, and at least 5,017 people have died.

The failures on Tuesday of the Edenville Dam and the Sanford Dam, about 140 miles northwest of Detroit, led the National Weather Service to issue a flash flood warning for areas near the Tittabawassee River. Residents in nearby towns, including Edenville, Sanford and Midland, were evacuated

As news of the disaster spread Wednesday morning, Mr. Trump took to Twitter and threatened to withhold federal funds to Michigan if the state proceeded to expand vote by mail efforts. (He made a similar threat against Nevada.) The president then followed up with a Tweet saying that the Federal Emergency Management Agency and the military had been deployed to Michigan to assist with disaster response.

The president is scheduled to visit a Ford Motor Co. plant that is manufacturing ventilators in Ypsilanti, Mich., on Thursday. This is his first trip to the state since January, and comes at a time when his campaign advisers are increasingly concerned about his chances there.

President Trump on Wednesday escalated his assault against voting by mail, making false claims about recent steps taken by Michigan and threatening to withhold federal funds from both states if they continue to expand vote-by-mail efforts.

The presidents latest broadside, on Twitter, came as the pandemic has raised concerns around the nation about how people can vote safely.

The president inaccurately accused Michigan of mailing ballots to its residents. In fact, its secretary of state sent applications for mail ballots, as election officials have done in other states, including those led by Republicans. A few hours later he sent another tweet correcting the earlier one, noting that Michigan had sent absentee ballot applications, but repeating the threat to withhold funding. He also threatened to withhold funds from Nevada, where the Republican secretary of state declared the primary an all-mail election, and where ballots are being sent to voters.

As most states largely abandon in-person voting because of health concerns, Mr. Trump, along with many of his Republican allies, have launched a series of false attacks to demonize mail voting as fraught with fraud and delivering an inherent advantage to Democratic candidates despite there being scant evidence for either claim.

Michigan sends absentee ballots to 7.7 million people ahead of Primaries and the General Election, the president tweeted Wednesday morning. This was done illegally and without authorization by a rogue Secretary of State. I will ask to hold up funding to Michigan if they want to go down this Voter Fraud path!

His threat to withhold federal funding cam as the state was grappling with a devastating flood; soon after he announced that the federal government would help.

An hour later he made a similar threat against Nevada, saying the state had created a great Voter Fraud scenario and adding If they do, I think I can hold up funds to the State.

Mr. Trumps outbursts come as the White House and his re-election campaign are confronting polls showing the president trailing his Democratic rival, Joseph R. Biden Jr., both nationally and in key swing states. The White House did not respond to requests for comment or elaboration.

Michigans secretary of state, Jocelyn Benson, quickly clarified on Wednesday that the state is not mailing ballots to all Michigan voters. On Wednesday she began mailing ballot applications to all registered voters.

I think that even at this time of stress and when people are so anxious and so confused, I think those religious ceremonies can be very comforting, he said. But we need to find out how to do it, and do it safely and do it smartly.

It is particularly significant for Jewish congregations, where a minyan, defined as 10 people over the age of 13, is required for a worship service.

Mr. Cuomo also released the results of antibody testing in some of low-income New York City neighborhoods hit hardest by the virus.

In many of them, more than 1 in 3 residents tested positive for antibodies, a far higher rate than citywide rate of about 20 percent, he said. In two neighborhoods, Brownsville in Brooklyn and Morrisania in the Bronx, more than 40 percent of people tested had antibodies.

Another public health hazard has surfaced in New York City amid the pandemic: Vaccination rates for childhood disease whooping cough, measles, chickenpox have dropped precipitously, putting children at risk, the mayor said.

The Justice Department warned California this week that it believed the states restrictions to combat the virus discriminated against religious institutions.

In a letter to Gov. Gavin Newsom, department officials complained that the states reopening plan allowed for restaurants and shopping malls to reopen before religious institutions could hold worship services. They also objected to the states current policy limiting how members of the clergy could be classified as essential workers.

Simply put, there is no pandemic exception to the U.S. Constitution and its Bill of Rights, said the letter from the head of the departments Civil Rights Division and the four U.S. attorneys in California.

The officials also said that while the department does not seek to dictate to California, they insisted that any restrictions must treat secular and religious activities equally.

A spokesman for Mr. Newsom, a Democrat, did not immediately respond to a request for comment.

Federal judges previously declined to block Mr. Newsoms restrictions on religious gatherings. In one case, brought by a church in Lodi, a Federal District Court judge denied a request for a temporary restraining order and wrote that in unusual circumstances like a pandemic, the judiciary must afford more deference to officials informed efforts to advance public health even when those measures encroach on otherwise protected conduct.

The Justice Departments missive to Mr. Newsom was not connected to any specific case, but it represented another phase of its efforts to curb state and local restrictions especially around religious institutions during the pandemic. Last month, the department went to court in support of a Baptist church in Mississippi that had challenged local restrictions.

Less than a week after lawmakers approved a major rule change, Speaker Nancy Pelosi on Wednesday formally initiated the remote work period for the House, jump-starting a 45-day period when remote voting can be used in the chamber.

With the move, the House will now be able to use proxy voting, which allows lawmakers to give specific instructions on each vote to a colleague authorized to vote on their behalf. Votes are expected in the chamber next week, and several lawmakers had previously expressed frustration with the need to travel to Washington during the coronavirus pandemic.

The announcement came after the Sergeant-at-arms, in consultation with Dr. Brian P. Monahan, the Capitol physician, sent Ms. Pelosi a letter formally notifying her of an ongoing public health emergency due to a novel coronavirus.

In direct contrast, however, Senator Mitch McConnell, on Wednesday highlighted the Senates ongoing presence in Washington, outlining how over here in the United States Senate, the lights are on, the doors are open, and we are working for the American people.

Mr. McConnell, the majority leader, thanked Dr. Monahan a Navy doctor whose office is responsible for the care of both chambers and the Supreme Court for his continued guidance, saying that it has allowed the Senate to operate smartly and safely during the pandemic.

The shuttering of the American education system severed students from more than just classrooms, friends and extracurricular activities. It has also cut off an estimated 55 million children and teenagers from school faculty whose open doors and compassionate advice helped them build self-esteem, navigate the pressures of adolescence and cope with trauma.

But the challenges hard-wired into online learning present daunting obstacles for the remote guidance counselors office, particularly among students from low-income families who have lost jobs or lack internet access at home. And mental health experts worry about the psychological toll on a younger generation that was already experiencing soaring rates of depression, anxiety and suicide before the pandemic.

Not every kid can be online and have a confidential conversation about how things are going at home with parents in earshot, said Seth Pollak, director of the Child Emotion Lab at the University of Wisconsin-Madison.

Desperate to safeguard students emotional well-being amid the isolation and financial turmoil, teachers are checking in during video classes, counselors are posting mindfulness videos on Facebook and school psychologists are holding therapy sessions over the phone.

Hospital executives and doctors, wary of what comes next, are asking whether this is a lull before a new wave of cases or a less chaotic slog. At hospitals, staff members are preparing for both possibilities.

Elmhurst is decontaminating rooms as managers try to persuade residents to come in now for emergencies and elective surgery as soon the governor lifts a ban imposed in March. Brooklyn Hospital Center is nervously waiting for those numbers to rise again.

At the same time, a new survey of nearly 23,000 nurses across the country shows continued concern over inadequate personal protective equipment as well as a lack of widespread testing among health care workers.

Many nurses remain fearful of becoming ill because they do not have the equipment they need to remain safe, according to the union that conducted the survey, National Nurses United, which has more than 150,000 members in the United States.

The survey, conducted from April 15 through May 10, includes responses from both union members and nonunion nurses in all 50 states. It found that a vast majority of nurses, 87 percent, reported having to reuse personal protective equipment, including respirators, a practice that the nurses said would not have been allowed before the pandemic.

More than 100 nurses have died of the disease, according to the union, and at least 500 of those surveyed said they had already tested positive. Eighty-four percent of those surveyed reported they had not yet been tested.

The aircraft carrier Theodore Roosevelt is set to return to sea in the next day or so after its deployment to the western Pacific was derailed by the outbreak, military officials said.

The Roosevelt has been docked in Guam for nearly two months, with much of its crew isolated in hotels and on the U.S. naval on the island. About 1,100 sailors from the Roosevelt have been infected since the outbreak began in March.

It is unclear whether the Roosevelt will return to Guam after its initial stint at sea; it might continue with its deployment that is set to end in July, officials said. If Navy officials choose the latter, the sailors left on Guam to recover from the illness are likely to be sent back to the United States, leaving the crew of the nuclear-powered carrier with only about 3,300 of its more than 4,800 crew members.

Navy officials said on Sunday that more than a dozen sailors on the ship had retested positive after they seemed to have recovered. The virus has forced the crew to take extraordinary measures to combat its spread in their cramped quarters: Sailors can be punished for not wearing masks, areas are cleaned at least twice a day, and if a crew member shows any signs or symptoms, they are promptly whisked off the ship.

Specialists including Dr. Anthony S. Fauci, the governments top infectious disease expert say the jury is still out on whether the drug might help prevent infection or help patients avoid hospitalization. Mr. Trumps frequent pronouncements and misstatements he has praised the drug as a game changer and a miracle are only complicating matters, politicizing the drug and creating a frenzy in the news media that is impeding research.

The virus is not Democrat or Republican, and hydroxychloroquine is not Democrat or Republican, and Im just hopeful that people would allow us to finish our scientific work, said Dr. William ONeill, an interventional cardiologist at Henry Ford Hospital in Detroit, who is studying hydroxychloroquine as a prophylactic in health care workers.

The worst thing in the world that would happen, he added, is that at the end of this epidemic, in late September, we dont have a cure or a preventive because we let politics interfere with the scientific process.

As he laid out his plans for the fall semester, the president of Purdue University, Mitch Daniels, said in an interview with CNN on Wednesday that young people faced essentially zero lethal risk from Covid-19.

The remarks from Mr. Daniels, who served two terms as Indianas governor, drew criticism online, as there is still much that is unknown about how the virus affects younger populations and how they might unknowingly spread the virus.

In March, data from the C.D.C. showed that nearly 40 percent of patients sick enough to be hospitalized were between 20 and 54 years old. More recently, neurologists in New York, New Jersey, Detroit and elsewhere have reported a sudden increase in unexplained strokes among younger patients that may be linked to the virus.

Mr. Daniels said that Purdue, in West Lafayette, Ind., would carry out a new hybrid approach to teaching that would protect both its staff members and students during the fall semester.

Weve learned over the past two months where the real risk and danger reside. That will be our area of focus with everything we do from physical facilities to the way we teach, Mr. Daniels said. Were going to have to work as hard on the cultural aspects as the physical.

New measures include having fewer people in classrooms, requiring masks for all students, building plexiglass barriers for teachers to stand behind and having students take at least one course online.

Students will also be expected to maintain social distancing, practice good hygiene, have their temperature taken daily and self-quarantine if they experience symptoms. The university will also be conducting testing and tracing, he said.

But amid C.D.C. warnings that the United States can expect multiple waves of infections until the development of a vaccine, the nearly 500,000-student California State University system announced last week that it would keep all of its 23 campuses mostly closed in the fall, holding classes primarily online.

Hundreds of migrant children and teenagers have been swiftly deported by American authorities during the pandemic without the opportunity to speak to a social worker or plea for asylum from the violence in their home countries a reversal of years of established practice for dealing with young foreigners who arrive in the United States.

The Trump administration is justifying the new practices under a 1944 law that grants the president broad power to block foreigners from entering the country to prevent the serious threat of a dangerous disease. And on Tuesday, it extended the stepped-up border security that allows for young migrants to be expelled at the border, saying the policy would remain in place indefinitely and be reviewed every 30 days.

In March and April, 915 young migrants were expelled shortly after reaching the American border, and 60 were shipped home from the interior of the country.

During the same period, at least 166 young migrants were allowed into the United States and afforded the safeguards that were once customary. Customs and Border Protection has refused to disclose how the government was determining which legal standards to apply to which children.

The fact that nobody knows who these kids are and there are hundreds of them is really terrifying, said Jennifer Nagda, policy director of the Young Center for Immigrant Childrens Rights. Theres no telling if theyve been returned to smugglers or into harms way.

As lockdowns are lifted, bacteria that built up internally in stagnant water, especially in the plumbing, may cause health problems for returning workers if the problem is not properly addressed by facilities managers. Employees and guests at hotels, gyms and other kinds of buildings may also be at risk.

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Coronavirus Live Updates: All 50 States Have Begun to Reopen - The New York Times

Coronavirus: Why a vaccine is still far away – The Indian Express

May 20, 2020

Written by Abantika Ghosh | New Delhi | Updated: May 20, 2020 6:50:07 pm A volunteer at trials, led by the University of Oxford, on the newly announced vaccine candidate against Covid-19. (Source: University of Oxford via AP/File)

Every time there has been news about a potential new vaccine against Covid-19, hopes have risen around the world. But some have also taken a realistic approach. Such as British PM Boris Johnson, a Covid-19 survivor himself, who has written in The Mail: There remains a very long way to go, and I must be frank that a vaccine might not come to fruitionWe need to find new ways to control the virus.

A series of stages

Development of a vaccine is a long process that can falter at any step. There is also the issue of effectiveness how the vaccine performs in real-life conditions against efficacy, which is performance in ideal conditions during trials.

Once a candidate is identified, its safety and efficacy have to be tested over three phases, as per protocols. A fourth stage involves collection and analysis of post-marketing data.

For Covid-19, there are over 100 vaccines being developed across the world now, some from scratch, some from existing molecules developed for other diseases.

Oxford University

Last month, the University of Oxford announced it is ready to trial its vaccine candidate, ChAdOx1 nCoV-19, developed from the common cold virus whose safety in humans is already established. ChAdOx1 nCoV-19 is made from a virus (ChAdOx1), which is a weakened version of a common cold virus (adenovirus) that causes infections in chimpanzees, that has been genetically changed so that it is impossible for it to grow in humans. Genetic material has been added to the ChAdOx1 construct, that is used to make proteins from the COVID-19 virus (SARS-CoV-2) called Spike glycoprotein (S), the University announced last month. This protein is found on the surface of SARS-CoV-2.

Last week, a paper, not yet peer-reviewed, gave out the results of the vaccine trial in macaques: We observed a significantly reduced viral load in bronchoalveolar lavage fluid and respiratory tract tissue of vaccinated animals challenged with SARS-CoV-2 compared with control animals, and no pneumonia was observed in vaccinated rhesus macaques. In other words, the vaccine did not prevent infection but it did prevent pneumonia.

CanSino Biologics

Hong Kong-listed firm CanSino Biologics is testing a vaccine. It announced last week that Phase 1 trials have been cleared and the vaccine is moving into Phase 2 based on the preliminary safety data of the Phase I clinical trial. The results of that trial have not been made public. This too is an adenovirus-based vaccine. The double-blind, placebo-controlled study in 500 healthy patients will be done in association with researchers from the Academy of Military Medical Sciences Institute of Biotechnology.

The National Research Council of Canada has said it would work with the company for development of its vaccine, Ad5-nCoV, in Canada.

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Another company, Sinovac, backed by the Chinese government, is working on a vaccine, and plans to produce 100 million shots a year, news reports said.

Imperial College London

The UK government is funding a vaccine effort at Imperial College London. Professor Robin Shattock, Head of Mucosal Infection and Immunity in the UK Department of Medicine, and his team developed the vaccine within 14 days of getting the gene sequence of the virus from China. It is not being tested in animals. The researchers plan to move to human trials soon and Professor Shattock has been quoted as saying that the vaccine could be available some time next year.

Inovio Pharmaceuticals

US-based Inovio Pharmaceuticals is working on a DNA vaccine candidate, INO-4800, and has got a grant from the Coalition for Epidemic Preparedness Innovations. In April it started Phase 1 clinical trials. It showed encouraging response in animal studies, the company has claimed.

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Coronavirus: Why a vaccine is still far away - The Indian Express

Blog post wrong on what Bill Gates said about COVID-19 vaccine – PolitiFact

May 20, 2020

Weve seen many social media posts lately that falsely claim Bill Gates is responsible for, or will somehow profit from, COVID-19.

Most claims are focused on the coronavirus vaccine. The Gates Foundation has been financially supporting the development of a vaccine and posting articles explaining the projected vaccine timeline.

A recent Facebook post links to an article titled, "Bill Gates Explains That The COVID Vaccine Will Use Experimental Technology And Permanently Alter Your DNA."

The post was flagged as part of Facebooks efforts to combat false news and misinformation on its News Feed. (Read more about our partnership with Facebook.)

The Waking Times blog post heavily quotes Bill Gates blog, specifically when he explains how RNA COVID-19 vaccines could be developed and how they would create antibodies.

RNA vaccines have been shown to create "a safe and long-lasting immune response in animal models and humans" in clinical and preclinical trials. However, licensed RNA vaccines have never been produced before.

The body creates proteins by translating mRNA, the messenger molecules from DNA. By introducing a new mRNA vaccine to a few cells in the human body, those cells will produce the proteins of "a disease-specific antigen," and the immune system can create an antigen-specific antibody. Basically, it creates only the parts of a pathogen that the body reacts to and creates antibodies to bond to. This way, the body can easily attack the disease when it recognizes its cells.

The second half of this claim, that these vaccines would "permanently alter your DNA" is incorrect. An article in Frontiers on Immunology analyzed new studies that found mRNA "cannot potentially integrate into the host genome and will be degraded naturally." Basically, after the messenger molecules create antigens for the body to react to, they will naturally stop being used and break down.

The Waking Times blog shared on Facebook asserts that a new COVID-19 RNA vaccine "will not be tested in any significant or standard capacity" and that readers should prepare to be "guinea pigs in the largest global health experiment ever."

But Gates makes it very clear throughout his own blog post that scientists are not just relying on RNA or DNA experiments to create the first worldwide COVID-19 vaccine. "As of April 9, there are 115 different COVID-19 vaccine candidates in the development pipeline," Gates writes. RNA and DNA vaccines are easier to produce and they are testing them right now, but "even if an RNA vaccine continues to show promise, we still must continue pursuing the other options."

Contrary to the explosive claim that the entire world would be treated as "guinea pigs" for a new RNA or DNA vaccine, Gates explains how any COVID-19 vaccine will go through a rigorous, but also shortened, testing period. The New England Journal of Medicine has projected that they can shorten the usual 5-year period of vaccine testing to three short testing trials over 18 months. Gates says later in his article that its a priority to "make sure we have good real-world evidence that the vaccine is completely safe to use."

RNA testing will be done on small groups before it reaches the entire world. The first round of clinical testing with an RNA vaccine for COVID-19 began on May 16th. The dosage test has only 105 subjects and is projected to take at least a year to complete.

Our Ruling

A blog post shared on social media reads "Bill Gates Explains That The COVID Vaccine Will Use Experimental Technology And Permanently Alter Your DNA."

This is inaccurate. Gates never said that the first licensed COVID-19 vaccine would use experimental technology or permanently alter DNA;he said specifically that "we dont know yet what the COVID-19 vaccine will look like." The most recent research also shows that RNA vaccines, which are being tested for COVID-19 right now, do degrade naturally and dont alter DNA permanently. We rate this claim False.

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Blog post wrong on what Bill Gates said about COVID-19 vaccine - PolitiFact

A mink may have infected a human with Covid-19, Dutch authorities believe – CNN

May 20, 2020

"On the basis of new research results from the ongoing research into Covid-19 infections at mink farms, it is plausible that an infection took place from mink to human," the Dutch government said in a statement late Tuesday night.

"It also appears from this research that minks can have Covid-19 without displaying symptoms."

The government said antibody testing of minks would be expanded to "all mink farms in the Netherlands and will become mandatory."

The government also said it believes cats may be playing a role in the spread of the virus between farms. "Ongoing research shows the viruses at two of the infected farms are very similar," the statement said. Covid-19 was found in three out of 11 cats at one mink farm, it said.

"In the course of this investigation, it is advised that infected mink farms ensure that cats cannot enter or leave the farm premises."

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A mink may have infected a human with Covid-19, Dutch authorities believe - CNN

Avery County reports first case of COVID-19, all 100 N.C. counties now have a confirmed case – WBTV

May 19, 2020

As our counties start opening back up its important to remember that COVID-19 is still here, added Diane Creek, Toe River Health District Health Director. We are blessed in Avery County to have a strong community. Your public officials and county leadership have been working tirelessly to prepare for the impact of this virus. Community members can do their part by continuing to follow the guidelines, and remember that were all in this together, and to support one another.

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Avery County reports first case of COVID-19, all 100 N.C. counties now have a confirmed case - WBTV

Coronavirus pandemic: Updates from around the world – CNN International

May 19, 2020

A man from Winter Springs, Florida, told CNN on Monday that he has been stuck on a cruise ship and then a hospital ship in an Italian port for 62 days after testing positive for Covid-19 in early April.

Grimes set sail mid-January from Genoa, Italy, on his second cruise as an employee of MSC Cruises, a global cruise company headquartered in Geneva, Switzerland. Grimes worked in the jewelry store on their Mediterranean route.

On March 17, a friend of Grimes and fellow employee tested positive for Covid-19, Grimes said. After consulting with the ship doctor and captain, Grimes said he "voluntarily went into isolation." Fifteen days later, he also tested positive, Grimes said.

Grimes has since been tested seven more times and has received a mixture of positive and negative results, he said.

Grimes said he hopes his eighth Covid-19 test result will be negative, so he can return to the United States.

The American Embassy confirmed to the family it is Italian policy that cruise ship employees may not be released from a ship until they have tested negative in two subsequent tests, Ann Grimes said.

"We don't question that that's the standard," Ann Grimes said. "It's the fact the testing is so sketchy. How can you be in quarantine for 62 consecutive days and still be testing positive?"

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Coronavirus pandemic: Updates from around the world - CNN International

Former WHO board member warns world against coronavirus ‘vaccine nationalism’ – The Guardian

May 19, 2020

A coronavirus vaccine will result in significant calls to supply locals first, a form of vaccine nationalism that will leave all worse off, the chair of the Coalition for Epidemic Preparedness Innovations has warned.

Jane Halton, who is also a former head of Australias health and finance departments, issued the warning at the National Press Club on Monday.

Halton told reporters there is a reasonable chance of developing a Covid-19 vaccine because although 94% of vaccine candidates fail there are 130 groups working on the problem worldwide.

With seven different categories of vaccine on trial and 20 candidates in the other category, Halton said the scientific community is doing well to get the maximum shots on goal.

The Coalition for Epidemic Preparedness Innovations has backed 10 candidates, including one in Australia that could go to human trials as early as July.

If a vaccine is identified, production should be globally distributed to guard against vaccine nationalism, she said.

A vaccine is critical to returning to work, global trade and tourism, so if we have vaccine nationalism, and one country looks after itself first, and at the expense of the rest of the world, everyone is going to continue to suffer, Halton said.

The World Health Organization is working out a list of priority recipients including first-responder health workers, the elderly and immunocompromised.

Now, this is hard, because its going to require people to cooperate.

And the urge for domestic priority, I think, will be very significant.

After a country has produced a vaccine and served its vulnerable citizens it will need to determine what share of that is going to vulnerable people around the world at the same time, Halton said.

At the moment, were all in it together. As soon as there is a vaccine, I fear that we may not be quite all in this together as we have been.

Halton, a member of the WHO board for three years, said she could understand the concerns of our friends in China about being blamed for Covid-19 but defended a proposed investigation into the zoonotic origins of the virus as the best way to prevent it from happening in the future.

Halton, also a commissioner in Australias national Covid-19 Coordination Commission, warned against complacency now Australia has begun to ease restrictions.

She said a its all good attitude would reduce social distancing and could cause a really bad outcome for the elderly and immunocompromised.

Halton said the Australian states do not work in hermetically sealed spheres and although she understood states being nervous about taking down internal border controls, she was not convinced current border controls were the best way to manage risk.

Halton also foreshadowed a greater role for the commission in planning Australias economic recovery after the immediate challenges of ensuring enough personal protective equipment had been met.

The commissions chairman, Nev Power, has publicly backed a fertiliser plant and spruiked natural gass role in powering domestic manufacturing since taking the role.

We will turn our focus to what is actually going to get our economy kickstarted, Halton said.

What we want to be able to see is an increase in productivity in our economy. And we will be working with the government on what some of those ideas might be.

Read the rest here:

Former WHO board member warns world against coronavirus 'vaccine nationalism' - The Guardian

Coronavirus: Where California stands as most of the state enters Phase 2 of reopening – The Mercury News

May 19, 2020

All of the Bay Area and the majority of California has now entered the second of four phases in Gov. Gavin Newsoms plan to reopen the state. Curbside retail, manufacturing plants and offices will be allowed to resume operations around the state in all but Los Angeles and Sacramento counties.

But the number of new cases of COVID-19 continues to come in the thousands, with days of triple-digit fatalities. The most recent of which came three days ago, with 107 deaths reported Friday amounting to the states second-deadliest day of the outbreak.

[ FAQ: What does it mean to enter Phase 2? Which parts of the state qualify? ]

Another 84 Californians succumbed to the virus over the weekend, including 33 on Sunday to bring the death toll to 3,240, according to data compiled by this news organization, while the state crossed 80,000 total confirmed cases with another 1,433 positive tests reported Sunday.

The states pace of growth remained exactly the same as the week prior: 18% more cases and 17% more fatalities.

Los Angeles County continues to account for a large chunk of the growth statewide, but more than half of the new cases Sunday came in counties moving forward with reopening. Of the 84 deaths over the weekend, 66 occurred in LA County, while the other 18 came in counties that have entered Phase 2.

The Bay Area, while still outpaced by Southern California, has seen an increase in new cases the past three days. The 10-county region added another 349 confirmed cases over the weekend, or just over 10% of the statewide gain still below its proportion of the population but slightly higher than in past days.

Alameda led the growth with 92 new cases from Friday to Sunday, followed by San Francisco (65), Santa Clara (50), Contra Costa (46) and San Mateo (27). In Southern California, the largest increases have come in Los Angeles (1,715), San Diego (313), Orange (251) and San Bernardino (200).

A number of mostly rural Northern California counties have been approved to accelerate the reopening of restaurants and shopping malls, too, in an advanced stage of Phase 2. But to qualify for that, counties cannot have recorded a fatality from the virus in the past 14 days, in addition to a number of other criteria.

One death in Alameda County was the regions lone fatality over the weekend, and hospitalization rates continue to decrease. The number of COVID-19 patients hospitalized across the Bay Area dropped to 252 on Friday, the most recent day for which data was available, the lowest it has been since April 1.

Statewide, hospitalizations hit one-month low on Sunday, with 3,037 patients in hospital beds, the lowest number since April 13. That number has fallen 11.3% since the beginning of the month, while the number of patients in ICUs has dropped by 8.7%.

As new cases and deaths plateau and hospitalizations decrease slightly, the state has ramped up testing but not yet to the goals Newsom set last month. Labs around the state performed 200,000 tests last week, about 12,000 more than the week before and 75,000 more than three weeks ago. But that still only amounts to 7 of every 10,000 Californians being tested each day.

Newsom had set a goal of 25,000 tests per day by the end of April, which the state accomplished, but also an eventual capacity of 60,000 to 80,000 per day. Entering the third week of May and the eighth week since the Bay Areas shelter-in-place mandate the state has yet to conduct more than 36,000 tests in a single day.

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Coronavirus: Where California stands as most of the state enters Phase 2 of reopening - The Mercury News

Stock Market News: The 3 Stocks That Need a Coronavirus Vaccine the Most – Motley Fool

May 19, 2020

Monday brought renewed enthusiasm to Wall Street as investors looked favorably on efforts to reopen the U.S. economy. With several states implementing new procedures to allow businesses to open, millions of Americans are looking forward to getting back to some semblance of normal life. Market participants also reacted positively to comments from Federal Reserve Chair Jerome Powell Sunday night that lent credibility to the idea that the central bank still has ways to help in the economic fight against the pandemic's effects. Just after 11 a.m. EDT, the Dow Jones Industrial Average (DJINDICES:^DJI) was up 806 points to 24,492. The S&P 500 (SNPINDEX:^GSPC) rose 86 points to 2,950, and the Nasdaq Composite (NASDAQINDEX:^IXIC) picked up 218 points to 9,233.

One of the things that buoyed sentiment among investors was the effort to develop a coronavirus vaccine. Shares of Moderna (NASDAQ:MRNA) were higher by 23% following positive results from early tests of its COVID-19 vaccine in humans. Certainly early-phase trials of vaccine candidates will have a direct impact on the pharmaceutical and biotech stocks sponsoring them. But in the long run, the three stocks that stand to gain the most from a coronavirus vaccine are cruise ship operators Carnival (NYSE:CCL), Norwegian Cruise Line Holdings (NYSE:NCLH), and Royal Caribbean (NYSE:RCL). That's a big part of why the three cruise ship stocks are up between 13% and 18% Monday morning.

Image source: Getty Images.

The key to the stock market rally over the past couple of months has been hope that returning to business as usual is still an option in the long run. In particular, the need to get businesses moving forward as soon as possible can be felt in communities across the nation.

Most businesses, with the guidance of health officials, could take steps to reopen while still offering some protection against coronavirus contagion. We'll see some of those steps in the months ahead, including limiting the number of people in stores at any one time, reserving certain times for customers at highest risk of serious illness, and requiring the use of personal protective equipment.

Yet cruise ship operators would have a difficult time adapting their business models to meet stopgap regulatory guidelines. Inherent in the cruise ship experience is large groups of people traveling together within an enclosed environment for several days and periodically going ashore at various locations to spend time interacting with locals.

Cruise companies could try to impose new restrictions on travelers, such as by keeping groups of passengers in their cabins to limit the number of people congregating at any one time. However, that would detract from the entire point of a cruise. Moreover, enforcing those requirements would bring up many of the same troubles that state and local governments have run into trying to enforce lockdown and stay-at-home orders.

In that light, it makes sense that a full vaccine would be the best solution for cruise ship operators. That way, bullish investors figure, companies like Royal Caribbean, Norwegian, and Carnival can largely return to their former operating models. With protection against the coronavirus in place, passengers would feel just as comfortable as they did before the pandemic struck.

The big question is timing. Even with fast-tracked efforts to develop a vaccine, researchers are still only in the early stages. Meanwhile, cruise ship operators have canceled months' worth of voyages, and although they've raised capital to get through a period of essentially no revenue, there's a limit to how much liquidity they'll be able to get. That leaves these companies in a race against time, with no certainty about whether they'll outlast the outbreak.

The healthcare stocks developing a vaccine have been volatile, with prices soaring when prospects for a particular company's vaccine look good. But for cruise ship stocks, a vaccine is even more important -- because the industry's entire future could rest on a reliable way to prevent the illness from ever taking hold again.

See more here:

Stock Market News: The 3 Stocks That Need a Coronavirus Vaccine the Most - Motley Fool

Scientists believe they found potential coronavirus vaccine

May 17, 2020

Scientists at the University of Pittsburgh School of Medicine believe that theyve found a potential vaccine for the new coronavirus.

The researchers announced their findings Thursday and believe the vaccine could be rolled out quickly enough to significantly impact the spread of disease, according to their study published in EBioMedicine.

The vaccine would be delivered on a fingertip-size patch. When tested on mice, the vaccine produced enough antibodies believed to successfully counteract the virus.

The scientists say they were able to act fast because they had already done research on the similar coronaviruses SARS and MERS.

These two viruses, which are closely related to SARS-CoV-2, teach us that a particular protein, called a spike protein, is important for inducing immunity against the virus, read a statement from co-senior author Andrea Gambotto, M.D., associate professor of surgery at the Pitt School of Medicine.

We knew exactly where to fight this new virus.

The vaccine follows the traditional approach of ordinary flu vaccines, using lab-made pieces of viral protein to build immunity.

While the mice have not been studied over a long period of time, the vaccine was able to deliver enough antibodies against the coronavirus within two weeks, according to the researchers.

The studys authors are now applying for an investigational new drug approval from the US Food and Drug Administration. They hope to start human clinical trials within the next few months.

Researchers said they sided with using a patch, rather than a traditional needle, to deliver the spike protein to the skin, which elicits the strongest immune reaction.

The patch contains 400 tiny microneedles made of sugar and protein pieces. It would be applied like a Band-Aid with the needles dissolving into the skin.

The vaccine would be highly scalable for widespread use, the researchers said in a news release.

For most vaccines, you dont need to address scalability to begin with, Gambotto said. But when you try to develop a vaccine quickly against a pandemic, thats the first requirement.

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Scientists believe they found potential coronavirus vaccine

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