Canada reports more H5N5 avian flu virus detections in mammals, wild birds – University of Minnesota Twin Cities

Federal health officials and their state and local health partners are investigating reports of harmful reactions in women who received counterfeit or mishandled botulinum toxin (Botox) injections, with 19 injuries reported in nine states, the US Centers for Disease Control and Prevention (CDC) announced yesterday.

The reactions occurred following Botox injections from unlicensed and untrained people in non-healthcare settings, including homes and spas. The patients are from Colorado, Florida, Illinois, Kentucky, Nebraska, New Jersey, New York, Tennessee, and Washington.

Botox contains minute amounts of botulinum toxin, which comes from the bacterium Clostridium botulinum. The toxin, which in larger amounts can cause muscle paralysis, in very small amounts is used to smooth wrinkles and treat certain muscle conditions.

Examples of the patients' reactions include vision problems, drooping eyelids, difficulty swallowing, difficulty breathing, and general weakness. Nine were hospitalized, and four were treated with botulinum antitoxin owing to concerns that botulinum could spread beyond the injection site. Five people were tested for botulism, and all were negative.

All patients were women ages 25 to 59, and all but one received the injections for cosmetic purposes.

Some women received counterfeit or unverified products, and investigators are still working to determine the sources. In a separate statement, the Food and Drug Administration (FDA) said it is working with AbbVie, the Botox manufacturer, to identify, investigate, and remove suspected counterfeit products. It added that there is no sign that the events were related to AbbVie's FDA-approved products.

The CDC urged people considering Botox injections to ensure that providers are licensed and trained and to ask if the product is approved by the FDA and obtained from a reliable source. "If in doubt, dont get the injection," the agency added.

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Canada reports more H5N5 avian flu virus detections in mammals, wild birds - University of Minnesota Twin Cities