Hot Topics in IPC with Saskia v. Popescu, PhD, MPH, MA, CIC, FAPIC
Influenza and COVID-19 Activity
This is the winter where we expect a tripledemicCOVID-19, influenza, and respiratory syncytial virus, but are we there yet? Its still early in the respiratory virus season (usually, it starts to hit in later November), but some of the indicators are pointing to hopefully a moderateand not severerespiratory syndrome. In terms of COVID-19, the CDC is reporting some key metrics we can take into consideration.
First, the US has an 8.7% test positivity, a slight downward trend from October 15 to 21, 2023, which is the latest reported. Regarding emergency department visits diagnosed with COVID-19, the rate is sitting at 1.3%, down 4.6% from the previous week. What is concerning, though, is that 2.7% of all deaths in the US are due to COVID-19 (during the October 15 to 21 week), which is an increase of 12.5%. In terms of wastewater reporting, the number of sites reporting has dropped, which is concerning, and theres been an increase in virus levels, all of which should be worrisomedata is critical!
This week in influenza, were seeing a relative hold at 1.7% of clinical lab results being positive for influenza (most being influenza A H1N1). There have been over 44k specimens tested during week 42 (again, the week ending October 21st). What is often a canary in the coal mine is outpatient respiratory illness rates; this is up and sitting at 2.5%, and something to watch. If we consider what our colleagues in Australia experienced during their influenza season, it will likely be moderate and hopefully end earlier.
All in all, this is an important time to ensure staff are vaccinated, masking and visitor restriction protocols are in place, and you have solid data metrics to determine actions. Regarding vaccinations, were still seeing challenges for many individuals getting the newest booster and with pandemic fatigue. Its still important for folks to get vaccinated. While its likely we wont see a COVID-19 winter similar to what weve already experienced, over time, this drop in immunity due to lackluster vaccination rates could cause larger issues. Its also helpful to ensure staff have disinfecting wipes out and are reminded that this is for them to. Use them to wipe down the workstations, high-touch surfaces, etc.
Mechanical Ventilation and Drug-Resistant Pathogens
Theres an insightful article that has been recently published in the Journal of the American Medical Association that discussed the results of a point prevalence study of those patients receiving mechanical ventilation and test positivity for Candida auris, Acinetobacter baumannii(A baumannii), as well as carbapenem-resistantA baumannii(CRAB). In their findings, the researchers noted that among the 482 patients who had samples collected, 30.7% (148/482) grewA baumannii; 88 of the 148 (59.5%) of theseA baumanniiwere CRAB. In acute care hospitals, 8.2% (23/282) of patients sampled hadA baumanniicompared with 62.5% (125/200) in long-term care facilities (RR, 7.66 [95% CI, 5.11-11.50],P<.001). For CRAB, 6.4% (18/282) of patients sampled in acute care hospitals were colonized compared with 35.0% (70/200) of patients in long-term care facilities (RR, 5.48 [95% CI, 3.38-8.91],P<.001).
I discussed the findings with one of the researchers, Anthony Harris, MD, MPH, which you can read here in Infection Control Todays sister brand, ContagionLive ultimately, we need to start doing more surveillance on vented patients and consider stronger infection prevention and control interventions.
Another tidbit of Knowledge You Might Find Interesting
Chronic Wasting Disease (CWD) Reported in Michigan Deer Thats right, a 4-year-old doe was diagnosed with CWD, which has been found in several Michigan counties.
Read more here:
Hot Topics in IPC: Influenza, COVID-19, and Mechanical Ventilation ... - Infection Control Today
- Biohackers Are on a Secret Hunt for the Coronavirus Vaccine - Reason [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Can synthetic biology protect us from coronavirus? And the next one? - Big Think [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- When will there be a coronavirus vaccine and who will get it first? - Yahoo News [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- These nine companies are working on coronavirus treatments or vaccines heres where things stand - MarketWatch [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Vaccine At Least a Year Away, But Treatment Could Be Here in Months - Newsweek [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus Drug and Vaccine Studies Are Recruiting Their First Volunteers - TIME [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Brexit means coronavirus vaccine will be slower to reach the UK - The Guardian [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- First patient injected in trial of coronavirus vaccine - WCVB Boston [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- A coronavirus vaccine is in the making But you may have to check your pockets first - Duke Chronicle [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus vaccines and treatment: Everything you need to know - CNET [Last Updated On: March 16th, 2020] [Originally Added On: March 16th, 2020]
- Coronavirus outbreak: How much testing should we do, and where are we on developing a vaccine? - Economic Times [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus Vaccines Precision Vaccinations [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- How Long Will It Take to Develop a Vaccine for Coronavirus? [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- California lab says it discovered coronavirus vaccine in 3 hours [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Coronavirus outbreak in Wuhan, China: Vaccine may be ready in ... [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- Everything You Need to Know About Canine Coronavirus Vaccine [Last Updated On: March 17th, 2020] [Originally Added On: March 17th, 2020]
- CSU Researchers Are Working Full-Bore On The Mysteries Of Coronavirus And A Vaccine - Colorado Public Radio [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- How soon will we have a coronavirus vaccine? The race against covid-19 - New Scientist [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Coronavirus trial vaccine participant says he wants to help the world - CNN [Last Updated On: March 18th, 2020] [Originally Added On: March 18th, 2020]
- Daily briefing: The five questions that scientists hunting a coronavirus vaccine must answer - Nature.com [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Baltimore scientists to work on third experimental coronavirus vaccine - Baltimore Sun [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- The coronavirus could kill millions of Americans: 'Do the math,' immunization specialist says - CNBC [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- We're still in the early days of coronavirus vaccine research - Axios [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Inoculating the Coronavirus Vaccine Against the Profit Pandemic - The New Republic [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Wanted: People Willing to Get Sick to Find Coronavirus Vaccine - The Wall Street Journal [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Coronavirus vaccine trial, Mars rover delay and a boost for UK science - Nature.com [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Thousands of scientists are racing to find a vaccine for coronavirus. 41 possibilities are in the works. - The Californian [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- 'I Wanted To Do Something,' Says Mother Of 2 Who Is First To Test Coronavirus Vaccine - NPR [Last Updated On: March 21st, 2020] [Originally Added On: March 21st, 2020]
- Vaccine Trials To Fight Coronavirus Offer Hope, Could Be Harbinger Of New Technology - Outlook India [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- Image of COVID-19 test kit shared as newly developed 'coronavirus vaccine' by Roche - Alt News [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- A coronavirus vaccine is the only thing that can make life 'perfectly normal' again, former FDA commissioner says - The Week [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- Johnson & Johnson CEO on potential coronavirus vaccine: 'I think we'll have important data by the end of the year' - Fox News [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- As the First Coronavirus Vaccine Human Trials Begin, Manufacturer Is Already Preparing to Scale Production to Millions - TIME [Last Updated On: March 23rd, 2020] [Originally Added On: March 23rd, 2020]
- A coronavirus vaccine is the only thing that can make life 'perfectly normal' again, former FDA commissioner says - Yahoo News [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- This Vaccine Could Save Health Care Workers From the Coronavirus - Foreign Policy [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Coronavirus vaccine must be affordable and accessible - The Conversation CA [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Over 100 drugs are in testing in the race to treat coronavirus - Axios [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- This is when the first coronavirus drugs might actually be available - BGR [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Another Day, Another Meme to Debunk: Vaccines for the Bovine Coronavirus Will Not Cure COVID-19 - Mother Jones [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- A Coronavirus Vaccine Could Be the First That Outwits Nature - Singularity Hub [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Coronavirus treatment other than vaccines may be available soon - The Jerusalem Post [Last Updated On: March 25th, 2020] [Originally Added On: March 25th, 2020]
- Coronavirus: Vaccine hopes given boost as researcher says virus not mutating - The Independent [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Coronavirus Vaccine Is Critical, The Infection Could Become Seasonal, Researchers Warn - NDTV News [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- A coronavirus vaccine from Virginia? These researchers are working on it. - The Virginian-Pilot - The Virginian-Pilot [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Scientists, under pressure, try to balance speed and safety on coronavirus vaccine research - NBCNews.com [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Should scientists infect healthy people with the coronavirus to test vaccines? - Nature.com [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Coronavirus Vaccines May Not Work for the Elderlyand This Lab Aims to Change That - Scientific American [Last Updated On: March 27th, 2020] [Originally Added On: March 27th, 2020]
- Vaccine Development Is Risky Business. Biotechs Are Tackling The Coronavirus, Anyway - WBUR [Last Updated On: March 29th, 2020] [Originally Added On: March 29th, 2020]
- Coronavirus vaccine: how soon will we have one? - World Economic Forum [Last Updated On: March 29th, 2020] [Originally Added On: March 29th, 2020]
- USC Working on Coronavirus Vaccine, Researchers Announce - NBC Southern California [Last Updated On: March 29th, 2020] [Originally Added On: March 29th, 2020]
- Tracking the development of coronavirus treatments - NBC News [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- In the fight against coronavirus, antivirals are as important as a vaccine. Here's where the science is up to - The Conversation AU [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- Johnson & Johnson Says It Could Have Coronavirus Vaccine Ready by Early 2021 - The Daily Beast [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- Coronavirus: when will the vaccine be ready? - AS South Africa [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- A Coronavirus Vaccine Is Coming, And It Will Work - City Journal [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- With record-setting speed, vaccinemakers take their first shots at the new coronavirus - Science Magazine [Last Updated On: April 1st, 2020] [Originally Added On: April 1st, 2020]
- CDC: Coronavirus Vaccine Will Be Ready for Refusal By Anti-Vaxxers By 2021 - MedPage Today [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- The race to find a coronavirus treatment has one major obstacle: big pharma - The Guardian [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- Why A Coronavirus Vaccine May Be Years Away - The National Interest [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- The race is on for coronavirus vaccines and treatments: current R&D status - The Pharma Letter [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- Tests of potential coronavirus vaccine spur growth of virus-fighting antibodies - USA TODAY [Last Updated On: April 3rd, 2020] [Originally Added On: April 3rd, 2020]
- A 100-yr-old vaccine is being tested against the new coronavirus. Can it work? - Economic Times [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Coronavirus Live Updates: Boris Johnson Moved to Intensive Care and the U.S. Death Toll Surpasses 10,000 - The New York Times [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- When will a coronavirus shot be ready? A look at the vaccine race. - WRAL.com [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Hulk Hogan on coronavirus: Maybe we dont need a vaccine - Tampa Bay Times [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- White House advisor Fauci says coronavirus vaccine trial is on target and will be 'ultimate game changer' - CNBC [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Coronavirus vaccine will take time, so researchers are hunting for and finding promising new COVID-19 tre - OregonLive [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Chester County to begin testing for coronavirus antibodies; British prime minister moved to intensive care - The Philadelphia Inquirer [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- MAP: Where coronavirus treatments and vaccines are being tested on patients in the US - Business Insider - Business Insider [Last Updated On: April 6th, 2020] [Originally Added On: April 6th, 2020]
- Coronavirus pandemic: Why it takes so long to make a vaccine - Business Today [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- A vaccine for coronavirus is the goal, but what does it take to get there? - ABC News [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- Trump says there's light at the end of the tunnel with coronavirus vaccine and treatment research - CNBC [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- Russia Ready to Start Testing Coronavirus Vaccines on Humans in June - The Moscow Times [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- Why a coronavirus vaccine takes over a year to produce and why that is incredibly fast - World Economic Forum [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- Pandemic expert calls for manufacturing coronavirus vaccines before they're proven to work - The Week [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- More Coronavirus Vaccine Efforts Move Toward Human Trials - The New York Times [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- A coronavirus vaccine is being developed in record time. But don't expect that technology to speed up flu vaccines yet. - USA TODAY [Last Updated On: April 8th, 2020] [Originally Added On: April 8th, 2020]
- A New Front for Nationalism: The Global Battle Against a Virus - The New York Times [Last Updated On: April 10th, 2020] [Originally Added On: April 10th, 2020]
- Here's how your body gains immunity to coronavirus - The Guardian [Last Updated On: April 10th, 2020] [Originally Added On: April 10th, 2020]
- Pfizer aims to create coronavirus vaccine by end of 2020 - MLive.com [Last Updated On: April 10th, 2020] [Originally Added On: April 10th, 2020]