Category: Corona Virus Vaccine

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COVID-19: What you need to know about the coronavirus pandemic on 26 October – World Economic Forum

October 26, 2020

1. How COVID-19 is affecting the globe

Confirmed cases of COVID-19 have now passed 43 million globally, according to the Johns Hopkins Coronavirus Resource Center. The number of confirmed deaths stands at over 1.15 million.

The Irish government expects to be able to start vaccinating vulnerable people against COVID-19 in the first half of next year, Deputy Prime Minister Leo Varadkar yesterday.

Most remaining restrictions in Melbourne, Australia, will start to be eased from tomorrow. It comes after no new cases were reported in 24 hours - the first time that had happened in four months.

Spain's Prime Minister has announced a new state of emergency. Local nighttime curfews have been imposed and travel is banned between regions in some cases.

France has registered a record daily tally of new COVID-19 cases - 52,010. The new cases take its total to 1,138,507, moving it ahead of Argentina and Spain.

The Czech Republic is likely to increase restrictions, as current measures have not halted a surge in infections, Prime Minister Andrej Babis said yesterday.

The Financial Times has reported that a coronavirus vaccine being developed by the University of Oxford, working with AstraZeneca, produced a robust immune response in elderly people, according to early results from tests.

As part of work identifying promising technology use cases to combat COVID, The Boston Consulting Group recently used contextual AI to analyze more than 150 million English language media articles from 30 countries published between December 2019 to May 2020.

The result is a compendium of hundreds of technology use cases. It more than triples the number of solutions, providing better visibility into the diverse uses of technology for the COVID-19 response.

To see a full list of 200+ exciting technology use cases during COVID please follow this link.

2. Record cases in the US

The United States has reported its highest number of new COVID-19 cases on Friday and Saturday. A record 84,244 new cases were reported on Friday, and throughout October records for daily increases in new cases have been set in 29 states.

A Reuters tally also shows that hospitalizations have hit a two-month high.

The city of El Paso, Texas, has responded by asking its residents to stay home for the next two weeks, with parks and recreational facilities closed in El Paso county. A curfew was also introduced yesterday, from 10pm to 5am.

For the sake of those hospitalized and the frontline healthcare workers working tirelessly each day to care for them, we ask you to please stay home for two weeks and eliminate your interactions with those outside your household until we can flatten the curve, said the citys public health director, Angela Mora.

In total, more than 8 million cases have been reported across the US.

Image: Our World in Data

3. Restrictions tightened in Italy

Restrictions have been increased in Italy, in response to rising cases.

Bars and restaurants will have to close by 6pm, while public gyms, cinemas and swimming pools are being forced to close completely.

We think we will suffer a bit this month but by gritting our teeth with these restrictions, well be able to breathe again in December, Prime Minister Giuseppe Conte said.

The country reported a record daily total for new cases on Sunday - 21,273.

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COVID-19: What you need to know about the coronavirus pandemic on 26 October - World Economic Forum

New Wave Of COVID-19 In Illinois Has Doctors On Notice, But They Emphasize How Much More Is Known About Virus – CBS Chicago

October 26, 2020

CHICAGO (CBS) The Centers for Disease Control and Prevention said over the past week, Illinois has the second highest COVID-19 case count in the U.S.

This new wave of the virus has local doctors paying close attention. CBS 2s Steven Graves on Sunday asked how hospitals were preparing.

Doctors around Chicago are quick to point out that their understanding of COVID-19> is much better now than it was two months ago.

How do you take care of patients with COVID? How do you respond? said Dr. Bala Hota, who studies COVID-19 data at Rush University Medical Center.

Were definitely more prepared, but its unclear how big this wave will be, said Dr. Nishant Agarwal, a surgeon at the University of Chicago Medical Center.

This week, COVID-19 cases hit more than 400,000. CDC data shows Illinois was the second highest contributor after Texas.

While that is shocking, doctors said it does not tell the whole story.

When you look at the cases per 100,000, we are much lower, Hota said. Were about in the middle of the country.

But that does not mean there is an excuse to relax. Physicians said while right now, hospitalizations are only slightly up, the next two to four weeks are crucial.

Hospitalizations do lag compared to increases in testing rates, so we may start seeing an increase in hospitalizations, Hota said.

But much has changed at hospitals from managing patients to the screening process and testing.

Dr. Agarwal, a surgeon, is on a team developing a saliva test. He said the better the testing methods, the safer hospitals are to stay up and running.

[Protocols] were put in place the surge in spring to just sort of keep the patients, their families, and the health care staff safe, he said.

Another change is that the therapeutic remdesivir now has full Food and Drug Administration approval. That means hospitals have more access to use it on some of the most critical patients.

I mean, there has been ample supply, Hota said.

Doctors said social distancing, hand washing, and masking up are still the best ways to stop the spread. They expressed hope that the holiday season does not take things in the wrong direction.

Were hopeful that the trends reverse, Hota said, but if things start to change, were ready.

Rush has teams involved in clinical trials to develop a vaccine. The staff projects it will be tested and available early next year.

Also From CBS Chicago:

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New Wave Of COVID-19 In Illinois Has Doctors On Notice, But They Emphasize How Much More Is Known About Virus - CBS Chicago

Alaska’s second wave of COVID-19 is bringing surging daily case counts, more hospitalizations and a new foe: fatalism. – Anchorage Daily News

October 26, 2020

Alaska is in the midst of a second wave of coronavirus thats setting new records and shows no sign of slowing.

Case numbers are surging in Anchorage and Fairbanks but also in isolated, medically underserved rural communities including the Yukon River delta village of Chevak where nearly 18% of the population tested positive in the space of just a few days.

Statewide, there are so many people testing positive that public health workers cant keep up with the contact tracing thats a central part of Alaskas strategy to contain coronavirus.

Alaska statewide case-count records were shattered on Saturday, with 355 new cases reported, then again Sunday with 526 cases. The numbers of people hospitalized in Alaska with COVID-19 hit its highest level at one time so far on Friday, at 59, and 58 were reported hospitalized on Sunday. Hospitalizations are considered a lagging indicator, meaning people admitted to the hospital with COVID-19 may have tested positive weeks earlier.

Health officials in increasingly urgent messages say the only way to rein in the surging case numbers is for individual Alaskans to take voluntary steps theyve been pushing for months: Wear a mask, practice social distancing, avoid gatherings outside the home.

But theyre running up against public pushback amid rising levels of COVID fatigue thats only growing as the pandemic months pass.

The biggest challenge I feel these days is a sense of, when I talk to the public and community leaders, is fatalism, the states chief medical officer, Dr. Anne Zink, said during a recent briefing. Thats harder to combat than getting more testing or supplies.

Asked if its too late to stop the continued spread of the virus in Alaska, the states two top health officials both simultaneously shout, NO!

Its not too late for us to stop this surge in cases, said state epidemiologist Dr. Joe McLaughlin. We know what works with COVID. Weve demonstrated it in Alaska, weve demonstrated it in the United States, and weve demonstrated in multiple countries across the globe: mitigation works.

Gov. Mike Dunleavy seems to take a longer view, contending that state officials expected to see case counts going up and he expects that trend to continue.

Dunleavy says that despite rising numbers, the states hospitals are holding steady and thats one indicator the states response is working. Alaskas death rates from COVID-19 are falling even as cases increase, he said, and the vast majority of deaths are in people with underlying health conditions.

The governor continues to avoid imposing statewide mandates for masking or stay-at-home orders, preferring localized restrictions. Multiple cities including Anchorage, Fairbanks, Unalaska and Juneau have instituted mask mandates in some form. Multiple rural villages are currently in lockdown.

Dunleavy held the first COVID-19 news conference in weeks, streamed via Facebook, last Wednesday. He called the virus very very very infectious and said the state is going to see case numbers continue to rise.

Asked in an interview on Friday about his message compared to those from his top health officials, the governor said he didnt know if there was necessarily a conflict between saying cases are expected to rise and the assertion Alaskans can slow the spread of the virus.

The governor said hes trying to strike a balance as the nation approaches a potential vaccine in the coming months.

We made the assumption that the cases would rise because of its infectious nature, and a lack of a vaccination, Dunleavy said in the interview.

The state could take more restrictive steps to stop the spread of the illness, he said, but that would involve extraordinary measures, in the way of shutdowns enforced by sanctions and arrests.

Certainly, we could probably shut the virus down, Dunleavy said Friday. But then the cost to do that would be, in my opinion, astronomical.

In a Facebook post Sunday, Dunleavy said, With yesterday and todays case counts, it is clear that Alaska has entered an acceleration phase with regard to the virus, though this is not unexpected as Alaskans moved indoors with the changing seasons. The vast majority of the new cases are with individuals younger than age 60, and our hospitalization and mortality rates are still at very low levels per capita...Nothing is going to replace individual action and responsibility, including social distancing, wearing a mask around others, and washing your hands. Together we can slow the widespread community transmission and protect the most vulnerable."

At first, Alaska kept the virus at bay. Then over the summer a spike in cases was tied to major outbreaks in the seafood industry and leveled off before dropping.

Now cases are in full-on acceleration mode as positive test counts hit new records each week, health officials say.

Asked where people are getting the virus, one infectious disease specialist had a one-word answer: Everywhere.

Most Alaskans get COVID-19 from someone they work, socialize, or go to school with, according to a state update this week. Many report that they went to social gatherings, community events, church services and other social venues while they were contagious but before they knew they had the virus.

The common denominator these days is as much behavior as it is a physical location, said Anchorage Health Department epidemiologist Janet Johnston.

The places where people are keeping their distance and wearing a mask, we have less transmission," Johnston said.

With winter approaching, more people are moving indoors where the virus spreads more easily. And cases are moving into older populations after predominating in younger people, a group that over the summer drove up new positive tests but generally stayed healthy enough to not need hospital care.

If Alaska follows national trends, the shift into older age groups could predict a rise in hospitalizations and deaths.

Florist Natasha Price makes a flower arrangement in her garage on Wednesday, Oct. 21, 2020. Price said her business Paper Peony is thriving during the pandemic. (Bill Roth / ADN)

Natasha Price, an Anchorage florist, said despite the months that have passed amid a global pandemic, she tries to follow public-health guidelines and remains cautious about socializing. She decided to see a therapist for the first time in her life, via telemedicine.

Price hears younger friends talk about going to restaurants. She has zero interest in doing that.

It seems that the numbers are an all-time high in Alaska right now, she said. And I find that deeply concerning.

Alaskans, like people around the country and the world, are tired of staying home and not seeing friends and family. Theyre financially gutted by lost jobs and rent bills coming due. Many have dug in on one side or the other mask up or stay uncovered, go out or hole up, avoid the virus or get infected and boost herd immunity.

Some people dont answer their phones when contact tracers finally do call. Others say they dont want to get tested even if theyve been exposed because they cant afford to lose time off work.

Dr. Bruce Chandler, Anchorage Health Department medical officer, heard recently about a symptomatic staff member at a residential care facility who continued to work while waiting for a COVID-19 test result.

One person this week reported having to work several days with customers while infectious because their boss threatened to fire her if she didnt show up to work, Chandler said during a briefing.

Theres also strong pushback against any restrictions at all. The governors former chief of staff, Tuckerman Babcock, is an administrator of a private Facebook group with more than 7,000 members called OpenAlaska that agitates against mask wearing and pandemic protocols.

No public health emergency. All mandates should be lifted and the land of the free and home of the brave restored," Babcock posted Friday.

Everybody is tired of coronavirus, it seems. Even the governor.

Dunleavy, who was captured not wearing a mask at a Republican fundraising event earlier this month, said he generally wears one except when hes eating, drinking or speaking publicly. The governor said he wears a mask in state office buildings, at the store, and when hes "mixing with the public.

He said he takes one off when hes speaking to a group for long periods of time even though it increases the risk of the virus.

But I also think there needs to be a little fairness and understanding in that I probably altered my life 80 to 90%, Dunleavy said, listing some of the changes including leaving the state by plane just once since February, limited face-to-face meetings and reduced in-state travel.

I could go on and on and on but the point Im trying to make is, there are times that youre going to wear a mask and you should do it as much as possible," he said. "And there are times that youre not and the times that youre not, I dont think should be, you know, considered an attempt at harming people.

Wasilla resident Helen Lindsey pulled on a surgical mask as she and her husband got out of their sedan at Three Bears, a grocery chain that does not require customers wear face coverings.

Inside, maybe half the customers and some cashiers wore them too.

The store where Lindsey works does require face covers. She was asked to hand them out to customers not wearing them. People cursed at her, yelled in her face, and threw the masks back at her.

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Lindsey said she doesnt like the pandemic restrictions any more than the next person. She had no physical contact with her husband, Mike, for weeks after he broke his leg over the summer and ended up in the hospital and then rehab. They talked by phone, separated by glass.

She feels like her family has buckled down enough. Its time for other people to start following protocols.

Im so sick of it, she said.

Some people dont seem to take the virus seriously unless they experience it first-hand, medical providers say. Statistics show that about 20% of Alaskans hospitalized with COVID-19 will die.

Dr. Nicholas Papacostas, who serves as vice president of the Alaska chapter of the American College of Emergency Physicians, said his emergency room colleagues worry theyll be stretched thin unless Alaskans start taking steps to slow the spread of the virus.

The underlying concern is that hospitals could hit full capacity and then go past it, even with surge plans hospitals already have in place. That could compromise staffing ratios and degrade the level of care.

Its heartbreaking to actually lay hands on one of these patients and have the sinking feeling as you care for them in the ER that this person is heading for the ICU and statistically theyre not going to do well, and open their chart a week or even a month later and see they did in fact die, said Papacostas, who practices emergency medicine in Anchorage.

Its real. Theres real suffering happening, he said. And I dont know how to make people understand that.

Reporter Zaz Hollander reported from the Mat-Su. Morgan Krakow and Annie Berman reported from Anchorage.

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Alaska's second wave of COVID-19 is bringing surging daily case counts, more hospitalizations and a new foe: fatalism. - Anchorage Daily News

Pennsylvania COVID-19 cases still spiking, seven-day average on pace to surpass first peak; new wave of hospit – The Philadelphia Inquirer

October 26, 2020

Pennsylvania reported 2,043 new cases on Saturday, the third-straight day with more than 2,000 cases (the Department of Health didnt release numbers on Sunday). The commonwealth is now averaging 1,668 new cases a day over the past seven days, just shy of the pandemic high of 1,685 new daily cases set back in mid-April.

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Pennsylvania COVID-19 cases still spiking, seven-day average on pace to surpass first peak; new wave of hospit - The Philadelphia Inquirer

Maine reports 58 new cases of COVID-19 – Press Herald

October 26, 2020

Maine reported 58 new cases of COVID-19 on Monday, continuing a trend of rising case numbers.

The seven-day average of daily new cases climbed to 45.1 on Monday, compared to 35 late last week, and 29.1 a month ago.

Cumberland County reported 13 new cases and York and Penobscot counties both reported seven. Waldo and Androscoggin counties each had three new cases.

There were no additional deaths reported.

An outbreak connected to Brooks Pentecostal Church in Waldo County has been linked to 57 COVID-19 cases through Friday. The growth in case numbers in the county spurred the Maine Department of Education to change the countys school risk level from green to yellow, which has led to a halt in high school sports and extra-curricular activities.

The University of New England in Biddeford has also reported a recent outbreak. Three students tested positive last week after attending an off-campus event, and all have either returned home or moved into isolation.

And South Portland High School last weekend reported that an individual associated with the school has tested positive for COVID-19, the first case in the district. Those who were in close contact with the individual are required to quarantine and testing is recommended. The high school was not closed.

Nationwide, cases are soaring, with more than 8.9 million cases and 230,000 deaths since the pandemic began.

This story will be updated.

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Maine reports 58 new cases of COVID-19 - Press Herald

Latest on COVID-19 in MN: Nearly 4,000 more cases, 35 deaths over the weekend – Minnesota Public Radio News

October 26, 2020

Minnesota health officials reported nearly 4,000 more confirmed COVID-19 cases and 35 more deaths over the weekend

The state has averaged 16 COVID-19 deaths a day over the past week that's a level not seen since June. The average number of new hospitalizations each day also continues to climb.

The number of active COVID-19 cases in the state reached a record high on Saturday at more than 13,000. The number ticked down slightly on Sunday, to 12,968; it was 8,171 on Oct. 1.

The weekly average for test positivity rate in Minnesota was at 6.7 percent on Sunday down slightly from Saturday, but well above the 4.6 percent rate at the start of the month.

There is more disease out there, and not just because were doing more testing, Health Commissioner Jan Malcolm told reporters Friday.

Here are Minnesotas current COVID-19 statistics:

2,349 deaths (21 new)

133,802 positive cases (1,684 new); 118,485 off isolation

2,686,302 tests; 1,770,362 people tested

6.7 percent seven-day positive test rate

Twelve of the 21 deaths reported Sunday were residents of long-term care facilities. Those who died ranged in age from someone in their 30s to someone over 100.

Malcolm said on Friday that 565 people were in hospitals, with 160 needing intensive care. Both numbers were near their late-May highs.

New cases are up dramatically over the past month in all age groups. That includes a concerning rise in the number of new cases among Minnesotans ages 60 and older.

People in their 20s still make up the age bracket with the states largest number of confirmed cases more than 29,000 since the pandemic began, including more than 16,600 among people ages 20-24.

The numbers help explain why experts remain particularly concerned about young adults as spreaders of the virus.

While less likely to feel the worst effects of the disease and end up hospitalized, experts worry youth and young adults will spread it to grandparents and other vulnerable populations and that spread could hamper attempts to reopen schools and campuses completely to in-person teaching.

The number of high school-age children confirmed with the disease has also grown, with more than 11,900 total cases among children ages 15 to 19 since the pandemic began.

Regionally, central, northern and southern Minnesota have driven much of the recent increase in new cases while Hennepin and Ramsey counties show some of the slowest case growth in the state.

Newly reported cases are highest in western Minnesota the northwest, west-central and southwest areas of the state have been averaging more than 40 new cases per day per 100,000 people, higher than any of the states central and eastern regions.

The data dont explain why. However, cases are surging currently in the Dakotas. North Dakota has the countrys worst per-capita spread rate.

Collectively, rural areas of Minnesota continue to report the most new COVID-19 cases.

Northern Minnesota, once the region least affected by the disease, has also seen its caseload grow dramatically in recent weeks. Northwestern Minnesota continues to see cases rise swiftly relative to it population.

The largest current hot spot counties are all in northwestern Minnesota:

We are seeing more deaths in greater Minnesota because we are seeing more cases there, Kris Ehresmann, the states infectious disease director, said Wednesday. We will see more and more deaths from greater Minnesota because of the high caseload.

Ehresmann and Malcolm tied the recent steep rise in cases and deaths to COVID fatigue but also described people who are ill but refuse to get tested because they don't want to admit they have it and don't quarantine as a contributing factor in spreading the disease.

In Minnesota and across the country, COVID-19 has hit communities of color disproportionately hard in both cases and deaths.

Minnesotans of Hispanic descent are testing positive for COVID-19 at about five times the rate of white Minnesotans. They, along with Black Minnesotans, are also being hospitalized and moved to intensive care units at higher rates than the overall population.

Similar trends hold true for Minnesotas Indigenous residents. Counts among Indigenous people have jumped in October relative to population. The number of new COVID-19 cases among Native Americans has grown by about 75 percent in the past month.

Data the past two weeks also show newly confirmed cases continuing to accelerate among Latino people in Minnesota.

Distrust of the government, together with deeply rooted health and economic disparities, have hampered efforts to boost testing among communities of color, particularly for undocumented immigrants who fear their personal information may be used to deport them.

As Minnesota continues to see more than 1,000 newly confirmed COVID-19 cases a day, state health officials have scheduled another round of free testing sites this week.

Free testing will take place Tuesday, Wednesday and Thursday in Little Falls, Red Wing and Waconia, as well as Tuesday in Tyler, Thursday in Madison and Thursday and Friday in St. Paul.

Find more details and schedule an appointment on theMinnesota Department of Health website.

Officials said the free testing sites are targeted to areas with COVID-19 outbreaks, or barriers to accessing existing test sites.

Free saliva testing sites are now open in Duluth, Winona, Moorhead, Brooklyn Park and Mankato.Find more information here.

MPR News Staff

As school districts across Minnesota continue to monitor the latest COVID-19 trends, the state's largest district is among those changing its learning model.

The Anoka-Hennepin district announced Friday that its middle schools and high schools will move to distance learning starting Nov. 4, in response to local COVID-19 data. Elementary schools will remain in the hybrid learning model.

Those formats will remain in effect for at least a month.

The move to distance learning means high school activities and athletics will be canceled for the rest of the trimester in the Anoka-Hennepin district.

Schools across Minnesota are getting data and guidance from the state Health Department to help decide whether to have in-person learning, distance learning, or a hybrid of the two and whether to adjust those models as the pandemic continues.

MPR News Staff

The Minnesota Department of Health on Thursday launched an at-home saliva testing pilot program in two dozen counties or tribal nations around the state. Most locations have few testing options and many are in greater Minnesota, where spread of the virus has been rapid in recent weeks.

The state has contracted with Vault Health to provide the saliva tests, which have been rolled out at in-person collection sites around the state.

People in these counties will be able to order the same test through the mail. It will be shipped to their home and performed with the help of a health care professional over the internet. The test will then be shipped to a facility in Oakdale, and results will be available electronically in 24-48 hours.

Test-takers will be asked for insurance information, but it will be free if insurance won't cover it or if they don't have insurance.

Catharine Richert | MPR News

Minn. nursing homes in rural areas see staff shortages worsen with COVID-19: Facilities caring for older adults are struggling with low staffing levels, as COVID-19 makes an ongoing problem even worse. Nursing home operators say theyre scrambling to make sure they have enough nurses and others to ensure the safety and well-being of residents.

Several types of COVID tests are available in Minnesota. What you need to know: Heres a breakdown of the kinds of tests available in the state, when you should seek one out and what happens next.

Data in these graphs are based on the Minnesota Department of Health's cumulative totals released at 11 a.m. daily. You can find more detailed statistics on COVID-19 at theHealth Department website.

You make MPR News possible. Individual donations are behind the clarity in coverage from our reporters across the state, stories that connect us, and conversations that provide perspectives. Help ensure MPR remains a resource that brings Minnesotans together.

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Latest on COVID-19 in MN: Nearly 4,000 more cases, 35 deaths over the weekend - Minnesota Public Radio News

The Trump Administration Shut a Vaccine Safety Office Last Year. Whats the Plan Now? – The New York Times

October 26, 2020

As the first coronavirus vaccines arrive in the coming year, government researchers will face a monumental challenge: monitoring the health of hundreds of millions of Americans to ensure the vaccines dont cause harm.

Purely by chance, thousands of vaccinated people will have heart attacks, strokes and other illnesses shortly after the injections. Sorting out whether the vaccines had anything to do with their ailments will be a thorny problem, requiring a vast, coordinated effort by state and federal agencies, hospitals, drug makers and insurers to discern patterns in a flood of data. Findings will need to be clearly communicated to a distrustful public swamped with disinformation.

For now, Operation Warp Speed, created by the Trump administration to spearhead development of coronavirus vaccines and treatments, is focused on getting vaccines through clinical trials in record time and manufacturing them quickly.

The next job will be to monitor the safety of vaccines once theyre in widespread use. But the administration last year quietly disbanded the office with the expertise for exactly this job, merging it into an office focused on infectious diseases. Its elimination has left that long-term safety effort for coronavirus vaccines fragmented among federal agencies, with no central leadership, experts say.

Were behind the eight ball, said Daniel Salmon, who served as the director of vaccine safety in that office from 2007 to 2012, overseeing coordination during the H1N1 flu pandemic in 2009. We dont even know whos in charge.

An H.H.S. spokesperson said that the vaccine office was not shuttered. The office was not closed, but was merged with the Office of Infectious Disease and HIV/AIDS Policy and was strengthened, the spokesperson said in a statement. All the functions continue in this new organizational structure.

In a brief statement, a different spokesperson said that Operation Warp Speed was working closely with the Centers for Disease Control and Prevention to synchronize the IT systems involved in monitoring vaccine safety data.

Scientists at the C.D.C. and the Food and Drug Administration have decades of experience tracking the long-term safety of vaccines. Theyve created powerful computer programs that can analyze large databases.

Its like satellites looking at the weather, said Dr. Bruce Gellin, the president of the Sabin Vaccine Institute, who headed the National Vaccine Program Office from 2002 to 2017.

But monitoring hundreds of millions of Americans who may get different coronavirus vaccines from a variety of drug makers by summer is like tracking a major storm beyond anything researchers have dealt with before.

The closest parallel was in the spring of 2009, when a new strain of H1N1 influenza emerged, and researchers raced to make a vaccine. From October 2009 to January 2010, it was administered to over 82 million people in the United States.

As the vaccine was developed, Dr. Gellin and other federal officials and scientists organized a system to monitor the population for severe side effects and to promptly share results with the public. Eleven years later, it looks like the lessons of 2009 are being forgotten, experts say.

We got all these different agencies together, we created governance around it, we created a regular monitoring plan, as well as a public communication plan, said Dr. Jesse Goodman, the F.D.A.s chief scientist during the H1N1 pandemic. I think that something very much like that is even more needed now. And, you know, we havent yet seen that emerge.

In the 1970s, the U.S. government set up large-scale programs to monitor vaccine safety. There was a system for parents to report symptoms their children experienced after getting a vaccine. It may get 50,000 reports from parents, doctors, hospitals and vaccine makers in a typical year. But the tool has limits: People may not report symptoms that should be investigated, or may see a connection to a vaccination where none exists.

People are vaccinated one day, and the next day they have some bad medical event, and then they scratch their head and say, Well, you know, I was fine until this happened, Dr. Gellin said.

In 1990, the C.D.C. set up a new way to track vaccines that didnt depend on people coming forward. The agency worked with health care organizations to get updates on peoples medical conditions. That system now covers 12 million people. Researchers can use it to look for clusters of symptoms that arise in people who get the same vaccine.

When the H1N1 flu hit in 2009, Dr. Salmon recognized that these methods didnt track enough people to quickly pick up rare symptoms. He reached out to researchers at Harvard to build a new system, which came to be known as PRISM. Ten states supplied vaccination records, and five health insurance companies shared anonymous information about 38 million members. PRISM then connected the two databases to track insurance claims in the wake of vaccination. That really gave us a ton of data, Dr. Salmon said.

The researchers could come up with a background rate of a host of medical conditions. If the H1N1 vaccine was linked to cases that matched the background rate, they could dismiss the symptoms as ordinary. Only if they rose above the background rate would they be considered unusual and warrant a closer look.

Scientists from various federal agencies gathered every two weeks to share data and look for worrying clusters of symptoms. Every month, outside experts reviewed the evidence and released public reports. Vaccine programs are contingent on trust, Dr. Gellin said, and transparency is a huge element of that.

The vast majority of reports turned out to have nothing to do with the new vaccines. Just a handful of medical conditions required an intensive review. The researchers noticed that some vaccinated people developed a facial weakness called Bells palsy, for example, but within two weeks they ruled out vaccines as the cause.

In the following years, as emerging viruses caused outbreaks of Ebola, MERS and other diseases, experts called for more preparations for the next pandemic. In 2016, President Barack Obama set up a global health security office at the National Security Council. But in 2018, the Trump administration disbanded that office, saying it was streamlining bureaucratic bloat.

The next year, the National Vaccine Program Office met a similar fate. Alex M. Azar II, the secretary of health and human services, said in a letter to Senator Patty Murray, the ranking member of a health subcommittee, that the merger, as part of a broader department reorganization, would increase operational efficiencies by eliminating program redundancies and decreasing program costs.

The offices were merged after a study by career staff who recommended to the Assistant Secretary for Health that this was the best way to improve the function of both offices by creating synergies and eliminating stovepipes, said Admiral Brett Giroir, assistant secretary for health, in a brief statement. I wholeheartedly concurred with this recommendation because strengthening vaccine effectiveness and confidence and ending the H.I.V. epidemic are two of my most critical priorities. Anyone who is suggesting that we closed this office has no clue what theyre talking about.

But Dr. Nicole Lurie, who was assistant secretary for preparedness and response at H.H.S. during the 2009 pandemic, said the loss of the vaccine safety office was especially costly once the coronavirus pandemic hit. The coordinated leadership for stuff like this would likely come from the National Vaccine Program Office, she said.

Dr. Lurie, now an adviser at the Coalition for Epidemic Preparedness Innovation, has been waiting along with other researchers, month after month, for coordinated leadership to emerge from the federal government on long-term vaccine safety. There are a whole bunch of people who were really concerned about this, she said.

An F.D.A. official who declined to be identified said that in the absence of the National Vaccine Program Office, F.D.A. and C.D.C. staff members were relying on relationships they had built across the agencies, meeting regularly to discuss their separate projects.

That leaderless effort concerns Dr. Lurie. Theres no sort of active coordination to bring all the information together, she said.

On Thursday, an expert from the C.D.C. and another from the F.D.A. gave presentations about monitoring systems at a meeting of the F.D.A.s vaccine advisory committee. One system will use smartphone apps to stay in touch with health and other essential workers after their vaccinations. Another will look at a database of electronic health records and insurance claims, and yet another will use Centers for Medicare & Medicaid data to track people over 65.

Although each system may reveal important clues, they have limits that worry outside experts. Dr. Steven Black, the co-director of the Global Vaccine Data Network, observed that the Medicare system only registers billing information, resulting in a time lag. The patient has to get into the hospital, leave the hospital and a bill needs to be sent, he said.

The other systems can provide safety information much faster, but theyre small compared with the PRISM system, which now covers about 60 million people. The F.D.A. still uses PRISM for drug safety research, but not for vaccines. Dr. Salmon is baffled that the agency hasnt tapped into it again. Why would you not use that? he asked. (An agency spokeswoman said it might use PRISM in the future should the need arise.)

The F.D.A. official said the agencies were still building lists of symptoms they plan to track closely. The C.D.C.s list includes conditions like strokes and seizures. But it is also including entirely new conditions the coronavirus causes, like Multisystem Inflammatory Syndrome, which affects many organs at once.

The agencies are searching the scientific literature to estimate the background rates of these outcomes. But Dr. Salmon warned that lockdowns and other disruptions have made some conditions more common and others less so. Comparing the health of vaccinated people with that of people from before the pandemic may set off false alarms.

Dr. Salmon and other researchers are concerned that no overarching plan for communicating findings to the public has emerged. The F.D.A. official said the agency would post its updates on its website. A C.D.C. committee will get safety data from the agencies and discuss the results at public meetings.

But that may fall short of whats needed to foster public confidence. A poll conducted earlier this month by Stat and The Harris Poll found that 58 percent of Americans said they would get vaccinated as soon as a vaccine was available, down from 69 percent in August.

The explosion of disinformation on social media will make clear communication vital. I think that preparing for Russian disinformation campaigns should be part of preparing for the rollout of a Covid vaccine, said Steven Wilson, a political scientist at Brandeis University.

Dr. Grace Lee, a professor at the Stanford University School of Medicine and a member of the C.D.C. committee, agreed that such preparations were urgent, but said they were beyond the committees scope: A national communication strategy and plan is much needed.

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The Trump Administration Shut a Vaccine Safety Office Last Year. Whats the Plan Now? - The New York Times

Fighting Covid-19, With Dolly Parton and The Rock – The New York Times

October 26, 2020

Allison P. Wheeler is an assistant professor of pathology, microbiology and immunology at Vanderbilt and one of the principal investigators of a convalescent plasma trial at Vanderbilt that was launched with Ms. Partons funding. Through a $34 million National Institutes of Health grant, that research was later expanded to 51 additional sites around the country. The teams goal is to treat 500 patients with convalescent plasma and 500 others with a placebo.

I am overwhelmed by the donor response to our study, Dr. Wheeler said. This has been a hard year for everybody, and seeing how much people really want to help has been a high point for me. But blood is a limited resource. At this time, we absolutely couldnt give convalescent plasma to everyone who may benefit. We just wouldnt have enough plasma.

Enter The Rock.

The wrestler-turned-movie-star otherwise known as Dwayne Johnson has stepped up to be a spokesman for a public-private initiative called The Fight Is in Us. Mr. Johnson encourages Covid-19 survivors to donate plasma: If you survived it, then youre the heroes we need, he says in a P.S.A. You fought for your life. Now, lets work together to take down Covid-19.

The Food and Drug Administration has not yet approved convalescent plasma as a treatment for Covid-19, but it does allow emergency use in life-threatening cases. Creating a stockpile of convalescent plasma would make it possible to treat many more severely ill patients during resurgences of the virus before a vaccine is widely available. (Donating is possible all over the country. Click here to find out how.)

A caveat: Though the early evidence suggests that Covid reinfections are exceedingly rare, at least within this first year of the pandemic, it is far too soon to believe that surviving the virus means you are safe. You still need to avoid large gatherings. You still need to keep your distance from people outside your immediate household. You still need to wear a mask.

But being a survivor means you can help. Donating plasma takes a couple of hours, and its no more painful than a needle stick. Your own body will replenish the plasma within a day or two, antibodies included.

At my last donation, I watched a friends small, socially-distanced wedding on Zoom while I was connected to the apheresis machine, which was collecting my blood and sorting it into parts plasma, platelets, white blood cells and red blood cells. Nothing says Peak 2020 like donating antibodies while watching someone get married on your phone. It was joyful event, even on a tiny screen. I held my phone with one hand, and I squeezed a ball with the other, helping the blood move through the machine more quickly. I watched my friends promise to love each other through good times and bad, in sickness and in health, and I prayed for their health. For everybodys health.

Joy and hope may not be what you expect to find in a university laboratory, but its what I felt anyway. Joy and hope and relief that there is finally a way to help.

Margaret Renkl is a contributing opinion writer who covers flora, fauna, politics and culture in the American South. She is the author of the book Late Migrations: A Natural History of Love and Loss.

The Times is committed to publishing a diversity of letters to the editor. Wed like to hear what you think about this or any of our articles. Here are some tips. And heres our email: letters@nytimes.com.

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Fighting Covid-19, With Dolly Parton and The Rock - The New York Times

Maine schools haven’t been testing students for COVID-19, and that’s probably OK – Bangor Daily News

October 26, 2020

Since Maine schools reopened for the fall, students and staff have had to wear face coverings throughout the day, keep their distance from others, wash their hands frequently and often stick with the same, small group throughout the school day to reduce the risk of the coronavirus spreading.

Widespread virus testing at school, however, hasnt been part of Maine schools strategy to prevent the spread of the coronavirus, even as the state has seen 113 coronavirus cases and four virus outbreaks in public schools over the past month.

Testing doesnt necessarily need to be part of the strategy, according to experts.

Theres no clear answer as to whether schools should regularly test their students and teachers for the coronavirus, as colleges and universities in Maine and across the country are doing. The nations top public health agency acknowledges that schools could benefit from surveillance testing especially in areas where the virus is circulating widely and access to testing is limited but it stops short of recommending it. To the extent there is an answer, it comes down to the resources schools have, the ages of the children they serve and how actively COVID-19 is spreading in their communities.

In Maine, theres generally a high level of access to testing outside of schools, and the virus is spreading less in Maine than in virtually every other state.

Maine is one of eight states that researchers say are conducting enough tests to stem the virus spread, and anyone in Maine over a year old is eligible for a test. And, as of Saturday, Maine had recorded the lowest test positivity rate in the nation over the past week, a sign of a low level of virus transmission even as Waldo County contends with a church-linked outbreak that has forced some schools to pare back in-person instruction and call off the rest of the high school sports season. An average of 0.6 percent of Maine tests had come back positive over the past week compared with the national rate of 5.8 percent, according to the Johns Hopkins Coronavirus Resource Center.

The availability of testing locally is the main reason the Bangor School Department does not see the need to offer testing, said Assistant Superintendent Kathy Harris-Smedberg.

I dont know that having testing at the school would provide a benefit beyond going to the local drive-through testing site near Bangor International Airport, she said.

Maine Center for Disease Control and Prevention Director Nirav Shah pointed to the variety of other actions the states public schools have taken that reduce the need for widespread testing on the level that colleges and universities have undertaken at significant expense.

There are significant differences between colleges and schools, namely, the controls that have been placed within schools to keep students as well as teachers in tight pods as well as significant investments in things like engineering controls to reduce the likelihood of transmission, Shah said.

Most Maine schools have stayed open throughout the nearly two months students have been back for in-person learning, with a handful shutting down temporarily in response to outbreaks and individual virus cases. Across the country, schools dont appear to have become the major sources of COVID-19 transmission that many had feared. Elementary schools especially have seen relatively few infections.

But virus conditions can change quickly.

My worry is that just because things have been so calm and quiet in Maine so far doesnt mean theyre going to stay that way, said Matthew Fox, a professor of epidemiology and global health at Boston University. And the key to really being on top of things and being able to identify where outbreaks are happening and what to do about it is testing. I do think schools are a good place to be identifying where contact is happening, and therefore it is a reasonable place to be doing testing.

Perhaps the main limitation for public schools is the cost of carrying out that surveillance testing.

The University of Maine System, with 30,000 students at seven universities, is spending $6 million on its testing program, through which its tested all students living in dorms and tests 2,000 randomly selected students and employees every 10 days throughout the semester. Maines public schools, by contrast, have more than 180,000 students spread across nearly 600 schools.

Relative to something like wearing masks, which is relatively cheap, testing is expensive, said economist Emily Oster, who co founded the COVID-19 School Response Dashboard, which tracks case data at K-12 schools across the country. Its about thinking about what else youre not going to do if you spend money on testing.

For example, if a district has to choose between improving ventilation in school buildings improved flow of clean air can dilute potential contaminants or testing students and staff, it might favor ventilation upgrades.

If districts do decide to conduct widespread testing, they might choose to target the testing at older students, Oster and Fox said.

We have pretty good evidence that younger kids are kind of, on average, a bit less likely to transmit [the virus] and that high school kids are probably not much different than adults, Oster said. Because we know that high schools have on average more cases than younger kids schools, they should probably focus testing on [high schools] if schools are resource-constrained.

As much of the nation sees another spike in COVID-19 cases, schools can use this semester to evaluate what works best to keep schools open. Ideally, data collected from testing students and staff multiple times a week would be a strong indicator of how widely the virus is transmitting in the broader community and would help schools make decisions for the next semester, Fox said.

In general, it would be great for schools to be able to learn from other schools and sort of see what works, Oster said. For places like Maine that have fairly low prevalence, if youre worried whats going to happen if your positivity rate goes up to 5 percent, for example, you have a lot of places you can look at.

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Maine schools haven't been testing students for COVID-19, and that's probably OK - Bangor Daily News

Provosts WAVE Council to host listening sessions on COVID-19 related gender equity concerns – Vanderbilt University News

October 26, 2020

The Provosts WAVE Council will hold two listening sessions the first week of November for faculty and postdoctoral fellows to discuss gender equity concerns related to the COVID-19 pandemic.

The university has implemented many support mechanisms in response to the pandemic, such as the Vanderbilt Strong Faculty Grant Program, Employee COVID-19 Emergency Relief Fund and additional on-campus child care opportunities. The upcoming listening sessions are designed to continue the universitys momentum of support.

Women of academia have been disproportionately affected by the constraints of the pandemic, said Cindy Kam, council chair and William R. Kenan, Jr. Professor of Political Science. Increased child care responsibilities and disrupted work and research environments are just a few of the challenges women in our community are working to overcome. I look forward to discussing continued concerns in our WAVE listening sessions, with the goal of understanding how we can best support and serve the women of Vanderbilt during this challenging time.

The sessions will be hosted via Zoom by Kam and chair-elect Catherine Gavin Loss, associate dean for academic affairs and professional education at Peabody College and associate professor of the practice of leadership, policy and organizations.

The listening sessions schedule is listed below. Theres also a link to submit gender equity concerns for those who are unable to attend a listening session.

Staff members can submit feedback to the Staff WAVE Council via a form on its webpage.

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Provosts WAVE Council to host listening sessions on COVID-19 related gender equity concerns - Vanderbilt University News

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