COVID-19 vaccine: FAQ | Arizona State University

Getting the vaccineWhy should I get vaccinated?

For those in the ASU community, ASU Health ServicesandEmployee Healthhave COVID-19 vaccines, third doses and boosters available.

Students can make appointments by going to theASU Health Portal; ASU Health Services has the Moderna and Johnson & Johnson vaccines available.

ASU employees can make appointments throughEmployee Health; Employee Health has the Moderna vaccine only.

All COVID-19 vaccines are widely available across pharmacies, supermarkets and medical providers. To find a convenient location near you to get a COVID-19 vaccine dose or booster, please visitvaccines.gov/searchorazdhs.gov/FindVaccine. You can also call 1-800-232-0233 (TTY 1-888-720-7489).

Refer to theCDCorFDAfor the most current information on the COVID-19 vaccine dose, and booster details and timing; all university employees are eligible for the COVID-19 booster.

For the most part, yes (see below forexceptions). The Centers for Disease Control and Preventionrecommendthat everyone be offered thevaccine, regardless of whether they have been infected. It is unclear how long natural immunity lasts after someone recovers from an infection.

There isguidanceon exceptionsfrom the CDC on the following:

Those with known current COVID-19 infection:Vaccination should be deferred until the person has recovered from the acute illness (if the person had symptoms) and criteria have been met for them to discontinue isolation. This recommendation applies to people who develop a COVID-19 infection before receiving any vaccine doses, as well as those who develop an infection after the first dose but before receipt of the second one.

Those with known COVID-19 exposure:Vaccination is unlikely to be effective in preventing disease after an exposure because the median incubation period of COVID-19 is four to five days, it is unlikely that the first dose of the vaccine would provide an adequate immune response within the incubation period for effective post-exposure prophylaxis (that is, vaccination to prevent the development of COVID-19). People in the community or outpatient setting who have had a known COVID-19 exposure should not seek vaccination until their quarantine period has ended to avoid potentially exposing health care personnel and other persons during the vaccination visit.

Those who have received passive antibody therapy(that is, who have received monoclonal antibodies or convalescent plasma from individuals who have recovered from an infection): Based on the estimated half-life of such therapies as well as evidence suggesting that reinfection is uncommon in the 90 days after initial infection, vaccination should be deferred for at least 90 days, as a precautionary measure until additional information becomes available, to avoid potential interference of the antibody therapy with vaccine-induced immune responses. This recommendation applies to people who receive passive antibody therapy before receiving any vaccine doses as well as those who receive passive antibody therapy after the first dose but before the second dose, in which case the second dose should be deferred for at least 90 days following receipt of the antibody therapy.

There is no recommended minimum interval between other antibody therapies not specific to COVID-19 treatment (e.g., intravenous immunoglobulin, RhoGAM) and vaccination.

No. Please stay home and reschedule when you are well. Its important to protect the health of the distribution-site staff, as well as other people receiving the vaccine.

No. Your second vaccination needs to be the same vaccine brand as your first (Moderna or Pfizer-BioNTech).

You will need to be observed for 30 minutes after your vaccine dose, rather than the standard 15 minutes.

Consult with your health care provider. If you are on blood thinners, you will need to wait 30 minutes under observation at the vaccination site after receiving your vaccine.

Consult with your OB/GYN and/or pediatrician before receiving any COVID-19 vaccine.

The COVID-19 vaccine is free to everyone living in the United States. You do not need to have health insurance. You do not need to be a U.S. citizen.

No. If you have health insurance, you will be asked to enter your information during the vaccine registration.

Yes time to take the vaccine is considered working time. Employees should try to take it during working hours. Time away from work should be coordinated with and approved by the supervisor with as much notice as possible.

Time should be recorded as regular working time for hourly employees even if it is taken on a weekend and results in overtime. FFCRA pay codes should not be used to account for time to take a vaccine.

For assistance with time reporting questions, contact OHR Partners.

There is no upper age limit for any of the vaccines.

As of November 2021, the Pfizer vaccine has received emergency-use authorization for children as young as 5. The lower age limit for the Moderna and Johnson & Johnsons vaccines is 18.

Yes. ASU does not have access to ADHS records regarding who received the vaccine. To assist in our efforts to manage COVID-19 vaccinations in the ASU community, we are asking those individuals who have been vaccinated touploadtheir vaccination records; the information is kept secure. Employees, including student employees, can do so here; all other students can do so through the Health Portal.

International students can get the vaccine while in the U.S., and it is recommended that they get the vaccine as soon as they are able to.

No. They should bring verification of vaccination with them so that the vaccination site knows which shot they need. You cannot mix vaccine brands, however. ASU cannot guarantee that if someone gets a certain vaccine elsewhere that the same brand will be available here.

The U.S. will only distribute vaccines that have been approved as effective and have received emergency-use designation. Other countries may be using the same or different vaccines, as there are numerous available globally.

The SARS-CoV-2 virus is covered in a crown, or corona, of spike proteins that give coronaviruses their name. The viruses use these spike proteins like keys to get into human cells.

The vaccines train our immune systems to recognize these spike proteins and prepare to defend against them.

There are currently two types of COVID-19 vaccines authorized for use in the U.S. adenovirus and messenger RNA (mRNA) vaccines. Both types use the viruss genetic instructions for building spike proteins to provoke an immune response.

The Johnson & Johnson vaccine contains a common virus called an adenovirus. The virus has been reprogrammed so that it cant replicate or make you sick. Instead, it carries DNA with instructions for the coronaviruss spike protein.

When your cells absorb the adenovirus, they copy the instructions for the spike protein into messenger RNA molecules. The cells use this mRNA like a blueprint to start building spike proteins. The spike proteins make their way to the outside of the cell, where your immune system recognizes them as intruders and mobilizes an immune response.

The Pfizer-BioNTech and Moderna vaccines work in a similar way, but they skip the adenovirus step. Instead of having your cells build the mRNA from DNA, these vaccines give you the mRNA directly.

In both types of vaccines, the genetic instructions are destroyed after use, like a self-destructing Mission Impossible message. However, the antibodies created by your immune system remain. If youre exposed to the coronavirus in the future, your body will recognize the spike protein trying to invade your cells and deploy antibodies in defense.

They are working extremely well.

The intended benefit of the vaccines was to prevent serious illness and death. They are excellent at doing that, says Josh LaBaer, MD, executive director of the Biodesign Institute at ASU.

Although the delta variant is causing more breakthrough infections among vaccinated people than before, the vaccines are still protecting against severe illness. In Arizona, for example, unvaccinated people make up 99.5% of COVID-19 hospitalizations and 99.7% of deaths.

Far and away, all three vaccines are doing an excellent job at preventing hospitalizations and deaths. Thats true everywhere, not just in Arizona, LaBaer says.

Common side effects of the COVID-19 vaccines include fever, chills, fatigue, headache, and pain and swelling at the injection site.But those side effects are short-lived and not cause for concern.

That's a great sign. Symptoms show that your body is creating an immune response to COVID, saysHeather Ross, a clinical assistant professor in ASUs Edson College of Nursing and Health Innovation and School for the Future of Innovation in Society. She participated in the Moderna vaccine clinical trial in summer 2020.

After the first dose, my arm was pretty sore and I had a headache, but not anything serious. After my second dose, about eight hours after the shot I had a fever, I felt super tired and pretty grumpy for about 30 hours. And then I was fine, she says.

I do tell people, vaccination symptoms are a hell of a lot better than getting sick with COVID. I have students, healthy young people, who are still getting short of breath when they try to exert themselves, months after recovering. It can be really, really disabling. Weve seen people getting strokes after the fact from having COVID. It's really scary stuff.

There have been some extremely rare, more severe side effects from the vaccines. These include allergic reactions, blood clots after the Johnson & Johnson vaccine, and myocarditis and pericarditis in adolescents/young adults after the mRNA vaccines.Get up-to-date information about reported side effects here.

It is important to remember that your risk of catching and dying from COVID-19 is far higher than the risk of any of these side effects.

Consult with your doctor before receiving your second dose.

Yes, employees who have side effects can use sick leave.

No. There are no known long-term effects from the COVID-19 vaccines used in the U.S.

More than 356 million doses have been given under the most intense safety monitoring in our countrys history. Anyone can report reactions through theVaccine Adverse Events Reporting System. The CDC, Food and Drug Administration and other federal agencies investigate these reports thoroughly. They have not found any long-term problems caused by the COVID-19 vaccines.

This matches what we know about vaccines in general.

The overwhelming majority of vaccine side effects show up within two months, saysAnna Muldoon, who holds a masters degree in public health and is a PhD student in the School for the Future of Innovation and Society. People don't get weird effects from a vaccine 10 years later. The body doesn't work like that.

I don't worry so much about long-term negative consequences, because we know they are really nonexistent in vaccines. And there's no reason to believe that this vaccine is going to be different from any others, adds Bertram Jacobs, a professor of virology with the School of Life Sciences and a researcher in the Biodesign Center for Immunotherapy, Vaccines and Virotherapy.

On the other hand, COVID-19 is known to have serious, long-term health risks.

Between 15% to 60% of people have long-term side effects of the virus, even people who had mild or asymptomatic infections, says Josh LaBaer, MD, executive director of the Biodesign Institute at ASU. Brain fog, memory problems, respiratory problems, gastrointestinal problems these are showing up more and more. We now know in no uncertain terms that this virus gets into the brain.

If youre worried about long-term side effects, theres much more case for having them from the virus than from the vaccine. Its naive to assume that when you get over the virus youre done with it, he adds.

The Pfizer-BioNTech and Moderna vaccines contain messenger RNA (mRNA), lipids and saline solutions. The single active ingredient mRNA is contained within a protective bubble of lipids. The saline solutions in the two vaccines are used commonly in medications and vaccines and serve to keep the pH and salt levels of the mixture close to those in the human body. Both vaccines are essentially genetic material wrapped in a bubble of fat suspended in salt water.

The full ingredients of the Moderna COVID-19 vaccine are: messenger ribonucleic acid (mRNA), four lipids: SM-102; polyethylene glycol (PEG) 2000 dimyristoyl glycerol (DMG); cholesterol; 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC); and the saline solutions comprised of tromethamine, tromethamine hydrochloride, acetic acid, sodium acetate, and sucrose.

The full ingredients of the Pfizer-BioNTech COVID-19 vaccine are: messenger ribonucleic acid (mRNA), four lipids: (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate); 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide; 1,2-Distearoyl-sn-glycero-3-phosphocholine and cholesterol; and a saline solution of potassium chloride, monobasic potassium phosphate, sodium chloride, dibasic sodium phosphate dihydrate, and sucrose.

The Johnson & Johnson vaccine contains a modified adenovirus with coronavirus DNA, as well as various stabilizers, alcohol for sterilization, an anticoagulant, an emulsifier to hold the ingredients together and salt.

The full ingredients of the Johnson & Johnson vaccine are: recombinant, replication-incompetent adenovirus type 26 expressing the SARS-CoV-2 spike protein, citric acid monohydrate, trisodium citrate dihydrate, ethanol, 2-hydroxypropyl--cyclodextrin (HBCD), polysorbate-80 and sodium chloride.

Polyethylene glycol, or PEG, is a petroleum-derived compound thats found in everything from medicine and food to cosmetics and industrial products. PEG is in both the Pfizer-BioNTech and Moderna vaccines, where its used as a stabilizing agent for the mRNA.

Its used in the vaccines to make sure the active component doesn't fall apart, dry up, degrade or become unusable until it gets delivered to the body, says Biodesign Institute Executive Director Josh LaBaer. Its used in all kinds of substances that we take all the time. Generally speaking, the vast majority of people have no problem with polyethylene glycol, but there are individuals that have allergic reactions to PEG.

The Johnson & Johnson vaccine does not contain PEG, but it does contain polysorbate. A small number of people are allergic to polysorbate.

If you have a history of severe allergic reactions, check theCDC guidelinesto see if you should receive a COVID-19 vaccine.

No. The flu shot does not protect against COVID-19.

Health experts urge people to get their annual flu shot in addition to the COVID-19 vaccine. Especially with so many hospitals at capacity, it's best to do everything possible to prevent either illness.

Its possible. Breakthrough infections cases of COVID-19 in vaccinated people are rare. However, there has been an increase in breakthrough infections from the delta variant. Delta is now the dominant form of the virus in the U.S.

First, no vaccine is perfect. We know that some percent of people dont mount as strong an immune response, says Josh LaBaer, MD, executive director of the Biodesign Institute at ASU.

However, there is another reason why the delta variant may be causing more breakthrough infections.

One of the characteristics of delta is that it is better at elbowing all the other variants out of the way, LaBaer says.

It does this by reproducing very quickly at the beginning of an infection possibly 1,000 times faster than other variants. This early period is also when people are most contagious.

Vaccines produce antibodies that fight the virus. Over time, the antibodies decrease, but our immune systems also have memory B cells that remember how to make them. When memory B cells are exposed to the virus, they start making more antibodies, but this can take a few days.

There is some evidence that people with breakthrough delta infections have high levels of virus at the start, before their B cells kick in and get the virus under control. That may be why vaccinated people tend to have mild cases their memory B cells churn out antibodies before the infection gets out of control. But they could be contagious before this happens.

No.

While the vaccines contain genetic material (mRNA), they have no effect on our DNA. These messenger RNA vaccines, or mRNA, simply deliver instructions to our immune cells to make a single protein from the coronavirus. Once the protein is created, those instructions are broken down and the protein piece is displayed on the surface of a cell. Our immune systems recognize that it doesnt belong and make antibodies in defense, mirroring the natural immune response to an infection.

The mRNA does not remain in the body. Its disposed of once it delivers its instructions and does not impact our DNA.

It is unknown if the COVID-19 vaccines will protect against new strains of SARS-CoV-2. Preliminary research suggests that the Pfizer-BioNTech vaccine will provide protection against the more infectious strain first detected in the United Kingdom.

Pfizer-BioNTech and Moderna vaccines prompt the body to create antibodies tailored to the viruss spike protein, and new strains of the coronavirus are exhibiting changes to that region.

Scientists dont think those changes will be enough to prevent the vaccine from working. What we might see, though, is instead of being 95% effective, maybe the vaccines are 80% effective or 70% effective against the new strains, says Bertram Jacobs, a professor of virology with ASUs School of Life Sciences and a researcher in the Biodesign Institute's Center for Immunotherapy, Vaccines and Virotherapy.

While diminished efficacy is a concern, Jacobs says both the Pfizer-BioNTech and Moderna vaccines can be quickly adapted to protect against emerging strains.

It is worth noting that even though the vaccines have not yet been formally tested on the variants, they are still proving effective when measured in geographical areas that have high rates of variants, adds Biodesign Institute Executive Director Josh LaBaer, pointing to the Johnson & Johnson clinical trial in South Africa.

In the trial, 92% of sequenced cases were the more infectious South African variant of the virus, though the vaccine proved effective in preventing moderate to severe COVID-19 73% of the time at 14 days and 82% at 28 days.

My guess is that the vaccines are going to be effective for a long time, says LaBaer. I'm hopeful, because this is not like the flu virus, which constantly changes its look and its antigens. This virus doesn't change that fast, and the vaccines seem to be pretty broadly effective.

After the vaccine

Continued safety protocols

Yes, if you have symptoms or have been exposed to someone who tested positive. Vaccination is not a golden ticket to never worry about the coronavirus again. The risk of infection is reduced, but not eliminated. And until a greater proportion of the population is vaccinated, testing is a way of making sure people aren't asymptomatically carrying the virus.

Biodesign Institute Executive Director Josh LaBaer, who has been vaccinated, gets tested when the situation calls for it.

If I'm going to be near somebody who hasn't been vaccinated or I travel, or Im heading to an in-person meeting, I'll get tested, he says.

ASU offers free, saliva-based PCR testing on all campuses and throughout Arizona.Find a free COVID-19 test near you.

Its important to continue to get tested. If youve recently received a COVID-19 vaccine, this will not affect your COVID saliva test result. You will still receive an accurate test result.

The saliva test measures the virus itself its genetic material, its RNA and does not have anything to do with the immune system. So nothing about the vaccination would affect that kind of test. If someone is currently infected with virus, whether or not they have been vaccinated, ASU's saliva test will work.

Because the virus changed.

The delta variant is now the main form of the coronavirus in the U.S. It behaves differently than the original virus. Delta is infecting more vaccinated people, and there is evidence that those people can spread the virus.

Vaccinated people are not likely to get severely ill from COVID-19, even from the delta variant. But if they spread the virus to someone who isnt vaccinated, that person could become very sick or die. Vaccinated people should wear masks around others to avoid passing along the virus.

Public health experts change their guidance when situations change, or when we learn new information. During a crisis like a pandemic, people need information quickly about a threat we dont fully understand. We should expect that guidance will change as we learn more and should be prepared to check reliable sources of information regularly.

Getting vaccinated helps us reach herd immunity, which refers to when most of a population is immune to a disease either through vaccination or previous infection. It provides indirect protection to those who arent immune. The percentage of immune people in a population needed to reach herd immunity varies for different diseases and is unknown for COVID-19.

In addition, it is not currently known if the vaccine eliminates asymptomatic infection and transmission. That means those close to you who get vaccinated might still be able to pass along the coronavirus to you, even if it doesn't affect them.

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COVID-19 vaccine: FAQ | Arizona State University